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Searching for up to 100 curated homologs for 18220 FitnessBrowser__Keio:18220 (154 a.a.)

Found high-coverage hits (≥70%) to 11 curated proteins.

Removed hits that are identical to the query, leaving 10

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

CmtB / b2934 mannitol-specific PTS enzyme IIA component CmtB (EC 2.7.1.197) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
CmtB / P69824 mannitol-specific PTS enzyme IIA component CmtB (EC 2.7.1.197) from Escherichia coli (strain K12) (see 2 papers)
    40% identity, 78% coverage of query (91.7 bits)

Build an alignment

Build an alignment for 18220 and 1 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

SgaR2 / VIMSS5937003 SgaR2 regulator of Ascorbate utilization, effector SgaB2, ascorbate-specific PTS system, EIIB component; HPr, phosphocarrier protein from Streptococcus uberis 0140J
    28% identity, 90% coverage of query (88.6 bits)

SgaR2 / VIMSS7471841 SgaR2 regulator of Ascorbate utilization, effector SgaB2, ascorbate-specific PTS system, EIIB component; HPr, phosphocarrier protein from Streptococcus dysgalactiae subsp. equisimilis GGS_124
    30% identity, 87% coverage of query (87.0 bits)

SgaR2 / VIMSS3591184 SgaR2 regulator of Ascorbate utilization, effector SgaB2, ascorbate-specific PTS system, EIIB component; HPr, phosphocarrier protein from Streptococcus suis 05ZYH33
    31% identity, 93% coverage of query (84.0 bits)

SgaR2 / VIMSS5803672 SgaR2 regulator of Ascorbate utilization, effector SgaB2, ascorbate-specific PTS system, EIIB component; HPr, phosphocarrier protein from Streptococcus equi subsp. zooepidemicus MGCS10565
    28% identity, 92% coverage of query (82.8 bits)

SgaR2 / VIMSS10161800 SgaR2 regulator of Ascorbate utilization, effector SgaB2, ascorbate-specific PTS system, EIIB component; HPr, phosphocarrier protein from Streptococcus mitis B6
    30% identity, 73% coverage of query (77.4 bits)

1j6tA / P00550 Complex of enzyme iiamtl and the histidine-containing phosphocarrier protein hpr from escherichia coli nmr, restrained regularized mean structure (see paper)
    34% identity, 91% coverage of query (60.5 bits)

MtlC / b3599 mannitol-specific PTS enzyme IICBA component (EC 2.7.1.197; EC 2.7.1.198) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
mtlA / P00550 mannitol-specific PTS enzyme IICBA component (EC 2.7.1.197; EC 2.7.1.198) from Escherichia coli (strain K12) (see 24 papers)
PTM3C_ECOLI / P00550 PTS system mannitol-specific EIICBA component; EIICBA-Mtl; EII-Mtl; EC 2.7.1.197 from Escherichia coli (strain K12) (see 6 papers)
P00550 protein-Npi-phosphohistidine-D-mannitol phosphotransferase (EC 2.7.1.197) from Escherichia coli (see 7 papers)
TC 4.A.2.1.2 / P00550 Mannitol porter (MtlA) (mannitol-1-P forming), the mannitol IICBA complex from Escherichia coli (see 9 papers)
mtlA / GB|AAC76623.1 PTS system mannitol-specific EIICBA component; EC 2.7.1.-; EC 2.7.1.69 from Escherichia coli K12 (see 9 papers)
    34% identity, 91% coverage of query (59.7 bits)

TC 4.A.2.1.12 / Q9KKQ7 The mannitol/glucitol transporter, MtlA (IICBAMtl) from Vibrio cholerae (see paper)
    26% identity, 94% coverage of query (52.0 bits)

PtsN / b3204 phosphotransferase system enzyme IIA(Ntr) from Escherichia coli K-12 substr. MG1655 (see 22 papers)
ptsN / AAB60165.1 Enzyme IIANtr from Escherichia coli (see 3 papers)
    26% identity, 95% coverage of query (49.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory