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Searching for up to 100 curated homologs for 15434 FitnessBrowser__Keio:15434 (262 a.a.)

Found high-coverage hits (≥70%) to 30 curated proteins.

Removed hits that are identical to the query, leaving 28

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

3kwsA / A6LIL3 Crystal structure of putative sugar isomerase (yp_001305149.1) from parabacteroides distasonis atcc 8503 at 1.68 a resolution
    30% identity, 87% coverage of query (96.7 bits)

5h1wA / Q9WYP7 Crystal structure of hyperthermophilic thermotoga maritima l-ketose-3- epimerase with mn2+ and l(+)-erythrulose (see paper)
    30% identity, 91% coverage of query (90.9 bits)

iolO / Q9WYP7 5-dehydro-L-gluconate epimerase from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 2 papers)
IOLO_THEMA / Q9WYP7 5-keto-L-gluconate epimerase; Bifunctional nonphosphorylated sugar isomerase; D-erythrose/D-threose isomerase; L-ribulose 3-epimerase; R3E; Nonphosphorylated sugar 3-epimerase; Nonphosphorylated sugar aldose-ketose isomerase; EC 5.1.3.-; EC 5.3.1.- from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 2 papers)
    30% identity, 91% coverage of query (90.9 bits)

Build an alignment

Build an alignment for 15434 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

B0NGC5 D-psicose 3-epimerase (EC 5.1.3.30) from [Clostridium] scindens (see paper)
    26% identity, 86% coverage of query (90.9 bits)

5b80A Crystal structure of hyperthermophilic thermotoga maritima l-ketose-3- epimerase with cu2+
    30% identity, 91% coverage of query (90.9 bits)

5b7yA Crystal structure of hyperthermophilic thermotoga maritima l-ketose-3- epimerase with co2+
    30% identity, 91% coverage of query (90.9 bits)

KET3E_ARTGO / A0A1L7NQ96 Ketose 3-epimerase; D-allulose 3-epimerase; D-AE; L-ribulose 3-epimerase; EC 5.1.3.- from Arthrobacter globiformis (see 2 papers)
    29% identity, 92% coverage of query (81.6 bits)

5zfsB / A0A1L7NQ96 Crystal structure of arthrobacter globiformis m30 sugar epimerase which can produce d-allulose from d-fructose (see paper)
    29% identity, 92% coverage of query (81.3 bits)

7x7wA The x-ray crystallographic structure of d-psicose 3-epimerase from clostridia bacterium
    26% identity, 84% coverage of query (77.4 bits)

7cj9D Crystal structure of n-terminal his-tagged d-allulose 3-epimerase from methylomonas sp. With additional c-terminal residues
    27% identity, 85% coverage of query (75.5 bits)

AB000361 / O50580 D-tagatose 3-epimerase (EC 5.1.3.31) from Pseudomonas cichorii (see 2 papers)
DT3E_PSECI / O50580 D-tagatose 3-epimerase; DTE; D-ribulose 3-epimerase; Ketose 3-epimerase; EC 5.1.3.31 from Pseudomonas cichorii (see 2 papers)
O50580 D-tagatose 3-epimerase (EC 5.1.3.31) from Pseudomonas cichorii (see 3 papers)
    28% identity, 86% coverage of query (74.3 bits)

2qumA Crystal structure of d-tagatose 3-epimerase from pseudomonas cichorii with d-tagatose
    28% identity, 86% coverage of query (74.3 bits)

4ytuA Crystal structure of d-tagatose 3-epimerase c66s from pseudomonas cichorii in complex with l-erythrulose
    28% identity, 86% coverage of query (74.3 bits)

4yttA Crystal structure of d-tagatose 3-epimerase c66s from pseudomonas cichorii in complex with 6-deoxy l-psicose
    28% identity, 86% coverage of query (74.3 bits)

4ytsA Crystal structure of d-tagatose 3-epimerase c66s from pseudomonas cichorii in complex with 1-deoxy 3-keto d-galactitol
    28% identity, 86% coverage of query (74.3 bits)

4ytrA Crystal structure of d-tagatose 3-epimerase c66s from pseudomonas cichorii in complex with 1-deoxy l-tagatose
    28% identity, 86% coverage of query (74.3 bits)

4ytqA Crystal structure of d-tagatose 3-epimerase c66s from pseudomonas cichorii in complex with 1-deoxy d-tagatose
    28% identity, 86% coverage of query (74.3 bits)

4xsmA Crystal structure of d-tagatose 3-epimerase c66s from pseudomonas cichorii in complex with d-talitol
    28% identity, 86% coverage of query (74.3 bits)

LR3E_METSD / A0A172U6X0 L-ribulose 3-epimerase; LRE; MetLRE; EC 5.1.3.31 from Methylomonas sp. (strain DH-1) (see paper)
    27% identity, 85% coverage of query (73.9 bits)

4ytrC Crystal structure of d-tagatose 3-epimerase c66s from pseudomonas cichorii in complex with 1-deoxy l-tagatose
    28% identity, 86% coverage of query (73.9 bits)

4ytqC Crystal structure of d-tagatose 3-epimerase c66s from pseudomonas cichorii in complex with 1-deoxy d-tagatose
    28% identity, 86% coverage of query (73.9 bits)

7cj7B Crystal structure of homo dimeric d-allulose 3-epimerase from methylomonas sp. In complex with l-tagatose
    27% identity, 85% coverage of query (73.9 bits)

7cj7A Crystal structure of homo dimeric d-allulose 3-epimerase from methylomonas sp. In complex with l-tagatose
    27% identity, 85% coverage of query (73.9 bits)

7cj6A Crystal structure of homo dimeric d-allulose 3-epimerase from methylomonas sp. In complex with d-allulose
    27% identity, 85% coverage of query (73.9 bits)

7cj5A / A0A172U6X0 Crystal structure of homo dimeric d-allulose 3-epimerase from methylomonas sp. In complex with d-fructose (see paper)
    27% identity, 85% coverage of query (73.6 bits)

4pglA Crystal structure of engineered d-tagatose 3-epimerase pcdte-ils6
    28% identity, 86% coverage of query (73.6 bits)

4pfhA / O50580 Crystal structure of engineered d-tagatose 3-epimerase pcdte-idf8 (see paper)
    27% identity, 91% coverage of query (71.6 bits)

YhfP / b4474 fructoselysine 3-epimerase (EC 5.1.3.41) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
frlC / P45541 fructoselysine 3-epimerase (EC 5.1.3.41) from Escherichia coli (strain K12) (see 2 papers)
FRLC_ECOLI / P45541 Fructoselysine 3-epimerase; EC 5.1.3.41 from Escherichia coli (strain K12) (see paper)
    23% identity, 86% coverage of query (50.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory