Sites on a Tree

 

Searching for up to 100 curated homologs for 16800 b2716 cryptic 6-phospho-beta-glucosidase (NCBI) (474 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

Removed hits that are identical to the query, leaving 98

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

BAB36995.1 6-P-β-glucosidase (AscB;ECs3572) (EC 3.2.1.86) (see protein)
    98% identity, 100% coverage of query (974 bits)

AAT45375.1 6-P-β-glucosidase (AscB) (EC 3.2.1.21|3.2.1.86) (see protein)
    83% identity, 100% coverage of query (845 bits)

L7Y2Z6 6-phospho-beta-glucosidase (EC 3.2.1.86) from uncultured organism (see paper)
AGD88872.1 6-phospho-β-glucosidase (Pbgl25-217) (EC 3.2.1.86) (see protein)
    63% identity, 99% coverage of query (651 bits)

AAN58797.1 6-P-β-glucosidase (Arb;AscB;SMU.1102) (EC 3.2.1.86) (see protein)
    63% identity, 100% coverage of query (635 bits)

AFS64714.1 β-glucosidase (BglZ) (EC 3.2.1.21) (see protein)
    58% identity, 100% coverage of query (589 bits)

BGLH_BACSU / P40740 Aryl-phospho-beta-D-glucosidase BglH; 6-phospho-beta-glucosidase; EC 3.2.1.86 from Bacillus subtilis (strain 168) (see paper)
CAB15962.2 6-P-β-glucosidase 1 (BglH;N17D;BSU39260) (EC 3.2.1.86) (see protein)
    57% identity, 99% coverage of query (582 bits)

bglH / CAA84287.1 beta-glucosidase from Bacillus subtilis (see paper)
    57% identity, 99% coverage of query (580 bits)

AAB51564.1 6-P-β-glucosidase / phospho-cellobiase (CasB) (EC 3.2.1.86) (see protein)
    55% identity, 100% coverage of query (547 bits)

AAC05714.1 6-P-β-glucosidase (AbgA) (EC 3.2.1.86) (see protein)
abgA / AAC05714.1 phospho-beta-glucosidase from Clostridium longisporum (see paper)
    54% identity, 99% coverage of query (543 bits)

BlgA / b3721 6-phospho-β-glucosidase B (EC 3.2.1.86) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
bglB / P11988 6-phospho-β-glucosidase B (EC 3.2.1.86) from Escherichia coli (strain K12) (see 2 papers)
BGLB_ECOLI / P11988 6-phospho-beta-glucosidase BglB; Phospho-beta-glucosidase B; EC 3.2.1.86 from Escherichia coli (strain K12) (see paper)
AAC76744.1 6-P-β-glucosidase (BglB;b3721) (EC 3.2.1.86) (see protein)
    54% identity, 100% coverage of query (541 bits)

Q6QGY5 beta-glucosidase (EC 3.2.1.21) from Pectobacterium carotovorum (see paper)
    54% identity, 99% coverage of query (536 bits)

bglA / AAO15902.1 beta-glucosidase protein from Corynebacterium glutamicum (see paper)
    54% identity, 100% coverage of query (534 bits)

AAM82757.1 6-P-β-glucosidase (BglB) (EC 3.2.1.86) (see protein)
    55% identity, 100% coverage of query (531 bits)

AAA24815.1 6-P-β-glucosidase (ArbB) (EC 3.2.1.86) (see protein)
    55% identity, 99% coverage of query (527 bits)

ADT62000.1 β-glucosidase / β-xylosidase (BglB;P11-6B) (EC 3.2.1.21|3.2.1.37) (see protein)
    53% identity, 100% coverage of query (526 bits)

AAN58686.1 6-P-β-glucosidase (BglA;SMU.985) (EC 3.2.1.86) (see protein)
    53% identity, 99% coverage of query (523 bits)

AAX57580.1 β-glucosidase (CasB) (EC 3.2.1.21) (see protein)
    54% identity, 100% coverage of query (517 bits)

A0A0H2UP35 6-phospho-beta-glucosidase (EC 3.2.1.86) from Streptococcus pneumoniae (see paper)
AAK74732.1 6-P-β-glucosidase (BglA-2;SP0578) (EC 3.2.1.86) (see protein)
    51% identity, 100% coverage of query (513 bits)

BGLA_BACSU / P42973 Aryl-phospho-beta-D-glucosidase BglA; 6-phospho-beta-glucosidase; EC 3.2.1.86 from Bacillus subtilis (strain 168) (see 2 papers)
AAA22660.1 6-P-β-glucosidase (BglA;BSU40110) (EC 3.2.1.86) (see protein)
    51% identity, 100% coverage of query (509 bits)

CAA75906.1 aryl 6-P-β-glucosidase (BglH;BglT) (EC 3.2.1.86) (see protein)
    51% identity, 99% coverage of query (508 bits)

YqfC / b2901 6-phospho-β-glucosidase A (EC 3.2.1.86) from Escherichia coli K-12 substr. MG1655 (see 10 papers)
bglA / Q46829 6-phospho-β-glucosidase A (EC 3.2.1.86) from Escherichia coli (strain K12) (see 9 papers)
BGLA_ECOLI / Q46829 6-phospho-beta-glucosidase BglA; Phospho-beta-glucosidase A; EC 3.2.1.86 from Escherichia coli (strain K12) (see paper)
Q46829 6-phospho-beta-glucosidase (EC 3.2.1.86) from Escherichia coli (see paper)
AAC75939.1 6-P-β-glucosidase A (BglA;b2901) (EC 3.2.1.86) (see protein)
    51% identity, 99% coverage of query (503 bits)

4ipnE / A0A0H2UP35 The complex structure of 6-phospho-beta-glucosidase bgla-2 with thiocellobiose-6p from streptococcus pneumoniae (see paper)
    51% identity, 100% coverage of query (500 bits)

BAB37196.1 6-P-β-glucosidase (BglA;ECs3773) (EC 3.2.1.86) (see protein)
    51% identity, 99% coverage of query (500 bits)

AAN59243.1 6-P-β-glucosidase (CelA;Bgl;SmBgl;SMU.1601;SMU_1601) (EC 3.2.1.86) (see protein)
    49% identity, 100% coverage of query (499 bits)

4f66A / Q8DT00 The crystal structure of 6-phospho-beta-glucosidase from streptococcus mutans ua159 in complex with beta-d-glucose-6-phosphate. (see paper)
    49% identity, 100% coverage of query (499 bits)

BAB94107.1 6-P-β-glucosidase (BglA;MW0242) (EC 3.2.1.86) (see protein)
    49% identity, 100% coverage of query (498 bits)

4f79A The crystal structure of 6-phospho-beta-glucosidase mutant (e375q) in complex with salicin 6-phosphate
    49% identity, 100% coverage of query (498 bits)

4ipnB The complex structure of 6-phospho-beta-glucosidase bgla-2 with thiocellobiose-6p from streptococcus pneumoniae
    50% identity, 100% coverage of query (498 bits)

4gpnB The crystal structure of 6-p-beta-d-glucosidase (e375q mutant) from streptococcus mutans ua150 in complex with gentiobiose 6-phosphate.
    49% identity, 100% coverage of query (496 bits)

AAZ88293.1 6-P-β-glucosidase (BglB;SSO_1595) (EC 3.2.1.86) (see protein)
    49% identity, 100% coverage of query (486 bits)

BAB56428.1 6-P-β-glucosidase (SAV0266;BglA) (EC 3.2.1.86) (see protein)
    49% identity, 100% coverage of query (486 bits)

AAV37466.1 6-P-β-glucosidase (BglA) (EC 3.2.1.21|3.2.1.86) (see protein)
    49% identity, 100% coverage of query (484 bits)

BAA25004.1 6-P-β-galactosidase II (Pbg2) (EC 3.2.1.86) (see protein)
    50% identity, 99% coverage of query (482 bits)

ABJ60960.1 6-P-β-glucosidase (Pbg2;LGAS_1668) (EC 3.2.1.86) (see protein)
    50% identity, 99% coverage of query (482 bits)

ABJ56211.1 6-P-β-glucosidase (BglD;OEOE_0224) (EC 3.2.1.86) (see protein)
    48% identity, 99% coverage of query (469 bits)

ABJ59596.1 6-P-β-glucosidase (Pbg1;LGAS_0185) (EC 3.2.1.86) (see protein)
    49% identity, 100% coverage of query (466 bits)

O06532 6-phospho-beta-galactosidase (EC 3.2.1.85); 6-phospho-beta-glucosidase (EC 3.2.1.86) from Lactobacillus gasseri (see paper)
BAA20086.1 6-P-β-galactosidase 1 (Pbg1) (EC 3.2.1.86) (see protein)
    49% identity, 100% coverage of query (465 bits)

ABJ56315.1 6P-β-glucosidase (CelD;OEOE_0341) (EC 3.2.1.86) (see protein)
    48% identity, 99% coverage of query (465 bits)

3qomA / F9UU25 Crystal structure of 6-phospho-beta-glucosidase from lactobacillus plantarum (see paper)
    49% identity, 99% coverage of query (464 bits)

BAD76622.1 β-galactosidase (GKGal1A;GK2337) (Gal1A) (EC 3.2.1.23) (see protein)
    45% identity, 100% coverage of query (416 bits)

AAD28227.1 6-P-β-glucosidase (BglB) (EC 3.2.1.86) (see protein)
    43% identity, 99% coverage of query (410 bits)

ADD01617.1 Thit_0299 (EC 3.2.1.-) (see protein)
    42% identity, 100% coverage of query (364 bits)

BAD77499.1 6-phospho-β-glycosidase (GK3214) (EC 3.2.1.85|3.2.1.86) (see protein)
    39% identity, 100% coverage of query (342 bits)

AAX76617.1 β-glucosidase (BglY) (EC 3.2.1.21) (see protein)
    41% identity, 100% coverage of query (340 bits)

8b80A / W8QF82 The structure of gan1d w433a in complex with galactose-6p
    38% identity, 100% coverage of query (339 bits)

4zfmC Structure of gan1d-e170q in complex with cellobiose-6-phosphate
    39% identity, 100% coverage of query (339 bits)

W8QF82 6-phospho-beta-galactosidase (EC 3.2.1.85); 6-phospho-beta-glucosidase (EC 3.2.1.86) from Geobacillus stearothermophilus (see 2 papers)
AHL67640.1 6-P-β-galactosidase (Gan1D) (EC 3.2.1.86) (see protein)
    38% identity, 100% coverage of query (337 bits)

5okbB High resolution structure of native gan1d, a putative 6-phospho-beta- galactosidase from geobacillus stearothermophilus
    38% identity, 100% coverage of query (337 bits)

4zepA Structure of gan1d, a 6-phospho-beta-galactosidase from geobacillus stearothermophilus, in complex with 6-phospho-glucose
    38% identity, 100% coverage of query (337 bits)

BGLC_BACSU / P42403 Aryl-phospho-beta-D-glucosidase BglC; 6-phospho-beta-glucosidase; EC 3.2.1.86 from Bacillus subtilis (strain 168) (see paper)
CAB12135.1 6-P-β-glucosidase (YckE;BglC;BSU03410) (EC 3.2.1.86) (see protein)
    39% identity, 99% coverage of query (322 bits)

AHC94275.1 aryl-P-β-glucosidase (BglC) (EC 3.2.1.-) (see protein)
    38% identity, 99% coverage of query (315 bits)

AAB49339.1 6-P-β-glucosidase (PbgA) (EC 3.2.1.86) (see protein)
    39% identity, 99% coverage of query (304 bits)

5yifA Pyruvylated beta-d-galactosidase from bacillus sp. Hma207, e163a mutant pyruvylated beta-d-galactose complex (see paper)
    36% identity, 99% coverage of query (265 bits)

6z1mA Structure of an ancestral glycosidase (family 1) bound to heme (see paper)
    35% identity, 99% coverage of query (262 bits)

6qwiA / P22073 Structure of beta-glucosidase a from paenibacillus polymyxa complexed with multivalent inhibitors. (see paper)
    33% identity, 98% coverage of query (243 bits)

B8CYA8 beta-glucosidase (EC 3.2.1.21) from Halothermothrix orenii (see paper)
ACL70277.1 β-glucosidase A (BglA;HoBGLA;Hore_15280) (EC 3.2.1.21) (see protein)
    33% identity, 98% coverage of query (243 bits)

4ptvA / B8CYA8 Halothermothrix orenii beta-glucosidase a, thiocellobiose complex (see paper)
    33% identity, 98% coverage of query (243 bits)

6r4kA Structure of beta-glucosidase a from paenibacillus polymyxa complexed with a monovalent inhibitor
    33% identity, 98% coverage of query (243 bits)

4ptwA Halothermothrix orenii beta-glucosidase a, 2-deoxy-2-fluoro-glucose complex
    33% identity, 98% coverage of query (243 bits)

P26208 beta-glucosidase (EC 3.2.1.21) from Acetivibrio thermocellus (see paper)
CAA42814.1 exo-β-glucosidase 1A (BglA; β-G;Cthe_0212) (Glc1A) (EC 3.2.1.21) (see protein)
    32% identity, 99% coverage of query (242 bits)

8ivyA / P26208 Beta-glucosidase bgla mutant e166q in complex with glucose (see paper)
    32% identity, 99% coverage of query (240 bits)

6z1hA Ancestral glycosidase (family 1) (see paper)
    34% identity, 99% coverage of query (240 bits)

AAK78365.1 CAC0385 (EC 3.2.1.86) (see protein)
    34% identity, 99% coverage of query (240 bits)

AAA22263.1 β-glucosidase A (BglA) (EC 3.2.1.21) (see protein)
    33% identity, 98% coverage of query (239 bits)

1e4iA 2-deoxy-2-fluoro-beta-d-glucosyl/enzyme intermediate complex of the beta-glucosidase from bacillus polymyxa
    33% identity, 98% coverage of query (239 bits)

1bggB Glucosidase a from bacillus polymyxa complexed with gluconate
    33% identity, 98% coverage of query (239 bits)

ACK43071.1 β-galactosidase (Dtur_1799) (EC 3.2.1.-) (see protein)
    33% identity, 99% coverage of query (238 bits)

BGL42_ARATH / Q9FIW4 Beta-glucosidase 42; AtBGLU42; EC 3.2.1.21 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    33% identity, 99% coverage of query (237 bits)

BAD76141.1 6-phospho-β-glycosidase (GK1856) (EC 3.2.1.85|3.2.1.86) (see protein)
    36% identity, 99% coverage of query (234 bits)

ACI19973.1 β-glucosidase (DtGH;DICTH_1689) (EC 3.2.1.21) (see protein)
    33% identity, 99% coverage of query (233 bits)

ABJ59900.1 6-P-β-galactosidase (LacG2;LGAS_0502) (EC 3.2.1.85) (see protein)
    32% identity, 97% coverage of query (229 bits)

BAA36160.1 β-glucosidase A (EC 3.2.1.21) (see protein)
    32% identity, 99% coverage of query (229 bits)

LACG_LACLL / P11546 6-phospho-beta-galactosidase; Beta-D-phosphogalactoside galactohydrolase; PGALase; P-beta-Gal; PBG; EC 3.2.1.85 from Lactococcus lactis subsp. lactis (Streptococcus lactis) (see paper)
AAA25183.1 6-P-β-galactosidase (LacG) (EC 3.2.1.85) (see protein)
    35% identity, 98% coverage of query (229 bits)

Q2WGB4 beta-glucosidase (EC 3.2.1.21) from Paenibacillus sp. (see paper)
BAE48718.1 β-glucosidase (BglA) (EC 3.2.1.21) (see protein)
    34% identity, 98% coverage of query (228 bits)

LACG_LEPBD / C7N8L9 6-phospho-beta-galactosidase; Beta-D-phosphogalactoside galactohydrolase; PGALase; P-beta-Gal; PBG; EC 3.2.1.85 from Leptotrichia buccalis (strain ATCC 14201 / DSM 1135 / JCM 12969 / NCTC 10249 / C-1013-b) (see paper)
    34% identity, 97% coverage of query (226 bits)

4pbgA / P11546 6-phospho-beta-galactosidase form-cst (see paper)
    35% identity, 98% coverage of query (225 bits)

AAA16450.1 6-P-β-galactosidase (LacG) (EC 3.2.1.85) (see protein)
lacG / AAA16450.1 phospho-beta-galactosidase from Streptococcus mutans (see 2 papers)
    34% identity, 98% coverage of query (223 bits)

AAN59144.1 6-P-β-galactosidase (LacG;SMU.1490) (EC 3.2.1.85) (see protein)
    34% identity, 98% coverage of query (223 bits)

ABJ54846.1 6-P-β-glucosidase (BglA3;SPD_0247) (EC 3.2.1.86) (see protein)
    33% identity, 99% coverage of query (222 bits)

ABV10357.1 6-P-β-galactosidase (LacG;SGO_1512) (EC 3.2.1.85) (see protein)
    34% identity, 97% coverage of query (222 bits)

ABL14155.1 β-glucosidase (CelG) (EC 3.2.1.21) (see protein)
    35% identity, 99% coverage of query (222 bits)

lacG / P11175 phospho-β-galactosidase (EC 3.2.1.85) from Staphylococcus aureus (see paper)
AAA26650.1 6-P-β-galactosidase (SAV2189) (EC 3.2.1.85) (see protein)
    35% identity, 98% coverage of query (222 bits)

P11175 6-phospho-beta-galactosidase; Beta-D-phosphogalactoside galactohydrolase; PGALase; P-beta-Gal; PBG; EC 3.2.1.85 from Staphylococcus aureus
    35% identity, 98% coverage of query (222 bits)

BAB05642.1 β-glucosidase (BglA;BH1923) (EC 3.2.1.21) (see protein)
    32% identity, 98% coverage of query (221 bits)

AAA22266.1 β-glucosidase (BglA) (EC 3.2.1.21) (see protein)
bglA / AAA22266.1 beta-glucosidase from Bacillus circulans (see paper)
    33% identity, 100% coverage of query (219 bits)

AAQ00997.1 β-glucosidase A (BglA;BG) (EC 3.2.1.21) (see protein)
    33% identity, 98% coverage of query (218 bits)

GMUD_BACSU / O05508 6-phospho-beta-glucosidase GmuD; Aryl-phospho-beta-D-glucosidase BglD; Glucomannan utilization protein D; EC 3.2.1.86 from Bacillus subtilis (strain 168) (see 2 papers)
BAA19708.1 6-P-β-glucosidase (YdhP;BSU05840) (EC 3.2.1.86) (see protein)
    34% identity, 99% coverage of query (216 bits)

AAD15134.1 6-P-β-galactosidase (EC 3.2.1.85) (see protein)
    32% identity, 97% coverage of query (214 bits)

BGLA_THENN / B9K7M5 1,4-beta-D-glucan glucohydrolase; Glucan glucohydrolase; Beta-D-glucoside glucohydrolase; Beta-glucosidase; Glucan 1,4-beta-glucosidase; EC 3.2.1.74; EC 3.2.1.21 from Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NBRC 107923 / NS-E) (see paper)
B9K7M5 beta-glucosidase (EC 3.2.1.21) from Thermotoga neapolitana (see paper)
    32% identity, 99% coverage of query (213 bits)

AAN60220.1 β-glucosidase (BglA) (EC 3.2.1.21) (see protein)
    33% identity, 99% coverage of query (212 bits)

ACF00459.1 Rpal_1936 (EC 3.2.1.21) (see protein)
    32% identity, 98% coverage of query (210 bits)

4hz7A / Q0GMU3 Crystal structure of bglb with glucose (see paper)
    31% identity, 99% coverage of query (208 bits)

1w3jA Family 1 b-glucosidase from thermotoga maritima in complex with tetrahydrooxazine
    31% identity, 99% coverage of query (207 bits)

1oifA Family 1 b-glucosidase from thermotoga maritima
    31% identity, 99% coverage of query (207 bits)

2j78A Beta-glucosidase from thermotoga maritima in complex with gluco- hydroximolactam
    31% identity, 99% coverage of query (207 bits)

2jalB / Q08638 Beta-glucosidase from thermotoga maritima in complex with cyclophellitol (see paper)
    31% identity, 99% coverage of query (207 bits)

5ossB Beta-glucosidase from thermotoga maritima in complex with gluco-1h- imidazole
    31% identity, 99% coverage of query (207 bits)

5n6tA Thermotoga maritima family 1 glycoside hydrolase complexed with a cyclophellitol analogue transition state mimic
    31% identity, 99% coverage of query (207 bits)

Build an alignment

Build an alignment for 16800 and 98 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory