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Searching for up to 100 curated homologs for 17826 FitnessBrowser__Keio:17826 (491 a.a.)

Found high-coverage hits (≥70%) to 8 curated proteins.

Removed hits that are identical to the query, leaving 6

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

ILVC_SALTY / P05989 Ketol-acid reductoisomerase (NADP(+)); KARI; Acetohydroxy-acid isomeroreductase; AHIR; Alpha-keto-beta-hydroxylacyl reductoisomerase; Ketol-acid reductoisomerase type 2; Ketol-acid reductoisomerase type II; EC 1.1.1.86 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
    99% identity, 100% coverage of query (1005 bits)

A6TGG1 ketol-acid reductoisomerase (NADP+) (EC 1.1.1.86) from Klebsiella pneumoniae subsp. pneumoniae (see paper)
    98% identity, 100% coverage of query (970 bits)

A0KS29 ketol-acid reductoisomerase [NAD(P)+] (EC 1.1.1.383) from Shewanella sp. (see paper)
    73% identity, 99% coverage of query (754 bits)

5e4rA / E0SRA9 Crystal structure of domain-duplicated synthetic class ii ketol-acid reductoisomerase 2ia_kari-dd (see paper)
    31% identity, 91% coverage of query (192 bits)

Build an alignment

Build an alignment for 17826 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

3fr8B / Q65XK0 Rice ketolacid reductoisomerase in complex with mg2+-NADPH (see paper)
    26% identity, 73% coverage of query (87.0 bits)

ILV5_ORYSJ / Q65XK0 Ketol-acid reductoisomerase, chloroplastic; Acetohydroxy-acid reductoisomerase; Alpha-keto-beta-hydroxylacyl reductoisomerase; Protein KARI; EC 1.1.1.86 from Oryza sativa subsp. japonica (Rice) (see paper)
Q65XK0 ketol-acid reductoisomerase (NADP+) (EC 1.1.1.86) from Oryza sativa Japonica Group (see paper)
    26% identity, 73% coverage of query (86.7 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory