Searching for up to 100 curated homologs for 15363 FitnessBrowser__Keio:15363 (543 a.a.)
Found high-coverage hits (≥70%) to 88 curated proteins.
Removed hits that are identical to the query, leaving 86
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TC 3.A.1.5.1 / P06202 OppA aka STM1746, component of Oligopeptide porter (also takes up amino glycoside antibiotics such as kanamycin, streptomycin and neomycin as well as cell wall-derived peptides such as murein tripeptide). It transports substrate peptides of 2-5 amino acids with highest affinity for tripeptides. Also transports δ-aminolevulinic acid (ALA). [May be regulated by PTS Enzyme INtr-aspartokinase.] ATP-binding to OppDF may result in donation of peptide to OppBC and simultaneous release of OppA from Salmonella typhimurium (see 7 papers)
85% identity, 100% coverage of query (965 bits)
1b05A / P06202 Structure of oligo-peptide binding protein complexed with lys-cys-lys (see paper)
86% identity, 95% coverage of query (947 bits)
2rkmA Structure of oppa complexed with lys-lys
86% identity, 95% coverage of query (947 bits)
1olcA Oligo-peptide binding protein (oppa) complexed with lys-lys- lys-ala
86% identity, 95% coverage of query (947 bits)
2z23A / A0A0H2W5P5 Crystal structure of y.Pestis oligo peptide binding protein oppa with tri-lysine ligand (see paper)
78% identity, 95% coverage of query (852 bits)
Q5V9S2 ABC-type oligopeptide transporter (EC 7.4.2.6) from Vibrio fluvialis (see paper)
TC 3.A.1.5.22 / Q5V9S2 OppA, component of The peptide transporter OppA,B,C,D,F (influences biofilm formation; Lee et al., 2004). Similar to 3.A.1.5.1, OppA is similar to the Vibrio furnissii OppA that provides several functions: hemolysis, antibiotic resistance, and virulence from Vibrio fluvialis (see paper)
52% identity, 99% coverage of query (583 bits)
Q0PRU9 ABC-type oligopeptide transporter (EC 7.4.2.6) from Vibrio furnissii (see paper)
52% identity, 99% coverage of query (568 bits)
6dtgA / Q4QLH0 Crystal structure of haemophilus influenzae oppa complex with ylgangrgggs (see paper)
54% identity, 95% coverage of query (566 bits)
YnaH / b1329 murein tripeptide ABC transporter periplasmic binding protein (EC 7.4.2.6) from Escherichia coli K-12 substr. MG1655 (see 10 papers)
mppA / P77348 murein tripeptide ABC transporter periplasmic binding protein (EC 7.4.2.6) from Escherichia coli (strain K12) (see 9 papers)
TC 3.A.1.5.1 / TC 3.A.1.5.41 / P77348 MppA aka B1329, component of Oligopeptide transporter, OppABCDF/MppA/YgiS from Escherichia coli (see 4 papers)
48% identity, 97% coverage of query (508 bits)
3o9pA / P77348 The structure of the escherichia coli murein tripeptide binding protein mppa (see paper)
49% identity, 94% coverage of query (493 bits)
YgiS / b3020 putative deoxycholate binding periplasmic protein from Escherichia coli K-12 substr. MG1655 (see 5 papers)
YGIS_ECOLI / Q46863 Probable deoxycholate-binding periplasmic protein YgiS from Escherichia coli (strain K12) (see paper)
TC 3.A.1.5.41 / Q46863 Probable deoxycholate-binding periplasmic protein YgiS, component of Oligopeptide transporter, OppABCDF/MppA/YgiS from Escherichia coli (strain K12)
44% identity, 97% coverage of query (451 bits)
3zs6A / Q63ID0 The structural characterization of burkholderia pseudomallei oppa. (see paper)
43% identity, 94% coverage of query (424 bits)
H7C7K8 ABC-type oligopeptide transporter (EC 7.4.2.6) from Borreliella burgdorferi (see paper)
TC 3.A.1.5.18 / O31315 OppA4, component of The oligopeptide transporter OppA1-5, B1, C1, DF (functions with five binding proteins of differing induction properties and peptide specificities; OppA1-3 are chromosomally encoded; OppA4 and 5 are plasmid encoded.) from Borrelia burgdorferi (Lyme disease spirochete) (see 2 papers)
35% identity, 83% coverage of query (282 bits)
4gl8A / H7C7K8 X-ray crystal structure of a periplasmic oligopeptide-binding protein/oligopeptide abc transporter(oppaiv) from borrelia burgdorferi
35% identity, 83% coverage of query (281 bits)
TC 3.A.1.5.18 / O54584 OppA2, component of The oligopeptide transporter OppA1-5, B1, C1, DF (functions with five binding proteins of differing induction properties and peptide specificities; OppA1-3 are chromosomally encoded; OppA4 and 5 are plasmid encoded.) from Borrelia burgdorferi (Lyme disease spirochete) (see 3 papers)
33% identity, 88% coverage of query (275 bits)
OPPA_BACSU / P24141 Oligopeptide-binding protein OppA; Stage 0 sporulation protein KA from Bacillus subtilis (strain 168) (see 5 papers)
34% identity, 88% coverage of query (274 bits)
8arnA / P24141 Crystal structure of the peptide binding protein, oppa, from bacillus subtilis in complex with an endogenous tetrapeptide (see paper)
34% identity, 88% coverage of query (273 bits)
TC 3.A.1.5.18 / O51308 OppA3, component of The oligopeptide transporter OppA1-5, B1, C1, DF (functions with five binding proteins of differing induction properties and peptide specificities; OppA1-3 are chromosomally encoded; OppA4 and 5 are plasmid encoded.) from Borrelia burgdorferi (Lyme disease spirochete) (see paper)
33% identity, 92% coverage of query (263 bits)
TC 3.A.1.5.18 / O51307 OppA1, component of The oligopeptide transporter OppA1-5, B1, C1, DF (functions with five binding proteins of differing induction properties and peptide specificities; OppA1-3 are chromosomally encoded; OppA4 and 5 are plasmid encoded.) from Borrelia burgdorferi (Lyme disease spirochete) (see paper)
33% identity, 88% coverage of query (249 bits)
DPPE_BACSU / P26906 Dipeptide-binding protein DppE from Bacillus subtilis (strain 168) (see paper)
TC 3.A.1.5.2 / P26906 DppE aka DCIAE, component of Dipeptide porter. Also transports δ-aminolevulinic acid (ALA) and heme from Bacillus subtilis (see 3 papers)
32% identity, 95% coverage of query (242 bits)
8ay0B / P26906 Crystal structure of the peptide binding protein dppe from bacillus subtilis in complex with murein tripeptide (see paper)
32% identity, 90% coverage of query (240 bits)
TC 3.A.1.5.18 / O50927 OppA5, component of The oligopeptide transporter OppA1-5, B1, C1, DF (functions with five binding proteins of differing induction properties and peptide specificities; OppA1-3 are chromosomally encoded; OppA4 and 5 are plasmid encoded.) from Borrelia burgdorferi (Lyme disease spirochete) (see paper)
30% identity, 96% coverage of query (220 bits)
6npoA / Q81YA8 Crystal structure of oligopeptide abc transporter from bacillus anthracis str. Ames (substrate-binding domain)
31% identity, 90% coverage of query (212 bits)
5kztB / A0A0H3GJB6 Listeria monocytogenes oppa bound to peptide
31% identity, 93% coverage of query (198 bits)
Build an alignment for 15363 and 24 homologs with ≥ 30% identity
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TC 3.A.1.5.19 / Q2FZR3 OppA, component of The major oligopeptide uptake porter, Opp-3 (of four paralogues, this is the only one that mediates nitrogen nutrition from Staphylococcus aureus (strain NCTC 8325)
28% identity, 94% coverage of query (182 bits)
4fajA / Q51643 Structure and mode of peptide binding of pheromone receptor prgz (see paper)
28% identity, 88% coverage of query (177 bits)
TC 3.A.1.5.25 / Q64K09 OptS, component of The ABC peptide/signalling peptide transporter. OptA binds peptides of 3-6 aas; OptS binds dipeptides. OptB,C,D are most similar to 3.A.1.5.19 from Lactococcus lactis (see paper)
29% identity, 91% coverage of query (172 bits)
DPPA_LACLM / A2RI74 Dipeptide-binding protein from Lactococcus lactis subsp. cremoris (strain MG1363) (see 2 papers)
29% identity, 91% coverage of query (172 bits)
TC 3.A.1.5.25 / Q9CIL2 Oligopeptide ABC transporter substrate binding protein, component of The ABC peptide/signalling peptide transporter. OptA binds peptides of 3-6 aas; OptS binds dipeptides. OptB,C,D are most similar to 3.A.1.5.19 from Lactococcus lactis subsp. lactis (see paper)
30% identity, 87% coverage of query (171 bits)
has / CAA78270.1 threonine kinase from Streptococcus dysgalactiae subsp. equisimilis (see 3 papers)
31% identity, 75% coverage of query (142 bits)
GsiB / b0830 glutathione ABC transporter periplasmic binding protein (EC 7.4.2.10) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
gsiB / P75797 glutathione ABC transporter periplasmic binding protein (EC 7.4.2.10) from Escherichia coli (strain K12) (see 2 papers)
GSIB_ECOLI / P75797 Glutathione-binding protein GsiB from Escherichia coli (strain K12) (see 2 papers)
P75797 ABC-type glutathione transporter (EC 7.4.2.10) from Escherichia coli (see paper)
TC 3.A.1.5.11 / P75797 Putative binding protein yliB, component of Glutathione porter, YliABCD or GsiABCD from Escherichia coli (see 6 papers)
26% identity, 93% coverage of query (140 bits)
DdpA / b1487 putative D,D-dipeptide ABC transporter periplasmic binding protein from Escherichia coli K-12 substr. MG1655 (see 4 papers)
DDPA_ECOLI / P76128 Probable D,D-dipeptide-binding periplasmic protein DdpA from Escherichia coli (strain K12) (see paper)
ddpA / RF|NP_416004.1 dipeptide ABC transporter, permease protein DdpA from Escherichia coli K12 (see paper)
26% identity, 93% coverage of query (139 bits)
6ofqA / A0A1U9ISL1 Abc transporter-associated periplasmic binding protein dppa from helicobacter pylori in complex with peptide stsa (see paper)
27% identity, 87% coverage of query (135 bits)
8upiA Structure of a periplasmic peptide binding protein from mesorhizobium sp. Ap09 bound to aminoserine
26% identity, 91% coverage of query (134 bits)
7kz9A Crystal structure of pseudomonas sp. Pdc86 substrate-binding protein aapf in complex with a signaling molecule heheaa (see paper)
26% identity, 85% coverage of query (129 bits)
1uqwA / P75797 Crystal structure of ylib protein from escherichia coi
26% identity, 85% coverage of query (129 bits)
3m8uA / B8F653 Crystal structure of glutathione-binding protein a (gbpa) from haemophilus parasuis sh0165 in complex with glutathione disulfide (gssg) (see paper)
25% identity, 83% coverage of query (123 bits)
Dpp / b3544 dipeptide ABC transporter periplasmic binding protein (EC 7.4.2.9) from Escherichia coli K-12 substr. MG1655 (see 18 papers)
dppA / P23847 dipeptide ABC transporter periplasmic binding protein (EC 7.4.2.9) from Escherichia coli (strain K12) (see 19 papers)
DPPA_ECOLI / P23847 Dipeptide-binding protein; DBP; Periplasmic dipeptide transport protein from Escherichia coli (strain K12) (see 8 papers)
dppA / GB|AAC76569.1 dipeptide ABC transporter, periplasmic dipeptide-binding protein DppA from Escherichia coli K12 (see 11 papers)
25% identity, 84% coverage of query (118 bits)
1dppA / P23847 Dipeptide binding protein complex with glycyl-l-leucine (see paper)
25% identity, 84% coverage of query (117 bits)
6hlxA / O50260 Structure of the pbp agaa in complex with agropinic acid from a.Tumefacien r10 (see paper)
24% identity, 90% coverage of query (114 bits)
2nooA Crystal structure of mutant nika
25% identity, 87% coverage of query (110 bits)
7a0cA X-ray structure of nika from escherichia coli in complex with fe-6- me2-bpmcn
25% identity, 87% coverage of query (108 bits)
5on1A Crystal structure of nika in complex with hydroxylated fe-l1 (n-(2- hydroxybenzyl)-n'-(2-thiomethylbenzyl)-n,n'-ethylenediamine diacetic acid)
25% identity, 87% coverage of query (108 bits)
5on0A Crystal structure of nika in complex with fe-l2 (n-(2-hydroxy- 3methoxybenzyl)-n-n'-ethylenediaminediacetic acid)
25% identity, 87% coverage of query (108 bits)
3mw0A X-ray structure of the doubly hydroxylated iron complex-nika species, nika1/o2
25% identity, 87% coverage of query (108 bits)
3mvzA X-ray structure of the (hydro)peroxo intermediate nika/1-int", after monohydroxylation of the iron complex
25% identity, 87% coverage of query (108 bits)
3mvwA X-ray structure of a "nika+iron complex" hybrid, nika/1
25% identity, 87% coverage of query (108 bits)
4dcxA X-ray structure of nika in complex with fe(1r,2r)-n,n'-bis(2- pyridylmethyl)-n,n'-dicarboxymethyl-1,2-cyclohexanediamine
25% identity, 87% coverage of query (108 bits)
5l8dB X-ray structure of nika from escherichia coli in complex with ru(bis(pyrzol-1-yl)acetate scorpionate)(co)2cl
25% identity, 87% coverage of query (108 bits)
4i9dA X-ray structure of nika in complex with fe-n,n'-bis(2-pyridylmethyl)- n-carboxymethyl-n'-methyl
25% identity, 87% coverage of query (108 bits)
4dcyA X-ray structure of nika in complex with fe(1s,2s)-n,n-kappa-bis(2- pyridylmethyl)-n-carboxymethyl-n-kappa-methyl-1,2-cyclohexanediamine
25% identity, 87% coverage of query (108 bits)
4i8cA X-ray structure of nika in complex with ni-(l-his)2
25% identity, 87% coverage of query (108 bits)
5f1qA / A0A0H2YM47 Crystal structure of periplasmic dipeptide transport protein from yersinia pestis
24% identity, 83% coverage of query (108 bits)
1zlqA Crystallographic and spectroscopic evidence for high affinity binding of fe edta (h2o)- to the periplasmic nickel transporter nika
25% identity, 87% coverage of query (108 bits)
3e3kB / P33590 Structural characterization of a putative endogenous metal chelator in the periplasmic nickel transporter nika (butane-1,2,4-tricarboxylate without nickel form) (see paper)
25% identity, 87% coverage of query (108 bits)
4qfpA Crystal structure of dipeptide binding protein from pseudoalteromonas sp. Sm9913 in complex with val-thr
24% identity, 82% coverage of query (100 bits)
4qfoA Crystal structure of dipeptide binding protein from pseudoalteromonas sp. Sm9913 in complex with met-leu
24% identity, 82% coverage of query (100 bits)
4qfnA Crystal structure of dipeptide binding protein from pseudoalteromonas sp. Sm9913 in complex with gly-glu
24% identity, 82% coverage of query (100 bits)
4qflA / A7Y7W1 Crystal structure of dipeptide binding protein from pseudoalteromonas sp. Sm9913 in complex with ala-phe (see paper)
24% identity, 82% coverage of query (100 bits)
6e3dA / I6X811 Atomic structure of mycobacterium tuberculosis dppa (see paper)
25% identity, 87% coverage of query (96.7 bits)
4oesA / Q9AL82 Crystal structure of nika from brucella suis in complex with fe(iii)- edta (see paper)
24% identity, 88% coverage of query (90.9 bits)
2wopA / Q8KRB4 Clavulanic acid biosynthesis oligopeptide binding protein 2 complexed with arginine (see paper)
23% identity, 81% coverage of query (80.1 bits)
2wokA Clavulanic acid biosynthesis oligopeptide binding protein 2 complexed with bradykinin
23% identity, 81% coverage of query (79.7 bits)
4jsdA The x-ray crystal structure of a thermophilic cellobiose binding protein bound with laminaribiose
24% identity, 83% coverage of query (74.7 bits)
3i5oA / Q9WXN8 The x-ray crystal structure of a thermophilic cellobiose binding protein bound with cellopentaose (see paper)
24% identity, 83% coverage of query (74.7 bits)
7ebiA Chitin-specific solute binding protein from vibrio harveyi co- crystalized with chitotetraose. (see paper)
23% identity, 83% coverage of query (71.2 bits)
8cayA Pbp acca from a. Tumefaciens bo542 in complex with agrocinopine d-like
23% identity, 85% coverage of query (65.1 bits)
8cawA / A0A2P0QK24 Pbp acca from a. Tumefaciens bo542 in complex with agrocin84 (see paper)
23% identity, 85% coverage of query (65.1 bits)
4pfyA / Q9X0V0 Crystal structure of mannohexaose bound oligopeptide abc transporter, periplasmic oligopeptide-binding protein (tm1223) from thermotoga maritima at 1.5 a resolution (see paper)
24% identity, 81% coverage of query (64.7 bits)
1xocA / P42061 The structure of the oligopeptide-binding protein, appa, from bacillus subtilis in complex with a nonapeptide. (see paper)
22% identity, 83% coverage of query (64.7 bits)
8cdoA Pbp acca-f144yg440q from a. Tumefaciens bo542 in complex with agrocinopinE C-like
22% identity, 85% coverage of query (63.9 bits)
8cb9A Pbp acca from a. Tumefaciens bo542 in complex with d-glucose-2- phosphate
23% identity, 85% coverage of query (63.5 bits)
8i5jA Crystal structure of chitin oligosaccharide binding protein from vibrio cholera.
21% identity, 83% coverage of query (62.8 bits)
4gfrA / Q9KUA3 Crystal structure of the liganded chitin oligasaccharide binding protein
21% identity, 83% coverage of query (62.8 bits)
3rybA / A2RJ53 Lactococcal oppa complexed with slsqslsqs (see paper)
23% identity, 81% coverage of query (62.0 bits)
4oflA Crystal structure of ynta from yersinia pestis in complex with ni(l- his)2
21% identity, 76% coverage of query (59.7 bits)
4ofoA / A0A5P8YI66 Crystal structure of ynta from yersinia pestis, unliganded form (see paper)
21% identity, 76% coverage of query (59.7 bits)
CNTA_STAA8 / Q2FVE7 Metal-staphylopine-binding protein CntA from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see 3 papers)
TC 3.A.1.5.43 / Q2FVE7 Peptide ABC transporter, peptide-binding protein, putative, component of The metal-staphylopine (nicotianamine-like metalophore) complex uptake system, CntABCDF from Staphylococcus aureus (strain NCTC 8325)
22% identity, 94% coverage of query (58.9 bits)
7ofwA Nontypeable haemophillus influenzae sapa in complex with heme
21% identity, 84% coverage of query (56.6 bits)
4pfuB / G4FEC0 Crystal structure of mannobiose bound oligopeptide abc transporter, periplasmic oligopeptide-binding protein (tm1226) from thermotoga maritima at 2.05 a resolution (see paper)
22% identity, 81% coverage of query (55.5 bits)
5hm4B Crystal structure of oligopeptide abc transporter, periplasmic oligopeptide-binding protein (tm1226) from thermotoga maritima at 2.0 a resolution
22% identity, 81% coverage of query (55.1 bits)
4pfwA Crystal structure of mannohexaose bound oligopeptide abc transporter, periplasmic oligopeptide-binding protein (tm1226) from thermotoga maritima at 2.2 a resolution
22% identity, 81% coverage of query (55.1 bits)
7z8eA / A0A222JNH8 Crystal structure of the substrate-binding protein yeja from s. Meliloti in complex with peptide fragment (see paper)
20% identity, 94% coverage of query (53.5 bits)
5yh8A / Q2FVE7 The crystal structure of staphylococcus aureus cnta in complex with staphylopine and nickel (see paper)
21% identity, 87% coverage of query (52.8 bits)
4oevA / Q0P844 Crystal structure of nikz from campylobacter jejuni in complex with ni(ii) ion (see paper)
21% identity, 84% coverage of query (48.5 bits)
4oeuA Crystal structure of nikz from campylobacter jejuni in complex with ni(l-his)
21% identity, 84% coverage of query (48.1 bits)
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Lawrence Berkeley National Laboratory