Searching for up to 100 curated homologs for 17879 FitnessBrowser__Keio:17879 (253 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
Removed hits that are identical to the query, leaving 93
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
BWI76_RS01295 Uridine phosphorylase (EC 2.4.2.3) from Klebsiella michiganensis M5al
97% identity, 100% coverage of query (509 bits)
P0A1F6 uridine phosphorylase (EC 2.4.2.3) from Salmonella enterica subsp. enterica serovar Typhimurium (see 2 papers)
2hn9A / P0A1F6 Crystal structure of the uridine phosphorylase from salmonella typhimurium in complex with thymine and phosphate ion at 2.12a resolution
97% identity, 100% coverage of query (508 bits)
2hwuA Crystal structure of the uridine phosphorylase from salmonella typhimurium in complex with uridine and phosphate ion at 2.91a resolution
97% identity, 100% coverage of query (508 bits)
1rxcA E. Coli uridine phosphorylase: 5-fluorouracil ribose-1-phosphate complex
98% identity, 99% coverage of query (502 bits)
1rxsB E. Coli uridine phosphorylase: 2'-deoxyuridine phosphate complex
98% identity, 99% coverage of query (502 bits)
1u1gA Structure of e. Coli uridine phosphorylase complexed to 5-(m- (benzyloxy)benzyl)barbituric acid (bbba)
98% identity, 99% coverage of query (498 bits)
3kvvA Trapping of an oxocarbenium ion intermediate in up crystals
97% identity, 99% coverage of query (494 bits)
1u1fA Structure of e. Coli uridine phosphorylase complexed to 5-(m- (benzyloxy)benzyl)acyclouridine (bbau)
97% identity, 99% coverage of query (494 bits)
1rxsa E. Coli uridine phosphorylase: 2'-deoxyuridine phosphate complex
97% identity, 99% coverage of query (492 bits)
udp / CAB94934.1 uridine phosphorylase from Yersinia pseudotuberculosis (see paper)
92% identity, 100% coverage of query (490 bits)
1zl2B Crystal structure of the uridine phosphorylase from salmonella typhimurium in complex with 2,2'-anhydrouridine and phosphate ion at 1.85a resolution
94% identity, 99% coverage of query (478 bits)
1y1rB Crystal structure of the uridine phosphorylase from salmonella typhimurium in complex with inhibitor and phosphate ion at 2.11a resolution
94% identity, 99% coverage of query (478 bits)
1y1qC Crystal structure of the uridine phosphorylase from salmonella typhimurium in complex with uridine-5p-monophosphate and sulfate ion at 2.35a resolution
93% identity, 99% coverage of query (473 bits)
Q9K4U1 uridine phosphorylase (EC 2.4.2.3) from Vibrio cholerae (see 2 papers)
5efoB / Q9K4U1 X-ray structure uridine phosphorylase from vibrio cholerae in complex with cytidine and cytosine at 1.63a.
udp / CAB94933.1 uridine phosphorylase from Vibrio cholerae (see paper)
75% identity, 100% coverage of query (409 bits)
6rcaA X-ray structure uridine phosphorylase from vibrio cholerae in complex with 2.2'-anhydrouridine at 1.34 a
76% identity, 98% coverage of query (409 bits)
5efoE X-ray structure uridine phosphorylase from vibrio cholerae in complex with cytidine and cytosine at 1.63a.
76% identity, 98% coverage of query (409 bits)
5c80A X-ray structure uridine phosphorylase from vibrio cholerae in complex with uridine at 2.24 a resolution
76% identity, 98% coverage of query (409 bits)
4k6oA X-ray structure uridine phosphorylase from vibrio cholerae in complex with 6-methyluracil at 1.17 a resolution
76% identity, 98% coverage of query (408 bits)
Shewana3_3680 Uridine phosphorylase (EC 2.4.2.3) from Shewanella sp. ANA-3
76% identity, 99% coverage of query (403 bits)
Sama_0412 Uridine phosphorylase (EC 2.4.2.3) from Shewanella amazonensis SB2B
79% identity, 99% coverage of query (402 bits)
4oglA X-ray structure uridine phosphorylase from vibrio cholerae in complex with thymine at 1.25 a resolution
75% identity, 98% coverage of query (402 bits)
4r2wD / Q8E9X9 X-ray structure of uridine phosphorylase from shewanella oneidensis mr-1 in complex with uridine at 1.6 a resolution (see paper)
76% identity, 99% coverage of query (399 bits)
SO4133 Uridine phosphorylase (EC 2.4.2.3) from Shewanella oneidensis MR-1
C7EWM3 uridine phosphorylase (EC 2.4.2.3) from Shewanella oneidensis (see 4 papers)
76% identity, 99% coverage of query (399 bits)
4u2kB X-ray structure uridine phosphorylase from vibrio cholerae in complex with anticancer compound at 2.13 a resolution
75% identity, 98% coverage of query (395 bits)
3pnsB Crystal structure of uridine phosphorylase complexed with uracil from vibrio cholerae o1 biovar el tor
75% identity, 98% coverage of query (395 bits)
4u2kD X-ray structure uridine phosphorylase from vibrio cholerae in complex with anticancer compound at 2.13 a resolution
74% identity, 98% coverage of query (392 bits)
4yjkA Crystal structure of c212s mutant of shewanella oneidensis mr-1 uridine phosphorylase
74% identity, 99% coverage of query (383 bits)
4r2wF X-ray structure of uridine phosphorylase from shewanella oneidensis mr-1 in complex with uridine at 1.6 a resolution
74% identity, 99% coverage of query (381 bits)
TK1479 / Q5JJC1 uridine phosphorylase (EC 2.4.2.2) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (see paper)
UDP_THEKO / Q5JJC1 Uridine phosphorylase; UPase; UrdPase; EC 2.4.2.3 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
45% identity, 95% coverage of query (206 bits)
Q5XA29 pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) from Streptococcus pyogenes (see paper)
40% identity, 98% coverage of query (179 bits)
3qpbC / Q5XA29 Crystal structure of streptococcus pyogenes uridine phosphorylase reveals a subclass of the np-i superfamily (see paper)
40% identity, 98% coverage of query (178 bits)
B9LS20 guanosine phosphorylase (EC 2.4.2.15) from Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34) (see paper)
36% identity, 97% coverage of query (161 bits)
Q9YA34 uridine phosphorylase (EC 2.4.2.3) from Aeropyrum pernix (see 2 papers)
41% identity, 94% coverage of query (160 bits)
4mchA / Q5E046 Crystal structure of uridine phosphorylase from vibrio fischeri es114 complexed with 6-hydroxy-1-naphthoic acid, nysgrc target 029520.
31% identity, 85% coverage of query (118 bits)
1jdvC / P50389 Crystal structure of 5'-deoxy-5'-methylthioadenosine phosphorylase complexed with adenosine and sulfate ion (see paper)
32% identity, 77% coverage of query (112 bits)
PNPH_SACS2 / P50389 Purine nucleoside phosphorylase; PNP; 5'-methylthioadenosine phosphorylase I; MTA phosphorylase I; MTAPI; EC 2.4.2.1; EC 2.4.2.28 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
P50389 S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) from Saccharolobus solfataricus (see 4 papers)
32% identity, 77% coverage of query (112 bits)
1je1A 5'-deoxy-5'-methylthioadenosine phosphorylase complex with guanosine and sulfate
32% identity, 85% coverage of query (112 bits)
1jdzA Crystal structure of 5'-deoxy-5'-methylthioadenosine phosphorylase with formycin b and sulfate ion
32% identity, 81% coverage of query (112 bits)
1jdvA Crystal structure of 5'-deoxy-5'-methylthioadenosine phosphorylase complexed with adenosine and sulfate ion
32% identity, 77% coverage of query (112 bits)
1jdsA 5'-deoxy-5'-methylthioadenosine phosphorylase complex with phosphate (space group p21)
32% identity, 77% coverage of query (112 bits)
1jdtA Crystal structure of 5'-deoxy-5'-methylthioadenosine phosphorylase complexed with mta and sulfate ion
32% identity, 77% coverage of query (112 bits)
PNPH_PLAVS / A5K9M4 Purine nucleoside phosphorylase; PvPNP; EC 2.4.2.1 from Plasmodium vivax (strain Salvador I) (see paper)
30% identity, 97% coverage of query (111 bits)
Q72IR2 purine-nucleoside phosphorylase (EC 2.4.2.1) from Thermus thermophilus (see 2 papers)
31% identity, 89% coverage of query (109 bits)
1odiA / Q5SID9 Purine nucleoside phosphorylase from thermus thermophilus (see paper)
31% identity, 89% coverage of query (109 bits)
1odjA Purine nucleoside phosphorylase from thermus thermophilus
31% identity, 89% coverage of query (109 bits)
Build an alignment for 17879 and 45 homologs with ≥ 30% identity
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3enzC / Q8I3X4 Arsenolytic structure of plasmodium falciparum purine nucleoside phosphorylase with hypoxanthine, ribose and arsenate ion (see paper)
29% identity, 97% coverage of query (108 bits)
PNP / Q8T9Z7 purine nucleoside phosphorylase monomer (EC 2.4.2.44; EC 2.4.2.1) from Plasmodium falciparum (see 3 papers)
PNPH_PLAF7 / Q8I3X4 Purine nucleoside phosphorylase; PfPNP; S-methyl-5'-thioinosine phosphorylase; EC 2.4.2.1; EC 2.4.2.44 from Plasmodium falciparum (isolate 3D7) (see 6 papers)
PNPH_PLAFA / Q8T9Z7 Purine nucleoside phosphorylase; S-methyl-5'-thioinosine phosphorylase; EC 2.4.2.1; EC 2.4.2.44 from Plasmodium falciparum (see 2 papers)
Q8I3X4 purine-nucleoside phosphorylase (EC 2.4.2.1); uridine phosphorylase (EC 2.4.2.3) from Plasmodium falciparum (see 3 papers)
Q8T9Z7 purine-nucleoside phosphorylase (EC 2.4.2.1) from Plasmodium falciparum (see 5 papers)
28% identity, 97% coverage of query (108 bits)
3phcA Crystal structure of plasmodium falciparum purine nucleoside phosphorylase in complex with dadme-immg
28% identity, 97% coverage of query (108 bits)
1q1gA Crystal structure of plasmodium falciparum pnp with 5'-methylthio- immucillin-h
28% identity, 97% coverage of query (108 bits)
1nw4A Crystal structure of plasmodium falciparum purine nucleoside phosphorylase in complex with immh and sulfate
28% identity, 97% coverage of query (108 bits)
5zncA Plasmodium falciparum purine nucleoside phosphorylase in complex with quinine
28% identity, 97% coverage of query (108 bits)
8w7hA Purine nucleoside phosphorylase in complex with mmv000848
28% identity, 97% coverage of query (107 bits)
1sq6A Plasmodium falciparum homolog of uridine phosphorylase/purine nucleoside phosphorylase
29% identity, 87% coverage of query (107 bits)
5zniA Plasmodium falciparum purine nucleoside phosphorylase in complex with mefloquine
30% identity, 78% coverage of query (106 bits)
2bsxA Crystal structure of the plasmodium falciparum purine nucleoside phosphorylase complexed with inosine
29% identity, 82% coverage of query (106 bits)
2iscD / A2E7Y6 Crystal structure of purine nucleoside phosphorylase from trichomonas vaginalis with dadme-imm-a (see paper)
30% identity, 92% coverage of query (93.6 bits)
1ovgA M64v pnp +mepdr
28% identity, 91% coverage of query (92.0 bits)
1ov6A M64v pnp + allo
28% identity, 91% coverage of query (92.0 bits)
1oumA M64v pnp +talo
28% identity, 91% coverage of query (92.0 bits)
Pup / b4384 purine nucleoside phosphorylase (EC 2.4.2.15; EC 2.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
deoD / P0ABP8 purine nucleoside phosphorylase (EC 2.4.2.15; EC 2.4.2.1) from Escherichia coli (strain K12) (see 30 papers)
DEOD_ECOLI / P0ABP8 Purine nucleoside phosphorylase DeoD-type; PNP; EC 2.4.2.1 from Escherichia coli (strain K12) (see 5 papers)
deoD / RF|NP_418801 purine nucleoside phosphorylase deoD-type; EC 2.4.2.1 from Escherichia coli K12 (see 13 papers)
28% identity, 91% coverage of query (91.3 bits)
5iu6A Crystal structure of e.Coli purine nucleoside phosphorylase with 7- deazahypoxanthine
28% identity, 91% coverage of query (91.3 bits)
5i3cA Crystal structure of e.Coli purine nucleoside phosphorylase with acycloguanosine
28% identity, 91% coverage of query (91.3 bits)
3ut6A Crystal structure of e. Coli pnp complexed with po4 and formycin a
28% identity, 91% coverage of query (91.3 bits)
1pw7A Crystal structure of e. Coli purine nucleoside phosphorylase complexed with 9-beta-d-arabinofuranosyladenine and sulfate/phosphate
28% identity, 91% coverage of query (91.3 bits)
1pr0A Escherichia coli purine nucleoside phosphorylase complexed with inosine and phosphate/sulfate
28% identity, 91% coverage of query (91.3 bits)
1pkeA Crystal structure of e. Coli purine nucleoside phosphorylase complexed with 2-fluoro-2'-deoxyadenosine and sulfate/phosphate
28% identity, 91% coverage of query (91.3 bits)
1pk9A Crystal structure of e. Coli purine nucleoside phosphorylase complexed with 2-fluoroadenosine and sulfate/phosphate
28% identity, 91% coverage of query (91.3 bits)
1pk7A Crystal structure of e. Coli purine nucleoside phosphorylase complexed with adenosine and sulfate/phosphate
28% identity, 91% coverage of query (91.3 bits)
1otyA Native pnp +allo
28% identity, 91% coverage of query (91.3 bits)
1k9sD Purine nucleoside phosphorylase from e. Coli in complex with formycin a derivative and phosphate
28% identity, 91% coverage of query (91.3 bits)
1k9sA Purine nucleoside phosphorylase from e. Coli in complex with formycin a derivative and phosphate
28% identity, 91% coverage of query (91.3 bits)
1a69A Purine nucleoside phosphorylase in complex with formycin b and sulphate (phosphate)
28% identity, 91% coverage of query (91.3 bits)
P0ABP9 Purine nucleoside phosphorylase DeoD-type; PNP; EC 2.4.2.1 from Escherichia coli O157:H7
28% identity, 91% coverage of query (91.3 bits)
1pr4A Escherichia coli purine nucleoside phosphorylase complexed with 9- beta-d-ribofuranosyl-6-methylthiopurine and phosphate/sulfate
27% identity, 91% coverage of query (90.1 bits)
1z39A Crystal structure of trichomonas vaginalis purine nucleoside phosphorylase complexed with 2'-deoxyinosine
30% identity, 92% coverage of query (89.7 bits)
1z38A Crystal structure of trichomonas vaginalis purine nucleoside phosphorylase complexed with inosine
30% identity, 92% coverage of query (89.7 bits)
1z37A Crystal structure of trichomonas vaginalis purine nucleoside phosphorylase complexed with adenosine
30% identity, 92% coverage of query (89.7 bits)
1z36A Crystal structure of trichomonas vaginalis purine nucleoside phosphorylase complexed with formycin a
30% identity, 92% coverage of query (89.7 bits)
1z35A Crystal structure of trichomonas vaginalis purine nucleoside phosphorylase complexed with 2-fluoroadenosine
30% identity, 92% coverage of query (89.7 bits)
1z34A Crystal structure of trichomonas vaginalis purine nucleoside phosphorylase complexed with 2-fluoro-2'-deoxyadenosine
30% identity, 92% coverage of query (89.7 bits)
C8CPR9 purine-nucleoside phosphorylase (EC 2.4.2.1) from Pseudoalteromonas sp. (see paper)
28% identity, 91% coverage of query (88.2 bits)
1pr6A Escherichia coli purine nucleoside phosphorylase complexed with 9- beta-d-xylofuranosyladenine and phosphate/sulfate
29% identity, 77% coverage of query (88.2 bits)
1pr5A Escherichia coli purine nucleoside phosphorylase complexed with 7- deazaadenosine and phosphate/sulfate
29% identity, 77% coverage of query (88.2 bits)
2i4tA Crystal structure of purine nucleoside phosphorylase from trichomonas vaginalis with imm-a
30% identity, 92% coverage of query (87.0 bits)
DEOD_SALTY / Q8ZJV7 Purine nucleoside phosphorylase DeoD-type; PNP; EC 2.4.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
28% identity, 91% coverage of query (86.3 bits)
O34925 purine-nucleoside phosphorylase (EC 2.4.2.1) from Bacillus subtilis (see paper)
31% identity, 81% coverage of query (85.9 bits)
4daeA / O34925 Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with 6-chloroguanosine (see paper)
31% identity, 81% coverage of query (85.5 bits)
4danA Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with 2-fluoroadenosine
31% identity, 81% coverage of query (85.5 bits)
4darA Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with tubercidin
31% identity, 81% coverage of query (85.5 bits)
4dabA Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with hypoxanthine
31% identity, 81% coverage of query (85.5 bits)
4da8A Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with 8-bromoguanosine
31% identity, 81% coverage of query (85.5 bits)
4da7A Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with aciclovir
31% identity, 81% coverage of query (85.5 bits)
4da6A Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with ganciclovir
31% identity, 81% coverage of query (85.5 bits)
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Lawrence Berkeley National Laboratory