Searching for up to 100 curated homologs for 15560 FitnessBrowser__Keio:15560 (468 a.a.)
Found high-coverage hits (≥70%) to 66 curated proteins.
Removed hits that are identical to the query, leaving 65
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
DVU0030 / VIMSS7454265 DVU0030 regulator of Amino acid transport from Desulfohalobium retbaense DSM 5692
36% identity, 99% coverage of query (304 bits)
DVU0030 / VIMSS8508254 DVU0030 regulator of Amino acid transport from Desulfovibrio salexigens DSM 2638
34% identity, 99% coverage of query (304 bits)
YjiR / b4340 fused putative DNA-binding transcriptional regulator/putative aminotransferase YjiR from Escherichia coli K-12 substr. MG1655 (see 5 papers)
yjiR / RF|NP_418760 uncharacterized HTH-type transcriptional regulator yjiR from Escherichia coli K12 (see 2 papers)
35% identity, 99% coverage of query (300 bits)
DVU0030 / VIMSS8501445 DVU0030 regulator of Amino acid transport from Desulfovibrio vulgaris str. Miyazaki F
35% identity, 99% coverage of query (295 bits)
DVU0030 / VIMSS7650531 DVU0030 regulator of Amino acid transport from Desulfovibrio magneticus RS-1
36% identity, 99% coverage of query (292 bits)
DVU0030 / VIMSS393253 DVU0030 regulator of Amino acid transport from Desulfovibrio desulfuricans G20
33% identity, 99% coverage of query (283 bits)
DVU0030 / VIMSS408289 DVU0030 regulator of Amino acid transport from Desulfovibrio vulgaris Hildenborough
36% identity, 98% coverage of query (275 bits)
DVU0030 / VIMSS7533539 DVU0030 regulator of Amino acid transport from Desulfomicrobium baculatum DSM 4028
35% identity, 99% coverage of query (273 bits)
AZOBR_RS06555 Branched-chain-amino-acid transaminase (EC 2.6.1.42) from Azospirillum brasilense Sp245
32% identity, 80% coverage of query (184 bits)
Build an alignment for 15560 and 9 homologs with ≥ 30% identity
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YdfD/YisV / VIMSS6924547 YdfD/YisV regulator of Metabolite transport (activator/repressor) from Paenibacillus sp. JDR-2
27% identity, 93% coverage of query (181 bits)
ARAT1_THELN / H3ZPL1 Aromatic-amino-acid aminotransferase 1; ARAT-I; AROAT; EC 2.6.1.57 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see paper)
29% identity, 80% coverage of query (169 bits)
A0A060PQX5 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Thermococcus sp. (see paper)
29% identity, 80% coverage of query (166 bits)
O57946 kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Pyrococcus horikoshii (see paper)
26% identity, 80% coverage of query (162 bits)
3aovA / O57946 Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with plp
26% identity, 80% coverage of query (162 bits)
3wx9A Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with pmp, gla, 4ad, 2og, glu and kya
26% identity, 80% coverage of query (162 bits)
3av7A Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with pmp, kyn as substrates and kya as products
26% identity, 80% coverage of query (162 bits)
3aowC Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with akg
26% identity, 80% coverage of query (162 bits)
1wstA / Q9V2W5 Crystal structure of multiple substrate aminotransferase (msat) from thermococcus profundus
29% identity, 80% coverage of query (158 bits)
YdfD/YisV / VIMSS63013 YdfD/YisV regulator of Metabolite transport (activator/repressor) from Bacillus halodurans C-125
25% identity, 99% coverage of query (157 bits)
lysN / Q5SL82 L-2-aminoadipate aminotransferase monomer (EC 2.6.1.39) from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
30% identity, 80% coverage of query (155 bits)
LYSN_THET2 / Q72LL6 2-aminoadipate transaminase; 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT; EC 2.6.1.39 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 3 papers)
Q72LL6 2-aminoadipate transaminase (EC 2.6.1.39) from Thermus thermophilus (see paper)
2zyjA / Q72LL6 Crystal structure of lysn, alpha-aminoadipate aminotransferase (complexed with n-(5'-phosphopyridoxyl)-l-glutamate), from thermus thermophilus hb27 (see paper)
30% identity, 80% coverage of query (155 bits)
3cbfA Crystal structure of lysn, alpha-aminoadipate aminotransferase, from thermus thermophilus hb27
30% identity, 80% coverage of query (155 bits)
2egyA Crystal structure of lysn, alpha-aminoadipate aminotransferase (substrate free form), from thermus thermophilus hb27
30% identity, 80% coverage of query (155 bits)
BWI76_RS24235 Branched-chain-amino-acid transaminase (EC 2.6.1.42) from Klebsiella michiganensis M5al
28% identity, 79% coverage of query (150 bits)
2z1yA Crystal structure of lysn, alpha-aminoadipate aminotransferase (complexed with n-(5'-phosphopyridoxyl)-l-leucine), from thermus thermophilus hb27
31% identity, 77% coverage of query (148 bits)
Ac3H11_1015 Aromatic-amino-acid aminotransferase (EC 2.6.1.57) from Acidovorax sp. GW101-3H11
27% identity, 77% coverage of query (144 bits)
Ac3H11_1358 L-leucine transaminase; L-isoleucine transaminase (EC 2.6.1.42) from Acidovorax sp. GW101-3H11
29% identity, 76% coverage of query (140 bits)
NORG_STAA8 / Q2G1P1 HTH-type transcriptional regulator NorG from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
25% identity, 93% coverage of query (139 bits)
2zc0A / Q9C4M4 Crystal structure of an archaeal alanine:glyoxylate aminotransferase (see paper)
28% identity, 78% coverage of query (136 bits)
1vp4A / Q9X0L5 Crystal structure of a putative aminotransferase (tm1131) from thermotoga maritima msb8 at 1.82 a resolution
27% identity, 81% coverage of query (131 bits)
YdfD/YisV / VIMSS822665 YdfD/YisV regulator of Metabolite transport (activator/repressor) from Bacillus clausii KSM-K16
24% identity, 91% coverage of query (126 bits)
8tn3A / Q643B9 Structure of s. Hygroscopicus aminotransferase mppq complexed with pyridoxamine 5'-phosphate (pmp) (see paper)
28% identity, 76% coverage of query (114 bits)
TAUR_RHOCB / D5AKX9 HTH-type transcriptional regulator TauR from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) (see paper)
27% identity, 91% coverage of query (110 bits)
A0A1D8PPA8 aromatic-amino-acid transaminase (EC 2.6.1.57) from Candida albicans (see paper)
24% identity, 77% coverage of query (110 bits)
PdxR / VIMSS3789276 PdxR regulator of Pyridoxine biosynthesis, effector Pyridoxal-5-phosphate from Streptococcus gordonii str. Challis substr. CH1
28% identity, 81% coverage of query (107 bits)
Desal_3745 / VIMSS8508801 Desal_3745 regulator of Metabolite transport from Desulfovibrio salexigens DSM 2638
25% identity, 92% coverage of query (107 bits)
PdxR / VIMSS5804477 PdxR regulator of Pyridoxine biosynthesis, effector Pyridoxal-5-phosphate from Streptococcus equi subsp. zooepidemicus MGCS10565
26% identity, 82% coverage of query (105 bits)
2vgzA Crystal structure of human kynurenine aminotransferase ii
25% identity, 78% coverage of query (104 bits)
2xh1A Crystal structure of human kat ii-inhibitor complex
26% identity, 79% coverage of query (104 bits)
AADAT / Q8N5Z0 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (EC 2.6.1.7; EC 2.6.1.39) from Homo sapiens (see 5 papers)
AADAT_HUMAN / Q8N5Z0 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; KAT/AadAT; 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; Alpha-aminoadipate aminotransferase; AadAT; Glycine transaminase AADAT; Kynurenine aminotransferase II; Kynurenine--glyoxylate transaminase AADAT; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; Kynurenine--oxoglutarate transaminase II; Methionine--glyoxylate transaminase AADAT; EC 2.6.1.39; EC 2.6.1.4; EC 2.6.1.63; EC 2.6.1.7; EC 2.6.1.73 from Homo sapiens (Human) (see 4 papers)
Q8N5Z0 2-aminoadipate transaminase (EC 2.6.1.39); kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Homo sapiens (see 16 papers)
26% identity, 79% coverage of query (103 bits)
5tf5A Crystal structure of human kat-2 in complex with a reversible inhibitor
26% identity, 79% coverage of query (103 bits)
2r2nA The crystal structure of human kynurenine aminotransferase ii in complex with kynurenine
26% identity, 79% coverage of query (103 bits)
6t8qA Hkatii in complex with ligand (2r)-n-benzyl-1-[6-methyl-5-(oxan-4-yl)- 7-oxo-6h,7h-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrrolidine-2- carboxamide
26% identity, 79% coverage of query (103 bits)
4gdyB / Q8N5Z0 Kynurenine aminotransferase ii inhibitors
26% identity, 79% coverage of query (102 bits)
4gebA Kynurenine aminotransferase ii inhibitors
26% identity, 79% coverage of query (102 bits)
4ge9A Kynurenine aminotransferase ii inhibitors
26% identity, 79% coverage of query (102 bits)
4ge7A Kynurenine aminotransferase ii inhibitors
26% identity, 79% coverage of query (102 bits)
4ge4A Kynurenine aminotransferase ii inhibitors
25% identity, 78% coverage of query (102 bits)
3ue8A Kynurenine aminotransferase ii inhibitors
25% identity, 79% coverage of query (102 bits)
AADAT_MOUSE / Q9WVM8 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; KAT/AadAT; 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; Alpha-aminoadipate aminotransferase; AadAT; Glycine transaminase AADAT; Kynurenine aminotransferase II; Kynurenine--glyoxylate transaminase AADAT; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; Kynurenine--oxoglutarate transaminase II; Methionine--glyoxylate transaminase AADAT; EC 2.6.1.39; EC 2.6.1.4; EC 2.6.1.63; EC 2.6.1.7; EC 2.6.1.73 from Mus musculus (Mouse) (see paper)
Q9WVM8 2-aminoadipate transaminase (EC 2.6.1.39); kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Mus musculus (see paper)
24% identity, 78% coverage of query (99.0 bits)
1v2eA / Q75WK2 Crystal structure of t.Th hb8 glutamine aminotransferase complex with a-keto-g-methylthiobutyrate (see paper)
27% identity, 77% coverage of query (98.6 bits)
BAD06364.1 aminotransferase from Thermus thermophilus (see paper)
27% identity, 77% coverage of query (98.6 bits)
1v2fA Crystal structure of t.Th hb8 glutamine aminotransferase complex with 3-phenylpropionate
27% identity, 77% coverage of query (98.6 bits)
Aadat / Q64602 α-aminoadipate aminotransferase subunit (EC 2.6.1.39) from Rattus norvegicus (see paper)
AADAT_RAT / Q64602 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; KAT/AadAT; 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; Alpha-aminoadipate aminotransferase; AadAT; Glycine transaminase AADAT; Kynurenine aminotransferase II; Kynurenine--glyoxylate transaminase AADAT; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; Kynurenine--oxoglutarate transaminase II; Methionine--glyoxylate transaminase AADAT; EC 2.6.1.39; EC 2.6.1.4; EC 2.6.1.63; EC 2.6.1.7; EC 2.6.1.73 from Rattus norvegicus (Rat) (see paper)
Q64602 2-aminoadipate transaminase (EC 2.6.1.39); kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Rattus norvegicus (see 2 papers)
25% identity, 79% coverage of query (98.2 bits)
6t8pA Hkatii in complex with ligand (2r)-n-benzyl-1-[6-methyl-5-(oxan-4-yl)- 7-oxo-6h,7h-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrrolidine-2- carboxamide
25% identity, 79% coverage of query (97.8 bits)
7zlaB / Q5WKW3 Cryo-em structure of holo-pdxr from bacillus clausii bound to its target DNA in the half-closed conformation (see paper)
25% identity, 92% coverage of query (96.7 bits)
tdiD / A7XRY8 L-tryptophan:phenylpyruvate aminotransferase (EC 2.6.1.28) from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (see 3 papers)
TDID_EMENI / A7XRY8 Aminotransferase tdiD; Terrequinone biosynthesis protein D; EC 2.6.1.28 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 5 papers)
A7XRY8 tryptophan-phenylpyruvate transaminase (EC 2.6.1.28) from Aspergillus nidulans (see 2 papers)
24% identity, 77% coverage of query (95.5 bits)
PTSJ_SALTY / P40193 Vitamin B6 salvage pathway transcriptional repressor PtsJ; HTH-type transcriptional regulatory protein PtsJ from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
28% identity, 89% coverage of query (94.0 bits)
GABR_BACSU / P94426 HTH-type transcriptional regulatory protein GabR from Bacillus subtilis (strain 168) (see 2 papers)
24% identity, 86% coverage of query (93.6 bits)
PdxR / VIMSS101492 PdxR regulator of Pyridoxine biosynthesis, effector Pyridoxal-5-phosphate from Streptococcus pyogenes M1 GAS
26% identity, 80% coverage of query (92.4 bits)
AATR3_SCHPO / Q9Y7S6 Aromatic amino acid aminotransferase C569.07; EC 2.6.1.57 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
25% identity, 72% coverage of query (89.7 bits)
PdxR / VIMSS295699 PdxR regulator of Pyridoxine biosynthesis, effector Pyridoxal-5-phosphate from Streptococcus mutans UA159
24% identity, 93% coverage of query (89.0 bits)
AATR2_SCHPO / O94570 Aromatic amino acid aminotransferase C1773.13; EC 2.6.1.57 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
24% identity, 79% coverage of query (86.3 bits)
7zn5B / Q5WKW3 Cryo-em structure of holo-pdxr from bacillus clausii bound to its target DNA in the closed conformation, c2 symmetry. (see paper)
24% identity, 92% coverage of query (85.9 bits)
2o0rA / P9WPZ5 The three-dimensional structure of n-succinyldiaminopimelate aminotransferase from mycobacterium tuberculosis (see paper)
27% identity, 74% coverage of query (72.4 bits)
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