Searching for up to 100 curated homologs for 16352 FitnessBrowser__Keio:16352 (267 a.a.)

Found high-coverage hits (≥70%) to 28 curated proteins.

Removed hits that are identical to the query, leaving 26

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

7et9A / A0A8I1ZEE8 Crystal structure of abhpai-zn-pyruvate complex, class ii aldolase, hpai from acinetobacter baumannii (see paper)
    61% identity, 94% coverage of query (309 bits)

7etiA Crystal structure of abhpai-zn-pyruvate-4-hydroxybenzaldehyde complex, class ii aldolase, hpai from acinetobacter baumannii
    61% identity, 93% coverage of query (308 bits)

7etfA Crystal structure of abhpai-mn-pyruvate-succinic semialdehyde complex, class ii aldolase, hpai from acinetobacter baumannii
    61% identity, 93% coverage of query (308 bits)

7eteA Crystal structure of abhpai-mg-(4r)-kdgal complex, class ii aldolase, hpai from acinetobacter baumannii
    61% identity, 93% coverage of query (308 bits)

7etdA Crystal structure of abhpai-zn-(4s)-kdglu complex, class ii aldolase, hpai from acinetobacter baumannii
    61% identity, 93% coverage of query (308 bits)

7etcA Crystal structure of abhpai-zn-(4r)-kdgal complex, class ii aldolase, hpai from acinetobacter baumannii
    61% identity, 93% coverage of query (308 bits)

7etbA Crystal structure of abhpai-mn-pyruvate complex, class ii aldolase, hpai from acinetobacter baumannii
    61% identity, 93% coverage of query (308 bits)

7etaA Crystal structure of abhpai-co-pyruvate complex, class ii aldolase, hpai from acinetobacter baumannii
    61% identity, 93% coverage of query (308 bits)

7ethA Crystal structure of abhpai-zn-pyruvate-propionaldehyde complex, class ii aldolase, hpai from acinetobacter baumannii
    61% identity, 93% coverage of query (308 bits)

2v5kA / Q47098 Class ii aldolase hpch - magnesium - oxamate complex (see paper)
    58% identity, 88% coverage of query (285 bits)

HPCH_ECOLX / Q47098 4-hydroxy-2-oxo-heptane-1,7-dioate aldolase; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; HHED aldolase; 4-hydroxy-2-ketoheptane-1,7-dioate aldolase; HKHD aldolase; EC 4.1.2.52 from Escherichia coli (see 3 papers)
B1IS70 4-hydroxy-2-oxoheptanedioate aldolase (EC 4.1.2.52) from Escherichia coli (see paper)
Q47098 4-hydroxy-2-oxoheptanedioate aldolase (EC 4.1.2.52); 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.39) from Escherichia coli (see 3 papers)
    58% identity, 88% coverage of query (285 bits)

4b5vA Crystal structures of divalent metal dependent pyruvate aldolase, hpai, in complex with 4-hydroxyl-2-ketoheptane-1,7-dioate
    58% identity, 88% coverage of query (285 bits)

4b5tA Crystal structures of divalent metal dependent pyruvate aldolase, hpai, in complex with ketobutyrate
    58% identity, 88% coverage of query (285 bits)

4b5sA Crystal structures of divalent metal dependent pyruvate aldolase, hpai, in complex with pyruvate
    58% identity, 88% coverage of query (285 bits)

BPHF_RHOJR / O05151 4-hydroxy-2-oxovalerate aldolase; HOA; EC 4.1.3.39 from Rhodococcus jostii (strain RHA1) (see paper)
    52% identity, 92% coverage of query (250 bits)

YhaF / b3126 α-dehydro-β-deoxy-D-glucarate aldolase (EC 4.1.2.20) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
garL / P23522 α-dehydro-β-deoxy-D-glucarate aldolase (EC 4.1.2.20) from Escherichia coli (strain K12) (see 2 papers)
GARL_ECOLI / P23522 5-keto-4-deoxy-D-glucarate aldolase; KDGluc aldolase; KDGlucA; 2-dehydro-3-deoxy-D-glucarate aldolase; 2-keto-3-deoxy-D-glucarate aldolase; 5-dehydro-4-deoxy-D-glucarate aldolase; Alpha-keto-beta-deoxy-D-glucarate aldolase; EC 4.1.2.20 from Escherichia coli (strain K12) (see 3 papers)
    44% identity, 95% coverage of query (217 bits)

1dxeA / P23522 2-dehydro-3-deoxy-galactarate aldolase from escherichia coli (see paper)
    44% identity, 94% coverage of query (215 bits)

1dxfA 2-dehydro-3-deoxy-galactarate aldolase from escherichia coli in complex with pyruvate
    44% identity, 94% coverage of query (215 bits)

KDSGA_PSEPU / P0DOV8 2-dehydro-3,6-dideoxy-6-sulfogluconate aldolase; 2-keto-3,6-dideoxy-6-sulfogluconate aldolase; KDSG aldolase; EC 4.1.2.58 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
P0DOV8 2-dehydro-3,6-dideoxy-6-sulfogluconate aldolase (EC 4.1.2.58) from Pseudomonas putida (see paper)
    39% identity, 94% coverage of query (194 bits)

7nr1A Crystal structure of holo-s116a mutant of hydroxy ketone aldolase (swhka) from sphingomonas wittichii rw1 (see paper)
    33% identity, 92% coverage of query (115 bits)

8adqA / A0A9J9HGY6 Crystal structure of holo-swhpa-mg (hydroxy ketone aldolase) from sphingomonas wittichii rw1 in complex with hydroxypyruvate and d- glyceraldehyde (see paper)
    33% identity, 92% coverage of query (115 bits)

7o5rA Crystal structure of holo-swhpa-mn (hydroxyketoacid aldolase) from sphingomonas wittichii rw1
    33% identity, 92% coverage of query (115 bits)

A0A0H3K9Z0 citrate synthase (unknown stereospecificity) (EC 2.3.3.16) from Staphylococcus aureus (see paper)
    32% identity, 89% coverage of query (104 bits)

4tv5A / A0A0H3K9Z0 Crystal structure of citrate synthase sbng (see paper)
    30% identity, 89% coverage of query (94.0 bits)

4tv6A Crystal structure of citrate synthase variant sbng e151q
    30% identity, 89% coverage of query (85.9 bits)

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Build an alignment for 16352 and 25 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

TASA_HAPIR / A0A0F7GG11 4-hydroxy-4-methyl-2-oxoglutarate aldolase tasA; Tetramic acid Sch210971/2 biosynthesis cluster protein A; EC 4.1.3.17 from Hapsidospora irregularis (see paper)
    27% identity, 80% coverage of query (76.6 bits)

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