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Searching for up to 100 curated homologs for 15920 FitnessBrowser__Keio:15920 (374 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

Removed hits that are identical to the query, leaving 17

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

cntA / D0C9N6 carnitine monooxygenase oxygenase component (EC 1.14.13.239) from Acinetobacter baumannii (strain ATCC 19606 / DSM 30007 / JCM 6841 / CCUG 19606 / CIP 70.34 / NBRC 109757 / NCIMB 12457 / NCTC 12156 / 81) (see paper)
CNTA_ACIB2 / D0C9N6 Carnitine monooxygenase oxygenase subunit; Carnitine monooxygenase alpha subunit; EC 1.14.13.239 from Acinetobacter baumannii (strain ATCC 19606 / DSM 30007 / JCM 6841 / CCUG 19606 / CIP 70.34 / NBRC 109757 / NCIMB 12457 / NCTC 12156 / 81) (see paper)
D0C9N6 carnitine monooxygenase (subunit 2/2) (EC 1.14.13.239) from Acinetobacter baumannii (see paper)
    74% identity, 97% coverage of query (586 bits)

yeaW / F0KFI5 carnitine monooxygenase α subunit (EC 1.14.13.239) from Acinetobacter calcoaceticus (strain PHEA-2) (see 2 papers)
CNTA_ACICP / F0KFI5 Carnitine monooxygenase oxygenase subunit; Carnitine monooxygenase alpha subunit; EC 1.14.13.239 from Acinetobacter calcoaceticus (strain PHEA-2) (see paper)
    74% identity, 97% coverage of query (583 bits)

6y9cA / D0C9N6 The structure of a quaternary ammonium rieske monooxygenase reveals insights into carnitine oxidation by gut microbiota and inter-subunit electron transfer (see paper)
    74% identity, 97% coverage of query (581 bits)

6zgpA Crystal structure of the quaternary ammonium rieske monooxygenase cnta in complex with inhibitor mmv12 (mmv020670)
    73% identity, 97% coverage of query (572 bits)

6y8sA Crystal structure of the quaternary ammonium rieske monooxygenase cnta in complex with substrate gamma-butyrobetaine
    71% identity, 97% coverage of query (549 bits)

6y8jA / A0A059ZPP5 Crystal structure of the apo form of a quaternary ammonium rieske monooxygenase cnta (see paper)
    70% identity, 97% coverage of query (537 bits)

Q8RXB4 choline monooxygenase (EC 1.14.15.7) from Atriplex prostrata (see paper)
    30% identity, 95% coverage of query (152 bits)

Q7XZR0 choline monooxygenase (EC 1.14.15.7) from Atriplex nummularia (see paper)
    31% identity, 95% coverage of query (150 bits)

CMO / O04121 choline monooxygenase monomer (EC 1.14.15.7) from Spinacia oleracea (see 4 papers)
CHMO_SPIOL / O04121 Choline monooxygenase, chloroplastic; EC 1.14.15.7 from Spinacia oleracea (Spinach) (see paper)
    30% identity, 95% coverage of query (142 bits)

Q93XE1 choline monooxygenase (EC 1.14.15.7) from Amaranthus tricolor (see paper)
    30% identity, 95% coverage of query (141 bits)

Build an alignment

Build an alignment for 15920 and 10 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

O22553 choline monooxygenase (EC 1.14.15.7) from Beta vulgaris (see paper)
    29% identity, 95% coverage of query (140 bits)

Q5MAD4 choline monooxygenase (EC 1.14.15.7) from Salicornia europaea (see paper)
    29% identity, 95% coverage of query (140 bits)

CMO / B5UAE1 peroxisomal choline monooxygenase (EC 1.1.99.1) from Hordeum vulgare (see paper)
B5UAE1 choline monooxygenase (EC 1.14.15.7) from Hordeum vulgare (see paper)
    29% identity, 93% coverage of query (138 bits)

B8B239 choline monooxygenase (EC 1.14.15.7) from Oryza sativa (see paper)
    29% identity, 93% coverage of query (129 bits)

PfGW456L13_2740 Anthranilate 1,2-dioxygenase (deaminating, decarboxylating) (EC 1.14.12.1) from Pseudomonas fluorescens GW456-L13
    31% identity, 71% coverage of query (114 bits)

put2H / A0A0H3LKV3 putrescine 2-hydroxylase from Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) (see paper)
    26% identity, 94% coverage of query (87.0 bits)

Q0RXD9 3-ketosteroid 9alpha-monooxygenase (EC 1.14.15.30) from Rhodococcus jostii (see paper)
    22% identity, 70% coverage of query (56.2 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory