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Searching for up to 100 curated homologs for 14539 FitnessBrowser__Keio:14539 (439 a.a.)

Found high-coverage hits (≥70%) to 11 curated proteins.

Removed hits that are identical to the query, leaving 10

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

BRNQ_SALTY / P0A1W8 Branched-chain amino acid permease BrnQ; BCAA permease; Branched-chain amino acid transport system 2 carrier protein; LIV-II from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    95% identity, 100% coverage of query (828 bits)

TC 2.A.26.1.2 / P25185 Ile/Val:H+ symporter from Pseudomonas aeruginosa (see 2 papers)
    67% identity, 99% coverage of query (583 bits)

TC 2.A.26.1.1 / P19072 Branched chain amino acid: Na+ symporter from Pseudomonas aeruginosa (see 2 papers)
    55% identity, 98% coverage of query (472 bits)

BRAB_BACSU / O34545 Branched-chain amino acid permease BraB; BCAA permease; Branched-chain amino acid transport system carrier protein BraB; Branched-chain amino acid uptake carrier BraB from Bacillus subtilis (strain 168) (see 2 papers)
    42% identity, 96% coverage of query (311 bits)

BRNQ_BACSU / P94499 Branched-chain amino acid permease BrnQ; BCAA permease; Branched-chain amino acid transport system carrier protein BrnQ; Branched-chain amino acid uptake carrier BrnQ from Bacillus subtilis (strain 168) (see paper)
    40% identity, 95% coverage of query (303 bits)

TC 2.A.26.1.9 / F2HK99 Branched chain amino acid (Leucine, Isoleucine, Valine) transporter of 456 aas and 12 TMSs, BrnQ from Lactococcus lactis subsp. lactis (strain CV56)
    36% identity, 95% coverage of query (225 bits)

BRNQ_LACLM / A2RJ04 Branched-chain amino acid permease BrnQ; BCAA permease; Branched-chain amino acid transport system carrier protein from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
    36% identity, 95% coverage of query (222 bits)

BRNQ_LACDL / P54104 Branched-chain amino acid permease BrnQ; BCAA permease; Branched-chain amino acid transport system carrier protein; Branched-chain amino acid uptake carrier from Lactobacillus delbrueckii subsp. lactis (see paper)
TC 2.A.26.1.3 / P54104 Branched chain amino acid:H+ symporter from Lactobacillus delbrueckii (subsp. lactis) (see paper)
brnQ / CAA88595.1 branched-chain amino acid carrier from Lactobacillus delbrueckii (see paper)
    33% identity, 97% coverage of query (217 bits)

BRNQ_CORGL / O06754 Branched-chain amino acid permease BrnQ; BCAA permease; Branched-chain amino acid transport system carrier protein; Branched-chain amino acid uptake carrier from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
    32% identity, 99% coverage of query (199 bits)

Build an alignment

Build an alignment for 14539 and 9 homologs with ≥ 30% identity

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Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Additional hits (identity < 30%)

TC 2.A.26.1.4 / O84558 The branched chain amino acid transporter BrnQ (transports Leu, Ile, Val, Phe, and Met) from Chlamydia trachomatis (see paper)
    28% identity, 83% coverage of query (103 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory