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Searching for up to 100 curated homologs for 14808 FitnessBrowser__Keio:14808 (266 a.a.)

Found high-coverage hits (≥70%) to 29 curated proteins.

Removed hits that are identical to the query, leaving 25

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

5hj5B / Q9KKS5 Crystal structure of tertiary complex of glucosamine-6-phosphate deaminase from vibrio cholerae with beta-d-glucose-6-phosphate and fructose-6-phosphate
    79% identity, 100% coverage of query (459 bits)

CH_124073 putative glucosamine-6-phosphate deaminase from Magnaporthe grisea 70-15 (see 2 papers)
    60% identity, 97% coverage of query (346 bits)

GNPI1_BOVIN / A4FV08 Glucosamine-6-phosphate isomerase 1; Glucosamine-6-phosphate deaminase 1; GNPDA 1; GlcN6P deaminase 1; Oscillin; EC 3.5.99.6 from Bos taurus (Bovine) (see paper)
    60% identity, 97% coverage of query (338 bits)

GNPI1_MESAU / Q64422 Glucosamine-6-phosphate isomerase 1; Glucosamine-6-phosphate deaminase 1; GNPDA 1; GlcN6P deaminase 1; Oscillin; EC 3.5.99.6 from Mesocricetus auratus (Golden hamster) (see paper)
    60% identity, 97% coverage of query (338 bits)

E1C878 glucosamine-6-phosphate deaminase (EC 3.5.99.6) from Gallus gallus (see paper)
    60% identity, 97% coverage of query (337 bits)

GNPI1_MOUSE / O88958 Glucosamine-6-phosphate isomerase 1; Glucosamine-6-phosphate deaminase 1; GNPDA 1; GlcN6P deaminase 1; Oscillin; EC 3.5.99.6 from Mus musculus (Mouse) (see paper)
    60% identity, 97% coverage of query (335 bits)

GNPI1_HUMAN / P46926 Glucosamine-6-phosphate isomerase 1; Glucosamine-6-phosphate deaminase 1; GNPDA 1; GlcN6P deaminase 1; Oscillin; EC 3.5.99.6 from Homo sapiens (Human) (see 3 papers)
    60% identity, 97% coverage of query (334 bits)

1ne7A / P46926 Human glucosamine-6-phosphate deaminase isomerase at 1.75 a resolution complexed with n-acetyl-glucosamine-6-phosphate and 2-deoxy-2-amino- glucitol-6-phosphate (see paper)
    60% identity, 97% coverage of query (334 bits)

3hn6A / O30564 Crystal structure of glucosamine-6-phosphate deaminase from borrelia burgdorferi
    61% identity, 98% coverage of query (333 bits)

GNPI2_HUMAN / Q8TDQ7 Glucosamine-6-phosphate isomerase 2; Glucosamine-6-phosphate deaminase 2; GNPDA 2; GlcN6P deaminase 2; Glucosamine-6-phosphate isomerase SB52; EC 3.5.99.6 from Homo sapiens (Human) (see 2 papers)
Q8TDQ7 glucosamine-6-phosphate deaminase (EC 3.5.99.6) from Homo sapiens (see 2 papers)
    59% identity, 97% coverage of query (333 bits)

U5LXR4 glucosamine-6-phosphate deaminase (EC 3.5.99.6) from Gallus gallus (see paper)
    61% identity, 71% coverage of query (254 bits)

Shew_0815 Glucosamine-6-phosphate deaminase (EC 3.5.99.6) from Shewanella loihica PV-4
    43% identity, 98% coverage of query (213 bits)

NAGB_STRCO / Q9K487 Glucosamine-6-phosphate deaminase; GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase; EC 3.5.99.6 from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
    45% identity, 86% coverage of query (200 bits)

NAGB_BACSU / O35000 Glucosamine-6-phosphate deaminase 1; GlcN6P deaminase 1; GNPDA 1; Glucosamine-6-phosphate isomerase 1; EC 3.5.99.6 from Bacillus subtilis (strain 168) (see 3 papers)
O35000 glucosamine-6-phosphate deaminase (EC 3.5.99.6) from Bacillus subtilis (see paper)
2bkvB / O35000 Structure and kinetics of a monomeric glucosamine-6-phosphate deaminase: missing link of the nagb superfamily (see paper)
    40% identity, 90% coverage of query (193 bits)

2bkxA Structure and kinetics of a monomeric glucosamine-6-phosphate deaminase: missing link of the nagb superfamily
    40% identity, 90% coverage of query (193 bits)

GAMA_BACSU / O31458 Glucosamine-6-phosphate deaminase 2; GlcN6P deaminase 2; GNPDA 2; Glucosamine-6-phosphate isomerase 2; EC 3.5.99.6 from Bacillus subtilis (strain 168) (see 3 papers)
    37% identity, 93% coverage of query (179 bits)

GPI1 / O97439 glucosamine 6-phosphate isomerase 1 (EC 3.5.99.6) from Giardia intestinalis (see 2 papers)
    42% identity, 74% coverage of query (179 bits)

CA265_RS21925 Glucosamine-6-phosphate deaminase (EC 3.5.99.6) from Pedobacter sp. GW460-11-11-14-LB5
    38% identity, 86% coverage of query (156 bits)

2ri1A / Q8DV70 Crystal structure of glucosamine 6-phosphate deaminase (nagb) with glcn6p from s. Mutans (see paper)
    39% identity, 77% coverage of query (145 bits)

nagB / A3CLX4 glucosamine-6-phosphate deaminase subunit (EC 3.5.99.6) from Streptococcus sanguinis (strain SK36) (see 2 papers)
    34% identity, 93% coverage of query (142 bits)

A8YZR7 glucosamine-6-phosphate deaminase (EC 3.5.99.6) from Staphylococcus aureus (see paper)
    32% identity, 91% coverage of query (135 bits)

Build an alignment

Build an alignment for 14808 and 21 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

YraG / b3141 putative deaminase AgaI from Escherichia coli K-12 substr. MG1655 (see 6 papers)
AGAI_ECOLI / P42912 Putative deaminase AgaI; EC 3.5.99.- from Escherichia coli (strain K12) (see paper)
    28% identity, 88% coverage of query (80.5 bits)

YieK / b3718 putative glucosamine-6-phosphate deaminase YieK from Escherichia coli K-12 substr. MG1655 (see 2 papers)
    26% identity, 89% coverage of query (69.3 bits)

3eb9A Crystal structure of 6-phosphogluconolactonase from trypanosoma brucei complexed with citrate
    24% identity, 76% coverage of query (45.1 bits)

3e7fB / Q9GRG6 Crystal structure of 6-phosphogluconolactonase from trypanosoma brucei complexed with 6-phosphogluconic acid (see paper)
    24% identity, 76% coverage of query (45.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory