Searching for up to 100 curated homologs for 14935 FitnessBrowser__Keio:14935 (219 a.a.)
Found high-coverage hits (≥70%) to 38 curated proteins.
Removed hits that are identical to the query, leaving 37
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TC 3.A.1.3.17 / Q8YSA2 Basic amino acid uptake transporter, BgtAB (see paper)
45% identity, 92% coverage of query (169 bits)
Ac3H11_2554 ABC transporter for L-Histidine, permease component 1 from Acidovorax sp. GW101-3H11
39% identity, 99% coverage of query (156 bits)
TC 3.A.1.3.12 / P73544 BgtB aka GLNH aka SLL1270, component of Arginine/lysine/histidine/glutamine porter (see paper)
48% identity, 74% coverage of query (155 bits)
AO356_00475 ABC transporter for D-Glucosamine, permease component 2 from Pseudomonas fluorescens FW300-N2C3
39% identity, 99% coverage of query (145 bits)
Pf6N2E2_2052 ABC transporter for D-Glucosamine Hydrochloride, permease component 2 from Pseudomonas fluorescens FW300-N2E2
39% identity, 99% coverage of query (145 bits)
4ymtC / Q8RCC3 Crystal structure of an amino acid abc transporter complex with arginines (see paper)
38% identity, 99% coverage of query (143 bits)
AO353_21715 ABC transporter for D-glucosamine, permease component 1 from Pseudomonas fluorescens FW300-N2E3
39% identity, 99% coverage of query (142 bits)
4ymwC Crystal structure of an amino acid abc transporter with histidines
38% identity, 99% coverage of query (142 bits)
TC 3.A.1.3.25 / Q9CES5 Glutamine ABC transporter permease and substrate binding protein protein, component of Glutamine transporter, GlnQP. Takes up glutamine, asparagine and glutamate which compete for each other for binding both substrate and the transmembrane protein constituent of the system (Fulyani et al. 2015). Tandem substrate binding domains (SBDs) differ in substrate specificity and affinity, allowing cells to efficiently accumulate different amino acids via a single ABC transporter. Analysis revealed the roles of individual residues in determining the substrate affinity from Lactococcus lactis subsp. lactis (strain IL1403)
35% identity, 91% coverage of query (139 bits)
TCYL_BACSU / O34315 L-cystine transport system permease protein TcyL from Bacillus subtilis (strain 168) (see 2 papers)
TC 3.A.1.3.13 / O34315 TcyL (YtmL), component of Uptake system for L-cystine (Km=2.5 μM), L-cystathionine, L-djenkolate ( 2-amino-3-[(2-amino-3-hydroxy-3-oxopropyl)sulfanylmethylsulfanyl] propanoic acid), and S-methyl-L-cysteine from Bacillus subtilis (see 4 papers)
35% identity, 98% coverage of query (136 bits)
TcyL / b1918 cystine ABC transporter membrane subunit (EC 7.4.2.12) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
tcyL / P0AFT2 cystine ABC transporter membrane subunit (EC 7.4.2.12) from Escherichia coli (strain K12) (see 3 papers)
TCYL_ECOLI / P0AFT2 L-cystine transport system permease protein TcyL from Escherichia coli (strain K12) (see 5 papers)
TC 3.A.1.3.10 / P0AFT2 Inner membrane amino-acid ABC transporter permease protein YECS CysY aka B1918, component of Cystine/cysteine/diaminopimelate transporter, CysXYZ; these proteins are also designated FliY/YecS/YecC from Escherichia coli (see 4 papers)
36% identity, 95% coverage of query (135 bits)
ARTQ_BACSU / P54536 Arginine transport system permease protein ArtQ from Bacillus subtilis (strain 168) (see paper)
35% identity, 99% coverage of query (134 bits)
TCYB_BACSU / P42200 L-cystine transport system permease protein TcyB from Bacillus subtilis (strain 168) (see paper)
TC 3.A.1.3.14 / P42200 TcyB (YckJ), component of Uptake system for L-cystine from Bacillus subtilis (see 4 papers)
40% identity, 94% coverage of query (131 bits)
AO356_09910 ABC transporter for L-Lysine, permease component 2 from Pseudomonas fluorescens FW300-N2C3
35% identity, 98% coverage of query (124 bits)
YXEN_BACSU / P54953 Probable amino-acid permease protein YxeN from Bacillus subtilis (strain 168) (see paper)
32% identity, 98% coverage of query (122 bits)
TC 3.A.1.3.19 / Q88NY4 PP1069, component of Acidic amino acid uptake porter, AatJMQP from Pseudomonas putida (strain KT2440) (see paper)
34% identity, 100% coverage of query (120 bits)
TC 3.A.1.3.23 / Q9HU29 Amino acid (Lysine/arginine/ornithine/histidine/octopine) ABC transporter membrane protein, component of Amino acid transporter, PA5152-PA5155. Probably transports numerous amino acids including lysine, arginine, histidine, D-alanine and D-valine (Johnson et al. 2008). Regulated by ArgR from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
31% identity, 98% coverage of query (119 bits)
TC 3.A.1.3.22 / Q9I404 Amino acid ABC transporter membrane protein, component of Amino acid transporter, AatJMQP. Probably transports L-glutamic acid, D-glutamine acid, L-glutamine and N-acetyl L-glutamic acid (Johnson et al. 2008). Very similar to 3.A.1.3.19 of P. putida from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
33% identity, 98% coverage of query (116 bits)
AO353_16280 ABC transporter for L-aspartate, L-asparagine, L-glutamate, and L-glutamine, permease component 1 from Pseudomonas fluorescens FW300-N2E3
32% identity, 100% coverage of query (115 bits)
PfGW456L13_4772 ABC transporter for L-Asparagine and possibly other L-amino acids, permease component 2 from Pseudomonas fluorescens GW456-L13
32% identity, 100% coverage of query (115 bits)
AO353_21720 ABC transporter for D-glucosamine, permease component 2 from Pseudomonas fluorescens FW300-N2E3
34% identity, 96% coverage of query (113 bits)
Pf1N1B4_773 ABC transporter for L-asparagine and L-glutamate, permease subunit 2 from Pseudomonas fluorescens FW300-N1B4
31% identity, 100% coverage of query (113 bits)
TC 3.A.1.3.5 / P35114 OCM1 aka OccM, component of Octopine porter from Agrobacterium tumefaciens (see 2 papers)
32% identity, 97% coverage of query (112 bits)
TC 3.A.1.3.16 / A1VZQ3 PEP1B, component of Uptake system for glutamate and aspartate from Campylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176)
31% identity, 93% coverage of query (111 bits)
Pf6N2E2_2959 ABC transporter for L-Lysine, permease component 1 from Pseudomonas fluorescens FW300-N2E2
36% identity, 74% coverage of query (110 bits)
GLNM_BACSU / O34671 Probable glutamine ABC transporter permease protein GlnM from Bacillus subtilis (strain 168) (see paper)
30% identity, 98% coverage of query (110 bits)
AO356_05500 ABC transporter for L-Lysine, permease component 1 from Pseudomonas fluorescens FW300-N2C3
36% identity, 74% coverage of query (109 bits)
AO356_00470 ABC transporter for D-Glucosamine, permease component 1 from Pseudomonas fluorescens FW300-N2C3
Pf6N2E2_2051 ABC transporter for D-Glucosamine Hydrochloride, permease component 1 from Pseudomonas fluorescens FW300-N2E2
33% identity, 96% coverage of query (108 bits)
GltK / b0653 glutamate/aspartate ABC transporter membrane subunit GltK (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
GltK / P0AER5 glutamate/aspartate ABC transporter membrane subunit GltK (EC 7.4.2.1) from Escherichia coli (strain K12) (see 3 papers)
GLTK_ECOLI / P0AER5 Glutamate/aspartate import permease protein GltK from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.3.4 / P0AER5 Glutamate/aspartate transport system permease protein GltK aka B0653, component of Glutamate/aspartate porter from Escherichia coli (see 4 papers)
31% identity, 98% coverage of query (105 bits)
TC 3.A.1.3.18 / Q8YPM8 NatG, component of Acidic and neutral amino acid uptake transporter NatFGH/BgtA. BgtA is shared with BgtAB (see paper)
32% identity, 90% coverage of query (104 bits)
Pf1N1B4_3433 ABC transporter for L-Arginine and L-Citrulline, permease component 2 from Pseudomonas fluorescens FW300-N1B4
33% identity, 98% coverage of query (102 bits)
TC 3.A.1.3.11 / O50183 AotP aka AotM aka PA0890, component of Arginine/ornithine (but not lysine) porter from Pseudomonas aeruginosa (see 2 papers)
31% identity, 98% coverage of query (102 bits)
GLNP_BACSU / O34606 Probable glutamine ABC transporter permease protein GlnP from Bacillus subtilis (strain 168) (see paper)
34% identity, 91% coverage of query (102 bits)
AO356_09905 ABC transporter for L-Lysine, permease component 1 from Pseudomonas fluorescens FW300-N2C3
36% identity, 73% coverage of query (101 bits)
BPHYT_RS24010 L-histidine ABC transporter, permease component 2 from Burkholderia phytofirmans PsJN
30% identity, 99% coverage of query (100 bits)
Build an alignment for 14935 and 35 homologs with ≥ 30% identity
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TC 3.A.1.3.6 / P35113 NocM aka ATU6025 aka AGR_PTI_65, component of Nopaline porter from Agrobacterium tumefaciens (see 3 papers)
29% identity, 93% coverage of query (100 bits)
PS417_21735 ABC transporter for L-Arginine, permease component 2 from Pseudomonas simiae WCS417
34% identity, 98% coverage of query (99.8 bits)
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Lawrence Berkeley National Laboratory