Searching for up to 100 curated homologs for 16137 FitnessBrowser__Keio:16137 (468 a.a.)
Found high-coverage hits (≥70%) to 52 curated proteins.
Removed hits that are identical to the query, leaving 51
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
3fwnA / P00350 Dimeric 6-phosphogluconate dehydrogenase complexed with 6- phosphogluconate and 2'-monophosphoadenosine-5'-diphosphate (see paper)
100% identity, 100% coverage of query (951 bits)
3fwnB Dimeric 6-phosphogluconate dehydrogenase complexed with 6- phosphogluconate and 2'-monophosphoadenosine-5'-diphosphate
100% identity, 100% coverage of query (951 bits)
2zydA Dimeric 6-phosphogluconate dehydrogenase complexed with glucose
100% identity, 99% coverage of query (946 bits)
Q762L5 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Klebsiella pneumoniae (see paper)
96% identity, 100% coverage of query (925 bits)
gnd / AAA21136.1 phosphogluconate dehydrogenase from Escherichia coli (see paper)
94% identity, 100% coverage of query (913 bits)
gndA / P80859 6-phosphogluconate dehydrogenase (decarboxylating) (EC 1.1.1.44) from Bacillus subtilis (strain 168) (see paper)
6PGD_BACSU / P80859 6-phosphogluconate dehydrogenase, NADP(+)-dependent, decarboxylating; GNTZII; EC 1.1.1.44 from Bacillus subtilis (strain 168) (see paper)
P80859 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Bacillus subtilis (see paper)
70% identity, 100% coverage of query (691 bits)
2w90B Geobacillus stearothermophilus 6-phosphogluconate dehydrogenase with bound 6- phosphogluconate (see paper)
70% identity, 100% coverage of query (689 bits)
2iypB Product rup
68% identity, 100% coverage of query (661 bits)
2iypA Product rup
68% identity, 100% coverage of query (661 bits)
2iyoA Structural characterization of a bacterial 6pdh reveals aspects of specificity, mechanism and mode of inhibition
68% identity, 100% coverage of query (661 bits)
2iz1B / P96789 6pdh complexed with pex inhibitor synchrotron data (see paper)
68% identity, 100% coverage of query (660 bits)
P96789 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Lactococcus lactis (see paper)
68% identity, 100% coverage of query (660 bits)
P96789 6-phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 from Lactococcus lactis subsp. cremoris (strain MG1363)
68% identity, 100% coverage of query (660 bits)
7cb5B / A0A0H3KGN1 The 6-phosphogluconate dehydrogenase from staphylococcus aureus (6- phosphogluconate bound) (see paper)
67% identity, 99% coverage of query (657 bits)
7cb2A The 6-phosphogluconate dehydrogenase (NADP-bound) from staphylococcus aureus
67% identity, 99% coverage of query (656 bits)
P52208 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Synechocystis sp. (see paper)
59% identity, 100% coverage of query (553 bits)
6PGDH_BACSU / P12013 6-phosphogluconate dehydrogenase, NAD(+)-dependent, decarboxylating; EC 1.1.1.343 from Bacillus subtilis (strain 168) (see paper)
P12013 phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating) (EC 1.1.1.343) from Bacillus subtilis (see paper)
56% identity, 99% coverage of query (538 bits)
6PGD_AGGAC / P70718 6-phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 from Aggregatibacter actinomycetemcomitans (Actinobacillus actinomycetemcomitans) (Haemophilus actinomycetemcomitans) (see paper)
55% identity, 99% coverage of query (522 bits)
8i4qA / Q8NQI2 Crystal structure of 6-phosphogluconate dehydrogenase from corynebacterium glutamicum (see paper)
54% identity, 99% coverage of query (522 bits)
Q6NHC5 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Corynebacterium glutamicum (see paper)
53% identity, 99% coverage of query (508 bits)
6PGD_SHEEP / P00349 6-phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 from Ovis aries (Sheep) (see 2 papers)
54% identity, 100% coverage of query (499 bits)
Q9DCD0 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Mus musculus (see paper)
54% identity, 100% coverage of query (498 bits)
PGD / P52209 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) from Homo sapiens (see paper)
6PGD_HUMAN / P52209 6-phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 from Homo sapiens (Human)
P52209 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Homo sapiens (see 9 papers)
54% identity, 100% coverage of query (498 bits)
6PGD_RAT / P85968 6-phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 from Rattus norvegicus (Rat) (see paper)
P85968 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Rattus norvegicus (see 2 papers)
54% identity, 100% coverage of query (496 bits)
1pgqA Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism
54% identity, 99% coverage of query (496 bits)
1pgpA Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism
54% identity, 99% coverage of query (496 bits)
1pgoA Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism
54% identity, 99% coverage of query (496 bits)
1pgnA Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism
54% identity, 99% coverage of query (496 bits)
