Searching for up to 100 curated homologs for 17923 FitnessBrowser__Keio:17923 (298 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
Removed hits that are identical to the query, leaving 97
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
7aghA Crystal structure of sf kinase yihv from e. Coli in complex with amppnp-mg
99% identity, 100% coverage of query (583 bits)
8cqxA / A0A0B0SD75 Ribokinase from t.Sp mutant a92g
32% identity, 98% coverage of query (112 bits)
Build an alignment for 17923 and 2 homologs with ≥ 30% identity
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deoK / Q8XGW5 deoxyribokinase monomer (EC 2.7.1.229) from Salmonella typhi (see 4 papers)
29% identity, 98% coverage of query (110 bits)
AO356_00950 Ribokinase (EC 2.7.1.15) from Pseudomonas fluorescens FW300-N2C3
29% identity, 98% coverage of query (106 bits)
6znxC / A0A0B0SD75 Ribokinase from thermus species
32% identity, 88% coverage of query (100 bits)
RBSK_LEIMA / E9AD19 Ribokinase; RK; EC 2.7.1.15 from Leishmania major (see paper)
30% identity, 95% coverage of query (99.4 bits)
BT2803 ribokinase (EC 2.7.1.15) from Bacteroides thetaiotaomicron VPI-5482
32% identity, 95% coverage of query (98.2 bits)
RBSK_STAAC / A0A0H2WZY4 Ribokinase; RK; EC 2.7.1.15 from Staphylococcus aureus (strain COL) (see paper)
A0A0H2WZY4 ribokinase (EC 2.7.1.15) from Staphylococcus aureus (see paper)
27% identity, 97% coverage of query (97.4 bits)
6a8aA / A0A3S7X0F5 Ribokinase from leishmania donovani with atp (see paper)
30% identity, 95% coverage of query (96.7 bits)
6a8cA Ribokinase from leishmania donovani with adp
30% identity, 95% coverage of query (96.7 bits)
6a8bA Ribokinase from leishmania donovani with amppcp
30% identity, 95% coverage of query (96.7 bits)
A0A0H2UL04 ribokinase (EC 2.7.1.15) from Vibrio cholerae (see paper)
31% identity, 99% coverage of query (96.3 bits)
4xckA / A0A0H2UL04 Vibrio cholerae o395 ribokinase complexed with adp, ribose and cesium ion. (see paper)
31% identity, 99% coverage of query (96.3 bits)
Q9LNE4 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
29% identity, 93% coverage of query (94.0 bits)
STM4066 / Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
AIRSK_SALTY / Q8ZKR2 Aminoimidazole riboside kinase; AIRs kinase; EC 2.7.1.223 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella enterica subsp. enterica serovar Typhimurium (see 2 papers)
27% identity, 96% coverage of query (94.0 bits)
5c41A / Q9H477 Crystal structure of human ribokinase in complex with amppcp in p21 spacegroup and with 4 protomers
30% identity, 95% coverage of query (93.2 bits)
6wk0B Crystal structure of human ribokinase in complex with amppcp and ribose
30% identity, 95% coverage of query (93.2 bits)
5c3yA Structure of human ribokinase crystallized with amppnp
30% identity, 95% coverage of query (93.2 bits)
2fv7A Crystal structure of human ribokinase
30% identity, 95% coverage of query (93.2 bits)
6wjzA Crystal structure of human ribokinase in complex with ampcp
30% identity, 95% coverage of query (92.8 bits)
5byfA Crystal structure of human ribokinase in complex with amp
30% identity, 93% coverage of query (90.5 bits)
RBSK_HUMAN / Q9H477 Ribokinase; RK; EC 2.7.1.15 from Homo sapiens (Human) (see paper)
Q9H477 ribokinase (EC 2.7.1.15) from Homo sapiens (see paper)
30% identity, 93% coverage of query (90.1 bits)
1tz6A Crystal structure of aminoimidazole riboside kinase from salmonella enterica complexed with aminoimidazole riboside and atp analog
29% identity, 89% coverage of query (90.1 bits)
1tz3A / Q8ZKR2 Crystal structure of aminoimidazole riboside kinase complexed with aminoimidazole riboside (see paper)
29% identity, 89% coverage of query (89.7 bits)
Q9SID0 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
28% identity, 93% coverage of query (89.0 bits)
O04897 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
28% identity, 98% coverage of query (88.6 bits)
BT2804 ribokinase (EC 2.7.1.15) from Bacteroides thetaiotaomicron VPI-5482
29% identity, 98% coverage of query (88.6 bits)
SCRK1_ORYSI / A2WXV8 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
28% identity, 90% coverage of query (88.6 bits)
BWI76_RS00290 Ribokinase (EC 2.7.1.15) from Klebsiella michiganensis M5al
29% identity, 98% coverage of query (88.2 bits)
Pf1N1B4_6031 Ribokinase (EC 2.7.1.15) from Pseudomonas fluorescens FW300-N1B4
29% identity, 98% coverage of query (88.2 bits)
6ilsB / A1A6H3 Structure of arabidopsis thaliana ribokinase complexed with ribose and atp (see paper)
29% identity, 98% coverage of query (87.8 bits)
scrK / P26420 fructokinase (EC 2.7.1.4) from Klebsiella pneumoniae (see paper)
SCRK_KLEPN / P26420 Fructokinase; EC 2.7.1.4 from Klebsiella pneumoniae (see paper)
scrK / GB|CAA43322.1 fructokinase; EC 2.7.1.4 from Klebsiella pneumoniae (see paper)
scrK / CAA43322.1 fructokinase from Klebsiella pneumoniae (see paper)
31% identity, 81% coverage of query (87.4 bits)
RBSK / A1A6H3 ribokinase (EC 2.7.1.15) from Arabidopsis thaliana (see 2 papers)
RBSK_ARATH / A1A6H3 Ribokinase; AtRBSK; RK; EC 2.7.1.15 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
A1A6H3 ribokinase (EC 2.7.1.15) from Arabidopsis thaliana (see paper)
28% identity, 99% coverage of query (87.0 bits)
Q9M1B9 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
28% identity, 93% coverage of query (86.7 bits)
SCRK1_MAIZE / Q6XZ79 Fructokinase-1; ZmFRK1; EC 2.7.1.4 from Zea mays (Maize)
28% identity, 90% coverage of query (86.7 bits)
RBSKI_FRUSL / P83534 Bifunctional ribokinase/ribose-5-phosphate isomerase A; EC 2.7.1.15; EC 5.3.1.6 from Fructilactobacillus sanfranciscensis (strain ATCC 27651 / DSM 20451 / JCM 5668 / CCUG 30143 / KCTC 3205 / NCIMB 702811 / NRRL B-3934 / L-12) (Lactobacillus sanfranciscensis) (see paper)
28% identity, 96% coverage of query (85.9 bits)
SCRK1_ORYSJ / Q0JGZ6 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. japonica (Rice) (see paper)
27% identity, 90% coverage of query (85.5 bits)
N515DRAFT_1919 Fructokinase (EC 2.7.1.4) from Dyella japonica UNC79MFTsu3.2
26% identity, 98% coverage of query (84.7 bits)
1gqtB / P0A9J6 Activation of ribokinase by monovalent cations (see paper)
30% identity, 95% coverage of query (84.0 bits)
RbsK / b3752 ribokinase (EC 2.7.1.15) from Escherichia coli K-12 substr. MG1655 (see 20 papers)
rbsK / P0A9J6 ribokinase (EC 2.7.1.15) from Escherichia coli (strain K12) (see 19 papers)
RBSK_ECOLI / P0A9J6 Ribokinase; RK; EC 2.7.1.15 from Escherichia coli (strain K12) (see 5 papers)
rbsK / RF|NP_418208 ribokinase from Escherichia coli K12 (see 4 papers)
30% identity, 95% coverage of query (84.0 bits)
1rk2A E. Coli ribokinase complexed with ribose and adp, solved in space group p212121
30% identity, 95% coverage of query (84.0 bits)
Q42645 fructokinase (EC 2.7.1.4) from Beta vulgaris (see paper)
27% identity, 90% coverage of query (82.8 bits)
P37829 fructokinase (EC 2.7.1.4) from Solanum tuberosum (see 2 papers)
27% identity, 93% coverage of query (82.0 bits)
AO353_20835 Ribokinase (EC 2.7.1.15) from Pseudomonas fluorescens FW300-N2E3
30% identity, 98% coverage of query (80.9 bits)
Q42896 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
26% identity, 93% coverage of query (80.9 bits)
SMc01103 Ribokinase (EC 2.7.1.15) from Sinorhizobium meliloti 1021
26% identity, 92% coverage of query (79.7 bits)
O82616 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
26% identity, 90% coverage of query (79.0 bits)
5eynA Crystal structure of fructokinase from vibrio cholerae o395 in fructose, adp, beryllium trifluoride and calcium ion bound form
26% identity, 89% coverage of query (79.0 bits)
A0A0H3AER7 fructokinase (EC 2.7.1.4) from Vibrio cholerae (see paper)
26% identity, 89% coverage of query (78.6 bits)
SCRK2_ORYSI / A2YQL4 Fructokinase-2; Fructokinase II; OsFKII; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
SCRK2_ORYSJ / Q0J8G4 Fructokinase-2; Fructokinase II; OsFKII; EC 2.7.1.4 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
A2YQL4 fructokinase (EC 2.7.1.4) from Oryza sativa (see paper)
28% identity, 95% coverage of query (78.2 bits)
scrK / Q9ZHJ6 fructokinase (EC 2.7.1.4) from Clostridium beijerinckii (see paper)
26% identity, 96% coverage of query (77.8 bits)
5yggA / A0A0H3AER7 Crystal structure of fructokinase double-mutant (t261c-h108c) from vibrio cholerae o395 in fructose, adp and potassium ion bound form (see paper)
26% identity, 89% coverage of query (76.3 bits)
HSERO_RS11500 Ribokinase (EC 2.7.1.15) from Herbaspirillum seropedicae SmR1
27% identity, 96% coverage of query (75.9 bits)
Q9FLH8 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
25% identity, 98% coverage of query (75.5 bits)
Q9C524 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
28% identity, 95% coverage of query (75.5 bits)
cscK / GB|CAA57218.2 fructokinase; EC 2.7.1.4 from Escherichia coli (see paper)
27% identity, 91% coverage of query (74.3 bits)
SCRK2_MAIZE / Q6XZ78 Fructokinase-2; ZmFRK2; EC 2.7.1.4 from Zea mays (Maize)
28% identity, 95% coverage of query (74.3 bits)
Q9YG89 6-phosphofructokinase (EC 2.7.1.11) from Aeropyrum pernix (see 2 papers)
26% identity, 95% coverage of query (73.2 bits)
scrK / GB|AAA08602.1 fructokinase; EC 2.7.1.4 from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
scrK / CAA43323.1 fructokinase from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
28% identity, 93% coverage of query (72.4 bits)
8omeA / P50053 Crystal structure of hkhk-a in complex with compound-4 (see paper)
25% identity, 92% coverage of query (72.0 bits)
BPHYT_RS25805 deoxyribose kinase (EC 2.7.1.15) from Burkholderia phytofirmans PsJN
27% identity, 98% coverage of query (71.6 bits)
KHK_RAT / Q02974 Ketohexokinase; Hepatic fructokinase; EC 2.7.1.3 from Rattus norvegicus (Rat) (see 2 papers)
Q02974 ketohexokinase (EC 2.7.1.3) from Rattus norvegicus (see paper)
25% identity, 93% coverage of query (71.6 bits)
2hw1A Crystal structure of human ketohexokinase complexed to different sugar molecules
25% identity, 92% coverage of query (71.6 bits)
Q8NQR0 ribokinase (EC 2.7.1.15) from Corynebacterium glutamicum (see paper)
29% identity, 95% coverage of query (70.9 bits)
3ikhA / A6T989 Crystal structure of ribokinase in complex with atp and glycerol in the active site from klebsiella pneumoniae
27% identity, 86% coverage of query (69.7 bits)
F8D4I6 α-D-ribose-1-phosphate 5-kinase (ATP) (EC 2.7.1.239) from Halopiger xanaduensis (strain DSM 18323 / JCM 14033 / SH-6) (see 2 papers)
28% identity, 99% coverage of query (69.7 bits)
3i3yD Crystal structure of ribokinase in complex with d-ribose from klebsiella pneumoniae
27% identity, 86% coverage of query (69.7 bits)
P97328 ketohexokinase (EC 2.7.1.3) from Mus musculus (see 2 papers)
25% identity, 92% coverage of query (69.3 bits)
8omdA / P97328 Crystal structure of mkhk in complex with compound-4 (see paper)
25% identity, 92% coverage of query (69.3 bits)
6p2dA Structure of mouse ketohexokinasE-C in complex with fructose and adp
25% identity, 92% coverage of query (69.3 bits)
KHK / P50053 Ketohexokinase (EC 2.7.1.3) from Homo sapiens (see 8 papers)
KHK_HUMAN / P50053 Ketohexokinase; Hepatic fructokinase; EC 2.7.1.3 from Homo sapiens (Human) (see 4 papers)
P50053 ketohexokinase (EC 2.7.1.3) from Homo sapiens (see 6 papers)
24% identity, 92% coverage of query (68.6 bits)
RBSK_SCHPO / O60116 Ribokinase; RK; EC 2.7.1.15 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
25% identity, 96% coverage of query (68.6 bits)
6ul7A Structure of human ketohexokinasE-C in complex with fructose, no3, and osthole
24% identity, 92% coverage of query (68.6 bits)
3qa2A X-ray structure of ketohexokinase in complex with a pyrimidopyrimidine analog 2
24% identity, 92% coverage of query (68.6 bits)
8ug1B / P50053 Crystal structure of khk-c and compound 13 (see paper)
24% identity, 92% coverage of query (68.2 bits)
8ug3A Crystal structure of khk-c and compound 23
24% identity, 92% coverage of query (68.2 bits)
8omkA Hkhk-c in complex with adp & fructose 1-phosphate
24% identity, 92% coverage of query (68.2 bits)
8omfA Crystal structure of hkhk-c in complex with compound-4
24% identity, 92% coverage of query (68.2 bits)
6w0zA Structure of khk in complex with compound 8 (2-[(1~{s},5~{r})-3-[2- [(2~{s})-2-methylazetidin-1-yl]-6-(trifluoromethyl)pyrimidin-4-yl]-3- azabicyclo[3.1.0]hexan-6-yl]ethanoic acid)
24% identity, 92% coverage of query (68.2 bits)
6w0yA Structure of khk in complex with compound 6 (2-[(1~{r},5~{s})-3-[5- cyano-6-[(2~{s},3~{r})-2-methyl-3-oxidanyl-azetidin-1-yl]-4- (trifluoromethyl)pyridin-2-yl]-3-azabicyclo[3.1.0]hexan-6-yl]ethanoic acid)
24% identity, 92% coverage of query (68.2 bits)
6w0xA Structure of khk in complex with compound 4 (6-[(1~{s},5~{r})-6- (hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-[(2~{s},3~{r})-2- methyl-3-oxidanyl-azetidin-1-yl]-4-(trifluoromethyl)pyridine-3- carbonitrile)
24% identity, 92% coverage of query (68.2 bits)
6w0wA Structure of khk in complex with compound 3
24% identity, 92% coverage of query (68.2 bits)
6w0nA Structure of khk in complex with compound 2
24% identity, 92% coverage of query (68.2 bits)
5wbzA Structure of human ketohexokinase complexed with hits from fragment screening
24% identity, 92% coverage of query (68.2 bits)
5wbrA Structure of human ketohexokinase complexed with hits from fragment screening
24% identity, 92% coverage of query (68.2 bits)
5wbqA Structure of human ketohexokinase complexed with hits from fragment screening
24% identity, 92% coverage of query (68.2 bits)
5wbpA Structure of human ketohexokinase complexed with hits from fragment screening
24% identity, 92% coverage of query (68.2 bits)
5wboA Structure of human ketohexokinase complexed with hits from fragment screening
24% identity, 92% coverage of query (68.2 bits)
5wbmA Structure of human ketohexokinase complexed with hits from fragment screening
24% identity, 92% coverage of query (68.2 bits)
3ro4A X-ray structure of ketohexokinase in complex with an indazole compound derivative
24% identity, 92% coverage of query (68.2 bits)
3qaiA X-ray structure of ketohexokinase in complex with a pyrimidopyrimidine analog 3
24% identity, 92% coverage of query (68.2 bits)
3q92A X-ray structure of ketohexokinase in complex with a pyrimidopyrimidine analog 1
24% identity, 92% coverage of query (68.2 bits)
3ncaA X-ray structure of ketohexokinase in complex with a thieno pyridinol compound
24% identity, 92% coverage of query (68.2 bits)
3nc9A X-ray structure of ketohexokinase complexed with an indazole compound
24% identity, 92% coverage of query (68.2 bits)
3nc2A X-ray structure of ketohexokinase with a quinazoline
24% identity, 92% coverage of query (68.2 bits)
3nbwA X-ray structure of ketohexokinase in complex with a pyrazole compound
24% identity, 92% coverage of query (68.2 bits)
3nbvA X-ray structure of ketohexokinase in complex with amp-pnp and fructose
24% identity, 92% coverage of query (68.2 bits)
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