Searching for up to 100 curated homologs for 16265 FitnessBrowser__Keio:16265 (489 a.a.)
Found high-coverage hits (≥70%) to 72 curated proteins.
Removed hits that are identical to the query, leaving 71
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
LYSP_LACLM / A2RNZ6 Lysine-specific permease LysP; Lysine transporter LysP from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
51% identity, 99% coverage of query (505 bits)
TC 2.A.3.1.18 / K7VV21 The lysine specific transporter, LysP of 488 aas and 12 TMSs from Lactococcus lactis subsp. cremoris UC509.9
51% identity, 100% coverage of query (503 bits)
HISP_LACLM / A2RI97 Histidine permease HisP from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
51% identity, 97% coverage of query (488 bits)
ROCE_BACSU / P39137 Amino-acid permease RocE from Bacillus subtilis (strain 168) (see paper)
TC 2.A.3.1.11 / P39137 L-Arginine permease, RocE from Bacillus subtilis (see 3 papers)
40% identity, 96% coverage of query (347 bits)
GAP2_CANAL / A0A1D8PK89 General amino-acid permease GAP2 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 6 papers)
TC 2.A.3.10.24 / Q59YT0 General amino and permease and transceptor, GAP2. Transports all amino acids including citruline and eight tested toxic amino acid derivatives from Candida albicans (see paper)
40% identity, 95% coverage of query (331 bits)
GABP_BACSU / P46349 Gamma-aminobutyric acid permease; GABA permease; 4-aminobutyrate permease; Gamma-aminobutyrate permease; Proline transporter GabP from Bacillus subtilis (strain 168) (see 3 papers)
TC 2.A.3.1.5 / P46349 β-alanine/γ-aminobutyrate/proline/3,4-dehydroproline:H+ symporter, GabP from Bacillus subtilis (see 4 papers)
gabP / AAC44641.1 gamma-aminobutyrate permease from Bacillus subtilis (see 2 papers)
41% identity, 90% coverage of query (328 bits)
gabP / AAB62306.1 GabP from Bacillus subtilis (see 4 papers)
41% identity, 90% coverage of query (327 bits)
MmuP / b0260 CP4-6 prophage; S-methyl-L-methionine transporter from Escherichia coli K-12 substr. MG1655 (see 3 papers)
mmuP / Q47689 CP4-6 prophage; S-methyl-L-methionine transporter from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.3.1.10 / Q47689 S-Methylmethionine permease, MmuP from Escherichia coli (see 3 papers)
40% identity, 89% coverage of query (327 bits)
CAN1_YEAST / P04817 Arginine permease CAN1; Canavanine resistance protein 1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 12 papers)
TC 2.A.3.10.4 / P04817 Arginine permease from Saccharomyces cerevisiae (Baker's yeast) (see 6 papers)
CAN1 / RF|NP_010851.1 arginine permease from Saccharomyces cerevisiae
37% identity, 95% coverage of query (322 bits)
TC 2.A.3.10.28 / O60170 Probable amino-acid permease Meu22 (Meiotic expression up-regulated protein 22) from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (see 2 papers)
34% identity, 98% coverage of query (321 bits)
agtA amino acid transporter from Emericella nidulans (see 2 papers)
36% identity, 96% coverage of query (312 bits)
CAN1_CANGA / Q6FNY1 Arginine permease CAN1 from Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus) (see paper)
35% identity, 98% coverage of query (311 bits)
DIP5_YEAST / P53388 Dicarboxylic amino acid permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
TC 2.A.3.10.13 / P53388 Dicarboxylic amino acid permease from Saccharomyces cerevisiae (Baker's yeast) (see 7 papers)
DIP5 / RF|NP_015058.1 dicarboxylic amino acid permease from Saccharomyces cerevisiae
35% identity, 97% coverage of query (309 bits)
LYP1_YEAST / P32487 Lysine-specific permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
TC 2.A.3.10.10 / P32487 Lysine permease of 611 aas and 13 putative TMSs, Lyp1 from Saccharomyces cerevisiae (Baker's yeast) (see 9 papers)
LYP1 / GI|1302328 lysine-specific permease from Saccharomyces cerevisiae
34% identity, 100% coverage of query (305 bits)
YQD2_SCHPO / Q9C0V0 Probable amino-acid permease PB1C11.02 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
35% identity, 98% coverage of query (300 bits)
GAP3_CANAL / A0A1D8PN88 Amino-acid permease GAP3 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 5 papers)
34% identity, 93% coverage of query (298 bits)
GAP1_CANAL / Q5AG77 Amino-acid permease GAP1 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 9 papers)
TC 2.A.3.10.23 / Q5AG77 Amino acid permease, GAP1. Transports Arg, Met, Leu and Phe from Candida albicans (see 2 papers)
GAP1 general amino acid permease from Candida albicans (see 3 papers)
36% identity, 97% coverage of query (297 bits)
RR42_RS28305 L-threonine:H+ symporter from Cupriavidus basilensis FW507-4G11
38% identity, 96% coverage of query (296 bits)
YI26_SCHPO / Q9P768 Uncharacterized amino-acid permease P7G5.06 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
per1 plasma membrane amino acid permease Per1 from Schizosaccharomyces pombe (see 2 papers)
34% identity, 99% coverage of query (295 bits)
GAP1_YEAST / P19145 General amino-acid permease GAP1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 19 papers)
TC 2.A.3.10.2 / P19145 General amino acid permease (all L-amino acids and some D-amino acids as well as β-alanine, polyamines and GABA) from Saccharomyces cerevisiae (Baker's yeast) (see 8 papers)
GAP1 / RF|NP_012965.1 general amino-acid permease GAP1 from Saccharomyces cerevisiae
37% identity, 95% coverage of query (292 bits)
PUT4_SCHPO / Q9URZ3 Probable proline-specific permease put4 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
36% identity, 93% coverage of query (292 bits)
CH_124074 putative amino-acid permease inda1 (T. harzianum) from Magnaporthe grisea 70-15 (see paper)
35% identity, 92% coverage of query (291 bits)
TC 2.A.3.10.17 / Q8J266 General amino acid uptake permease, GAP1 from Hebeloma cylindrosporum (see paper)
35% identity, 96% coverage of query (290 bits)
TC 2.A.3.10.21 / Q9URZ4 The basic amino acid (canavanine sensitivity) transporter, Cat1 from Schizosaccharomyces pombe (Fission yeast) (see 2 papers)
cat1 / RF|NP_595008.2 uncharacterized amino-acid permease C869.11 from Schizosaccharomyces pombe (see 3 papers)
35% identity, 95% coverage of query (288 bits)
CAT1_SCHPO / Q9URZ4 Cationic amino acid transporter 1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
35% identity, 95% coverage of query (288 bits)
GAP5_CANAL / A0A1D8PMB1 Amino-acid permease GAP5 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 2 papers)
35% identity, 99% coverage of query (288 bits)
ALP1_YEAST / P38971 Basic amino-acid permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
TC 2.A.3.10.11 / P38971 Basic amino acid permease from Saccharomyces cerevisiae (Baker's yeast) (see 5 papers)
ALP1 / RF|NP_014129.1 basic amino-acid permease from Saccharomyces cerevisiae
36% identity, 96% coverage of query (286 bits)
CAN1_CANAL / A0A1D8PPI5 Lysine/arginine permease CAN1; Basic amino acids permease CAN1 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 7 papers)
35% identity, 92% coverage of query (285 bits)
AAT1_SCHPO / Q9P5N2 Amino acid transporter 1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
33% identity, 96% coverage of query (285 bits)
TC 2.A.3.10.20 / P43059 The high affinity basic amino acid (Arg, Lys, His) transporter, Can1 from Candida albicans (Yeast) (see paper)
35% identity, 92% coverage of query (284 bits)
YifK / b3795 putative transporter YifK from Escherichia coli K-12 substr. MG1655 (see 5 papers)
thrP / P27837 threonine/serine:H+ symporter ThrP from Escherichia coli (strain K12) (see 5 papers)
39% identity, 88% coverage of query (280 bits)
CAN2_CANAL / Q59WU0 Probable lysine/arginine permease CAN2; Basic amino acids permease CAN2 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 7 papers)
35% identity, 95% coverage of query (275 bits)
PUT4_YEAST / P15380 Proline-specific permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
TC 2.A.3.10.3 / P15380 Proline permease from Saccharomyces cerevisiae (Baker's yeast) (see 4 papers)
PUT4 / RF|NP_014993.1 proline-specific permease from Saccharomyces cerevisiae
33% identity, 95% coverage of query (275 bits)
PS417_05405 L-alanine and D-alanine permease from Pseudomonas simiae WCS417
37% identity, 94% coverage of query (273 bits)
CAN3_CANAL / A0A1D8PPG4 Probable lysine/arginine permease CAN3; Basic amino acids permease CAN3 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 2 papers)
37% identity, 88% coverage of query (272 bits)
AO356_17670 L-alanine and D-alanine permease from Pseudomonas fluorescens FW300-N2C3
36% identity, 94% coverage of query (272 bits)
PheP / b0576 phenylalanine:H+ symporter PheP from Escherichia coli K-12 substr. MG1655 (see 3 papers)
pheP / P24207 phenylalanine:H+ symporter PheP from Escherichia coli (strain K12) (see 3 papers)
PHEP_ECOLI / P24207 Phenylalanine-specific permease; Phenylalanine:H(+) symporter PheP from Escherichia coli (strain K12) (see 6 papers)
TC 2.A.3.1.1 / P24207 Phenylalanine:H+ symporter, PheP of 458 aas and 12 established TMSs from Escherichia coli (see 6 papers)
38% identity, 85% coverage of query (271 bits)
AO353_16120 D-alanine and L-alanine transporter from Pseudomonas fluorescens FW300-N2E3
37% identity, 94% coverage of query (266 bits)
YHE1_SCHPO / Q9HDV2 Uncharacterized amino-acid permease PB2B2.01 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
32% identity, 99% coverage of query (265 bits)
HIP1_YEAST / P06775 Histidine permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
TC 2.A.3.10.1 / P06775 High affinity histidine permease (also implicated in Mn2+ efflux; Co2+, Ni2+, Zn2+ and Cu2+ uptake) from Saccharomyces cerevisiae (Baker's yeast) (see 5 papers)
HIP1 / GI|1323339 histidine permease from Saccharomyces cerevisiae
30% identity, 100% coverage of query (264 bits)
AAS52655.3 AEL030Wp from Eremothecium gossypii ATCC 10895 (see paper)
33% identity, 88% coverage of query (263 bits)
prnB / GB|CAA56191.1 proline-specific permease (proline transport protein) from Emericella nidulans (see 5 papers)
35% identity, 95% coverage of query (262 bits)
TAT2_YEAST / P38967 Tryptophan permease; Tryptophan amino acid transporter from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
TC 2.A.3.10.8 / P38967 Tryptophan permease, Tat2. Regulated via endocytosis by ATP-binding Cassette Transporters, Pdr5 (3.A.1.205.1) and Yor1 (3.A.208.3) as well as a seven-transmembrane protein, RSB1 (9.A.27.1.2) from Saccharomyces cerevisiae (Baker's yeast) (see 7 papers)
TAT2 / RF|NP_014622.1 tryptophan permease from Saccharomyces cerevisiae
35% identity, 88% coverage of query (261 bits)
TC 2.A.3.10.22 / Q2VQZ4 Arbuscular mycorrhizal fungal proline:H+ symporter, AAP1 (binds and probably transports nonpolar, hydrophobic amino acids) from Glomus mosseae (see paper)
34% identity, 99% coverage of query (258 bits)
isp5 / RF|NP_595000.1 amino acid permease Isp5 from Schizosaccharomyces pombe (see 2 papers)
34% identity, 97% coverage of query (256 bits)
AroR / b0112 aromatic amino acid:H+ symporter AroP from Escherichia coli K-12 substr. MG1655 (see 5 papers)
aroP / P15993 aromatic amino acid:H+ symporter AroP from Escherichia coli (strain K12) (see 6 papers)
AROP_ECOLI / P15993 Aromatic amino acid transport protein AroP; Aromatic amino acid:H(+) symporter AroP; General aromatic amino acid permease; General aromatic transport system from Escherichia coli (strain K12) (see 8 papers)
TC 2.A.3.1.3 / P15993 Aromatic amino acid:H+ symporter, AroP of 457 aas and 12 TMSs (Cosgriff and Pittard 1997). Transports phenylalanine, tyrosine and tryptophan from Escherichia coli (see 6 papers)
36% identity, 80% coverage of query (255 bits)
GAP4_CANAL / Q59WB3 S-adenosylmethionine permease GAP4; SAM permease; Amino-acid permease GAP4 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 6 papers)
TC 2.A.3.10.25 / Q59WB3 Arginine transporter, GAP4 from Candida albicans (see paper)
GAP4 potential general amino acid permease from Candida albicans (see paper)
34% identity, 93% coverage of query (253 bits)
YBXG_BACSU / P54425 Probable threonine/serine transporter YbxG from Bacillus subtilis (strain 168) (see paper)
35% identity, 86% coverage of query (250 bits)
TC 2.A.3.10.26 / Q59NZ6 General amino acid porter, GAP6. Transports almost all amino acids tested except arginine and citruline from Candida albicans (see paper)
34% identity, 85% coverage of query (248 bits)
GAP6_CANAL / A0A1D8PNP3 Amino-acid permease GAP6 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 5 papers)
34% identity, 85% coverage of query (248 bits)
AO353_05930 L-tryptophan transporter from Pseudomonas fluorescens FW300-N2E3
33% identity, 95% coverage of query (246 bits)
AGP1_YEAST / P25376 General amino acid permease AGP1; Asparagine/glutamine permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
TC 2.A.3.10.7 / P25376 Asn/Gln permease from Saccharomyces cerevisiae (Baker's yeast) (see 13 papers)
AGP1 / RF|NP_009905.3 general amino acid permease AGP1 from Saccharomyces cerevisiae
30% identity, 94% coverage of query (246 bits)
PfGW456L13_4291 L-tryptophan transporter from Pseudomonas fluorescens GW456-L13
34% identity, 93% coverage of query (244 bits)
AROP_CORGL / Q46065 Aromatic amino acid transport protein AroP; General aromatic amino acid permease from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
TC 2.A.3.1.12 / Q46065 Aromatic amino acid permease, AroP from Corynebacterium glutamicum (Brevibacterium flavum) (see 2 papers)
37% identity, 82% coverage of query (242 bits)
ANSP2_MYCTU / P9WQM7 L-asparagine permease 2; L-asparagine transport protein 2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
35% identity, 95% coverage of query (242 bits)
RR42_RS33495 L-phenylalanine:H+ symporter AroP from Cupriavidus basilensis FW507-4G11
35% identity, 86% coverage of query (242 bits)
H281DRAFT_04042 phenylacetate transporter from Paraburkholderia bryophila 376MFSha3.1
35% identity, 87% coverage of query (241 bits)
DagA / b4208 D-serine/alanine/glycine/:H+symporter from Escherichia coli K-12 substr. MG1655 (see 13 papers)
cycA / P0AAE0 D-serine/alanine/glycine:H+symporter from Escherichia coli (strain K12) (see 15 papers)
CYCA_ECOLI / P0AAE0 D-serine/D-alanine/glycine transporter; Amino acid carrier CycA from Escherichia coli (strain K12) (see 7 papers)
TC 2.A.3.1.7 / P0AAE0 D-Serine/D-alanine/glycine/D-cycloserine:H+ symporter from Escherichia coli (see 4 papers)
35% identity, 84% coverage of query (240 bits)
GabP / b2663 4-aminobutanoate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 11 papers)
gabP / P25527 4-aminobutanoate:H+ symporter from Escherichia coli (strain K12) (see 10 papers)
GABP_ECOLI / P25527 Gamma-aminobutyric acid permease; GABA permease; 4-aminobutyrate carrier; 4-aminobutyrate permease; Gamma-aminobutyrate permease from Escherichia coli (strain K12) (see 7 papers)
TC 2.A.3.1.4 / P25527 γ-aminobutyrate:H+ symporter, GabP. It also transports a variety of pyridine carboxylates. Phosphatidylethanolamine is required for its proper topological organization(Zhang et al. 2005) from Escherichia coli (see 5 papers)
34% identity, 80% coverage of query (238 bits)
TC 2.A.3.1.6 / P37460 Proline-specific permease (ProY) from Salmonella typhimurium (see 2 papers)
37% identity, 82% coverage of query (236 bits)
AO356_18530 L-tyrosine transporter from Pseudomonas fluorescens FW300-N2C3
34% identity, 80% coverage of query (234 bits)
AO353_12275 histidine permease from Pseudomonas fluorescens FW300-N2E3
36% identity, 86% coverage of query (234 bits)
Build an alignment for 16265 and 62 homologs with ≥ 30% identity
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GNP1_YEAST / P48813 High-affinity glutamine permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 5 papers)
TC 2.A.3.10.5 / P48813 High affinity glutamine permease from Saccharomyces cerevisiae (Baker's yeast) (see 12 papers)
GNP1 / GI|927778 high-affinity glutamine permease from Saccharomyces cerevisiae
28% identity, 96% coverage of query (227 bits)
SSY1_YEAST / Q03770 SPS-sensor component SSY1; Amino-acid permease homolog SSY1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 9 papers)
TC 2.A.3.10.12 / Q03770 Leucine sensor/transcription factor. Mutants hyper- and hyposensitive to inducer (Poulsen et al., 2008) suggest a sensor mechanism involving outward and inward facing conformations from Saccharomyces cerevisiae (Baker's yeast) (see 12 papers)
SSY1 / RF|NP_010444.1 amino-acid permease SSY1 from Saccharomyces cerevisiae (see paper)
26% identity, 100% coverage of query (177 bits)
YcjJ / b1296 putrescine:H+ symporter PuuP from Escherichia coli K-12 substr. MG1655 (see 4 papers)
puuP / P76037 putrescine:H+ symporter PuuP from Escherichia coli (strain K12) (see 2 papers)
PUUP_ECOLI / P76037 Putrescine importer PuuP from Escherichia coli (strain K12) (see 4 papers)
TC 2.A.3.1.13 / P76037 Putrescine importer, PuuP from Escherichia coli (strain K12) (see 4 papers)
24% identity, 79% coverage of query (87.8 bits)
6f34A / Q5L1G5 Crystal structure of a bacterial cationic amino acid transporter (cat) homologue bound to arginine. (see paper)
28% identity, 85% coverage of query (83.2 bits)
5oqtA Crystal structure of a bacterial cationic amino acid transporter (cat) homologue
28% identity, 85% coverage of query (82.8 bits)
6f2wA / A8UCQ5 Bacterial asc transporter crystal structure in open to in conformation (see paper)
22% identity, 91% coverage of query (59.3 bits)
CTR1_HUMAN / P30825 High affinity cationic amino acid transporter 1; CAT-1; CAT1; Ecotropic retroviral leukemia receptor homolog; Ecotropic retrovirus receptor homolog; Solute carrier family 7 member 1; System Y+ basic amino acid transporter from Homo sapiens (Human) (see 4 papers)
TC 2.A.3.3.9 / P30825 High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homologue) (Ecotropic retrovirus receptor homologue) (ERR) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) from Homo sapiens (see 6 papers)
20% identity, 72% coverage of query (57.0 bits)
LAT2_MOUSE / Q9QXW9 Large neutral amino acids transporter small subunit 2; L-type amino acid transporter 2; mLAT2; Solute carrier family 7 member 8 from Mus musculus (Mouse) (see 6 papers)
24% identity, 72% coverage of query (50.4 bits)
SLC7A8 / Q9UHI5 large neutral amino acids transporter small subunit 2 from Homo sapiens (see 4 papers)
LAT2_HUMAN / Q9UHI5 Large neutral amino acids transporter small subunit 2; L-type amino acid transporter 2; hLAT2; Solute carrier family 7 member 8 from Homo sapiens (Human) (see 14 papers)
TC 2.A.3.8.20 / Q9UHI5 Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (hLAT2) (Solute carrier family 7 member 8). Certain detergents stabilize and allow purification of the 4F2hc-LAT2 complex, allowing the measurement of substrate binding. In addition, an improved 3D map could be obtained from Homo sapiens (see 12 papers)
23% identity, 72% coverage of query (49.3 bits)
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Lawrence Berkeley National Laboratory