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Searching for up to 100 curated homologs for 14463 FitnessBrowser__Keio:14463 (349 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

Removed hits that are identical to the query, leaving 99

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

1uufA / P75691 Crystal structure of a zinc-type alcohol dehydrogenase-like protein yahk
    98% identity, 99% coverage of query (667 bits)

ADHC1_MYCS2 / P0CH36 NADP-dependent alcohol dehydrogenase C 1; Ms-ADHC 1; EC 1.1.1.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see 2 papers)
ADHC2_MYCS2 / P0CH37 NADP-dependent alcohol dehydrogenase C 2; Ms-ADHC 2; EC 1.1.1.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see 2 papers)
    54% identity, 99% coverage of query (357 bits)

A0A125SUY5 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Mycobacterium sp. (see paper)
    52% identity, 99% coverage of query (356 bits)

adhA / C0SPA5 S-(hydroxymethyl)bacillithiol dehydrogenase (EC 1.1.1.306) from Bacillus subtilis (strain 168) (see 2 papers)
ADHA_BACSU / C0SPA5 Probable formaldehyde dehydrogenase AdhA; EC 1.1.1.- from Bacillus subtilis (strain 168) (see paper)
    54% identity, 97% coverage of query (354 bits)

P9WQC5 NADP-dependent alcohol dehydrogenase C; EC 1.1.1.2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
    52% identity, 99% coverage of query (346 bits)

A1R6C3 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Paenarthrobacter aurescens (see paper)
    53% identity, 99% coverage of query (333 bits)

T1WWR8 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    51% identity, 94% coverage of query (303 bits)

F6L7F5 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Camellia sinensis (see paper)
    51% identity, 94% coverage of query (302 bits)

CADH6_ARATH / O65621 Probable cinnamyl alcohol dehydrogenase 6; AtCAD6; Cinnamyl alcohol dehydrogenase-like protein A; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    48% identity, 94% coverage of query (301 bits)

T1WWB9 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    51% identity, 94% coverage of query (300 bits)

T1WUU2 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    49% identity, 98% coverage of query (300 bits)

A0A1D6BJ11 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Triticum aestivum (see paper)
    49% identity, 97% coverage of query (299 bits)

SAD / Q94G59 sinapyl alcohol dehydrogenase (EC 1.1.1.195) from Populus tremuloides (see paper)
    49% identity, 98% coverage of query (299 bits)

1yqdA / Q94G59 Sinapyl alcohol dehydrogenase complexed with NADP+ (see paper)
    49% identity, 98% coverage of query (299 bits)

T1WVG5 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    48% identity, 98% coverage of query (298 bits)

T1WUT6 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    49% identity, 94% coverage of query (298 bits)

Q9ATW1 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Fragaria x ananassa (see paper)
    52% identity, 94% coverage of query (298 bits)

A0A023RBJ1 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    50% identity, 94% coverage of query (297 bits)

CADH2_ARATH / Q9SJ25 Cinnamyl alcohol dehydrogenase 2; AtCAD2; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    46% identity, 94% coverage of query (295 bits)

GEDH1 / Q2KNL6 geraniol dehydrogenase (EC 1.1.1.183) from Ocimum basilicum (see paper)
GEDH1_OCIBA / Q2KNL6 Geraniol dehydrogenase 1; ObaGEDH1; EC 1.1.1.183 from Ocimum basilicum (Sweet basil) (see paper)
Q2KNL6 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Ocimum basilicum (see paper)
    50% identity, 98% coverage of query (293 bits)

CADH9_ARATH / P42734 Probable cinnamyl alcohol dehydrogenase 9; AtCAD9; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    46% identity, 98% coverage of query (291 bits)

K9S0X0 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Perilla frutescens var. hirtella (see paper)
    50% identity, 94% coverage of query (291 bits)

Q8H0L8 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Solanum tuberosum (see paper)
    50% identity, 94% coverage of query (290 bits)

CADH7_ORYSJ / Q0JA75 Cinnamyl alcohol dehydrogenase 7; OsCAD7; Protein FLEXIBLE CULM 1; EC 1.1.1.195 from Oryza sativa subsp. japonica (Rice) (see paper)
    48% identity, 97% coverage of query (289 bits)

CADH8_ARATH / Q02972 Cinnamyl alcohol dehydrogenase 8; AtCAD8; NAD-dependent mannitol dehydrogenase 2; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    50% identity, 94% coverage of query (289 bits)

K9RZL7 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Perilla frutescens var. hirtella (see paper)
    49% identity, 98% coverage of query (288 bits)

5z0cA / J7JYU1 Nerol dehydrogenase from persicaria minor (see paper)
    49% identity, 98% coverage of query (286 bits)

Q7XWU3 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Oryza sativa Japonica Group (see paper)
    49% identity, 94% coverage of query (286 bits)

K9S1J6 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Perilla frutescens (see paper)
    49% identity, 98% coverage of query (286 bits)

CADH3_ARATH / Q9SJ10 Cinnamyl alcohol dehydrogenase 3; AtCAD3; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    46% identity, 94% coverage of query (286 bits)

MTD / Q38707 mannitol dehydrogenase (EC 1.1.1.255) from Apium graveolens (see paper)
Q38707 mannitol dehydrogenase (EC 1.1.1.255) from Apium graveolens (see paper)
    47% identity, 98% coverage of query (285 bits)

CAD7 / Q02971 cinnamyl alcohol dehydrogenase 7 (EC 1.1.1.195) from Arabidopsis thaliana (see 2 papers)
CADH7_ARATH / Q02971 Cinnamyl alcohol dehydrogenase 7; AtCAD7; Cinnamyl alcohol dehydrogenase-like protein B; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    48% identity, 94% coverage of query (284 bits)

10HGO / Q6V4H0 8-hydroxygeraniol dehydrogenase (EC 1.1.1.324) from Catharanthus roseus (see paper)
10HGO_CATRO / Q6V4H0 8-hydroxygeraniol dehydrogenase; Cr10HGO; EC 1.1.1.324 from Catharanthus roseus (Madagascar periwinkle) (Vinca rosea)
    51% identity, 94% coverage of query (283 bits)

6k3gB / Q6V4H0 Crystal structure of 10-hydroxygeraniol dehydrogenase from cantharanthus roseus in complex with NADP+ (see paper)
    51% identity, 94% coverage of query (283 bits)

Q1HGA8 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Linum usitatissimum (see 3 papers)
    42% identity, 98% coverage of query (283 bits)

T1WW77 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    49% identity, 94% coverage of query (280 bits)

Redox1 / A0A2P1GIW4 Redox 1 from Catharanthus roseus (see paper)
REDX1_CATRO / A0A2P1GIW4 Protein REDOX 1; Cinnamyl alcohol dehydrogenase 4; EC 1.14.14.- from Catharanthus roseus (Madagascar periwinkle) (Vinca rosea) (see 2 papers)
    45% identity, 98% coverage of query (278 bits)

cad / O25732 cinnamyl-alcohol dehydrogenase (EC 1.1.1.2; EC 1.1.1.95; EC 1.1.1.195) from Helicobacter pylori (strain ATCC 700392 / 26695) (see 3 papers)
    42% identity, 99% coverage of query (273 bits)

D0ITF8 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Helicobacter pylori (see paper)
3twoB / D0ITF8 The crystal structure of cad from helicobacter pylori complexed with NADP(h) (see paper)
    42% identity, 99% coverage of query (272 bits)

CADH1_ARATH / Q9CAI3 Probable cinnamyl alcohol dehydrogenase 1; AtCAD1; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    47% identity, 96% coverage of query (266 bits)

CAD1_MEDTR / A0A072VPZ8 Cinnamyl alcohol dehydrogenase 1; Mt-CAD1; Coniferol dehydrogenase; Coumaroyl alcohol dehydrogenase; Sinapyl alcohol dehydrogenase; EC 1.1.1.195 from Medicago truncatula (Barrel medic) (Medicago tribuloides) (see paper)
    43% identity, 96% coverage of query (263 bits)

B5TR18 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Leucaena leucocephala (see paper)
    43% identity, 96% coverage of query (262 bits)

B5AR58 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Leucaena leucocephala (see paper)
    42% identity, 96% coverage of query (260 bits)

7cguA / A0A8A5L0G9 Crystal structure of abhar
    46% identity, 94% coverage of query (260 bits)

5vktA / C5XC49 Cinnamyl alcohol dehydrogenases (sbcad4) from sorghum bicolor (l.) Moench (see paper)
    45% identity, 96% coverage of query (258 bits)

C5XC49 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Sorghum bicolor (see 2 papers)
    45% identity, 96% coverage of query (258 bits)

GS1 / W8JWW7 geissoschizine synthase (EC 1.3.1.36) from Catharanthus roseus (see 2 papers)
GS_CATRO / W8JWW7 Geissoschizine synthase; CrGS; Alcohol dehydrogenase 14; CrADH14; EC 1.3.1.36 from Catharanthus roseus (Madagascar periwinkle) (Vinca rosea) (see 4 papers)
    43% identity, 98% coverage of query (257 bits)

YL498_MIMIV / Q5UQG2 Probable zinc-type alcohol dehydrogenase-like protein L498; EC 1.-.-.- from Acanthamoeba polyphaga mimivirus (APMV) (see paper)
    42% identity, 97% coverage of query (254 bits)

8a3nB / W8JWW7 Geissoschizine synthase from catharanthus roseus - binary complex with NADP+ (see paper)
    42% identity, 98% coverage of query (253 bits)

CAD1 / Q2KNL5 geraniol dehydrogenase (EC 1.1.1.183) from Ocimum basilicum (see paper)
CADH1_OCIBA / Q2KNL5 Cinnamyl alcohol dehydrogenase 1; CAD 1; ObaCAD1; EC 1.1.1.195 from Ocimum basilicum (Sweet basil) (see paper)
    44% identity, 97% coverage of query (249 bits)

G3DSC5 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Liriodendron tulipifera (see paper)
    43% identity, 94% coverage of query (249 bits)

CAD1_CAPAN / B5LAT8 Cinnamyl alcohol dehydrogenase 1; CaCAD1; Vanillyl alcohol synthase; EC 1.1.1.195; EC 1.1.1.- from Capsicum annuum (Capsicum pepper) (see paper)
    43% identity, 97% coverage of query (245 bits)

T3R_CATRO / A0A161CAI1 16-methoxy-2,3-dihydro-3-hydroxytabersonine synthase; 3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine reductase; Alcohol dehydrogenase-like protein 1; ADHL1; Tabersonine 3-reductase; EC 1.1.99.41 from Catharanthus roseus (Madagascar periwinkle) (Vinca rosea) (see 2 papers)
A0A161CAI1 3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine reductase (EC 1.1.99.41) from Catharanthus roseus (see 2 papers)
    41% identity, 94% coverage of query (242 bits)

8b1vA Dihydroprecondylocarpine acetate synthase 2 from tabernanthe iboga
    44% identity, 96% coverage of query (241 bits)

8b25B / A0A5B8X8Z0 Dihydroprecondylocarpine acetate synthase 2 from tabernanthe iboga - stemmadenine acetate bound structure (see paper)
    44% identity, 96% coverage of query (240 bits)

CAD4 / P48523 cinnamyl alcohol dehydrogenase 4 (EC 1.1.1.195) from Arabidopsis thaliana (see paper)
CADH4_ARATH / P48523 Cinnamyl alcohol dehydrogenase 4; AtCAD4; Cinnamyl alcohol dehydrogenase C; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
P48523 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Arabidopsis thaliana (see 3 papers)
    43% identity, 97% coverage of query (238 bits)

F6L7F4 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Camellia sinensis (see paper)
    41% identity, 98% coverage of query (238 bits)

D7PGW0 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Triticum aestivum (see paper)
    44% identity, 94% coverage of query (236 bits)

A0A2Z5D8A5 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Artemisia annua (see paper)
    41% identity, 97% coverage of query (236 bits)

5fi3A / A0A0F6SD02 Heteroyohimbine synthase thas1 from catharanthus roseus - complex with NADP+ (see paper)
    40% identity, 98% coverage of query (236 bits)

5h81B / A0A1C7D193 Heteroyohimbine synthase thas2 from catharanthus roseus - complex with NADP+ (see paper)
    40% identity, 94% coverage of query (234 bits)

5h83A / A0A1C7D195 Heteroyohimbine synthase hys from catharanthus roseus - apo form (see paper)
    42% identity, 94% coverage of query (233 bits)

T1WW82 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    43% identity, 98% coverage of query (231 bits)

I1HY48 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Brachypodium distachyon (see paper)
    45% identity, 94% coverage of query (226 bits)

CAD5 / O49482 cinnamyl alcohol dehydrogenase 5 (EC 1.1.1.195) from Arabidopsis thaliana (see 3 papers)
CADH5_ARATH / O49482 Cinnamyl alcohol dehydrogenase 5; AtCAD5; Cinnamyl alcohol dehydrogenase D; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
O49482 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Arabidopsis thaliana (see 2 papers)
    43% identity, 96% coverage of query (223 bits)

2cf5A / O49482 Crystal structures of the arabidopsis cinnamyl alcohol dehydrogenases, atcad5 (see paper)
    43% identity, 96% coverage of query (223 bits)

2cf6A Crystal structures of the arabidopsis cinnamyl alcohol dehydrogenases atcad5
    43% identity, 96% coverage of query (223 bits)

CADH2_ORYSJ / Q6ZHS4 Cinnamyl alcohol dehydrogenase 2; OsCAD2; Protein GOLD HULL AND INTERNODE 2; EC 1.1.1.195 from Oryza sativa subsp. japonica (Rice) (see 3 papers)
Q6ZHS4 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Oryza sativa Japonica Group (see paper)
    43% identity, 97% coverage of query (221 bits)

RR4 / A0A0U3S9Q3 vomilenine 19,20-reductase from Rauvolfia serpentina (see paper)
    41% identity, 99% coverage of query (220 bits)

DPAS / A0A1B1FHP3 dehydroprecondylocarpine acetate synthase from Catharanthus roseus (see 2 papers)
DPAS_CATRO / A0A1B1FHP3 Dehydroprecondylocarpine acetate synthase; EC 1.1.1.- from Catharanthus roseus (Madagascar periwinkle) (Vinca rosea) (see paper)
    41% identity, 96% coverage of query (216 bits)

A1ILL4 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Sorghum bicolor (see 2 papers)
    43% identity, 98% coverage of query (216 bits)

CADH_MAIZE / O24562 Probable cinnamyl alcohol dehydrogenase; CAD; Brown-midrib 1 protein; EC 1.1.1.195 from Zea mays (Maize) (see paper)
    44% identity, 98% coverage of query (214 bits)

B6U7D8 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Zea mays (see paper)
    44% identity, 98% coverage of query (214 bits)

ADHA_SYNY3 / P74721 Aldehyde reductase AdhA; Alcohol dehydrogenase AdhA; EC 1.1.1.2 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 3 papers)
P74721 alcohol dehydrogenase (EC 1.1.1.1) from Synechocystis sp. PCC 6803 (see paper)
    36% identity, 98% coverage of query (212 bits)

A0A0P0VFU1 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Oryza sativa Japonica Group (see paper)
    45% identity, 88% coverage of query (203 bits)

1lluA / Q9HTD9 The ternary complex of pseudomonas aeruginosa alcohol dehydrogenase with its coenzyme and weak substrate (see paper)
    36% identity, 98% coverage of query (199 bits)

Q8L3C9 alcohol dehydrogenase (EC 1.1.1.1) from Flavobacterium frigidimaris (see paper)
    32% identity, 98% coverage of query (198 bits)

6n7lC / A0A077EGR8 Crystal structure of an alcohol dehydrogenase from elizabethkingia anophelis nuhp1
    35% identity, 98% coverage of query (198 bits)

3s2eA / Q46UZ9 Crystal structure of furx nadh complex 1
    35% identity, 98% coverage of query (197 bits)

furX / Q46UZ9 furfuryl alcohol dehydrogenase (EC 1.1.1.1) from Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (see paper)
    35% identity, 98% coverage of query (197 bits)

3s2fE Crystal structure of furx nadh:furfural
    35% identity, 98% coverage of query (197 bits)

3s2fA Crystal structure of furx nadh:furfural
    35% identity, 98% coverage of query (197 bits)

3s2eE Crystal structure of furx nadh complex 1
    35% identity, 98% coverage of query (197 bits)

RR42_RS34260 Alcohol dehydrogenase (EC 1.1.1.1) from Cupriavidus basilensis FW507-4G11
    34% identity, 98% coverage of query (191 bits)

M4VRJ6 carbonyl reductase (NADPH) (EC 1.1.1.184) from Candida parapsilosis (see paper)
    37% identity, 92% coverage of query (189 bits)

7c2oA / M4VRJ6 Crystal structure of the r-specific carbonyl reductase from candida parapsilosis atcc 7330 without dtt
    37% identity, 92% coverage of query (189 bits)

Q6RS93 alcohol dehydrogenase (EC 1.1.1.1) from Parageobacillus thermoglucosidasius (see paper)
    35% identity, 97% coverage of query (186 bits)

Ahr / b4269 NADPH-dependent aldehyde reductase Ahr (EC 1.1.1.2) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
ahr / P27250 NADPH-dependent aldehyde reductase Ahr (EC 1.1.1.2) from Escherichia coli (strain K12) (see 11 papers)
AHR_ECOLI / P27250 Aldehyde reductase Ahr; Zinc-dependent alcohol dehydrogenase Ahr; EC 1.1.1.2 from Escherichia coli (strain K12) (see 3 papers)
P27250 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Escherichia coli (see paper)
    35% identity, 97% coverage of query (186 bits)

7bu2B / P27250 Structure of alcohol dehydrogenase yjgb from escherichia coli (see paper)
    35% identity, 97% coverage of query (186 bits)

7bu3A Structure of alcohol dehydrogenase yjgb in complex with NADP from escherichia coli
    35% identity, 97% coverage of query (186 bits)

3meqA / A0A0H3G9R2 Crystal structure of alcohol dehydrogenase from brucella melitensis
    32% identity, 98% coverage of query (184 bits)

6iqdA / P42327 Crystal structure of alcohol dehydrogenase from geobacillus stearothermophilus (see paper)
    34% identity, 97% coverage of query (183 bits)

ADH5 / P38113 alcohol dehydrogenase V (EC 1.1.1.1; EC 1.1.1.190) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 10 papers)
ADH5_YEAST / P38113 Alcohol dehydrogenase 5; Alcohol dehydrogenase V; EC 1.1.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
    33% identity, 98% coverage of query (183 bits)

6c49A / A0A1E3MC83 Crystal structure of alcohol dehydrogenase from acinetobacter baumannii
    36% identity, 97% coverage of query (181 bits)

P42328 alcohol dehydrogenase (EC 1.1.1.1) from Geobacillus stearothermophilus (see 8 papers)
1rjwA / P42328 Crystal structure of NAD(+)-dependent alcohol dehydrogenase from bacillus stearothermophilus strain lld-r (see paper)
    34% identity, 99% coverage of query (181 bits)

W6CX26 alcohol dehydrogenase (EC 1.1.1.1); aryl-alcohol dehydrogenase (EC 1.1.1.90); aryl-alcohol dehydrogenase (NADP+) (EC 1.1.1.91) from Yokenella sp. (see paper)
    36% identity, 97% coverage of query (181 bits)

3piiA Crystal structure of mutant of ht- alcohol dehydrogenase with substrate analogue butyramide
    34% identity, 97% coverage of query (180 bits)

6z42A / E1V3M3 The low resolution structure of a zinc-dependent alcohol dehydrogenase from halomonas elongata.
    33% identity, 98% coverage of query (178 bits)

A1IIA3 alcohol dehydrogenase (EC 1.1.1.1) from Kluyveromyces marxianus (see paper)
    33% identity, 99% coverage of query (178 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory