Sites on a Tree

 

Searching for up to 100 curated homologs for 18314 FitnessBrowser__Keio:18314 (300 a.a.)

Found high-coverage hits (≥70%) to 36 curated proteins.

Removed hits that are identical to the query, leaving 35

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.14.8 / Q8GRB3 PvuB, component of The iron-vibrioferrin uptake porter from Vibrio parahaemolyticus (see paper)
    50% identity, 94% coverage of query (281 bits)

YFMC_BACSU / O34348 Fe(3+)-citrate-binding protein YfmC; Ferric-citrate-binding protein from Bacillus subtilis (strain 168) (see paper)
    38% identity, 90% coverage of query (209 bits)

3lhsA / A0A0H3K9U6 Open conformation of htsa complexed with staphyloferrin a (see paper)
    37% identity, 89% coverage of query (186 bits)

3li2A Closed conformation of htsa complexed with staphyloferrin a
    37% identity, 89% coverage of query (186 bits)

YHFQ_BACSU / C0SP94 Putative ABC transporter substrate-binding lipoprotein YhfQ from Bacillus subtilis (strain 168) (see 3 papers)
    32% identity, 90% coverage of query (153 bits)

Build an alignment

Build an alignment for 18314 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

3tnyA Structure of yfiy from bacillus cereus bound to the siderophore iron (iii) schizokinen
    25% identity, 90% coverage of query (91.7 bits)

FPUA_BACAN / Q81L65 Petrobactin-binding protein FpuA; Petrobactin receptor from Bacillus anthracis (see 2 papers)
    29% identity, 84% coverage of query (89.4 bits)

TC 3.A.1.14.4 / Q47084 CbrA, component of Iron-chrysobactine porter from Erwinia chrysanthemi (see paper)
    28% identity, 85% coverage of query (86.7 bits)

YFIY_BACSU / O31567 Probable siderophore-binding lipoprotein YfiY from Bacillus subtilis (strain 168) (see 3 papers)
    25% identity, 85% coverage of query (80.1 bits)

2chuA Ceue in complex with mecam
    25% identity, 84% coverage of query (72.0 bits)

5a5vA A complex of the synthetic siderophore analogue fe(iii)-6-licam with the ceue periplasmic protein from campylobacter jejuni
    24% identity, 84% coverage of query (72.0 bits)

3mwfA / A0A0H3JJC6 Crystal structure of staphylococcus aureus sira complexed with staphyloferrin b
    22% identity, 86% coverage of query (71.2 bits)

5ad1A / Q0P8Q4 A complex of the synthetic siderophore analogue fe(iii)-8-licam with the ceue periplasmic protein from campylobacter jejuni (see paper)
    25% identity, 84% coverage of query (71.2 bits)

5a5dA A complex of the synthetic siderophore analogue fe(iii)-5-licam with the ceue periplasmic protein from campylobacter jejuni
    25% identity, 84% coverage of query (71.2 bits)

5advB The periplasmic binding protein ceue of campylobacter jejuni preferentially binds the iron(iii) complex of the linear dimer component of enterobactin
    25% identity, 84% coverage of query (71.2 bits)

5advA The periplasmic binding protein ceue of campylobacter jejuni preferentially binds the iron(iii) complex of the linear dimer component of enterobactin
    25% identity, 84% coverage of query (71.2 bits)

5od5A Periplasmic binding protein ceue complexed with a synthetic catalyst
    25% identity, 84% coverage of query (71.2 bits)

5oahA The periplasmic binding protein ceue of campylobacter jejuni binds the iron(iii) complex of azotochelin
    25% identity, 84% coverage of query (71.2 bits)

5a1jA Periplasmic binding protein ceue in complex with ferric 4-licam
    25% identity, 84% coverage of query (71.2 bits)

YCLQ_BACSU / P94421 Petrobactin-binding protein YclQ from Bacillus subtilis (strain 168) (see 3 papers)
    25% identity, 82% coverage of query (68.2 bits)

3gfvB / P94421 Crystal structure of petrobactin-binding protein yclq from bacillu subtilis (see paper)
    25% identity, 82% coverage of query (68.2 bits)

TC 3.A.1.14.2 / C8U2V6 Ferric enterobactin (Enterochelin) binding protein FepB, component of Iron (Fe3+)-enterobactin porter from Escherichia coli O103:H2 (strain 12009 / EHEC) (see paper)
    25% identity, 83% coverage of query (67.8 bits)

FepB / b0592 ferric enterobactin ABC transporter periplasmic binding protein (EC 7.2.2.17) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
FepB / P0AEL6 ferric enterobactin ABC transporter periplasmic binding protein (EC 7.2.2.17) from Escherichia coli (strain K12) (see 5 papers)
FEPB_ECOLI / P0AEL6 Ferric enterobactin-binding periplasmic protein FepB from Escherichia coli (strain K12) (see 7 papers)
    25% identity, 83% coverage of query (67.4 bits)

3tlkA / P0AEL6 Crystal structure of holo fepb
    26% identity, 83% coverage of query (67.4 bits)

TC 3.A.1.14.12 / Q9L178 DesA, component of Desferrioxamine B uptake porter, DesABC from Streptomyces coelicolor (see paper)
    23% identity, 84% coverage of query (65.1 bits)

8bawA X-ray structure of the ceue homologue from geobacillus stearothermophilus - 5-licam siderophore analogue complex.
    24% identity, 83% coverage of query (65.1 bits)

8b7xA X-ray structure of the ceue homologue from geobacillus stearothermophilus - apo form.
    24% identity, 83% coverage of query (65.1 bits)

8baxA / A0A857MR34 X-ray structure of the ceue homologue from geobacillus stearothermophilus - azotochelin complex. (see paper)
    24% identity, 83% coverage of query (64.7 bits)

VATD_VIBVL / Q845T3 Ferric aerobactin-binding protein VatD; Iron(3+)-hydroxamate-binding protein VatD; Periplasmic-binding protein VatD; PBP VatD; Vulnificus aerobactin transport protein D from Vibrio vulnificus (see 3 papers)
    24% identity, 89% coverage of query (61.2 bits)

7w8fA / Q845T3 Crystal structure of siderophore binding protein vatd from vibrio vulnificus m2799 complexed with desferal
    24% identity, 87% coverage of query (57.8 bits)

5jj5A / A0A062WLD9 Crystal structure of iron uptake abc transporter substrate-binding protein piaa from streptococcus pneumoniae canada mdr_19a bound to hydroxymate siderophore ferrioxamine e and iron(iii)
    24% identity, 86% coverage of query (55.5 bits)

4hmqA Crystal structure of streptococcus pneumoniae tigr4 piaa in complex with ferrichrome
    24% identity, 86% coverage of query (55.5 bits)

5ggxD / A0A0H3AJ03 Crystal structure of fe3+ - desferal bound siderophore binding protein fhud from vibrio cholerae
    27% identity, 76% coverage of query (55.1 bits)

7sf6A / Q24WN9 Crystal structure of siderophore binding protein fatb from desulfitobacterium hafniense
    24% identity, 83% coverage of query (46.6 bits)

FATB_VIBA7 / P11460 Ferric-anguibactin-binding protein FatB from Vibrio anguillarum (strain ATCC 68554 / 775) (Listonella anguillarum) (see 2 papers)
    23% identity, 92% coverage of query (44.3 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory