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Searching for up to 100 curated homologs for 18294 FitnessBrowser__Keio:18294 (339 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

Removed hits that are identical to the query, leaving 98

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

7bu2B / P27250 Structure of alcohol dehydrogenase yjgb from escherichia coli (see paper)
    100% identity, 99% coverage of query (697 bits)

W6CX26 alcohol dehydrogenase (EC 1.1.1.1); aryl-alcohol dehydrogenase (EC 1.1.1.90); aryl-alcohol dehydrogenase (NADP+) (EC 1.1.1.91) from Yokenella sp. (see paper)
    91% identity, 100% coverage of query (620 bits)

6c49A / A0A1E3MC83 Crystal structure of alcohol dehydrogenase from acinetobacter baumannii
    61% identity, 100% coverage of query (397 bits)

alrA / BAB12270.1 NADP-dependent alcohol dehydrogenase from Acinetobacter sp. M-1 (see paper)
    58% identity, 99% coverage of query (368 bits)

ADHA_SYNY3 / P74721 Aldehyde reductase AdhA; Alcohol dehydrogenase AdhA; EC 1.1.1.2 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 3 papers)
P74721 alcohol dehydrogenase (EC 1.1.1.1) from Synechocystis sp. PCC 6803 (see paper)
    49% identity, 99% coverage of query (344 bits)

A1R6C3 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Paenarthrobacter aurescens (see paper)
    39% identity, 99% coverage of query (256 bits)

adhA / C0SPA5 S-(hydroxymethyl)bacillithiol dehydrogenase (EC 1.1.1.306) from Bacillus subtilis (strain 168) (see 2 papers)
ADHA_BACSU / C0SPA5 Probable formaldehyde dehydrogenase AdhA; EC 1.1.1.- from Bacillus subtilis (strain 168) (see paper)
    37% identity, 91% coverage of query (236 bits)

A0A125SUY5 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Mycobacterium sp. (see paper)
    36% identity, 99% coverage of query (229 bits)

P9WQC5 NADP-dependent alcohol dehydrogenase C; EC 1.1.1.2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
    37% identity, 99% coverage of query (229 bits)

ADHC1_MYCS2 / P0CH36 NADP-dependent alcohol dehydrogenase C 1; Ms-ADHC 1; EC 1.1.1.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see 2 papers)
ADHC2_MYCS2 / P0CH37 NADP-dependent alcohol dehydrogenase C 2; Ms-ADHC 2; EC 1.1.1.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see 2 papers)
    36% identity, 99% coverage of query (223 bits)

T1WW77 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    38% identity, 97% coverage of query (219 bits)

T1WUU2 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    36% identity, 97% coverage of query (213 bits)

SAD / Q94G59 sinapyl alcohol dehydrogenase (EC 1.1.1.195) from Populus tremuloides (see paper)
    36% identity, 97% coverage of query (212 bits)

1yqdA / Q94G59 Sinapyl alcohol dehydrogenase complexed with NADP+ (see paper)
    36% identity, 97% coverage of query (211 bits)

T1WWB9 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    37% identity, 97% coverage of query (211 bits)

K9S0X0 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Perilla frutescens var. hirtella (see paper)
    35% identity, 98% coverage of query (210 bits)

A0A023RBJ1 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    37% identity, 97% coverage of query (210 bits)

K9RZL7 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Perilla frutescens var. hirtella (see paper)
    35% identity, 98% coverage of query (209 bits)

T1WVG5 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    36% identity, 98% coverage of query (208 bits)

10HGO / Q6V4H0 8-hydroxygeraniol dehydrogenase (EC 1.1.1.324) from Catharanthus roseus (see paper)
10HGO_CATRO / Q6V4H0 8-hydroxygeraniol dehydrogenase; Cr10HGO; EC 1.1.1.324 from Catharanthus roseus (Madagascar periwinkle) (Vinca rosea)
    39% identity, 97% coverage of query (208 bits)

T1WWR8 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    37% identity, 97% coverage of query (208 bits)

6k3gB / Q6V4H0 Crystal structure of 10-hydroxygeraniol dehydrogenase from cantharanthus roseus in complex with NADP+ (see paper)
    39% identity, 97% coverage of query (208 bits)

K9S1J6 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Perilla frutescens (see paper)
    35% identity, 98% coverage of query (207 bits)

GEDH1 / Q2KNL6 geraniol dehydrogenase (EC 1.1.1.183) from Ocimum basilicum (see paper)
GEDH1_OCIBA / Q2KNL6 Geraniol dehydrogenase 1; ObaGEDH1; EC 1.1.1.183 from Ocimum basilicum (Sweet basil) (see paper)
Q2KNL6 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Ocimum basilicum (see paper)
    35% identity, 98% coverage of query (205 bits)

MTD / Q38707 mannitol dehydrogenase (EC 1.1.1.255) from Apium graveolens (see paper)
Q38707 mannitol dehydrogenase (EC 1.1.1.255) from Apium graveolens (see paper)
    34% identity, 97% coverage of query (205 bits)

CADH2_ARATH / Q9SJ25 Cinnamyl alcohol dehydrogenase 2; AtCAD2; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    35% identity, 97% coverage of query (204 bits)

Q9ATW1 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Fragaria x ananassa (see paper)
    37% identity, 97% coverage of query (204 bits)

T1WUT6 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    35% identity, 97% coverage of query (203 bits)

Q7XWU3 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Oryza sativa Japonica Group (see paper)
    35% identity, 98% coverage of query (203 bits)

CADH3_ARATH / Q9SJ10 Cinnamyl alcohol dehydrogenase 3; AtCAD3; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    35% identity, 97% coverage of query (202 bits)

CAD7 / Q02971 cinnamyl alcohol dehydrogenase 7 (EC 1.1.1.195) from Arabidopsis thaliana (see 2 papers)
CADH7_ARATH / Q02971 Cinnamyl alcohol dehydrogenase 7; AtCAD7; Cinnamyl alcohol dehydrogenase-like protein B; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    36% identity, 97% coverage of query (202 bits)

CADH9_ARATH / P42734 Probable cinnamyl alcohol dehydrogenase 9; AtCAD9; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    34% identity, 97% coverage of query (199 bits)

B5AR58 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Leucaena leucocephala (see paper)
    36% identity, 97% coverage of query (196 bits)

CADH6_ARATH / O65621 Probable cinnamyl alcohol dehydrogenase 6; AtCAD6; Cinnamyl alcohol dehydrogenase-like protein A; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    34% identity, 97% coverage of query (195 bits)

F6L7F5 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Camellia sinensis (see paper)
    35% identity, 97% coverage of query (195 bits)

CADH8_ARATH / Q02972 Cinnamyl alcohol dehydrogenase 8; AtCAD8; NAD-dependent mannitol dehydrogenase 2; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    35% identity, 97% coverage of query (194 bits)

Q1HGA8 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Linum usitatissimum (see 3 papers)
    33% identity, 98% coverage of query (192 bits)

5vktA / C5XC49 Cinnamyl alcohol dehydrogenases (sbcad4) from sorghum bicolor (l.) Moench (see paper)
    35% identity, 97% coverage of query (192 bits)

C5XC49 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Sorghum bicolor (see 2 papers)
    35% identity, 97% coverage of query (192 bits)

YahK / b0325 aldehyde reductase, NADPH-dependent (EC 1.1.1.2; EC 1.1.1.55) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
yahK / P75691 aldehyde reductase, NADPH-dependent (EC 1.1.1.2; EC 1.1.1.55) from Escherichia coli (strain K12) (see 7 papers)
YAHK_ECOLI / P75691 Aldehyde reductase YahK; Zinc-dependent alcohol dehydrogenase YahK; EC 1.1.1.2 from Escherichia coli (strain K12) (see 2 papers)
yahK / MB|P75691 zinc-type alcohol dehydrogenase-like protein yahK from Escherichia coli K12 (see paper)
    35% identity, 99% coverage of query (190 bits)

T3R_CATRO / A0A161CAI1 16-methoxy-2,3-dihydro-3-hydroxytabersonine synthase; 3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine reductase; Alcohol dehydrogenase-like protein 1; ADHL1; Tabersonine 3-reductase; EC 1.1.99.41 from Catharanthus roseus (Madagascar periwinkle) (Vinca rosea) (see 2 papers)
A0A161CAI1 3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine reductase (EC 1.1.99.41) from Catharanthus roseus (see 2 papers)
    32% identity, 97% coverage of query (190 bits)

B5TR18 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Leucaena leucocephala (see paper)
    35% identity, 97% coverage of query (188 bits)

5z0cA / J7JYU1 Nerol dehydrogenase from persicaria minor (see paper)
    35% identity, 97% coverage of query (188 bits)

CAD1_MEDTR / A0A072VPZ8 Cinnamyl alcohol dehydrogenase 1; Mt-CAD1; Coniferol dehydrogenase; Coumaroyl alcohol dehydrogenase; Sinapyl alcohol dehydrogenase; EC 1.1.1.195 from Medicago truncatula (Barrel medic) (Medicago tribuloides) (see paper)
    34% identity, 97% coverage of query (187 bits)

cad / O25732 cinnamyl-alcohol dehydrogenase (EC 1.1.1.2; EC 1.1.1.95; EC 1.1.1.195) from Helicobacter pylori (strain ATCC 700392 / 26695) (see 3 papers)
    32% identity, 98% coverage of query (186 bits)

6iqdA / P42327 Crystal structure of alcohol dehydrogenase from geobacillus stearothermophilus (see paper)
    31% identity, 98% coverage of query (186 bits)

Q8H0L8 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Solanum tuberosum (see paper)
    35% identity, 97% coverage of query (186 bits)

P12311 Alcohol dehydrogenase; ADH-T; EC 1.1.1.1 from Geobacillus stearothermophilus (Bacillus stearothermophilus)
    33% identity, 95% coverage of query (185 bits)

1uufA / P75691 Crystal structure of a zinc-type alcohol dehydrogenase-like protein yahk
    34% identity, 99% coverage of query (182 bits)

8a3nB / W8JWW7 Geissoschizine synthase from catharanthus roseus - binary complex with NADP+ (see paper)
    33% identity, 97% coverage of query (182 bits)

A0A1D6BJ11 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Triticum aestivum (see paper)
    34% identity, 97% coverage of query (182 bits)

CADH7_ORYSJ / Q0JA75 Cinnamyl alcohol dehydrogenase 7; OsCAD7; Protein FLEXIBLE CULM 1; EC 1.1.1.195 from Oryza sativa subsp. japonica (Rice) (see paper)
    35% identity, 97% coverage of query (181 bits)

GS1 / W8JWW7 geissoschizine synthase (EC 1.3.1.36) from Catharanthus roseus (see 2 papers)
GS_CATRO / W8JWW7 Geissoschizine synthase; CrGS; Alcohol dehydrogenase 14; CrADH14; EC 1.3.1.36 from Catharanthus roseus (Madagascar periwinkle) (Vinca rosea) (see 4 papers)
    32% identity, 97% coverage of query (180 bits)

CADH1_ARATH / Q9CAI3 Probable cinnamyl alcohol dehydrogenase 1; AtCAD1; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    33% identity, 97% coverage of query (180 bits)

D0ITF8 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Helicobacter pylori (see paper)
3twoB / D0ITF8 The crystal structure of cad from helicobacter pylori complexed with NADP(h) (see paper)
    31% identity, 98% coverage of query (179 bits)

P42328 alcohol dehydrogenase (EC 1.1.1.1) from Geobacillus stearothermophilus (see 8 papers)
1rjwA / P42328 Crystal structure of NAD(+)-dependent alcohol dehydrogenase from bacillus stearothermophilus strain lld-r (see paper)
    33% identity, 94% coverage of query (179 bits)

5fi3A / A0A0F6SD02 Heteroyohimbine synthase thas1 from catharanthus roseus - complex with NADP+ (see paper)
    32% identity, 97% coverage of query (179 bits)

Q6RS93 alcohol dehydrogenase (EC 1.1.1.1) from Parageobacillus thermoglucosidasius (see paper)
    32% identity, 94% coverage of query (177 bits)

G3DSC5 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Liriodendron tulipifera (see paper)
    30% identity, 99% coverage of query (177 bits)

3piiA Crystal structure of mutant of ht- alcohol dehydrogenase with substrate analogue butyramide
    32% identity, 94% coverage of query (177 bits)

Redox1 / A0A2P1GIW4 Redox 1 from Catharanthus roseus (see paper)
REDX1_CATRO / A0A2P1GIW4 Protein REDOX 1; Cinnamyl alcohol dehydrogenase 4; EC 1.14.14.- from Catharanthus roseus (Madagascar periwinkle) (Vinca rosea) (see 2 papers)
    32% identity, 97% coverage of query (176 bits)

7cguA / A0A8A5L0G9 Crystal structure of abhar
    33% identity, 98% coverage of query (176 bits)

CAD1 / Q2KNL5 geraniol dehydrogenase (EC 1.1.1.183) from Ocimum basilicum (see paper)
CADH1_OCIBA / Q2KNL5 Cinnamyl alcohol dehydrogenase 1; CAD 1; ObaCAD1; EC 1.1.1.195 from Ocimum basilicum (Sweet basil) (see paper)
    36% identity, 97% coverage of query (176 bits)

5h83A / A0A1C7D195 Heteroyohimbine synthase hys from catharanthus roseus - apo form (see paper)
    32% identity, 97% coverage of query (174 bits)

A3GHR6 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Scheffersomyces stipitis (see paper)
    33% identity, 94% coverage of query (174 bits)

CAD4 / P48523 cinnamyl alcohol dehydrogenase 4 (EC 1.1.1.195) from Arabidopsis thaliana (see paper)
CADH4_ARATH / P48523 Cinnamyl alcohol dehydrogenase 4; AtCAD4; Cinnamyl alcohol dehydrogenase C; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
P48523 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Arabidopsis thaliana (see 3 papers)
    34% identity, 97% coverage of query (170 bits)

CAD1_CAPAN / B5LAT8 Cinnamyl alcohol dehydrogenase 1; CaCAD1; Vanillyl alcohol synthase; EC 1.1.1.195; EC 1.1.1.- from Capsicum annuum (Capsicum pepper) (see paper)
    34% identity, 97% coverage of query (170 bits)

8b25B / A0A5B8X8Z0 Dihydroprecondylocarpine acetate synthase 2 from tabernanthe iboga - stemmadenine acetate bound structure (see paper)
    32% identity, 91% coverage of query (168 bits)

8b1vA Dihydroprecondylocarpine acetate synthase 2 from tabernanthe iboga
    32% identity, 91% coverage of query (168 bits)

F6L7F4 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Camellia sinensis (see paper)
    35% identity, 97% coverage of query (167 bits)

7c2oA / M4VRJ6 Crystal structure of the r-specific carbonyl reductase from candida parapsilosis atcc 7330 without dtt
    34% identity, 94% coverage of query (164 bits)

M4VRJ6 carbonyl reductase (NADPH) (EC 1.1.1.184) from Candida parapsilosis (see paper)
    34% identity, 94% coverage of query (164 bits)

NOTN_ASPSM / E1ACQ9 Alcohol dehydrogenase notN; Notoamide biosynthesis cluster protein N; EC 1.1.1.1 from Aspergillus sp. (strain MF297-2) (see 3 papers)
    32% identity, 100% coverage of query (162 bits)

3s2eA / Q46UZ9 Crystal structure of furx nadh complex 1
    31% identity, 100% coverage of query (162 bits)

3s2fE Crystal structure of furx nadh:furfural
    31% identity, 100% coverage of query (162 bits)

3s2fA Crystal structure of furx nadh:furfural
    31% identity, 100% coverage of query (162 bits)

3s2eE Crystal structure of furx nadh complex 1
    31% identity, 100% coverage of query (162 bits)

furX / Q46UZ9 furfuryl alcohol dehydrogenase (EC 1.1.1.1) from Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (see paper)
    31% identity, 100% coverage of query (161 bits)

DPAS / A0A1B1FHP3 dehydroprecondylocarpine acetate synthase from Catharanthus roseus (see 2 papers)
DPAS_CATRO / A0A1B1FHP3 Dehydroprecondylocarpine acetate synthase; EC 1.1.1.- from Catharanthus roseus (Madagascar periwinkle) (Vinca rosea) (see paper)
    33% identity, 91% coverage of query (161 bits)

T1WW82 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    35% identity, 98% coverage of query (161 bits)

Q8L3C9 alcohol dehydrogenase (EC 1.1.1.1) from Flavobacterium frigidimaris (see paper)
    30% identity, 98% coverage of query (159 bits)

ADH6_YEAST / Q04894 NADP-dependent alcohol dehydrogenase 6; NADP-dependent alcohol dehydrogenase VI; ScADHVI; EC 1.1.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 6 papers)
1piwA / Q04894 Apo and holo structures of an NADP(h)-dependent cinnamyl alcohol dehydrogenase from saccharomyces cerevisiae (see paper)
    32% identity, 93% coverage of query (157 bits)

YL498_MIMIV / Q5UQG2 Probable zinc-type alcohol dehydrogenase-like protein L498; EC 1.-.-.- from Acanthamoeba polyphaga mimivirus (APMV) (see paper)
    30% identity, 97% coverage of query (157 bits)

Build an alignment

Build an alignment for 18294 and 83 homologs with ≥ 30% identity

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Change minimum %identity:

Additional hits (identity < 30%)

5h81B / A0A1C7D193 Heteroyohimbine synthase thas2 from catharanthus roseus - complex with NADP+ (see paper)
    29% identity, 97% coverage of query (156 bits)

RR42_RS34260 Alcohol dehydrogenase (EC 1.1.1.1) from Cupriavidus basilensis FW507-4G11
    30% identity, 100% coverage of query (155 bits)

A0A2Z5D8A5 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Artemisia annua (see paper)
    33% identity, 98% coverage of query (155 bits)

ADH7_YEAST / P25377 NADP-dependent alcohol dehydrogenase 7; NADP-dependent alcohol dehydrogenase VII; ADHVII; EC 1.1.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
    33% identity, 94% coverage of query (155 bits)

RR4 / A0A0U3S9Q3 vomilenine 19,20-reductase from Rauvolfia serpentina (see paper)
    30% identity, 98% coverage of query (155 bits)

1lluA / Q9HTD9 The ternary complex of pseudomonas aeruginosa alcohol dehydrogenase with its coenzyme and weak substrate (see paper)
    30% identity, 98% coverage of query (154 bits)

D7PGW0 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Triticum aestivum (see paper)
    32% identity, 99% coverage of query (153 bits)

CH_124303 alcohol dehydrogenase 1 from Magnaporthe grisea 70-15 (see paper)
    31% identity, 99% coverage of query (153 bits)

3meqA / A0A0H3G9R2 Crystal structure of alcohol dehydrogenase from brucella melitensis
    31% identity, 98% coverage of query (153 bits)

6n7lC / A0A077EGR8 Crystal structure of an alcohol dehydrogenase from elizabethkingia anophelis nuhp1
    31% identity, 98% coverage of query (153 bits)

A3GHL4 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Scheffersomyces stipitis (see paper)
    31% identity, 97% coverage of query (152 bits)

ADH_MORSE / Q8GIX7 Alcohol dehydrogenase; ADH; EC 1.1.1.1 from Moraxella sp. (strain TAE123) (see 3 papers)
Q8GIX7 alcohol dehydrogenase (EC 1.1.1.1) from Moraxella sp. (see paper)
    30% identity, 98% coverage of query (152 bits)

4z6kA / Q8GIX7 Alcohol dehydrogenase from the antarctic psychrophile moraxella sp. Tae 123
    30% identity, 98% coverage of query (152 bits)

adhA / Q8NLX9 Zn2+-dependent alcohol dehydrogenase (EC 1.1.1.1; EC 1.1.1.244) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 5 papers)
    28% identity, 96% coverage of query (148 bits)

A1ILL4 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Sorghum bicolor (see 2 papers)
    34% identity, 97% coverage of query (147 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory