Searching for up to 100 curated homologs for 14810 FitnessBrowser__Keio:14810 (554 a.a.)

Found high-coverage hits (≥70%) to 32 curated proteins.

Removed hits that are identical to the query, leaving 30

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

1o0cA Crystal structure of l-glutamate and ampcpp bound to glutamine aminoacyl tRNA synthetase
    98% identity, 97% coverage of query (1102 bits)

1o0bA Crystal structure of l-glutamine and ampcpp bound to glutamine aminoacyl tRNA synthetase
    98% identity, 97% coverage of query (1102 bits)

1gtsA Structural basis for transfer RNA aminoaceylation by escherichia coli glutaminyl-tRNA synthetase
    98% identity, 97% coverage of query (1102 bits)

1exdA Crystal structure of a tight-binding glutamine tRNA bound to glutamine aminoacyl tRNA synthetase
    98% identity, 97% coverage of query (1102 bits)

1euqA Crystal structure of glutaminyl-tRNA synthetase complexed with a tRNA- gln mutant and an active-site inhibitor
    98% identity, 97% coverage of query (1102 bits)

2re8A Glutaminyl-tRNA synthetase mutant c229r with bound analog 5'-o-[n-(l- glutamyl)-sulfamoyl]adenosine
    98% identity, 97% coverage of query (1097 bits)

A0A125YXL3 glutamine-tRNA ligase (EC 6.1.1.18) from Toxoplasma gondii (see paper)
    53% identity, 97% coverage of query (590 bits)

5zdkA / Q5SKU4 Crystal structure analysis of ttqrs in complex with atp (see paper)
    52% identity, 97% coverage of query (540 bits)

glnS / P56926 glutaminyl-tRNA synthetase (EC 6.1.1.18) from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1) (see paper)
    45% identity, 98% coverage of query (514 bits)

SYQ_ARATH / Q8W4F3 Glutamine--tRNA ligase, cytoplasmic; Glutaminyl-tRNA synthetase; GlnRS; Protein OVULE ABORTION 9; EC 6.1.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    47% identity, 98% coverage of query (475 bits)

SYQ_RAT / Q66H61 Glutamine--tRNA ligase; Glutaminyl-tRNA synthetase; GlnRS; EC 6.1.1.18 from Rattus norvegicus (Rat) (see paper)
    47% identity, 95% coverage of query (446 bits)

SYQ_MOUSE / Q8BML9 Glutamine--tRNA ligase; Glutaminyl-tRNA synthetase; GlnRS; EC 6.1.1.18 from Mus musculus (Mouse) (see paper)
    46% identity, 95% coverage of query (442 bits)

SYQ_HUMAN / P47897 Glutamine--tRNA ligase; Glutaminyl-tRNA synthetase; GlnRS; EC 6.1.1.18 from Homo sapiens (Human) (see 6 papers)
P47897 glutamine-tRNA ligase (EC 6.1.1.18) from Homo sapiens (see 4 papers)
    46% identity, 95% coverage of query (441 bits)

4h3sA / P13188 The structure of glutaminyl-tRNA synthetase from saccharomyces cerevisiae (see paper)
    42% identity, 95% coverage of query (409 bits)

SYQ_YEAST / P13188 Glutamine--tRNA ligase; Glutaminyl-tRNA synthetase; GlnRS; EC 6.1.1.18 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P13188 glutamine-tRNA ligase (EC 6.1.1.18); glutaminyl-tRNA synthase (glutamine-hydrolysing) (EC 6.3.5.7) from Saccharomyces cerevisiae (see 2 papers)
    42% identity, 95% coverage of query (409 bits)

SYQ_SCHPO / Q9Y7Y8 Probable glutamine--tRNA ligase; Glutaminyl-tRNA synthetase; GlnRS; EC 6.1.1.18 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    41% identity, 97% coverage of query (403 bits)

VIRJ_HYPVG / G9N4A3 Glutamine--tRNA ligase protein virJ; Trichoxide biosynthesis protein virJ; Virensol biosynthesis cluster protein J; EC 6.1.1.18 from Hypocrea virens (strain Gv29-8 / FGSC 10586) (Gliocladium virens) (Trichoderma virens) (see paper)
    40% identity, 95% coverage of query (344 bits)

SYEC_YEAST / P46655 Glutamate--tRNA ligase, cytoplasmic; Glutamyl-tRNA synthetase; (c)ERS; GluRS; P85; EC 6.1.1.17 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
P46655 glutamate-tRNA ligase (EC 6.1.1.17) from Saccharomyces cerevisiae (see 3 papers)
    36% identity, 94% coverage of query (318 bits)

SYEC_SCHPO / O13775 Probable glutamate--tRNA ligase, cytoplasmic; Glutamyl-tRNA synthetase; GluRS; EC 6.1.1.17 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    36% identity, 93% coverage of query (308 bits)

SYEP_MOUSE / Q8CGC7 Bifunctional glutamate/proline--tRNA ligase; Bifunctional aminoacyl-tRNA synthetase; EC 6.1.1.17; EC 6.1.1.15 from Mus musculus (Mouse) (see 3 papers)
Q8CGC7 proline-tRNA ligase (EC 6.1.1.15); glutamate-tRNA ligase (EC 6.1.1.17) from Mus musculus (see paper)
    36% identity, 92% coverage of query (305 bits)

SYEP_CRIGR / Q7SIA2 Bifunctional glutamate/proline--tRNA ligase; Bifunctional aminoacyl-tRNA synthetase; Glutamyl-prolyl-tRNA synthetase; EC 6.1.1.17; EC 6.1.1.15 from Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (see paper)
    35% identity, 97% coverage of query (303 bits)

SYEP_HUMAN / P07814 Bifunctional glutamate/proline--tRNA ligase; Bifunctional aminoacyl-tRNA synthetase; Cell proliferation-inducing gene 32 protein; Glutamatyl-prolyl-tRNA synthetase; EC 6.1.1.17; EC 6.1.1.15 from Homo sapiens (Human) (see 16 papers)
P07814 proline-tRNA ligase (EC 6.1.1.15); glutamate-tRNA ligase (EC 6.1.1.17) from Homo sapiens (see 3 papers)
    35% identity, 94% coverage of query (301 bits)

SYEC_DICDI / Q54KB8 Probable glutamate--tRNA ligase, cytoplasmic; Glutamyl-tRNA synthetase; GluRS; EC 6.1.1.17 from Dictyostelium discoideum (Social amoeba) (see paper)
    34% identity, 92% coverage of query (293 bits)

SYEC_ARATH / O82462 Glutamate--tRNA ligase, cytoplasmic; GluRSAt; Glutamyl-tRNA synthetase; GluRS; EC 6.1.1.17 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
O82462 glutamate-tRNA ligase (EC 6.1.1.17) from Arabidopsis thaliana (see paper)
    34% identity, 94% coverage of query (286 bits)

SYEP_DROME / P28668 Bifunctional glutamate/proline--tRNA ligase; Bifunctional aminoacyl-tRNA synthetase; EC 6.1.1.17; EC 6.1.1.15 from Drosophila melanogaster (Fruit fly) (see paper)
    35% identity, 93% coverage of query (278 bits)

7waoA / Q8IDK7 Glutamyl-tRNA synthetase from plasmodium falciparum (pfers) in complex with mn (see paper)
    36% identity, 92% coverage of query (266 bits)

7wajA Glutamyl-tRNA synthetase from plasmodium falciparum (pfers) complexed with atp and co
    36% identity, 92% coverage of query (258 bits)

7wakA Glutamyl-tRNA synthetase from plasmodium falciparum (pfers) in complex with adp
    35% identity, 92% coverage of query (251 bits)

O26157 glutamate-tRNA ligase (EC 6.1.1.17) from Methanobacterium thermoautotrophicus (see paper)
gltX / GI|2621087 glutamate--tRNA ligase, non-discriminating; EC 6.1.1.17 from Methanothermobacter thermautotrophicus str. Delta H (see paper)
    30% identity, 92% coverage of query (198 bits)

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Build an alignment for 14810 and 29 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

3aiiA / O26157 Archaeal non-discriminating glutamyl-tRNA synthetase from methanothermobacter thermautotrophicus (see paper)
    29% identity, 92% coverage of query (187 bits)

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