2jkvA / P52209 Structure of human phosphogluconate dehydrogenase in complex with NADPH at 2.53a
54% identity, 99% coverage of query (495 bits)
5uq9E Crystal structure of 6-phosphogluconate dehydrogenase with ((4r,5r)-5- (hydroxycarbamoyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl dihydrogen phosphate
54% identity, 99% coverage of query (495 bits)
6PGD1_ORYSJ / Q9LI00 6-phosphogluconate dehydrogenase, decarboxylating 1; OsG6PGH1; EC 1.1.1.44 from Oryza sativa subsp. japonica (Rice) (see paper)
Q9LI00 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Oryza sativa Japonica Group (see paper)
52% identity, 100% coverage of query (494 bits)
6PGD1_SPIOL / Q94KU1 6-phosphogluconate dehydrogenase, decarboxylating 1; EC 1.1.1.44 from Spinacia oleracea (Spinach) (see paper)
52% identity, 99% coverage of query (489 bits)
6PGD2_ARATH / Q9FWA3 6-phosphogluconate dehydrogenase, decarboxylating 2; EC 1.1.1.44 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9FWA3 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Arabidopsis thaliana (see 2 papers)
51% identity, 99% coverage of query (487 bits)
6PGD1_ARATH / Q9SH69 6-phosphogluconate dehydrogenase, decarboxylating 1, chloroplastic; EC 1.1.1.44 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9SH69 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Arabidopsis thaliana (see paper)
52% identity, 99% coverage of query (483 bits)
6PGD3_ARATH / Q9FFR3 6-phosphogluconate dehydrogenase, decarboxylating 3, chloroplastic; EC 1.1.1.44 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9FFR3 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Arabidopsis thaliana (see paper)
52% identity, 99% coverage of query (480 bits)
A0A0D1CRJ9 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Ustilago maydis (see paper)
53% identity, 97% coverage of query (480 bits)
6PGD2_SPIOL / Q94KU2 6-phosphogluconate dehydrogenase, decarboxylating 2, chloroplastic; EC 1.1.1.44 from Spinacia oleracea (Spinach) (see paper)
52% identity, 100% coverage of query (478 bits)
6PGD2_ORYSJ / Q2R480 6-phosphogluconate dehydrogenase, decarboxylating 2, chloroplastic; OsG6PGH2; EC 1.1.1.44 from Oryza sativa subsp. japonica (Rice)
51% identity, 99% coverage of query (478 bits)
P78812 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Schizosaccharomyces pombe (see paper)
SPBC660.16 / RF|NP_595095.1 phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 from Schizosaccharomyces pombe (see 3 papers)
52% identity, 97% coverage of query (477 bits)
P78812 6-phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
52% identity, 97% coverage of query (477 bits)
6PGD2_YEAST / P53319 6-phosphogluconate dehydrogenase, decarboxylating 2; EC 1.1.1.44 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P53319 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Saccharomyces cerevisiae (see paper)
51% identity, 97% coverage of query (471 bits)
6Pgd / CAD56883.1 6-phosphogluconic dehydrogenase from Bactrocera oleae (see paper)
52% identity, 99% coverage of query (465 bits)
GND1 6-phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 from Candida albicans (see paper)
51% identity, 100% coverage of query (453 bits)
6PGD1_YEAST / P38720 6-phosphogluconate dehydrogenase, decarboxylating 1; EC 1.1.1.44 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
P38720 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Saccharomyces cerevisiae (see 2 papers)
51% identity, 96% coverage of query (452 bits)
2p4qA / P38720 Crystal structure analysis of gnd1 in saccharomyces cerevisiae (see paper)
51% identity, 96% coverage of query (452 bits)
Q9WYR9 phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating) (EC 1.1.1.343); phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Thermotoga maritima (see 2 papers)
48% identity, 99% coverage of query (442 bits)
Q8IKT2 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Plasmodium falciparum (see paper)
6fqyA / Q8IKT2 Plasmodium falciparum 6-phosphogluconate dehydrogenase in its apo form, in complex with its cofactor NADP+ and in complex with its substrate 6-phosphogluconate (see paper)
46% identity, 99% coverage of query (427 bits)
6fqzA Plasmodium falciparum 6-phosphogluconate dehydrogenase in its apo form, in complex with its cofactor NADP+ and in complex with its substrate 6-phosphogluconate
46% identity, 99% coverage of query (427 bits)
8c79A / Q18L02 Crystal structure of leishmania donovani 6-phosphogluconate dehydrogenase complexed with NADPH (see paper)
40% identity, 99% coverage of query (338 bits)
Q6WAT5 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) (EC 1.1.1.44) from Trypanosoma cruzi (see paper)
38% identity, 99% coverage of query (333 bits)
6PGD_TRYBB / P31072 6-phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 from Trypanosoma brucei brucei (see paper)
37% identity, 96% coverage of query (312 bits)
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Lawrence Berkeley National Laboratory