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Searching for up to 100 curated homologs for 15733 FitnessBrowser__Keio:15733 (548 a.a.)

Found high-coverage hits (≥70%) to 11 curated proteins.

Removed hits that are identical to the query, leaving 10

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

FumB / b4122 fumarase B (EC 4.2.1.2; EC 4.2.1.81) from Escherichia coli K-12 substr. MG1655 (see 20 papers)
fumB / P14407 fumarase B (EC 4.2.1.2; EC 4.2.1.81) from Escherichia coli (strain K12) (see 21 papers)
FUMB_ECOLI / P14407 Fumarate hydratase class I, anaerobic; D-tartrate dehydratase; Fumarase B; EC 4.2.1.2; EC 4.2.1.81 from Escherichia coli (strain K12) (see 3 papers)
P14407 fumarate hydratase (EC 4.2.1.2); (S)-2-methylmalate dehydratase (EC 4.2.1.34) from Escherichia coli (see paper)
fumB / GB|AAC77083.1 fumarate hydratase class I, anaerobic; EC 4.2.1.2 from Escherichia coli K12 (see 5 papers)
FumB / EW|b4122 anaerobic class I fumarate hydratase (fumarase B) from Escherichia coli K12 (see 3 papers)
    90% identity, 100% coverage of query (1028 bits)

Q8X999 fumarate hydratase (EC 4.2.1.2) from Escherichia coli (see paper)
    68% identity, 99% coverage of query (813 bits)

FUM2_LEIMA / E9AE57 Fumarate hydratase 2; Fumarase 2; LmFH-2; EC 4.2.1.2 from Leishmania major (see 3 papers)
    64% identity, 98% coverage of query (712 bits)

6uoiA Crystal structure of cytosolic fumarate hydratase from leishmania major in a complex with malonate
    64% identity, 98% coverage of query (711 bits)

6unzA / E9AE57 Crystal structure of cytosolic fumarate hydratase from leishmania major (see paper)
    64% identity, 98% coverage of query (710 bits)

6msnA Crystal structure of cytosolic fumarate hydratase from leishmania major in a complex with inhibitor thiomalate
    65% identity, 97% coverage of query (709 bits)

6uqnB Crystal structure of r173a variant of cytosolic fumarate hydratase from leishmania major in a complex with fumarate and s-malate
    65% identity, 97% coverage of query (706 bits)

6msoA / Q4QAU9 Crystal structure of mitochondrial fumarate hydratase from leishmania major in a complex with inhibitor thiomalate (see paper)
    61% identity, 95% coverage of query (681 bits)

FUM1_LEIMA / Q4QAU9 Fumarate hydratase 1, mitochondrial; Fumarase 1; LmFH-1; EC 4.2.1.2 from Leishmania major (see 2 papers)
    61% identity, 95% coverage of query (681 bits)

Q141Z6 fumarate hydratase (EC 4.2.1.2); (S)-2-methylmalate dehydratase (EC 4.2.1.34) from Paraburkholderia xenovorans (see paper)
    32% identity, 84% coverage of query (199 bits)

Build an alignment

Build an alignment for 15733 and 10 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory