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Searching for up to 100 curated homologs for 14732 FitnessBrowser__Keio:14732 (248 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

Removed hits that are identical to the query, leaving 99

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

8sbzA / A0A0H3FXS4 Crystal structure of 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase from klebsiella aerogenes (NAD bound, no sulfate hexagonal form)
    88% identity, 100% coverage of query (433 bits)

8u9aA / A0A0H3FXS4 Crystal structure of 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase from klebsiella aerogenes (dbh bound)
    78% identity, 100% coverage of query (372 bits)

8sbvB Crystal structure of 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase from klebsiella aerogenes (adp bound)
    75% identity, 100% coverage of query (355 bits)

dhbA / P39071 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (EC 1.3.1.28) from Bacillus subtilis (strain 168) (see 2 papers)
    42% identity, 99% coverage of query (187 bits)

vibA / Q56632 vibriobactin-specific 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (EC 1.3.1.28) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see paper)
    39% identity, 99% coverage of query (180 bits)

6t77A / W9B6I8 Crystal structure of klebsiella pneumoniae fabg(NADPH-dependent) NADP- complex at 1.75 a resolution (see paper)
    35% identity, 98% coverage of query (129 bits)

FabG / b1093 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
fabG / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli (strain K12) (see 22 papers)
FABG_ECOLI / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Escherichia coli (strain K12) (see 9 papers)
P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Escherichia coli (see 2 papers)
    36% identity, 98% coverage of query (128 bits)

FABG_SALTY / P0A2C9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    36% identity, 98% coverage of query (127 bits)

1q7bA The structure of betaketoacyl-[acp] reductase from e. Coli in complex with NADP+
    36% identity, 98% coverage of query (126 bits)

Q2FZ53 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Staphylococcus aureus (see paper)
    34% identity, 96% coverage of query (124 bits)

FABG_STAAM / P0A0H9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Staphylococcus aureus (strain Mu50 / ATCC 700699)
3osuA / P0A0H9 Crystal structure of the 3-oxoacyl-acyl carrier protein reductase, fabg, from staphylococcus aureus
    34% identity, 96% coverage of query (124 bits)

1q7cA The structure of betaketoacyl-[acp] reductase y151f mutant in complex with NADPH fragment
    36% identity, 98% coverage of query (124 bits)

DHRS6_RAT / D4A1J4 Dehydrogenase/reductase SDR family member 6; (R)-beta-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase type 2; 4-oxo-L-proline reductase; Oxidoreductase UCPA; Short chain dehydrogenase/reductase family 15C member 1; EC 1.1.1.-; EC 1.1.1.30; EC 1.1.1.104 from Rattus norvegicus (Rat) (see paper)
    33% identity, 98% coverage of query (122 bits)

3sj7A Structure of beta-ketoacetyl-coa reductase (fabg) from staphylococcus aureus complex with NADPH
    34% identity, 96% coverage of query (120 bits)

Q1J2J0 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Deinococcus geothermalis (see paper)
    35% identity, 98% coverage of query (119 bits)

FABG_AQUAE / O67610 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Aquifex aeolicus (strain VF5)
    33% identity, 98% coverage of query (119 bits)

tpdE / M1WXK8 aminoalcohol dehydrogenase from Rhodococcus sp. TMP1 (see paper)
tpdE / CCN27364.1 aminoalcohol dehydrogenase from Rhodococcus sp. TMP1 (see paper)
    32% identity, 100% coverage of query (119 bits)

4nbtA / A9NFJ2 Crystal structure of fabg from acholeplasma laidlawii (see paper)
    33% identity, 98% coverage of query (118 bits)

DHRS6_MOUSE / Q8JZV9 Dehydrogenase/reductase SDR family member 6; (R)-beta-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase type 2; 4-oxo-L-proline reductase; Oxidoreductase UCPA; Short chain dehydrogenase/reductase family 15C member 1; EC 1.1.1.-; EC 1.1.1.30; EC 1.1.1.104 from Mus musculus (Mouse) (see 3 papers)
Q8JZV9 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Mus musculus (see paper)
    31% identity, 98% coverage of query (118 bits)

RUMGNA_02133 / A7B3K3 chenodeoxycholate 3α-dehydrogenase (EC 1.1.1.392) from Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9) (see 4 papers)
3AHDP_RUMGV / A7B3K3 3alpha-hydroxysteroid dehydrogenase; 3alpha-HSDH; 3alpha-hydroxycholanate dehydrogenase (NADP(+)); NADP-dependent bile acid 3alpha-dehydrogenase; EC 1.1.1.-; EC 1.1.1.392 from Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9) (see paper)
    34% identity, 98% coverage of query (117 bits)

DCXR_CAEEL / Q21929 L-xylulose reductase; XR; Dicarbonyl/L-xylulose reductase; DCXR; Short-chain dehydrogenase 21; EC 1.1.1.10 from Caenorhabditis elegans (see 2 papers)
Q21929 L-xylulose reductase (EC 1.1.1.10) from Caenorhabditis elegans (see paper)
    33% identity, 98% coverage of query (116 bits)

YfeF / b2426 oxidoreductase UcpA (EC 1.1.1.304) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
ucpA / P37440 oxidoreductase UcpA (EC 1.1.1.304) from Escherichia coli (strain K12) (see 6 papers)
    32% identity, 98% coverage of query (116 bits)

7emgB / A0A0G8B235 Carbonyl reductase variant 4 (r123c/l209p/f183y/v61k) from serratia marcescens complexed with NADP+ (see paper)
    34% identity, 97% coverage of query (116 bits)

BPHYT_RS34215 2-keto-3-deoxy-L-fuconate 4-dehydrogenase FucDH from Burkholderia phytofirmans PsJN
    32% identity, 97% coverage of query (112 bits)

1xhlA / Q19774 Crystal structure of putative tropinone reductase-ii from caenorhabditis elegans with cofactor and substrate
    35% identity, 98% coverage of query (112 bits)

1xhlB Crystal structure of putative tropinone reductase-ii from caenorhabditis elegans with cofactor and substrate
    35% identity, 98% coverage of query (112 bits)

GOLD_LISIN / Q92EU6 NAD-dependent glycerol dehydrogenase; Dha-forming NAD-dependent glycerol dehydrogenase; EC 1.1.1.6 from Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262) (see paper)
    30% identity, 96% coverage of query (110 bits)

lra1 / C1DMX5 NAD(P)+-dependent L-rhamnose 1-dehydrogenase (EC 1.1.1.378; EC 1.1.1.173) from Azotobacter vinelandii (strain DJ / ATCC BAA-1303) (see paper)
    33% identity, 96% coverage of query (110 bits)

7b81A / C1DMX5 Crystal structure of azotobacter vinelandii l-rhamnose 1-dehydrogenase (NAD bound-form) (see paper)
    33% identity, 96% coverage of query (110 bits)

7do7A Crystal structure of azotobacter vinelandii l-rhamnose 1- dehydrogenase(NAD and l-rhamnose bound-form)
    33% identity, 96% coverage of query (110 bits)

2ag5A / Q9BUT1 Crystal structure of human dhrs6 (see paper)
    33% identity, 99% coverage of query (109 bits)

Q9HK51 aldose 1-dehydrogenase (NAD+) (EC 1.1.1.121) from Thermoplasma acidophilum (see 2 papers)
    34% identity, 100% coverage of query (109 bits)

baiA3 / P07914 3α-hydroxysteroyl-CoA 3-dehydrogenase monomer (EC 1.1.1.395) from Clostridium scindens (strain JCM 10418 / VPI 12708) (see 8 papers)
BAIA1_CLOSV / P07914 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 1/3; 3alpha-hydroxysteroid dehydrogenase 1/3; 3alpha-HSDH 1/3; Bile acid-inducible protein BaiA1; Bile acid-inducible protein BaiA3; EC 1.1.1.395 from Clostridium scindens (strain JCM 10418 / VPI 12708) (see paper)
    34% identity, 96% coverage of query (109 bits)

BBSD_THAAR / Q9KJF1 (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA dehydrogenase subunit BbsD; (S,R)-2-(alpha-hydroxybenzyl)succinyl-CoA dehydrogenase subunit BbsD; EC 1.1.1.429 from Thauera aromatica (see 2 papers)
    32% identity, 99% coverage of query (109 bits)

dthD / A0QYC2 D-threitol dehydrogenase (EC 1.1.1.403) from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (see paper)
DTHD_MYCS2 / A0QYC2 D-threitol dehydrogenase; EC 1.1.1.403 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
A0QYC2 D-threitol dehydrogenase (NAD+) (EC 1.1.1.403) from Mycolicibacterium smegmatis (see paper)
    38% identity, 72% coverage of query (109 bits)

2dteA / Q9HK51 Structure of thermoplasma acidophilum aldohexose dehydrogenase (aldt) in complex with nadh (see paper)
    34% identity, 100% coverage of query (109 bits)

2dtxA Structure of thermoplasma acidophilum aldohexose dehydrogenase (aldt) in complex with d-mannose
    34% identity, 100% coverage of query (109 bits)

7pcsB / Q9KJF1 Structure of the heterotetrameric sdr family member bbscd (see paper)
    33% identity, 96% coverage of query (108 bits)

4nbuB Crystal structure of fabg from bacillus sp (see paper)
    30% identity, 94% coverage of query (108 bits)

3op4A Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from vibrio cholerae o1 biovar eltor str. N16961 in complex with NADP+ (see paper)
    31% identity, 98% coverage of query (108 bits)

Q4UN54 acetoacetyl-CoA reductase (EC 1.1.1.36) from Rickettsia felis (see paper)
    30% identity, 96% coverage of query (108 bits)

SDH_CERSP / Q59787 Sorbitol dehydrogenase; SDH; Galactitol 2-dehydrogenase; L-iditol 2-dehydrogenase; Polyol dehydrogenase; EC 1.1.1.-; EC 1.1.1.16; EC 1.1.1.14 from Cereibacter sphaeroides (Rhodobacter sphaeroides) (see 2 papers)
polS / GI|2338763 L-iditol 2-dehydrogenase; EC 1.1.1.14 from Rhodobacter sphaeroides (see 2 papers)
    32% identity, 98% coverage of query (108 bits)

Build an alignment

Build an alignment for 14732 and 42 homologs with ≥ 30% identity

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Change minimum %identity:

Additional hits (identity < 30%)

5itvA / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
    29% identity, 99% coverage of query (108 bits)

bacC / P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (strain 168) (see paper)
BACC_BACSU / P39640 Dihydroanticapsin 7-dehydrogenase; Bacilysin biosynthesis oxidoreductase BacC; EC 1.1.1.385 from Bacillus subtilis (strain 168) (see 3 papers)
P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (see paper)
    29% identity, 99% coverage of query (108 bits)

Q9Y8Y1 carbonyl reductase (NADPH) (EC 1.1.1.184) from Aeropyrum pernix (see paper)
    32% identity, 88% coverage of query (108 bits)

swb2 / D2KTX1 3-hydroxykynurenate reductase/dehydratase from Streptomyces sp. SNA15896 (see paper)
    34% identity, 99% coverage of query (107 bits)

BDH2 / Q9BUT1 3-hydroxybutyrate dehydrogenase type 2 (EC 1.1.1.104) from Homo sapiens (see paper)
DHRS6_HUMAN / Q9BUT1 Dehydrogenase/reductase SDR family member 6; (R)-beta-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase type 2; 4-oxo-L-proline reductase; Oxidoreductase UCPA; Short chain dehydrogenase/reductase family 15C member 1; EC 1.1.1.-; EC 1.1.1.30; EC 1.1.1.104 from Homo sapiens (Human) (see 3 papers)
    32% identity, 98% coverage of query (107 bits)

zgc:113054 / Q5BLE6 gadusol synthase from Danio rerio (see 2 papers)
    30% identity, 99% coverage of query (107 bits)

A0A5P1RES5 acetoacetyl-CoA reductase (subunit 1/2) (EC 1.1.1.36) from Neptunomonas concharum (see paper)
    30% identity, 96% coverage of query (106 bits)

FABG_RICPR / P50941 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Rickettsia prowazekii (strain Madrid E)
P50941 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Rickettsia prowazekii (see paper)
    30% identity, 98% coverage of query (106 bits)

PS417_11520 Sorbitol dehydrogenase (EC 1.1.1.14) from Pseudomonas simiae WCS417
    31% identity, 98% coverage of query (106 bits)

ltxD / Q5V8A5 lyngbyatoxin A monooxygenase from Lyngbya majuscula (see 3 papers)
    33% identity, 97% coverage of query (106 bits)

Q86RB1 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Plasmodium falciparum (see paper)
    28% identity, 97% coverage of query (106 bits)

fabG / P51831 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Bacillus subtilis (strain 168) (see 3 papers)
    28% identity, 98% coverage of query (105 bits)

4jroC / Q8Y690 Crystal structure of 3-oxoacyl-[acyl-carrier protein]reductase (fabg) from listeria monocytogenes in complex with NADP+
    31% identity, 99% coverage of query (105 bits)

DHRS6_DANRE / Q561X9 Dehydrogenase/reductase SDR family member 6; (R)-beta-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase type 2; 4-oxo-L-proline reductase; Oxidoreductase UCPA; Short chain dehydrogenase/reductase family 15C member 1; EC 1.1.1.-; EC 1.1.1.30; EC 1.1.1.104 from Danio rerio (Zebrafish) (Brachydanio rerio) (see paper)
Q561X9 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Danio rerio (see paper)
    29% identity, 97% coverage of query (105 bits)

LINX_SPHIU / D4Z260 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase LinX; 2,5-DDOL dehydrogenase; EC 1.1.1.- from Sphingobium indicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S) (Sphingobium japonicum) (see paper)
    32% identity, 99% coverage of query (105 bits)

baiA2 / P19337 3α-hydroxysteroid dehydrogenase 2 (EC 1.1.1.395) from Clostridium scindens (strain JCM 10418 / VPI 12708) (see 4 papers)
BAIA2_CLOSV / P19337 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2; 3alpha-hydroxysteroid dehydrogenase 2; 3alpha-HSDH 2; Bile acid-inducible protein BaiA2; EC 1.1.1.395 from Clostridium scindens (strain JCM 10418 / VPI 12708) (see paper)
P19337 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase (EC 1.1.1.395) from [Clostridium] scindens (see paper)
    32% identity, 96% coverage of query (105 bits)

Q5SLC4 aldose 1-dehydrogenase (NAD+) (EC 1.1.1.121) from Thermus thermophilus (see paper)
    33% identity, 98% coverage of query (105 bits)

5u9pB / B4EEX4 Crystal structure of a gluconate 5-dehydrogenase from burkholderia cenocepacia j2315 in complex with NADP and tartrate
    29% identity, 98% coverage of query (105 bits)

4i08A Crystal structure of beta-ketoacyl-acyl carrier protein reductase (fabg) from vibrio cholerae in complex with NADPH
    30% identity, 98% coverage of query (105 bits)

4is3C / P19337 Crystal structure of a 3alpha-hydroxysteroid dehydrogenase (baia2) associated with secondary bile acid synthesis from clostridium scindens vpi12708 in complex with a putative NAD(+)-oh- adduct at 2.0 a resolution
    32% identity, 96% coverage of query (104 bits)

C0IR58 aryl-alcohol dehydrogenase (NADP+) (EC 1.1.1.91) from Ralstonia sp. (see paper)
4bmsF / C0IR58 Short chain alcohol dehydrogenase from ralstonia sp. Dsm 6428 in complex with NADPH
    31% identity, 97% coverage of query (103 bits)

5ojiA Crystal structure of the dehydrogenase/reductase sdr family member 4 (dhrs4) from caenorhabditis elegans
    30% identity, 97% coverage of query (103 bits)

DHRS4_CAEEL / G5EGA6 Dehydrogenase/reductase SDR family member 4; EC 1.1.1.184 from Caenorhabditis elegans (see paper)
5ojgA / G5EGA6 Crystal structure of the dehydrogenase/reductase sdr family member 4 (dhrs4) from caenorhabditis elegans (see paper)
    30% identity, 97% coverage of query (103 bits)

FABG_SYNY3 / P73574 3-oxoacyl-[acyl-carrier-protein] reductase; 3-ketoacyl-acyl carrier protein reductase; EC 1.1.1.100 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
    36% identity, 96% coverage of query (103 bits)

3uxyC / Q3IVH6 The crystal structure of short chain dehydrogenase from rhodobacter sphaeroides
    35% identity, 71% coverage of query (103 bits)

1vl8B / Q9WYS2 Crystal structure of gluconate 5-dehydrogenase (tm0441) from thermotoga maritima at 2.07 a resolution
    28% identity, 99% coverage of query (103 bits)

5t2uA / A0R723 Short chain dehydrogenase/reductase family protein (see paper)
    35% identity, 98% coverage of query (103 bits)

7do6A Crystal structure of azotobacter vinelandii l-rhamnose 1- dehydrogenase(NADP bound-form)
    32% identity, 96% coverage of query (102 bits)

6ihhA Crystal structure of rasadh f12 from ralstonia.Sp in complex with NADPH and a6o
    30% identity, 97% coverage of query (102 bits)

4dmmB / Q31QF3 3-oxoacyl-[acyl-carrier-protein] reductase from synechococcus elongatus pcc 7942 in complex with NADP
    33% identity, 94% coverage of query (102 bits)

5b1yB / Q9Y8Y1 Crystal structure of NADPH bound carbonyl reductase from aeropyrum pernix (see paper)
    31% identity, 88% coverage of query (102 bits)

7krmC / A0A077GFB1 Putative fabg bound to nadh from acinetobacter baumannii
    31% identity, 98% coverage of query (102 bits)

1nfqA Rv2002 gene product from mycobacterium tuberculosis
    30% identity, 99% coverage of query (102 bits)

1nffA / P9WGT1 Crystal structure of rv2002 gene product from mycobacterium tuberculosis (see paper)
    30% identity, 99% coverage of query (102 bits)

budC / H9XP47 meso-butanediol dehydrogenase [(R)-acetoin-forming] (EC 1.1.1.304; EC 1.1.1.76) from Serratia marcescens (see paper)
MBDH_SERMA / H9XP47 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens (see 3 papers)
    32% identity, 99% coverage of query (102 bits)

3uf0A / C5BY10 Crystal structure of a putative NAD(p) dependent gluconate 5- dehydrogenase from beutenbergia cavernae(efi target efi-502044) with bound NADP (low occupancy)
    33% identity, 97% coverage of query (101 bits)

5ovlA Crystal structure of maba bound to NADP+ from m. Smegmatis
    31% identity, 99% coverage of query (101 bits)

MABA_MYCS2 / P71534 3-oxoacyl-[acyl-carrier-protein] reductase MabA; 3-ketoacyl-acyl carrier protein reductase; Acetoacetyl-CoA reductase; Beta-ketoacyl-ACP reductase; Beta-ketoacyl-acyl carrier protein reductase; EC 1.1.1.100; EC 1.1.1.36 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
P71534 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Mycolicibacterium smegmatis (see paper)
    31% identity, 99% coverage of query (101 bits)

HSD_MYCTU / P9WGT1 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; NADH-dependent 3alpha, 20beta-hydroxysteroid dehydrogenase; EC 1.1.1.53 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
GI|3261591 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; EC 1.1.1.53 from Mycobacterium tuberculosis H37Rv (see paper)
    31% identity, 98% coverage of query (100 bits)

5ovkA / P71534 Crystal structure maba bound to NADPH from m. Smegmatis (see paper)
    31% identity, 99% coverage of query (100 bits)

3o4rA / Q9BTZ2 Crystal structure of human dehydrogenase/reductase (sdr family) member 4 (dhrs4)
    31% identity, 98% coverage of query (100 bits)

6xewA Structure of serratia marcescens 2,3-butanediol dehydrogenase
    32% identity, 98% coverage of query (100 bits)

6vspA Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a
    32% identity, 98% coverage of query (100 bits)

DHRS4_HUMAN / Q9BTZ2 Dehydrogenase/reductase SDR family member 4; NADPH-dependent carbonyl reductase; CR; NADPH-dependent retinol dehydrogenase/reductase; NRDR; humNRDR; Peroxisomal short-chain alcohol dehydrogenase; PSCD; SCAD-SRL; Short chain dehydrogenase/reductase family 25C member 2; Protein SDR25C2; Short-chain dehydrogenase/reductase family member 4; EC 1.1.1.184 from Homo sapiens (Human) (see 7 papers)
Q9BTZ2 NADP-retinol dehydrogenase (EC 1.1.1.300) from Homo sapiens (see paper)
    31% identity, 98% coverage of query (100 bits)

1cydA / P08074 Carbonyl reductase complexed with NADPH and 2-propanol (see paper)
    32% identity, 98% coverage of query (100 bits)

2d1yA Crystal structure of tt0321 from thermus thermophilus hb8
    32% identity, 98% coverage of query (100 bits)

CBR2_MOUSE / P08074 Carbonyl reductase [NADPH] 2; Adipocyte protein P27; AP27; Lung carbonyl reductase; LCR; NADPH-dependent carbonyl reductase 2; EC 1.1.1.184 from Mus musculus (Mouse) (see 3 papers)
    32% identity, 98% coverage of query (100 bits)

6vspB / H9XP47 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a (see paper)
    32% identity, 98% coverage of query (100 bits)

8bcjB / Q9HZ96 Crystal structure of short-chain dehydrogenase pa3128 from pseudomonas aeruginosa pao1 in complex with NADP+
    36% identity, 96% coverage of query (100 bits)

xecD / Q56840 2-(R)-hydroxypropyl-CoM dehydrogenase subunit (EC 1.1.1.268) from Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) (see 5 papers)
HCDR1_XANP2 / Q56840 2-(R)-hydroxypropyl-CoM dehydrogenase; R-HPCDH; 2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase; Aliphatic epoxide carboxylation component III; Epoxide carboxylase component III; RHPCDH1; EC 1.1.1.268 from Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) (see 7 papers)
Q56840 2-(R)-hydroxypropyl-CoM dehydrogenase (EC 1.1.1.268) from Xanthobacter autotrophicus (see 4 papers)
2cfcA / Q56840 Structural basis for stereo selectivity in the (r)- and (s)-hydroxypropylethane thiosulfonate dehydrogenases (see paper)
    33% identity, 95% coverage of query (99.8 bits)

3ak4A / G1K3P5 Crystal structure of nadh-dependent quinuclidinone reductase from agrobacterium tumefaciens
    35% identity, 98% coverage of query (99.4 bits)

3toxA / Q92SS3 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021
    33% identity, 98% coverage of query (99.4 bits)

1uznA / P9WGT3 Maba from mycobacterium tuberculosis (see paper)
    31% identity, 99% coverage of query (99.4 bits)

4k6fB / B4EAU4 X-ray crystal structure of a putative acetoacetyl-coa reductase from burkholderia cenocepacia bound to the co-factor NADP
    28% identity, 96% coverage of query (99.0 bits)

5fffA Noroxomaritidine/norcraugsodine reductase in complex with NADP+ and piperonal
    28% identity, 98% coverage of query (98.6 bits)

NR_NARAP / A0A1C9II22 Noroxomaritidine/norcraugsodine reductase; NorRed; EC 1.1.1.- from Narcissus aff. pseudonarcissus MK-2014 (Daffodil) (see paper)
NR_NARPS / A0A1A9TAK5 Noroxomaritidine/norcraugsodine reductase; NorRed; EC 1.1.1.- from Narcissus pseudonarcissus (Daffodil) (see 2 papers)
5ff9B / A0A1A9TAK5 Noroxomaritidine/norcraugsodine reductase in complex with NADP+ and tyramine (see paper)
    28% identity, 98% coverage of query (98.6 bits)

fabG1 / P9WGT2 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) (see paper)
MABA_MYCTU / P9WGT3 3-oxoacyl-[acyl-carrier-protein] reductase MabA; 3-ketoacyl reductase; 3-ketoacyl-acyl carrier protein reductase; Acetoacetyl-CoA reductase; Beta-ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; Mycolic acid biosynthesis A; EC 1.1.1.100; EC 1.1.1.36 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 10 papers)
P9WGT3 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Mycobacterium tuberculosis (see paper)
    31% identity, 99% coverage of query (98.2 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory