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Searching for up to 100 curated homologs for 14883 FitnessBrowser__Keio:14883 (348 a.a.)

Found high-coverage hits (≥70%) to 24 curated proteins.

Removed hits that are identical to the query, leaving 23

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

1gupA / P09148 Structure of nucleotidyltransferase complexed with udp-galactose (see paper)
    100% identity, 100% coverage of query (726 bits)

1guqA Structure of nucleotidyltransferase complexed with udp-glucose
    100% identity, 100% coverage of query (726 bits)

1hxpA Nucleotide transferase
    98% identity, 100% coverage of query (706 bits)

1hxpB Nucleotide transferase
    95% identity, 99% coverage of query (681 bits)

Q03249 UDP-glucose-hexose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Mus musculus (see 2 papers)
    56% identity, 98% coverage of query (414 bits)

GALT / P07902 galactose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Homo sapiens (see 13 papers)
GALT_HUMAN / P07902 Galactose-1-phosphate uridylyltransferase; Gal-1-P uridylyltransferase; UDP-glucose--hexose-1-phosphate uridylyltransferase; EC 2.7.7.12 from Homo sapiens (Human) (see 28 papers)
P07902 UDP-glucose-hexose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Homo sapiens (see 9 papers)
    57% identity, 98% coverage of query (414 bits)

A2AMS3 UDP-glucose-hexose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Mus musculus (see paper)
    56% identity, 98% coverage of query (414 bits)

P43424 UDP-glucose-hexose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Rattus norvegicus (see paper)
    56% identity, 98% coverage of query (412 bits)

6gqdA / P07902 Structure of human galactose-1-phosphate uridylyltransferase (galt), with crystallization epitope mutations a21y:a22t:t23p:r25l
    56% identity, 98% coverage of query (408 bits)

5in3A Crystal structure of glucose-1-phosphate bound nucleotidylated human galactose-1-phosphate uridylyltransferase
    55% identity, 97% coverage of query (390 bits)

Echvi_0695 UDP-glucose--hexose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Echinicola vietnamensis KMM 6221, DSM 17526
    51% identity, 99% coverage of query (388 bits)

CA265_RS06120 UDP-glucose--hexose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Pedobacter sp. GW460-11-11-14-LB5
    51% identity, 98% coverage of query (371 bits)

GAL7_HYPJE / Q96UI1 Galactose-1-phosphate uridylyltransferase; Gal-1-P uridylyltransferase; UDP-glucose--hexose-1-phosphate uridylyltransferase; EC 2.7.7.12 from Hypocrea jecorina (Trichoderma reesei) (see paper)
    45% identity, 97% coverage of query (332 bits)

M4MCS2 UDP-glucose-hexose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Bifidobacterium bifidum (see paper)
    31% identity, 98% coverage of query (142 bits)

6k5zB / Q8ZXN7 Structure of uridylyltransferase (see paper)
    30% identity, 93% coverage of query (126 bits)

Q8ZXN7 UDP-glucose-hexose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Pyrobaculum aerophilum (see 2 papers)
    30% identity, 93% coverage of query (125 bits)

Build an alignment

Build an alignment for 14883 and 16 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

6k9zA Structure of uridylyltransferase mutant
    28% identity, 93% coverage of query (104 bits)

AGLUP_ARATH / Q9FK51 ADP-glucose phosphorylase; ADP-glucose:phosphate adenylyltransferase; EC 2.7.7.- from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    26% identity, 82% coverage of query (99.4 bits)

UT / Q19TV7 galactose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Cucumis melo (see paper)
    27% identity, 82% coverage of query (95.1 bits)

2h39B / Q9FK51 Crystal structure of an adp-glucose phosphorylase from arabidopsis thaliana with bound adp-glucose
    26% identity, 82% coverage of query (93.6 bits)

1z84A X-ray structure of galt-like protein from arabidopsis thaliana at5g18200
    25% identity, 82% coverage of query (87.8 bits)

apt / Q9LA72 adenylylsulfate:phosphate adenylyltransferase subunit (EC 2.7.7.5) from Thiobacillus denitrificans (see paper)
Q9LA72 sulfate adenylyltransferase (ADP) (EC 2.7.7.5) from Thiobacillus denitrificans (see paper)
    24% identity, 94% coverage of query (83.6 bits)

hygO / Q2MFS4 NDP-heptose synthase from Streptomyces hygroscopicus subsp. hygroscopicus (see paper)
    26% identity, 83% coverage of query (75.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory