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Searching for up to 100 curated homologs for 15852 b1734 cryptic phospho-beta-glucosidase, NAD(P)-binding (NCBI) (450 a.a.)

Found high-coverage hits (≥70%) to 46 curated proteins.

Removed hits that are identical to the query, leaving 45

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

BAB35863.1 6-P-β-glucosidase (ChbF;ECs2440) (EC 3.2.1.86) (see protein)
    99% identity, 100% coverage of query (920 bits)

CAA90288.1 6-P-β-glucosidase (CelF;CelD;LicH;BSU38560) (EC 3.2.1.86) (see protein)
    54% identity, 98% coverage of query (478 bits)

AHL67642.1 6-P-β-glucosidase (LicH;Gan4C) (EC 3.2.1.86) (see protein)
    53% identity, 98% coverage of query (475 bits)

5c3mB / W8R9V4 Crystal structure of gan4c, a gh4 6-phospho-glucosidase from geobacillus stearothermophilus
    51% identity, 97% coverage of query (434 bits)

AAD36356.1 6-P-β-glucosidase (BglT;TM1281) (EC 3.2.1.86) (see protein)
    34% identity, 96% coverage of query (221 bits)

1up7A / Q9X108 Structure of the 6-phospho-beta glucosidase from thermotoga maritima at 2.4 angstrom resolution in the tetragonal form with NAD and glucose-6-phosphate (see paper)
    33% identity, 96% coverage of query (216 bits)

1up6A Structure of the 6-phospho-beta glucosidase from thermotoga maritima at 2.55 angstrom resolution in the tetragonal form with manganese, NAD+ and glucose-6-phosphate
    33% identity, 96% coverage of query (215 bits)

Build an alignment

Build an alignment for 15852 and 7 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

6dvvA / Q9AGA6 2.25 angstrom resolution crystal structure of 6-phospho-alpha- glucosidase from klebsiella pneumoniae in complex with NAD and mn2+. (see paper)
    28% identity, 97% coverage of query (176 bits)

AGLB_KLEPN / Q9AGA6 6-phospho-alpha-glucosidase; EC 3.2.1.122 from Klebsiella pneumoniae (see 2 papers)
Q9AGA6 maltose-6'-phosphate glucosidase (EC 3.2.1.122) from Klebsiella pneumoniae (see 3 papers)
AAK01457.1 6-phospho-α-glucosidase (AglB) (EC 3.2.1.122) (see protein)
    27% identity, 97% coverage of query (174 bits)

PAGL_CLOAB / Q97DP6 Phospho-alpha-glucosidase PagL; EC 3.2.1.- from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) (see paper)
AAK81356.1 6-phospho-α-glucosidase (Pagl;CAC3426) (EC 3.2.1.122) (see protein)
    30% identity, 96% coverage of query (172 bits)

6wbtA 2.52 angstrom resolution crystal structure of 6-phospho-alpha- glucosidase from gut microorganisms in complex with NAD and glucose- 6-phosphate
    27% identity, 97% coverage of query (171 bits)

MALH_CLOAB / Q97LM4 Maltose-6'-phosphate glucosidase MalH; 6-phospho-alpha-glucosidase; 6-phospho-glucosidase; Maltose-6-phosphate hydrolase; EC 3.2.1.122 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) (see paper)
AAK78512.1 6-phospho-α-glucosidase (MalH;GlvA;CAC0533) (EC 3.2.1.122) (see protein)
    26% identity, 97% coverage of query (166 bits)

O06901 maltose-6'-phosphate glucosidase (EC 3.2.1.122) from Fusobacterium mortiferum (see 2 papers)
AAB63015.1 6-P-α-glucosidase (MalH) (EC 3.2.1.122) (see protein)
malH / GI|2145152 maltose-6'-phosphate glucosidase; EC 3.2.1.122 from Fusobacterium mortiferum (see 3 papers)
    26% identity, 97% coverage of query (162 bits)

PAGL_LEPBD / C7NB67 6-phospho-alpha-glucosidase; EC 3.2.1.- from Leptotrichia buccalis (strain ATCC 14201 / DSM 1135 / JCM 12969 / NCTC 10249 / C-1013-b) (see paper)
    26% identity, 97% coverage of query (162 bits)

1u8xX / P54716 Crystal structure of glva from bacillus subtilis, a metal-requiring, NAD-dependent 6-phospho-alpha-glucosidase (see paper)
    26% identity, 97% coverage of query (152 bits)

malA / P54716 maltose-6′-phosphate glucosidase (EC 3.2.1.122) from Bacillus subtilis (strain 168) (see 7 papers)
GLVA_BACSU / P54716 Maltose-6'-phosphate glucosidase; 6-phospho-alpha-D-glucosidase; 6-phosphoryl-O-alpha-D-glucopyranosyl:phosphoglucohydrolase; EC 3.2.1.122 from Bacillus subtilis (strain 168) (see 3 papers)
P54716 maltose-6'-phosphate glucosidase (EC 3.2.1.122) from Bacillus subtilis (see 2 papers)
BAA09103.1 6-P-α-glucosidase (GlvA;Glv-1;GlgG;BSU08180) (EC 3.2.1.122) (see protein)
glvA / GB|BAA09103.1 maltose-6'-phosphate glucosidase; EC 3.2.1.122 from Bacillus subtilis (see 7 papers)
    26% identity, 97% coverage of query (152 bits)

6vc6B 2.1 angstrom resolution crystal structure of 6-phospho-alpha- glucosidase from gut microorganisms in complex with NAD and mn2+
    27% identity, 97% coverage of query (140 bits)

EFF38781.1 α-galactosidase (AgaA;EfmE980_0223) (EC 3.2.1.22) (see protein)
    28% identity, 82% coverage of query (124 bits)

AGG11047.1 α-galactosidase (MelA;BmelA) (EC 3.2.1.22) (see protein)
    26% identity, 97% coverage of query (121 bits)

MelA / b4119 α-galactosidase (EC 3.2.1.22) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
melA / P06720 α-galactosidase (EC 3.2.1.22) from Escherichia coli (strain K12) (see 7 papers)
AGAL_ECOLI / P06720 Alpha-galactosidase; Melibiase; EC 3.2.1.22 from Escherichia coli (strain K12) (see paper)
AAA97019.1 α-galactosidase A (MelA;b4119) (EC 3.2.1.22) (see protein)
    26% identity, 98% coverage of query (121 bits)

AGAL_BACSU / O34645 Alpha-galactosidase; Melibiase; EC 3.2.1.22 from Bacillus subtilis (strain 168) (see paper)
AAC00383.1 α-galactosidase (MelA;BSU30300) (EC 3.2.1.22) (see protein)
    27% identity, 96% coverage of query (120 bits)

Q9KAQ9 alpha-galactosidase (EC 3.2.1.22) from Alkalihalobacillus halodurans (see paper)
BAB05947.1 α-galactosidase (MelA;BH2228) (Mel4A) (EC 3.2.1.22) (see protein)
    26% identity, 96% coverage of query (119 bits)

CAC49967.1 α-galactosidase (MelA;AgaL1;SMb21648) (EC 3.2.1.22) (see protein)
    27% identity, 99% coverage of query (119 bits)

BAB20428.1 α-galactosidase (MelA) (EC 3.2.1.22) (see protein)
    25% identity, 98% coverage of query (114 bits)

AAL23122.1 α-galactosidase (MelA;STM4298) (EC 3.2.1.22) (see protein)
    25% identity, 98% coverage of query (114 bits)

PALH_ERWRD / Q9AI65 Alpha-glucosidase; EC 3.2.1.20 from Erwinia rhapontici (Pectobacterium rhapontici) (see 2 papers)
Q9AI65 alpha-glucosidase (EC 3.2.1.20); 6-phospho-beta-glucosidase (EC 3.2.1.86) from Erwinia rhapontici (see paper)
    25% identity, 96% coverage of query (105 bits)

AAK28734.1 α-glucosidase (PalH) (EC 3.2.1.20) (see protein)
    25% identity, 96% coverage of query (105 bits)

AAE36426.1 palatinase (EC 3.2.1.-) (see protein)
    25% identity, 96% coverage of query (105 bits)

CAC49962.1 SMb21643 (AgaL2) (EC 3.2.1.22) (see protein)
    23% identity, 100% coverage of query (98.6 bits)

LPLD_THESW / I3VRU1 Alpha-galacturonidase; EC 3.2.1.67 from Thermoanaerobacterium saccharolyticum (strain DSM 8691 / JW/SL-YS485) (see paper)
    25% identity, 97% coverage of query (92.4 bits)

LPLD_LACP7 / A9KTB9 Alpha-galacturonidase; EC 3.2.1.67 from Lachnoclostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) (Clostridium phytofermentans) (see paper)
    25% identity, 96% coverage of query (89.0 bits)

LPLD_BACSU / P39130 Alpha-galacturonidase; EC 3.2.1.67 from Bacillus subtilis (strain 168) (see paper)
CAB12532.1 α-galacturonidase (LplD;BSU07130) (EC 3.2.1.67) (see protein)
    24% identity, 95% coverage of query (88.6 bits)

3fefA / P39130 Crystal structure of putative glucosidase lpld from bacillus subtilis
    24% identity, 95% coverage of query (88.6 bits)

AGLA_THEMA / O33830 Alpha-glucosidase; Maltase; EC 3.2.1.20 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 2 papers)
O33830 alpha-glucosidase (EC 3.2.1.20) from Thermotoga maritima (see paper)
AAD36897.1 α-glucosidase (AglA;TM1834) (EC 3.2.1.20) (see protein)
    23% identity, 94% coverage of query (81.3 bits)

1obbA / O33830 Alpha-glucosidase a, agla, from thermotoga maritima in complex with maltose and NAD+ (see paper)
    23% identity, 94% coverage of query (81.3 bits)

aglA / CAA04524.1 alpha-glucosidase from Thermotoga maritima (see paper)
    23% identity, 93% coverage of query (79.7 bits)

3u95A Crystal structure of a putative alpha-glucosidase from thermotoga neapolitana
    24% identity, 86% coverage of query (79.0 bits)

1vjtA / Q9WZL1 Crystal structure of alpha-glucosidase (tm0752) from thermotoga maritima at 2.50 a resolution
    22% identity, 82% coverage of query (74.7 bits)

6kcxA Crystal structure of citrate complex of alpha-glucuronidase (tm0752) from thermotoga maritima
    22% identity, 82% coverage of query (74.7 bits)

AAD35834.1 α-glucuronidase (TM0752) (Agu4B) (EC 3.2.1.139) (see protein)
    22% identity, 82% coverage of query (74.3 bits)

7ctmA Crystal structure of thermotoga maritima alpha-glucuronidase (tm0752) in complex with nadh and d-glucuronic acid
    22% identity, 82% coverage of query (74.3 bits)

7br4A Structure of deletion mutant of alpha-glucuronidase (tm0752) from thermotoga maritima
    22% identity, 82% coverage of query (74.3 bits)

AGLA_THENE / O86960 Alpha-glucosidase; Maltase; EC 3.2.1.20 from Thermotoga neapolitana (see paper)
    24% identity, 94% coverage of query (72.8 bits)

CAA08868.1 α-glucosidase (AglA) (EC 3.2.1.20) (see protein)
    24% identity, 93% coverage of query (71.2 bits)

agu4A / Q9WYR5 α-glucuronidase (EC 3.2.1.139) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
AAD35519.1 α-glucuronidase (Agu;TM0434) (Agu4A) (EC 3.2.1.139) (see protein)
    25% identity, 80% coverage of query (70.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory