Searching for up to 100 curated homologs for 17442 FitnessBrowser__Keio:17442 (292 a.a.)
Found high-coverage hits (≥70%) to 72 curated proteins.
Removed hits that are identical to the query, leaving 69
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
C4KKZ9 arylesterase (EC 3.1.1.2); 1,4-lactonase (EC 3.1.1.25); aryldialkylphosphatase (EC 3.1.8.1) from Sulfolobus islandicus (see 2 papers)
4g2dA / C4KKZ9 Crystal structure of the hyperthermophilic sulfolobus islandicus pll sislac (see paper)
32% identity, 98% coverage of query (147 bits)
PHP_SACS2 / Q97VT7 Aryldialkylphosphatase; Paraoxonase; SsoPox; Phosphotriesterase-like lactonase; EC 3.1.8.1 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 2 papers)
Q97VT7 1,4-lactonase (EC 3.1.1.25); quorum-quenching N-acyl-homoserine lactonase (EC 3.1.1.81); aryldialkylphosphatase (EC 3.1.8.1) from Saccharolobus solfataricus (see 11 papers)
31% identity, 98% coverage of query (142 bits)
3uf9A Crystal structure of ssopox in complex with the phosphotriester fensulfothion
31% identity, 98% coverage of query (142 bits)
2vc7A Structural basis for natural lactonase and promiscuous phosphotriesterase activities
31% identity, 98% coverage of query (142 bits)
Q4J6Z8 arylesterase (EC 3.1.1.2); 1,4-lactonase (EC 3.1.1.25); aryldialkylphosphatase (EC 3.1.8.1) from Sulfolobus acidocaldarius (see 2 papers)
32% identity, 98% coverage of query (141 bits)
5w3uD / Q97VT7 Crystal structure of ssopox asb5 mutant (v27a-i76t-y97w-y99f-l130p- l226v) (see paper)
31% identity, 98% coverage of query (141 bits)
5w3zD / Q97VT7 Crystal structure of ssopox asc6 mutant (l72i-y99f-i122l-l228m-f229s- w263l) (see paper)
31% identity, 98% coverage of query (139 bits)
3k2gB / Q3IVY4 Crystal structure of a resiniferatoxin-binding protein from rhodobacter sphaeroides
31% identity, 92% coverage of query (132 bits)
4h9tA Structure of geobacillus kaustophilus lactonase, mutant e101n with bound n-butyryl-dl-homoserine lactone
31% identity, 98% coverage of query (132 bits)
5ch9A / Q5KZU5 Gkap mutant b12
31% identity, 98% coverage of query (130 bits)
3ojgA Structure of an inactive lactonase from geobacillus kaustophilus with bound n-butyryl-dl-homoserine lactone
31% identity, 98% coverage of query (130 bits)
6jstA Structure of geobacillus kaustophilus lactonase, y99p/d266n double mutant with bound 3-oxo-c8-hsl
31% identity, 98% coverage of query (130 bits)
Build an alignment for 17442 and 12 homologs with ≥ 30% identity
Or download the sequences
3pnzA Crystal structure of the lactonase lmo2620 from listeria monocytogenes
28% identity, 98% coverage of query (127 bits)
4if2A / P9WHN9 Structure of the phosphotriesterase from mycobacterium tuberculosis (see paper)
31% identity, 98% coverage of query (124 bits)
P9WHN9 aryldialkylphosphatase (EC 3.1.8.1) from Mycobacterium tuberculosis (see paper)
31% identity, 98% coverage of query (124 bits)
P9WHN9 Phosphotriesterase homology protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
31% identity, 98% coverage of query (124 bits)
7p85A Engineered phosphotriesterase bdpte 10-2-c3(c59v/c227v) in complex with ethyl-4-methylbenzylphosphonate
29% identity, 100% coverage of query (122 bits)
3gtxA / Q9RVU2 D71g/e101g mutant in organophosphorus hydrolase from deinococcus radiodurans (see paper)
29% identity, 98% coverage of query (121 bits)
3htwA Organophosphorus hydrolase from deinococcus radiodurans with cacodylate bound
29% identity, 98% coverage of query (121 bits)
3fdkA Crystal structure of hydrolase dr0930 with promiscuous catalytic activity
29% identity, 98% coverage of query (121 bits)
2o4qA Structure of phosphotriesterase mutant g60a
28% identity, 100% coverage of query (120 bits)
6bh7A / A0A060GYS7 Phosphotriesterase variant r18+254s
29% identity, 100% coverage of query (119 bits)
Q93LD7 aryldialkylphosphatase (EC 3.1.8.1) from Agrobacterium tumefaciens (see 5 papers)
28% identity, 98% coverage of query (119 bits)
1p6bB X-ray structure of phosphotriesterase, triple mutant h254g/h257w/l303t
28% identity, 100% coverage of query (119 bits)
1qw7A Structure of an engineered organophosphorous hydrolase with increased activity toward hydrolysis of phosphothiolate bonds
28% identity, 100% coverage of query (119 bits)
1i0dA High resolution structure of the zinc/cadmium-containing phosphotriesterase from pseudomonas diminuta
28% identity, 100% coverage of query (119 bits)
1i0bA High resolution structure of the manganese-containing phosphotriesterase from pseudomonas diminuta
28% identity, 100% coverage of query (119 bits)
3cakA X-ray structure of wt pte with ethyl phosphate
28% identity, 100% coverage of query (119 bits)
1eywA Three-dimensional structure of the zinc-containing phosphotriesterase with bound substrate analog triethylphosphate
28% identity, 100% coverage of query (119 bits)
opd / P0A433 organophosphate acid anhydrase (EC 3.1.8.1) from Sphingobium fuliginis (strain ATCC 27551) (see 5 papers)
opd / P0A434 parathion hydrolase (EC 3.1.8.1) from Brevundimonas diminuta (see 3 papers)
K4I2M6 aryldialkylphosphatase (EC 3.1.8.1) from Sphingobium fuliginis (see paper)
P0A433 aryldialkylphosphatase (EC 3.1.8.1); diisopropyl-fluorophosphatase (EC 3.1.8.2) from Sphingobium fuliginis (see 2 papers)
P0A434 arylesterase (EC 3.1.1.2); aryldialkylphosphatase (EC 3.1.8.1); diisopropyl-fluorophosphatase (EC 3.1.8.2) from Brevundimonas diminuta (see 11 papers)
28% identity, 100% coverage of query (118 bits)
Q5UB52 aryldialkylphosphatase (EC 3.1.8.1) from Flavobacterium sp. MTCC 2495 (see paper)
28% identity, 100% coverage of query (118 bits)
3rhgA / B4EXV8 Crystal structure of amidohydrolase pmi1525 (target efi-500319) from proteus mirabilis hi4320
28% identity, 98% coverage of query (118 bits)
P0A433 Parathion hydrolase; Phosphotriesterase; PTE; EC 3.1.8.1 from Sphingobium fuliginis (strain ATCC 27551)
28% identity, 100% coverage of query (118 bits)
P0A434 Parathion hydrolase; Phosphotriesterase; PTE; EC 3.1.8.1 from Brevundimonas diminuta (Pseudomonas diminuta)
28% identity, 100% coverage of query (118 bits)
1dpmA Three-dimensional structure of the zinc-containing phosphotriesterase with bound substrate analog diethyl 4- methylbenzylphosphonate
28% identity, 100% coverage of query (118 bits)
5vejA High resolution crystal structure of a fluoride-inhibited organo- phosphate-degrading metallohydrolase
28% identity, 98% coverage of query (118 bits)
1ez2A Three-dimensional structure of the zinc-containing phosphotriesterase with bound substrate analog diisopropylmethyl phosphonate.
28% identity, 100% coverage of query (118 bits)
2r1lA Opda from agrobacterium radiobacter with bound diethyl thiophosphate from crystal soaking with the compound- 1.95 a
28% identity, 98% coverage of query (118 bits)
2r1kA Opda from agrobacterium radiobacter with bound diethyl phosphate from crystal soaking with the compound- 1.9 a
28% identity, 98% coverage of query (118 bits)
3so7A Organophoshatedegrading enzyme (opda)-phosphate complex
28% identity, 98% coverage of query (118 bits)
2d2jA Opda from agrobacterium radiobacter without inhibitor/product present at 1.75 a resolution
28% identity, 98% coverage of query (118 bits)
2d2hA Opda from agrobacterium radiobacter with bound inhibitor trimethyl phosphate at 1.8 a resolution
28% identity, 98% coverage of query (118 bits)
2d2gA Opda from agrobacterium radiobacter with bound product dimethylthiophosphate
28% identity, 98% coverage of query (118 bits)
opd / CAD13181.1 parathion hydrolase from Sphingobium fuliginis (see paper)
27% identity, 100% coverage of query (117 bits)
4qsfA Crystal structure of amidohydrolase pmi1525 (target efi-500319) from proteus mirabilis hi4320, a complex with butyric acid and manganese
28% identity, 98% coverage of query (117 bits)
8p7qA The impact of molecular variants, crystallization conditions and space group on structure-ligand complexes: a case study on bacterial phosphotriesterase variants and complexes
28% identity, 100% coverage of query (117 bits)
6g0mA Phosphotriesterase pte_c23_7
28% identity, 100% coverage of query (117 bits)
6fweA Phosphotriesterase pte_c23_6
28% identity, 100% coverage of query (117 bits)
6fvkA Phosphotriesterase pte_c23_3
28% identity, 100% coverage of query (117 bits)
6fu6A Phosphotriesterase pte_c23_2
28% identity, 100% coverage of query (116 bits)
F0QXN6 carboxylesterase (EC 3.1.1.1); arylesterase (EC 3.1.1.2); 1,4-lactonase (EC 3.1.1.25); quorum-quenching N-acyl-homoserine lactonase (EC 3.1.1.81); aryldialkylphosphatase (EC 3.1.8.1) from Vulcanisaeta moutnovskia (see 3 papers)
27% identity, 99% coverage of query (114 bits)
4rdzB / F0QXN6 Crystal structure of vmolac in p64 space group (see paper)
27% identity, 99% coverage of query (114 bits)
4e3tB Round 18 arylesterase variant of phosphotriesterase with bound transition state analog
28% identity, 100% coverage of query (114 bits)
4rdyA Crystal structure of vmolac bound to 3-oxo-c10 ahl
27% identity, 98% coverage of query (114 bits)
8p7hA The impact of molecular variants, crystallization conditions and space group on structure-ligand complexes: a case study on bacterial phosphotriesterase variants and complexes
28% identity, 100% coverage of query (114 bits)
6fqeB / P0A434 Phosphotriesterase pte_a53_4
28% identity, 100% coverage of query (113 bits)
6forA Phosphotriesterase pte_a53_6
28% identity, 100% coverage of query (113 bits)
8p7kA The impact of molecular variants, crystallization conditions and space group on structure-ligand complexes: a case study on bacterial phosphotriesterase variants and complexes
28% identity, 100% coverage of query (113 bits)
8p7iA The impact of molecular variants, crystallization conditions and space group on structure-ligand complexes: a case study on bacterial phosphotriesterase variants and complexes
28% identity, 100% coverage of query (113 bits)
6fs3A Phosphotriesterase pte_a53_1
28% identity, 100% coverage of query (113 bits)
6frzA Phosphotriesterase pte_a53_7
28% identity, 100% coverage of query (113 bits)
3urnA Crystal structure of pte mutant h254g/h257w/l303t/k185r/i274n/a80v/s61t with cyclohexyl methylphosphonate inhibitor
28% identity, 100% coverage of query (113 bits)
3a3wA / Q93LD7 Structure of opda mutant (g60a/a80v/s92a/r118q/k185r/q206p/d208g/i260t/g273s) with diethyl 4- methoxyphenyl phosphate bound in the active site (see paper)
29% identity, 98% coverage of query (112 bits)
8p7uA The impact of molecular variants, crystallization conditions and space group on structure-ligand complexes: a case study on bacterial phosphotriesterase variants and complexes
28% identity, 100% coverage of query (112 bits)
5w7hA Supercharged arpte variant r5
29% identity, 98% coverage of query (107 bits)
PFLAC_MYCAP / A5IZ80 Phospho-furanose lactonase; EC 3.1.1.104; EC 3.1.1.25 from Mycoplasmopsis agalactiae (strain NCTC 10123 / CIP 59.7 / PG2) (Mycoplasma agalactiae) (see paper)
A5IZ80 5-phospho-D-xylono-1,4-lactonase (EC 3.1.1.104) from Mycoplasmopsis agalactiae (see paper)
29% identity, 87% coverage of query (104 bits)
PFLAC_MYCS5 / Q4A724 Phospho-furanose lactonase; EC 3.1.1.104; EC 3.1.1.25 from Mycoplasmopsis synoviae (strain 53) (Mycoplasma synoviae) (see paper)
Q4A724 5-phospho-D-xylono-1,4-lactonase (EC 3.1.1.104) from Mycoplasmopsis synoviae (see paper)
28% identity, 97% coverage of query (100 bits)
3ovgA / Q4A724 The crystal structure of an amidohydrolase from mycoplasma synoviae with zn ion bound
28% identity, 97% coverage of query (100 bits)
Q5DQU3 quorum-quenching N-acyl-homoserine lactonase (EC 3.1.1.81) from Rhodococcus erythropolis (see paper)
qsdA / AAT06802.1 QsdA from Rhodococcus erythropolis (see paper)
23% identity, 98% coverage of query (95.9 bits)
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Lawrence Berkeley National Laboratory