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Searching for up to 100 curated homologs for 18264 FitnessBrowser__Keio:18264 (551 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

Removed hits that are identical to the query, leaving 99

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

BAB38639.1 trehalose 6-P hydrolase (ECs5216) (EC 3.2.1.93) (see protein)
    99% identity, 100% coverage of query (1140 bits)

BAG86620.1 trehalose-6-phosphate hydrolase (TreC;KP1_0530) (EC 3.2.1.93) (see protein)
    82% identity, 100% coverage of query (961 bits)

bsPTRE / BAE45038.1 trehalose-6-phosphate hydrolase from Geobacillus stearothermophilus (see paper)
    57% identity, 99% coverage of query (654 bits)

AAF71997.1 α-glucosidase (EC 3.2.1.20) (see protein)
    57% identity, 99% coverage of query (649 bits)

Q65MI2 alpha,alpha-phosphotrehalase (EC 3.2.1.93) from Bacillus licheniformis (see 2 papers)
AAU39732.1 trehalose-6-P hydrolase (TreA;BlTreA;BLi00797;BL03069) (EC 3.2.1.93) (see protein)
    60% identity, 91% coverage of query (640 bits)

5brpA / Q65MI2 Crystal structure of bacillus licheniformis trehalose-6-phosphate hydrolase (trea), mutant r201q, in complex with png (see paper)
    60% identity, 91% coverage of query (638 bits)

treA / P39795 trehalose-6-phosphate hydrolase (EC 3.2.1.93) from Bacillus subtilis (strain 168) (see paper)
TREC_BACSU / P39795 Trehalose-6-phosphate hydrolase; Alpha,alpha-phosphotrehalase; Phospho-alpha-(1-1)-glucosidase; EC 3.2.1.93 from Bacillus subtilis (strain 168) (see 2 papers)
CAB12610.1 trehalose-6-phosphate hydrolase (TreA;BSU07810) (EC 3.2.1.93) (see protein)
    56% identity, 98% coverage of query (632 bits)

PS417_23045 Alpha,alpha-phosphotrehalase (EC 3.2.1.93) from Pseudomonas simiae WCS417
    56% identity, 98% coverage of query (615 bits)

treA / CAA56495.1 phospho alpha (1-1) glucosidase from Bacillus subtilis (see paper)
treA / CAA91015.1 TreA from Bacillus subtilis (see 2 papers)
    58% identity, 91% coverage of query (613 bits)

AAG31032.1 trehalose-6-phosphate hydrolase (TreA) (EC 3.2.1.93) (see protein)
    56% identity, 98% coverage of query (611 bits)

AO353_15985 Alpha,alpha-phosphotrehalase (EC 3.2.1.93) from Pseudomonas fluorescens FW300-N2E3
    56% identity, 98% coverage of query (608 bits)

AAN06917.1 trehalose-6-phosphate hydrolase (TreA) (EC 3.2.1.93) (see protein)
    59% identity, 90% coverage of query (601 bits)

O16G_PARTM / P29094 Oligo-1,6-glucosidase; Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase; EC 3.2.1.10 from Parageobacillus thermoglucosidasius (Geobacillus thermoglucosidasius) (see paper)
BAA01368.1 oligo-α-1,6-glucosidase (MalL) (EC 3.2.1.10) (see protein)
    47% identity, 98% coverage of query (535 bits)

CAA37583.1 oligo-α-1,6-glucosidase (MalL) (EC 3.2.1.10) (see protein)
    45% identity, 98% coverage of query (534 bits)

AAP10934.1 oligo-α-1,6-glucosidase (BC4015) (EC 3.2.1.10) (see protein)
    45% identity, 98% coverage of query (534 bits)

O16G2_BACSU / O34364 Probable oligo-1,6-glucosidase 2; Oligosaccharide alpha-1,6-glucosidase 2; Sucrase-isomaltase 2; Isomaltase 2; EC 3.2.1.10 from Bacillus subtilis (strain 168) (see paper)
    47% identity, 99% coverage of query (529 bits)

ACE77085.1 oligosaccharide-producing multifunctional amylase (OPMA) (EC 2.4.1.-) (see protein)
    46% identity, 99% coverage of query (518 bits)

O16G1_BACSU / O06994 Oligo-1,6-glucosidase 1; Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase 1; Sucrase-isomaltase 1; Isomaltase 1; EC 3.2.1.10 from Bacillus subtilis (strain 168) (see 3 papers)
CAB15461.1 α-1,6-glucosidase (MalL;YvdL;BSU34560) (EC 3.2.1.10) (see protein)
    46% identity, 99% coverage of query (517 bits)

7lv6B / O06994 The structure of mall mutant enzyme s536r from bacillus subtilis
    46% identity, 98% coverage of query (517 bits)

ABF38825.1 MGAS10750_Spy1875 (DexS) (EC 3.2.1.93) (see protein)
    48% identity, 98% coverage of query (516 bits)

5wczA Crystal structure of wild-type mall from bacillus subtilis with ts analogue 1-deoxynojirimycin
    46% identity, 98% coverage of query (516 bits)

5do8B / Q8YAE6 1.8 angstrom crystal structure of listeria monocytogenes lmo0184 alpha-1,6-glucosidase (see paper)
    45% identity, 98% coverage of query (515 bits)

4mazA The structure of mall mutant enzyme v200s from bacillus subtilus
    46% identity, 98% coverage of query (515 bits)

BAA11354.1 oligo-α-1,6-glucosidase (MalL) (EC 3.2.1.10) (see protein)
    46% identity, 99% coverage of query (514 bits)

4m56A The structure of wild-type mall from bacillus subtilis
    46% identity, 98% coverage of query (512 bits)

D7VFY4 oligo-1,6-glucosidase (EC 3.2.1.10) from Lactiplantibacillus plantarum subsp. plantarum (see paper)
    48% identity, 92% coverage of query (510 bits)

Q5FMB7 glucan 1,6-alpha-glucosidase (EC 3.2.1.70) from Lactobacillus acidophilus (see paper)
AAV42157.1 oligo-α-1,6-glucosidase (LBA0264) (EC 3.2.1.10) (see protein)
    46% identity, 98% coverage of query (508 bits)

4aieA / Q5FMB7 Structure of glucan-1,6-alpha-glucosidase from lactobacillus acidophilus ncfm (see paper)
    46% identity, 98% coverage of query (507 bits)

Q9F4G4 oligo-1,6-glucosidase (EC 3.2.1.10) from Bacillus subtilis (see paper)
AAG23399.1 oligo-α-1,6-glucosidase (EC 3.2.1.10) (see protein)
    45% identity, 99% coverage of query (505 bits)

AAA25570.1 α-glucosidase (Agl) (EC 3.2.1.20) (see protein)
    46% identity, 98% coverage of query (498 bits)

CAA54266.1 α-glucosidase (EC 3.2.1.20) (see protein)
CAA54266.1 alpha-glucosidase from Bacillus sp. (see paper)
    47% identity, 91% coverage of query (498 bits)

AAV42863.1 LBA1014 (TreC;La1014) (EC 3.2.1.93) (see protein)
    46% identity, 97% coverage of query (491 bits)

BAA12704.1 α-glucosidase / exo-α-1,4-glucosidase (EC 3.2.1.20) (see protein)
    44% identity, 98% coverage of query (463 bits)

Q33E90 alpha-glucosidase (EC 3.2.1.20) from Geobacillus sp. HTA-462 (see paper)
BAE48285.1 α-glucosidase (Gsj) (EC 3.2.1.20) (see protein)
    43% identity, 98% coverage of query (462 bits)

BAA00534.1 oligo-α-1,6-glucosidase (EC 3.2.1.10) (see protein)
    45% identity, 90% coverage of query (459 bits)

Q99040 glucan 1,6-alpha-glucosidase (EC 3.2.1.70) from Streptococcus mutans serotype c (see paper)
    46% identity, 91% coverage of query (458 bits)

4wlcA / Q99040 Structure of dextran glucosidase with glucose (see paper)
    46% identity, 91% coverage of query (457 bits)

2zidA Crystal structure of dextran glucosidase e236q complex with isomaltotriose
    46% identity, 91% coverage of query (457 bits)

C0JP82 oligo-1,6-glucosidase (EC 3.2.1.10) from Bifidobacterium breve (see paper)
ACM89182.1 α-1,6-glucosidase 1 (Agl1; Bbr_1855) (EC 3.2.1.10|3.2.1.20) (see protein)
    45% identity, 91% coverage of query (456 bits)

AAA26939.1 dextran α-1,6-glucosidase (DexB) (EC 3.2.1.70) (see protein)
    45% identity, 91% coverage of query (454 bits)

BAE79634.1 dextran α-1,6-glucosidase (DexB;SmDG) (EC 3.2.1.70) (see protein)
    46% identity, 91% coverage of query (451 bits)

Q6XNK5 isomaltulose synthase (EC 5.4.99.11) from Erwinia rhapontici (see paper)
    43% identity, 92% coverage of query (449 bits)

palQ / Q9AI62 palatinase (EC 3.2.1.219) from Erwinia rhapontici (see paper)
AAK28737.1 oligo-α-glucosidase / palatinase (PalQ) (EC 3.2.1.10|3.2.1.-) (see protein)
    43% identity, 99% coverage of query (447 bits)

D9MPF2 isomaltulose synthase (EC 5.4.99.11) from Erwinia rhapontici (see 3 papers)
    43% identity, 92% coverage of query (447 bits)

palI / Q9AI64 isomaltulose synthase (EC 5.4.99.11) from Erwinia rhapontici (see 2 papers)
Q9AI64 isomaltulose synthase (EC 5.4.99.11) from Erwinia rhapontici (see paper)
    43% identity, 92% coverage of query (447 bits)

4howA / D9MPF2 The crystal structure of isomaltulose synthase from erwinia rhapontici nx5 (see paper)
    43% identity, 92% coverage of query (446 bits)

AAK28739.1 α-glucosidase (PalZ) (EC 3.2.1.20) (see protein)
    42% identity, 98% coverage of query (446 bits)

8ibkA / A0A2Z5WH92 Crystal structure of bacillus sp. Ahu2216 gh13_31 alpha-glucosidase e256q/n258g in complex with maltotriose (see paper)
    41% identity, 99% coverage of query (446 bits)

4hphA The crystal structure of isomaltulose synthase mutant e295q from erwinia rhapontici nx5 in complex with its natural substrate sucrose
    43% identity, 92% coverage of query (446 bits)

4hozA The crystal structure of isomaltulose synthase mutant d241a from erwinia rhapontici nx5 in complex with d-glucose
    43% identity, 92% coverage of query (444 bits)

C1DMP8 isomaltulose synthase (EC 5.4.99.11) from Azotobacter vinelandii (see paper)
    41% identity, 98% coverage of query (443 bits)

S5YEW8 isomaltulose synthase (EC 5.4.99.11) from Pectobacterium carotovorum (see paper)
    40% identity, 98% coverage of query (442 bits)

B5ABD8 isomaltulose synthase (EC 5.4.99.11) from Enterobacter sp. FMB-1 (see 3 papers)
    40% identity, 100% coverage of query (442 bits)

A0A223KY92 alpha-amylase (EC 3.2.1.1) from Sutcliffiella cohnii (see paper)
    42% identity, 98% coverage of query (441 bits)

C0JP83 oligo-1,6-glucosidase (EC 3.2.1.10) from Bifidobacterium breve (see paper)
ACM89183.1 α-1,6-glucosidase 2 (Agl2; Bbr_0559) (EC 3.2.1.10|3.2.1.20) (see protein)
    44% identity, 93% coverage of query (441 bits)

2ze0A / Q33E90 Alpha-glucosidase gsj (see paper)
    43% identity, 98% coverage of query (440 bits)

CAA02858.1 palatinase / trehalulose hydrolase (MutA) (EC 3.2.1.10|3.2.1.-) (see protein)
    44% identity, 91% coverage of query (437 bits)

Q4L2Q1 isomaltulose synthase (EC 5.4.99.11) from Klebsiella pneumoniae (see paper)
    40% identity, 99% coverage of query (434 bits)

AAK27723.1 oligo α-glucosidase (AglA) (EC 3.2.1.10) (see protein)
    42% identity, 91% coverage of query (434 bits)

Q8KR84 isomaltulose synthase (EC 5.4.99.11) from Klebsiella sp. LX3 (see paper)
    40% identity, 99% coverage of query (434 bits)

D0VX20 isomaltulose synthase (EC 5.4.99.11) from Serratia plymuthica (see 4 papers)
3gbeA / D0VX20 Crystal structure of the isomaltulose synthase smua from protaminobacter rubrum in complex with the inhibitor deoxynojirimycin (see paper)
    41% identity, 93% coverage of query (430 bits)

Q2PS28 isomaltulose synthase (EC 5.4.99.11) from Paraburkholderia acidicola (see 3 papers)
    41% identity, 91% coverage of query (421 bits)

4h8vA / M1E1F6 Crystal structure of the trehalulose synthase mutb in complex with trehalulose
    41% identity, 91% coverage of query (419 bits)

M1E1F6 isomaltulose synthase (EC 5.4.99.11) from Rhizobium sp. MX-45 (see paper)
    41% identity, 91% coverage of query (419 bits)

2pwdA Crystal structure of the trehalulose synthase mutb from pseudomonas mesoacidophila mx-45 complexed to the inhibitor deoxynojirmycin
    41% identity, 91% coverage of query (419 bits)

2pwgA Crystal structure of the trehalulose synthase mutb from pseudomonas mesoacidophila mx-45 complexed to the inhibitor castanospermine
    41% identity, 91% coverage of query (419 bits)

2pweA Crystal structure of the mutb e254q mutant in complex with the substrate sucrose
    41% identity, 91% coverage of query (418 bits)

M1E1F7 isomaltulose synthase (EC 5.4.99.11) from Rhizobium sp. (see paper)
    41% identity, 91% coverage of query (417 bits)

M1E1F3 isomaltulose synthase (EC 5.4.99.11) from Rhizobium sp. (see paper)
    41% identity, 91% coverage of query (417 bits)

2pwfA Crystal structure of the mutb d200a mutant in complex with glucose
    41% identity, 91% coverage of query (417 bits)

4ha1A Mutb inactive double mutant d200a-d415n in complex with isomaltulose
    41% identity, 91% coverage of query (415 bits)

CAA55409.1 α-1,4-glucosidase (MalA) (EC 3.2.1.20) (see protein)
    38% identity, 98% coverage of query (404 bits)

D8J7H2 alpha-amylase (EC 3.2.1.1) from Halalkalicoccus jeotgali (see paper)
    41% identity, 98% coverage of query (403 bits)

BAB59003.1 α-glucosidase / maltase (MalT;AO090038000234) (EC 3.2.1.20) (see protein)
    40% identity, 98% coverage of query (399 bits)

AAF26276.1 α-1,6-glucosidase / glucodextranase (GlcA) (EC 3.2.1.70) (see protein)
    41% identity, 92% coverage of query (389 bits)

MAL2 maltase involved in sucrose utilization from Candida albicans (see 3 papers)
    38% identity, 98% coverage of query (383 bits)

AAA34350.2 α-glucosidase (Mal2;Mal1) (EC 3.2.1.20) (see protein)
    38% identity, 98% coverage of query (383 bits)

agdF maltase MalT (AFU_orthologue; AFUA_8G07070) from Emericella nidulans (see paper)
    38% identity, 98% coverage of query (380 bits)

7p01A Structure of the maltase baag2 from blastobotrys adeninivorans in complex with acarbose (see paper)
    37% identity, 98% coverage of query (375 bits)

MALT_SCHPO / Q9P6J3 Alpha-glucosidase; Maltase; EC 3.2.1.20 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
mal1 / RF|NP_595063.1 maltase alpha-glucosidase Mal1; EC 3.2.1.20 from Schizosaccharomyces pombe (see 2 papers)
    35% identity, 98% coverage of query (368 bits)

orf19.3982 maltase from Candida albicans (see paper)
    36% identity, 99% coverage of query (366 bits)

IMA5_YEAST / P40884 Oligo-1,6-glucosidase IMA5; Alpha-glucosidase; Isomaltase 5; EC 3.2.1.10 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P40884 oligo-1,6-glucosidase (EC 3.2.1.10) from Saccharomyces cerevisiae (see paper)
CAA83995.1 α-glucosidase (Ima5;IMA5;YJL216c) (EC 3.2.1.20) (see protein)
    36% identity, 100% coverage of query (355 bits)

BAD00094.1 oligo-α-1,6-glucosidase (EC 3.2.1.10) (see protein)
    36% identity, 98% coverage of query (355 bits)

MALX3_YEAST / P53051 Oligo-1,6-glucosidase IMA1; Alpha-glucosidase; Isomaltase 1; EC 3.2.1.10 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
P53051 oligo-1,6-glucosidase (EC 3.2.1.10) from Saccharomyces cerevisiae (see 2 papers)
BAA07818.1 oligo-α-1,6-glucosidase / isomaltase (Ima1;IMA1;Fsp2;YGR287c) (EC 3.2.1.10) (see protein)
    36% identity, 98% coverage of query (354 bits)

3a47A / P53051 Crystal structure of isomaltase from saccharomyces cerevisiae
    36% identity, 98% coverage of query (353 bits)

3a4aA Crystal structure of isomaltase from saccharomyces cerevisiae
    36% identity, 98% coverage of query (353 bits)

AAF69018.1 α-glucosidase (MAL1) (EC 3.2.1.20) (see protein)
    38% identity, 93% coverage of query (348 bits)

MALX2_YEAST / P0CW40 Oligo-1,6-glucosidase IMA3; Alpha-glucosidase; Isomaltase 3; EC 3.2.1.10 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
MALX4_YEAST / P0CW41 Oligo-1,6-glucosidase IMA4; Alpha-glucosidase; Flocculent-specific protein 2; Isomaltase 4; EC 3.2.1.10 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P0CW40 oligo-1,6-glucosidase (EC 3.2.1.10) from Saccharomyces cerevisiae (see paper)
CAA83990.1 α-glucosidase (Ima4;Fsp2;YJL221C) (EC 3.2.1.20) (see protein)
CAA87020.1 α-glucosidase (Ima3;IMA3;YIL172C) (EC 3.2.1.20) (see protein)
    36% identity, 98% coverage of query (341 bits)

IMA2_YEAST / Q08295 Oligo-1,6-glucosidase IMA2; Alpha-glucosidase; Isomaltase 2; EC 3.2.1.10 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
Q08295 oligo-1,6-glucosidase (EC 3.2.1.10) from Saccharomyces cerevisiae (see paper)
CAA99179.1 α-glucosidase (Ima2;IMA2;YOL157c) (EC 3.2.1.20) (see protein)
    36% identity, 98% coverage of query (341 bits)

MAL12_YEAST / P53341 Alpha-glucosidase MAL12; Maltase; EC 3.2.1.20 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P53341 alpha-glucosidase (EC 3.2.1.20) from Saccharomyces cerevisiae (see paper)
CAA97325.1 α-glucosidase (Mal1S;Mal12;YGR292W) (EC 3.2.1.20) (see protein)
    35% identity, 99% coverage of query (330 bits)

MAL32_YEAST / P38158 Alpha-glucosidase MAL32; Maltase; EC 3.2.1.20 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
CAA85264.1 α-glucosidase (AGL;Mal3S;Mal32;YBR299W;YBR2117) (EC 3.2.1.20) (see protein)
    35% identity, 99% coverage of query (328 bits)

AAA34757.1 α-glucosidase (Mal6S;Mal62) (EC 3.2.1.20) (see protein)
    35% identity, 99% coverage of query (327 bits)

Q5SL12 alpha-glucosidase (EC 3.2.1.20) from Thermus thermophilus HB8 (see paper)
BAD70304.1 α-glucosidase (TTHA0481) (EC 3.2.1.20) (see protein)
    39% identity, 91% coverage of query (324 bits)

AAS80455.1 α,α-trehalase / α-glucosidase (TTC0107) (EC 3.2.1.20|3.2.1.28) (see protein)
    39% identity, 91% coverage of query (324 bits)

AAD50603.1 α-glucosidase (EC 3.2.1.20) (see protein)
    39% identity, 91% coverage of query (323 bits)

BAB18518.1 oligo-α-1,6-glucosidase (EC 3.2.1.10) (see protein)
    39% identity, 91% coverage of query (323 bits)

AKA95141.1 α-glucosidase (TtAG) (EC 3.2.1.20) (see protein)
    39% identity, 91% coverage of query (322 bits)

CAB46746.1 α-glucosidase (maltase mal22) (EC 3.2.1.20) (see protein)
    36% identity, 98% coverage of query (322 bits)

6y9tA / Q5FI02 Family gh13_31 enzyme (see paper)
    35% identity, 92% coverage of query (315 bits)

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Build an alignment for 18264 and 99 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory