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Searching for up to 100 curated homologs for 17726 FitnessBrowser__Keio:17726 (463 a.a.)

Found high-coverage hits (≥70%) to 21 curated proteins.

Removed hits that are identical to the query, leaving 20

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 2.A.1.4.2 / P12681 P-glycerate:Pi antiporter, Pgt from Salmonella typhimurium (see 2 papers)
    33% identity, 96% coverage of query (219 bits)

GlpT / b2240 sn-glycerol 3-phosphate:phosphate antiporter from Escherichia coli K-12 substr. MG1655 (see 24 papers)
glpT / P08194 sn-glycerol 3-phosphate:phosphate antiporter from Escherichia coli (strain K12) (see 48 papers)
TC 2.A.1.4.3 / P08194 Glycerol-P:Pi antiporter (may function by a 'rocker switch' mechanism; Law et al., 2007). The 3-d structure is known (3.3Å resolution) (Huang et al., 2003; Lemieux et al., 2005; Lemieux, 2007) from Escherichia coli (see 7 papers)
    32% identity, 98% coverage of query (218 bits)

Q9HTV5 ABC-type glycerol 3-phosphate transporter (EC 7.6.2.10) from Pseudomonas aeruginosa (see paper)
    32% identity, 98% coverage of query (205 bits)

A0A0H3JLD7 ABC-type glycerol 3-phosphate transporter (EC 7.6.2.10) from Staphylococcus aureus (see paper)
    35% identity, 83% coverage of query (200 bits)

UhpC / b3667 inner membrane protein sensing glucose-6-phosphate from Escherichia coli K-12 substr. MG1655 (see 4 papers)
UHPC_ECOLI / P09836 Membrane sensor protein UhpC from Escherichia coli (strain K12) (see 5 papers)
TC 2.A.1.4.4 / P09836 Hexose-P:Pi antiporter regulatory protein; senses external glucose-6-P and transports it with high affinity and low efficiency from Escherichia coli (see 7 papers)
uhpC regulatory protein UhpC from Escherichia coli K12 (see 7 papers)
uhpC / ECOCYC|GLU-UHPC membrane protein regulates uhpT expression from Escherichia coli K12 (see 2 papers)
    33% identity, 97% coverage of query (192 bits)

TC 2.A.1.4.6 / Q9Z7N9 Glucose-6-P:Pi antiporter, Hpt (may also transport other organophosphates including C3 organophosphates) from Chlamydia pneumoniae (Chlamydophila pneumoniae) (see 3 papers)
    31% identity, 94% coverage of query (191 bits)

TC 2.A.1.4.11 / Q9ZE92 Glycerol-3-phosphate:inorganic phosphate antiporter, GlpT from Rickettsia prowazekii (strain Madrid E)
    31% identity, 90% coverage of query (160 bits)

Build an alignment

Build an alignment for 17726 and 7 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

Q9SA71 ABC-type glycerol 3-phosphate transporter (EC 7.6.2.10) from Arabidopsis thaliana (see paper)
    23% identity, 99% coverage of query (73.2 bits)

G6PT1_HUMAN / O43826 Glucose-6-phosphate exchanger SLC37A4; Glucose-5-phosphate transporter; Glucose-6-phosphate translocase; Solute carrier family 37 member 4; Transformation-related gene 19 protein; TRG-19 from Homo sapiens (Human) (see 24 papers)
TC 2.A.1.4.5 / O43826 Microsomal (ER/Golgi) glucose-6-P:Pi antiporter (glycogen storage disease (GSD1b and 1c); Gierke''s disease protein) (SLC37A2 in mice, associated with white adipose tissue obesity and expressed at high levels in macrophage) (4 isoforms present in humans (Chen et al., 2008)) from Homo sapiens (Human) (see 23 papers)
SLC37A4 / RF|NP_001458.1 glucose-6-phosphate translocase from Homo sapiens
    24% identity, 91% coverage of query (69.7 bits)

GLPT1_ARATH / Q9C5L3 Putative glycerol-3-phosphate transporter 1; G-3-P transporter 1; Glycerol-3-phosphate permease 1; AtG3Pp1; G-3-P permease 1; Protein PHOSPHATE STARVATION-INDUCED GENE 3; AtPS3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9C5L3 ABC-type glycerol 3-phosphate transporter (EC 7.6.2.10) from Arabidopsis thaliana (see paper)
    24% identity, 85% coverage of query (62.0 bits)

GLPT2_ARATH / Q9SB41 Putative glycerol-3-phosphate transporter 2; G-3-P transporter 2; Glycerol-3-phosphate permease 2; AtG3Pp2; G-3-P permease 2; Protein ROOT HAIR SPECIFIC 15; AtRHS15 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9SB41 ABC-type glycerol 3-phosphate transporter (EC 7.6.2.10) from Arabidopsis thaliana (see paper)
    24% identity, 83% coverage of query (57.8 bits)

G6PT3_MOUSE / Q9WU81 Glucose-6-phosphate exchanger SLC37A2; Solute carrier family 37 member 2; cAMP-inducible protein 2 from Mus musculus (Mouse) (see paper)
    23% identity, 92% coverage of query (57.0 bits)

O23596 ABC-type glycerol 3-phosphate transporter (EC 7.6.2.10) from Arabidopsis thaliana (see paper)
    23% identity, 83% coverage of query (56.6 bits)

HSERO_RS23010 D-galacturonate transporter ExuT from Herbaspirillum seropedicae SmR1
    24% identity, 84% coverage of query (56.2 bits)

TC 2.A.1.4.10 / O69759 2-phosphonoacetate/2-phosponopropionate uptake porter of 428 aas, PhnB from Pseudomonas fluorescens
    25% identity, 77% coverage of query (54.3 bits)

G6PT3_HUMAN / Q8TED4 Glucose-6-phosphate exchanger SLC37A2; Solute carrier family 37 member 2 from Homo sapiens (Human) (see paper)
TC 2.A.1.4.8 / Q8TED4 solute carrier family 37 (putative glycerol-3-phosphate transporter), member 2.  Has been shown to catalyze glucose 6-P:Pi antiport across the endoplasmic reticular membrane from Homo sapiens (see 3 papers)
    23% identity, 92% coverage of query (52.8 bits)

YidT / b3691 D-galactonate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 9 papers)
dgoT / P0AA76 D-galactonate:H+ symporter from Escherichia coli (strain K12) (see 11 papers)
DGOT_ECOLI / P0AA76 D-galactonate transporter; D-galactonate/H(+) symporter from Escherichia coli (strain K12) (see 4 papers)
TC 2.A.1.14.7 / P0AA76 Galactonate transporter from Escherichia coli (see 4 papers)
    21% identity, 87% coverage of query (49.7 bits)

PS417_07260 2-deoxy-D-ribonate transporter 2 from Pseudomonas simiae WCS417
    24% identity, 80% coverage of query (48.5 bits)

6e9nA / J7QAK3 E. Coli d-galactonate:proton symporter in the inward open form (see paper)
    21% identity, 83% coverage of query (47.8 bits)

6e9oA E. Coli d-galactonate:proton symporter mutant e133q in the outward substrate-bound form
    22% identity, 84% coverage of query (45.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory