Searching for up to 100 curated homologs for 15052 FitnessBrowser__Keio:15052 (396 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
Removed hits that are identical to the query, leaving 82
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
1aibA Structural basis for the catalytic activity of aspartate aminotransferase k258h lacking the pyridoxal-5'-phosphate binding lysine residue
100% identity, 100% coverage of query (822 bits)
1aiaA Structural basis for the catalytic activity of aspartate aminotransferase k258h lacking the pyridoxal-5'-phosphate binding lysine residue
100% identity, 100% coverage of query (822 bits)
1ascA The structural basis for the reduced activity of the d223a(d222a) active site mutant of e. Coli aspartate aminotransferase
100% identity, 100% coverage of query (821 bits)
8e9cB / P00509 Crystal structure of e. Coli aspartate aminotransferase mutant aifs in the ligand-free form at 100 k (see paper)
99% identity, 100% coverage of query (812 bits)
1ahxA Aspartate aminotransferase hexamutant
98% identity, 100% coverage of query (811 bits)
1ahgA Aspartate aminotransferase hexamutant
98% identity, 100% coverage of query (811 bits)
1ahfA Aspartate aminotransferase hexamutant
98% identity, 100% coverage of query (811 bits)
1yooA Aspartate aminotransferase mutant atb17 with isovaleric acid
96% identity, 100% coverage of query (792 bits)
2q7wA Structural studies reveals the inactivation of e. Coli l-aspartate aminotransferase (s)-4,5-amino-dihydro-2-thiophenecarboxylic acid (sadta) via two mechanisms at ph 6.0
96% identity, 100% coverage of query (778 bits)
aspC / Q3IED5 aspartate aminotransferase (EC 2.6.1.1) from Pseudoalteromonas translucida (strain TAC 125) (see paper)
maspC / CAA04961.1 aspartate aminotransferase from Moraxella sp (see paper)
52% identity, 100% coverage of query (426 bits)
HP15_858 phenylalanine aminotransferase (EC 2.6.1.57) from Marinobacter adhaerens HP15
49% identity, 100% coverage of query (395 bits)
W0PFQ7 aspartate transaminase (EC 2.6.1.1) from Advenella mimigardefordensis (see paper)
48% identity, 100% coverage of query (389 bits)
Pf6N2E2_2632 tyrosine aminotransferase (EC 2.6.1.57) from Pseudomonas fluorescens FW300-N2E2
49% identity, 99% coverage of query (385 bits)
AO356_03985 L-phenylalanine transaminase (EC 2.6.1.57) from Pseudomonas fluorescens FW300-N2C3
49% identity, 99% coverage of query (385 bits)
Psest_0779 tyrosine aminotransferase (EC 2.6.1.57) from Pseudomonas stutzeri RCH2
47% identity, 100% coverage of query (374 bits)
PfGW456L13_4396 tyrosine aminotransferase (EC 2.6.1.57) from Pseudomonas fluorescens GW456-L13
47% identity, 99% coverage of query (373 bits)
phhC / P43336 tyrosine aminotransferase subunit (EC 2.6.1.1) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
47% identity, 99% coverage of query (365 bits)
AO353_18575 tyrosine aminotransferase (EC 2.6.1.57) from Pseudomonas fluorescens FW300-N2E3
46% identity, 99% coverage of query (364 bits)
pat / Q5P8C9 aromatic-amino-acid aminotransferase (EC 2.6.1.1) from Aromatoleum aromaticum (strain EbN1) (see paper)
45% identity, 100% coverage of query (360 bits)
AAT2_ARATH / P46645 Aspartate aminotransferase, cytoplasmic isozyme 1; Transaminase A; EC 2.6.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see 6 papers)
44% identity, 100% coverage of query (356 bits)
TYRB_PARDE / P95468 Aromatic-amino-acid aminotransferase; ARAT; AROAT; EC 2.6.1.57 from Paracoccus denitrificans (see paper)
P95468 aromatic-amino-acid transaminase (EC 2.6.1.57) from Paracoccus denitrificans (see 4 papers)
1ay4A / P95468 Aromatic amino acid aminotransferase without substrate (see paper)
45% identity, 100% coverage of query (355 bits)
2ay9A Aromatic amino acid aminotransferase with 5-phenylvaleric acid
45% identity, 100% coverage of query (355 bits)
2ay8A Aromatic amino acid aminotransferase with 4-(2-thienyl)butyric acid
45% identity, 100% coverage of query (355 bits)
2ay7A Aromatic amino acid aminotransferase with 4-phenylbutyric acid
45% identity, 100% coverage of query (355 bits)
2ay6A Aromatic amino acid aminotransferase with 3-indolebutyric acid
45% identity, 100% coverage of query (355 bits)
2ay5A Aromatic amino acid aminotransferase with 3-indolepropionic acid
45% identity, 100% coverage of query (355 bits)
2ay3A Aromatic amino acid aminotransferase with 3-(3,4-dimethoxyphenyl) propionic acid
45% identity, 100% coverage of query (355 bits)
2ay1A Aromatic amino acid aminotransferase with 4-aminohydrocinnamic acid
45% identity, 100% coverage of query (355 bits)
AAT3_ARATH / P46644 Aspartate aminotransferase 3, chloroplastic; Protein YELLOW-LEAF-SPECIFIC GENE 4; Transaminase A; EC 2.6.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
44% identity, 100% coverage of query (352 bits)
PP_3590 aromatic-amino-acid transaminase (EC 2.6.1.57) from Pseudomonas putida KT2440
43% identity, 100% coverage of query (350 bits)
AAT5_ARATH / P46248 Aspartate aminotransferase, chloroplastic; Transaminase A; EC 2.6.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
45% identity, 99% coverage of query (349 bits)
RR42_RS33490 Aromatic-amino-acid aminotransferase (EC 2.6.1.57) from Cupriavidus basilensis FW507-4G11
43% identity, 100% coverage of query (346 bits)
tyrB / O85746 tyrosine aminotransferase monomer (EC 2.6.1.88) from Klebsiella pneumoniae (see paper)
TYRB_KLEPN / O85746 Tyrosine aminotransferase; TyrAT; Aromatic-amino-acid transaminase; Aspartate aminotransferase; EC 2.6.1.5; EC 2.6.1.57; EC 2.6.1.1 from Klebsiella pneumoniae (see paper)
43% identity, 100% coverage of query (345 bits)
3fslA / P04693 Crystal structure of tyrosine aminotransferase tripple mutant (p181q, r183g,a321k) from escherichia coli at 2.35 a resolution
43% identity, 100% coverage of query (345 bits)
4rkcA / C7E5X4 Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6 (see paper)
42% identity, 100% coverage of query (342 bits)
6zvgA Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6 cocrystalized with substrate analog - l-indole-3-lactic acid
42% identity, 100% coverage of query (342 bits)
6zurA Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6 cocrystalized with substrate analog - l-p-hydroxyphenyllactic acid
42% identity, 100% coverage of query (342 bits)
6zupA Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6 cocrystalized with substrate analog - l-(-)-3-phenyllactic acid
42% identity, 100% coverage of query (342 bits)
4rkdC Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6 cocrystalized with aspartic acid
42% identity, 100% coverage of query (342 bits)
4rkdA Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6 cocrystalized with aspartic acid
42% identity, 100% coverage of query (342 bits)
2ay4B Aromatic amino acid aminotransferase with 3-(p-tolyl)propionic acid
44% identity, 100% coverage of query (340 bits)
2ay2B Aromatic amino acid aminotransferase with cyclohexane propionic acid
44% identity, 100% coverage of query (340 bits)
1ay8B Aromatic amino acid aminotransferase complex with 3-phenylpropionate
44% identity, 100% coverage of query (340 bits)
TyrB / b4054 tyrosine aminotransferase (EC 2.6.1.57; EC 2.6.1.6; EC 2.6.1.42; EC 2.6.1.1; EC 2.6.1.5; EC 2.6.1.27) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
tyrB / P04693 tyrosine aminotransferase (EC 2.6.1.57; EC 2.6.1.6; EC 2.6.1.1) from Escherichia coli (strain K12) (see 3 papers)
TYRB_ECOLI / P04693 Aromatic-amino-acid aminotransferase; ARAT; AROAT; Beta-methylphenylalanine transaminase; EC 2.6.1.57; EC 2.6.1.107 from Escherichia coli (strain K12) (see paper)
P04693 aromatic-amino-acid transaminase (EC 2.6.1.57) from Escherichia coli (see paper)
tyrB / GB|AAC77024.1 aromatic-amino-acid transaminase TyrB; EC 2.6.1.57 from Escherichia coli K12 (see 5 papers)
43% identity, 100% coverage of query (338 bits)
3tatA Tyrosine aminotransferase from e. Coli
43% identity, 100% coverage of query (338 bits)
PGA1_c29420 aromatic-amino-acid transaminase [EC:2.6.1.57] from Phaeobacter inhibens BS107
44% identity, 99% coverage of query (332 bits)
tatA / AAA26362.1 tyrosine aminotransferase from Sinorhizobium meliloti (see paper)
44% identity, 96% coverage of query (330 bits)
AATM_DANRE / Q7SYK7 Aspartate aminotransferase, mitochondrial; mAspAT; Glutamate oxaloacetate transaminase 2a; Glutamic-oxaloacetic transaminase 2a, mitochondrial; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Transaminase A; EC 2.6.1.1; EC 2.6.1.7 from Danio rerio (Zebrafish) (Brachydanio rerio) (see paper)
40% identity, 99% coverage of query (325 bits)
AATM_MOUSE / P05202 Aspartate aminotransferase, mitochondrial; mAspAT; Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Plasma membrane-associated fatty acid-binding protein; FABPpm; Transaminase A; EC 2.6.1.1; EC 2.6.1.7 from Mus musculus (Mouse) (see 4 papers)
P05202 kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Mus musculus (see 3 papers)
42% identity, 99% coverage of query (323 bits)
Got2 / P00507 mitochondrial aspartate aminotransferase subunit (EC 2.6.1.1) from Rattus norvegicus (see 5 papers)
AATM_RAT / P00507 Aspartate aminotransferase, mitochondrial; mAspAT; Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Plasma membrane-associated fatty acid-binding protein; FABPpm; Transaminase A; EC 2.6.1.1; EC 2.6.1.7 from Rattus norvegicus (Rat) (see 2 papers)
P00507 aspartate transaminase (EC 2.6.1.1) from Rattus norvegicus (see 2 papers)
42% identity, 99% coverage of query (323 bits)
3pd6A Crystal structure of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-iv
42% identity, 99% coverage of query (323 bits)
P12344 Aspartate aminotransferase, mitochondrial; mAspAT; Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Plasma membrane-associated fatty acid-binding protein; FABPpm; Transaminase A; EC 2.6.1.1 from Bos taurus (Bovine)
42% identity, 99% coverage of query (323 bits)
AATM_CHICK / P00508 Aspartate aminotransferase, mitochondrial; mAspAT; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Transaminase A; EC 2.6.1.1; EC 2.6.1.7 from Gallus gallus (Chicken) (see 4 papers)
41% identity, 99% coverage of query (321 bits)
7aatA / P00508 X-ray structure refinement and comparison of three forms of mitochondrial aspartate aminotransferase (see paper)
41% identity, 99% coverage of query (320 bits)
9aatA X-ray structure refinement and comparison of three forms of mitochondrial aspartate aminotransferase
41% identity, 99% coverage of query (320 bits)
1oxoA Aspartate aminotransferase, h-asp complex, open conformation
41% identity, 99% coverage of query (320 bits)
1maqA Crystal structures of true enzymatic reaction intermediates: aspartate and glutamate ketimines in aspartate aminotransferase
41% identity, 99% coverage of query (320 bits)
1mapA Crystal structures of true enzymatic reaction intermediates: aspartate and glutamate ketimines in aspartate aminotransferase
41% identity, 99% coverage of query (320 bits)
1ivrA Structure of aspartate aminotransferase
41% identity, 99% coverage of query (320 bits)
1amaA Domain closure in mitochondrial aspartate aminotransferase
41% identity, 99% coverage of query (320 bits)
1akcA Structural basis for the catalytic activity of aspartate aminotransferase k258h lacking its pyridoxal-5'-phosphate-binding lysine residue
40% identity, 99% coverage of query (318 bits)
1akbA Structural basis for the catalytic activity of aspartate aminotransferase k258h lacking its pyridoxal-5'-phosphate-binding lysine residue
40% identity, 99% coverage of query (318 bits)
1akaB Structural basis for the catalytic activity of aspartate aminotransferase k258h lacking its pyridoxal-5'-phosphate-binding lysine residue
40% identity, 99% coverage of query (318 bits)
GOT2 / P00505 Aspartate aminotransferase, mitochondrial (EC 2.6.1.23; EC 2.6.1.1; EC 2.6.1.7) from Homo sapiens (see 4 papers)
AATM_HUMAN / P00505 Aspartate aminotransferase, mitochondrial; mAspAT; Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Plasma membrane-associated fatty acid-binding protein; FABPpm; Transaminase A; EC 2.6.1.1; EC 2.6.1.7 from Homo sapiens (Human) (see 3 papers)
P00505 aspartate transaminase (EC 2.6.1.1) from Homo sapiens (see 2 papers)
TC 9.A.70.1.1 / P00505 Mitochondrial aspartate amino transferase of 430 aas and 1 TMS, AAT or GOT2 from Homo sapiens
41% identity, 99% coverage of query (317 bits)
8skrA / P00505 8skrA (see paper)
41% identity, 99% coverage of query (317 bits)
AATM_SCHPO / O94320 Aspartate aminotransferase, mitochondrial; Transaminase A; EC 2.6.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
40% identity, 100% coverage of query (309 bits)
AAT1 potential aspartate aminotransferase from Candida albicans (see paper)
40% identity, 100% coverage of query (307 bits)
GOT1 / P17174 cytoplasmic aspartate aminotransferase (EC 2.6.1.1; EC 2.6.1.3) from Homo sapiens (see 4 papers)
AATC_HUMAN / P17174 Aspartate aminotransferase, cytoplasmic; cAspAT; Cysteine aminotransferase, cytoplasmic; Cysteine transaminase, cytoplasmic; cCAT; Glutamate oxaloacetate transaminase 1; Transaminase A; EC 2.6.1.1; EC 2.6.1.3 from Homo sapiens (Human) (see 4 papers)
P17174 aspartate transaminase (EC 2.6.1.1); glutamine-phenylpyruvate transaminase (EC 2.6.1.64) from Homo sapiens (see 4 papers)
42% identity, 97% coverage of query (303 bits)
AAT1_ARATH / P46643 Aspartate aminotransferase, mitochondrial; Transaminase A; EC 2.6.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
39% identity, 99% coverage of query (303 bits)
6ligA Crystal structure of human glutamate oxaloacetate transaminase 1 (got1) in complex with ah
42% identity, 97% coverage of query (303 bits)
3ii0C / P17174 Crystal structure of human glutamate oxaloacetate transaminase 1 (got1)
42% identity, 96% coverage of query (302 bits)
AATC_MOUSE / P05201 Aspartate aminotransferase, cytoplasmic; cAspAT; Cysteine aminotransferase, cytoplasmic; Cysteine transaminase, cytoplasmic; cCAT; Glutamate oxaloacetate transaminase 1; Transaminase A; EC 2.6.1.1; EC 2.6.1.3 from Mus musculus (Mouse) (see paper)
41% identity, 99% coverage of query (302 bits)
3ii0A Crystal structure of human glutamate oxaloacetate transaminase 1 (got1)
42% identity, 96% coverage of query (301 bits)
Got1 / P13221 cysteine aminotransferase subunit (EC 2.6.1.1; EC 2.6.1.3) from Rattus norvegicus (see 4 papers)
AATC_RAT / P13221 Aspartate aminotransferase, cytoplasmic; cAspAT; Cysteine aminotransferase, cytoplasmic; Cysteine transaminase, cytoplasmic; cCAT; Glutamate oxaloacetate transaminase 1; Transaminase A; EC 2.6.1.1; EC 2.6.1.3 from Rattus norvegicus (Rat) (see 7 papers)
41% identity, 99% coverage of query (300 bits)
AAT3 / Q43305 aspartate transaminase (EC 2.6.1.1) from Panicum miliaceum (see paper)
39% identity, 100% coverage of query (299 bits)
Q964F0 aspartate transaminase (EC 2.6.1.1) from Trypanosoma brucei (see paper)
41% identity, 96% coverage of query (298 bits)
6dnbA Crystal structure of t110a:s256a mutant human glutamate oxaloacetate transaminase 1 (got1)
42% identity, 97% coverage of query (298 bits)
Q4D080 aspartate transaminase (EC 2.6.1.1) from Trypanosoma cruzi (see paper)
cASAT aminotransferase; EC 2.6.1.- from Trypanosoma cruzi strain CL Brener (see paper)
42% identity, 100% coverage of query (296 bits)
Q385Q9 aspartate transaminase (EC 2.6.1.1) from Trypanosoma brucei brucei (see paper)
mASAT aspartate aminotransferase; EC 2.6.1.1 from Trypanosoma brucei TREU927 (see paper)
41% identity, 96% coverage of query (296 bits)
6jpkA / O42652 Crystal structure of s. Pombe aspartate aminotransferase (see paper)
39% identity, 99% coverage of query (295 bits)
2cstA / P00504 Crystal structure of the closed form of chicken cytosolic aspartate aminotransferase at 1.9 angstroms resolution (see paper)
39% identity, 99% coverage of query (295 bits)
AATC_CHICK / P00504 Aspartate aminotransferase, cytoplasmic; cAspAT; Cysteine aminotransferase, cytoplasmic; Cysteine transaminase, cytoplasmic; cCAT; Glutamate oxaloacetate transaminase 1; Transaminase A; EC 2.6.1.1; EC 2.6.1.3 from Gallus gallus (Chicken) (see 2 papers)
39% identity, 99% coverage of query (295 bits)
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Lawrence Berkeley National Laboratory