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Searching for up to 100 curated homologs for 15421 FitnessBrowser__Keio:15421 (426 a.a.)

Found high-coverage hits (≥70%) to 20 curated proteins.

Removed hits that are identical to the query, leaving 19

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AO356_21495 gamma-glutamylputrescine oxidase (EC 1.4.3.-) from Pseudomonas fluorescens FW300-N2C3
    66% identity, 100% coverage of query (583 bits)

Pf6N2E2_80 gamma-glutamylputrescine oxidase (EC 1.4.3.-) from Pseudomonas fluorescens FW300-N2E2
    67% identity, 92% coverage of query (555 bits)

Q1XEP4 taurine dehydrogenase (EC 1.4.99.2) from Paracoccus versutus (see paper)
    32% identity, 97% coverage of query (167 bits)

Q6RH53 taurine dehydrogenase (EC 1.4.99.2) from Paracoccus pantotrophus (see paper)
    32% identity, 97% coverage of query (165 bits)

Q6RH61 taurine dehydrogenase (EC 1.4.99.2) from Paracoccus denitrificans (see paper)
    33% identity, 99% coverage of query (160 bits)

Build an alignment

Build an alignment for 15421 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

nmpC / A0A222FYP8 4-methylaminobutanoate oxidase (EC 1.5.3.21) from Alicycliphilus sp. (see paper)
    29% identity, 93% coverage of query (154 bits)

Q6RH44 taurine dehydrogenase (EC 1.4.99.2) from Paracoccus pantotrophus (see paper)
    32% identity, 97% coverage of query (152 bits)

amaA / Q88CC4 pipecolate oxidase (EC 1.5.3.7) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 3 papers)
    32% identity, 92% coverage of query (145 bits)

O59445 proline dehydrogenase (EC 1.5.5.2) from Pyrococcus horikoshii (see paper)
    21% identity, 83% coverage of query (75.5 bits)

Q8U022 proline dehydrogenase (EC 1.5.5.2) from Pyrococcus furiosus (see paper)
    21% identity, 83% coverage of query (71.2 bits)

7cyxA / Q81HQ7 Crystal strcuture of glycine oxidase from bacillus cereus atcc 14579 (see paper)
    22% identity, 84% coverage of query (60.5 bits)

L7T8Y9 glycine oxidase (EC 1.4.3.19) from Bacillus cereus (see 2 papers)
    22% identity, 84% coverage of query (59.3 bits)

lhpB / Q9I477 D-hydroxyproline dehydrogenase β subunit from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    25% identity, 87% coverage of query (58.2 bits)

Q5JFG2 proline dehydrogenase (EC 1.5.5.2) from Thermococcus kodakarensis (see paper)
    23% identity, 81% coverage of query (57.8 bits)

GLYOX_BACLI / S5FMM4 Glycine oxidase; GO; BliGO; EC 1.4.3.19 from Bacillus licheniformis (see paper)
S5FMM4 glycine oxidase (EC 1.4.3.19) from Bacillus licheniformis (see paper)
    23% identity, 83% coverage of query (51.2 bits)

5i39A / Q9LCB2 High resolution structure of l-amino acid deaminase from proteus vulgaris with the deletion of the specific insertion sequence (see paper)
    22% identity, 85% coverage of query (50.1 bits)

Q76M73 proline dehydrogenase (EC 1.5.5.2) from Thermococcus profundus (see 2 papers)
    22% identity, 81% coverage of query (48.9 bits)

O59089 proline dehydrogenase (EC 1.5.5.2) from Pyrococcus horikoshii (see paper)
    22% identity, 80% coverage of query (48.9 bits)

1y56B / O59089 Crystal structure of l-proline dehydrogenase from p.Horikoshii (see paper)
    22% identity, 80% coverage of query (48.9 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory