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Searching for up to 100 curated homologs for 16033 FitnessBrowser__Keio:16033 (328 a.a.)

Found high-coverage hits (≥70%) to 53 curated proteins.

Removed hits that are identical to the query, leaving 52

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

4d8uH / Q8ZNT7 Crystal structure of d-cysteine desulfhydrase from salmonella typhimurium at 3.3 a in monoclinic space group with 8 subunits in the asymmetric unit (see paper)
    90% identity, 100% coverage of query (610 bits)

Q8ZNT7 D-cysteine desulfhydrase (EC 4.4.1.15) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    90% identity, 100% coverage of query (609 bits)

4d9fA D-cysteine desulfhydrase from salmonella typhimurium complexed with d- cycloserine (dcs)
    90% identity, 100% coverage of query (609 bits)

4d9eA D-cysteine desulfhydrase from salmonella typhimurium complexed with l- cycloserine (lcs)
    90% identity, 100% coverage of query (609 bits)

4d9bA Pyridoxamine 5' phosphate (pmp) bound form of salmonella typhimurium d-cysteine desulfhydrase obtained after co-crystallization with d- cycloserine
    90% identity, 100% coverage of query (609 bits)

4d99A Salmonella typhimurium d-cysteine desulfhydrase with l-ser bound non- covalently at the active site
    90% identity, 100% coverage of query (609 bits)

4d97A Salmonella typhimurium d-cysteine desulfhydrase with d-ser bound at active site
    90% identity, 100% coverage of query (609 bits)

4d96A D-cysteine desulfhydrase from salmonella typhimurium complexed with 1- amino-1-carboxycyclopropane (acc)
    90% identity, 100% coverage of query (609 bits)

4d8wA Salmonella typhimurium d-cysteine desulfhydrase soaked with d-cys shows pyruvate bound 4 a away from active site
    90% identity, 100% coverage of query (609 bits)

cuyA / A3SQG3 L-cysteate sulfo-lyase (EC 4.4.1.25) from Roseovarius nubinhibens (strain ATCC BAA-591 / DSM 15170 / ISM) (see paper)
CUYA_ROSNI / A3SQG3 L-cysteate sulfo-lyase; EC 4.4.1.25 from Roseovarius nubinhibens (strain ATCC BAA-591 / DSM 15170 / ISM) (see paper)
    48% identity, 98% coverage of query (272 bits)

cuyA / Q5LL69 L-cysteate sulfo-lyase subunit (EC 4.4.1.25) from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (see 2 papers)
CUYA_RUEPO / Q5LL69 L-cysteate sulfo-lyase; EC 4.4.1.25 from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) (see paper)
    46% identity, 98% coverage of query (247 bits)

C5AQP6 D-cysteine desulfhydrase (EC 4.4.1.15) from Methylorubrum extorquens (see paper)
    44% identity, 98% coverage of query (236 bits)

B8R7S7 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Paraburkholderia terricola (see paper)
    38% identity, 98% coverage of query (211 bits)

O57809 L-serine ammonia-lyase (EC 4.3.1.17); D-Serine ammonia-lyase (EC 4.3.1.18) from Pyrococcus horikoshii (see paper)
1j0aA / O57809 Crystal structure analysis of the acc deaminase homologue (see paper)
    40% identity, 97% coverage of query (210 bits)

1j0bA Crystal structure analysis of the acc deaminase homologue complexed with inhibitor
    40% identity, 97% coverage of query (210 bits)

Q89XR6 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Bradyrhizobium japonicum (see paper)
    39% identity, 97% coverage of query (209 bits)

B8IP05 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Methylobacterium nodulans (see paper)
    38% identity, 97% coverage of query (209 bits)

B8R7S5 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Paraburkholderia silvatlantica (see paper)
    38% identity, 98% coverage of query (208 bits)

B2TBV3 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Paraburkholderia phytofirmans (see paper)
    38% identity, 98% coverage of query (207 bits)

B1M5C5 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Methylobacterium radiotolerans (see paper)
    39% identity, 97% coverage of query (207 bits)

B8R7S3 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Paraburkholderia phenoliruptrix (see paper)
    38% identity, 98% coverage of query (207 bits)

1tzmA Crystal structure of acc deaminase complexed with substrate analog b- chloro-d-alanine
    38% identity, 98% coverage of query (206 bits)

1tzkA Crystal structure of 1-aminocyclopropane-1-carboxylate-deaminase complexed with alpha-keto-butyrate
    38% identity, 98% coverage of query (206 bits)

1tzjA Crystal structure of 1-aminocyclopropane-1-carboxylate deaminase complexed with d-vinyl glycine
    38% identity, 98% coverage of query (206 bits)

1tz2A Crystal structure of 1-aminocyclopropane-1-carboyxlate deaminase complexed with acc
    38% identity, 98% coverage of query (206 bits)

A8VU64 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Sinorhizobium sp. BL3 (see paper)
    39% identity, 97% coverage of query (204 bits)

B8R7S2 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Paraburkholderia graminis (see paper)
    38% identity, 98% coverage of query (204 bits)

Q93AG0 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Rhizobium leguminosarum (see paper)
    38% identity, 97% coverage of query (203 bits)

B8R7S8 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Paraburkholderia unamae (see paper)
    38% identity, 98% coverage of query (203 bits)

B8R7S9 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Burkholderia vietnamiensis (see paper)
    38% identity, 98% coverage of query (203 bits)

B8R7R9 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Paraburkholderia caledonica (see paper)
    37% identity, 98% coverage of query (203 bits)

B4EJA6 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Burkholderia cenocepacia (see paper)
    39% identity, 98% coverage of query (202 bits)

B8R7S1 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Burkholderia cepacia (see paper)
    38% identity, 98% coverage of query (202 bits)

B2JYI5 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Paraburkholderia phymatum (see paper)
    38% identity, 98% coverage of query (201 bits)

1A1D_PSEUD / Q00740 1-aminocyclopropane-1-carboxylate deaminase; ACC deaminase; ACCD; EC 3.5.99.7 from Pseudomonas sp. (strain ACP) (see paper)
1rqxC / Q00740 Crystal structure of acc deaminase complexed with inhibitor (see paper)
    38% identity, 98% coverage of query (201 bits)

B8R7T2 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Paraburkholderia xenovorans (see paper)
    37% identity, 98% coverage of query (198 bits)

1A1D_PSEPU / Q5PWZ8 1-aminocyclopropane-1-carboxylate deaminase; ACC deaminase; ACCD; EC 3.5.99.7 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
Q5PWZ8 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Pseudomonas putida (see 2 papers)
    37% identity, 98% coverage of query (193 bits)

C3VP48 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Pseudomonas entomophila (see paper)
    37% identity, 98% coverage of query (191 bits)

D3U2Q8 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Trichoderma asperellum (see paper)
    35% identity, 97% coverage of query (179 bits)

G5AFQ7 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Phytophthora sojae (see paper)
    36% identity, 98% coverage of query (177 bits)

1f2dA / Q7M523 1-aminocyclopropane-1-carboxylate deaminase (see paper)
    34% identity, 97% coverage of query (162 bits)

Q7M523 1-aminocyclopropane-1-carboxylate deaminase; ACC deaminase; ACCD; EC 3.5.99.7 from Cyberlindnera saturnus (Yeast) (Williopsis saturnus)
    34% identity, 97% coverage of query (162 bits)

B2MWN0 D-cysteine desulfhydrase (EC 4.4.1.15) from Solanum lycopersicum (see paper)
    35% identity, 93% coverage of query (160 bits)

1j0eA Acc deaminase mutant reacton intermediate
    34% identity, 97% coverage of query (160 bits)

1j0dA Acc deaminase mutant complexed with acc
    34% identity, 97% coverage of query (160 bits)

DCYD1_ARATH / F4HYF3 Bifunctional D-cysteine desulfhydrase/1-aminocyclopropane-1-carboxylate deaminase, mitochondrial; 1-aminocyclopropane-1-carboxylic acid deaminase 1; AtACD1; AtD-CDes1; D-CDes1; D-CDES; EC 3.5.99.7; EC 4.4.1.15 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
F4HYF3 D-cysteine desulfhydrase (EC 4.4.1.15) from Arabidopsis thaliana (see paper)
    37% identity, 93% coverage of query (157 bits)

nocJ / Q5J1R2 nocardicin C-9'-epimerase (EC 5.1.1.14) from Nocardia uniformis subsp. tsuyamanensis (see paper)
NOCJ_NOCUT / Q5J1R2 Nocardicin C-9' epimerase; Nocardicin-A epimerase; EC 5.1.1.14 from Nocardia uniformis subsp. tsuyamanensis (see paper)
    30% identity, 94% coverage of query (79.0 bits)

Build an alignment

Build an alignment for 16033 and 47 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

A4VKI8 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) from Pseudomonas stutzeri (see paper)
    28% identity, 87% coverage of query (50.8 bits)

trpB / AAD29261.1 tryptophan synthase beta chain from Rhodobacter sphaeroides (see paper)
    26% identity, 84% coverage of query (46.2 bits)

6cgqA Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala
    22% identity, 96% coverage of query (44.3 bits)

6cgqB Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala
    23% identity, 96% coverage of query (43.9 bits)

6nmxA / A8HUA2 Threonine synthase from bacillus subtilis atcc 6633 with plp and appa (see paper)
    23% identity, 96% coverage of query (43.9 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory