Searching for up to 100 curated homologs for 14749 FitnessBrowser__Keio:14749 (487 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

Removed hits that are identical to the query, leaving 17

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

YgjC / b3063 L-tartrate:succinate antiporter from Escherichia coli K-12 substr. MG1655
ttdT / P39414 L-tartrate:succinate antiporter from Escherichia coli (strain K12) (see 5 papers)
TTDT_ECOLI / P39414 L-tartrate/succinate antiporter; Tartrate carrier; Tartrate transporter from Escherichia coli (strain K12) (see 3 papers)
TC 2.A.47.3.3 / P39414 L-tartrate:succinate antiporter, TtdT (YgjE). (also takes up meso and L-tartrate and succinate; does not transport D-tartrate) from Escherichia coli (see 8 papers)
ttdT / RF|NP_417535 L-tartrate/succinate antiporter from Escherichia coli K12 (see 8 papers)
    45% identity, 97% coverage of query (438 bits)

DIT21_ARATH / Q9FMF7 Dicarboxylate transporter 2.1, chloroplastic; AtpDCT1; Glutamate/malate translocator from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    35% identity, 92% coverage of query (262 bits)

TC 2.A.47.3.4 / Q6D017 The pmf-dependent citrate uptake system, Cit1 from Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum) (see paper)
    34% identity, 95% coverage of query (259 bits)

YbhI / b0770 putative tricarboxylate transporter from Escherichia coli K-12 substr. MG1655 (see 3 papers)
    33% identity, 100% coverage of query (258 bits)

DIT2_SPIOL / Q8L7Z9 Dicarboxylate transporter 2, chloroplastic; Glutamate/malate translocator from Spinacia oleracea (Spinach) (see paper)
    34% identity, 95% coverage of query (257 bits)

DIT22_ARATH / Q9FMF8 Dicarboxylate transporter 2.2, chloroplastic; AtpDCT2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    33% identity, 93% coverage of query (246 bits)

DIT1_SPIOL / Q41364 Dicarboxylate transporter 1, chloroplastic; SODIT1; 2-oxoglutarate/malate translocator from Spinacia oleracea (Spinach) (see 2 papers)
TC 2.A.47.3.1 / Q41364 2-oxoglutarate:malate antiporter (SodiTl) from Spinacia oleracea (Spinach) (see paper)
SODIT1 2-oxoglutarate/malate translocator from Spinacia oleracea (see paper)
SODiT1 / AAA68148.1 2-oxoglutarate/malate translocator from Spinacia oleracea (see paper)
    34% identity, 99% coverage of query (244 bits)

DIT1_ARATH / Q9LXV3 Dicarboxylate transporter 1, chloroplastic; 2-oxoglutarate/malate translocator 1; AtpOMT1 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    32% identity, 98% coverage of query (239 bits)

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Build an alignment for 14749 and 8 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

TC 2.A.47.1.12 / A4QAL6 The aerobic dicarboxylate (succinate (Km, 30 μM), fumarate (Km, 79 from Corynebacterium glutamicum (strain R) (see paper)
    26% identity, 81% coverage of query (75.9 bits)

TC 2.A.47.1.11 / Q2FFH9 The Na+ (or Li+):dicarboxylate (2:1) symporter, SdcS (catalyzes succinate:succinate antiport as well as electroneutral symport in reconstituted proteoliposomes from Staphylococcus aureus (strain USA300) (see paper)
    22% identity, 75% coverage of query (67.0 bits)

SDCS_STAAM / Q99SX1 Sodium-dependent dicarboxylate transporter SdcS; Na(+)/dicarboxylate symporter from Staphylococcus aureus (strain Mu50 / ATCC 700699) (see 2 papers)
    22% identity, 75% coverage of query (66.2 bits)

VCA0025 / Q9KNE0 dicarboxylate:Na⁺ symporter from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see 6 papers)
TC 2.A.47.5.2 / Q9KNE0 Dicarboxylate (succinate, fumarate, malate) transporter, vcINDY from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
    24% identity, 79% coverage of query (60.8 bits)

7t9gA / Q9KNE0 Structure of vcindy-na+ (see paper)
    24% identity, 79% coverage of query (60.5 bits)

6okzB Structure of vcindy bound to fumarate
    24% identity, 79% coverage of query (60.5 bits)

6wtxA Structure of vcindy in complex with terephthalate
    24% identity, 79% coverage of query (60.5 bits)

TC 2.A.47.1.13 / Q65NC0 The Na+-coupled dicarboxylate (succinate; malate; fumarate) transporter, SdcL (transports aspartate, α-ketoglutarate and oxaloacetate with low affinity). Km for succinate, ~6 from Bacillus licheniformis (strain DSM 13 / ATCC 14580) (see 2 papers)
    23% identity, 79% coverage of query (59.3 bits)

TC 2.A.47.5.1 / Q58086 Hypothetical Na+ cotransporter, Orfl from Methanococcus jannaschii (see paper)
    22% identity, 78% coverage of query (59.3 bits)

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