Searching for up to 100 curated homologs for 18403 FitnessBrowser__Keio:18403 (440 a.a.)
Found high-coverage hits (≥70%) to 27 curated proteins.
Removed hits that are identical to the query, leaving 26
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
4lhmA Thymidine phosphorylase from e.Coli with 3'-azido-3'-deoxythymidine
100% identity, 100% coverage of query (895 bits)
4eadA Thymidine phosphorylase from e.Coli with 3'-azido-2'-fluoro- dideoxyuridine
100% identity, 100% coverage of query (895 bits)
5ey3A / Q7CP66 X-ray structure of the thymidine phosphorylase from salmonella typhimurium in complex with cytidine and sulphate
95% identity, 100% coverage of query (843 bits)
Q7CP66 thymidine phosphorylase (EC 2.4.2.4) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
95% identity, 100% coverage of query (843 bits)
4yyyB X-ray structure of the thymidine phosphorylase from salmonella typhimurium in complex with uridine
95% identity, 100% coverage of query (843 bits)
4yekA X-ray structure of the thymidine phosphorylase from salmonella typhimurium in complex with thymidine
95% identity, 100% coverage of query (843 bits)
A0A0D1XZI7 pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) from Aneurinibacillus migulanus (see paper)
45% identity, 98% coverage of query (343 bits)
A0A0E2M090 pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) from Lacticaseibacillus paracasei (see paper)
44% identity, 98% coverage of query (338 bits)
5olnB / P39142 X-ray structure of the complex pyrimidine-nucleoside phosphorylase from bacillus subtilis at 1.88 a (see paper)
46% identity, 93% coverage of query (332 bits)
PDP_BACSU / P39142 Pyrimidine-nucleoside phosphorylase; PYNP; Py-NPase; EC 2.4.2.2 from Bacillus subtilis (strain 168) (see paper)
pdp / GB|CAB15976.2 pyrimidine-nucleoside phosphorylase; EC 2.4.2.2 from Bacillus subtilis (see paper)
46% identity, 93% coverage of query (332 bits)
A0A178U4P5 pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) from Parageobacillus thermoglucosidasius (see paper)
44% identity, 99% coverage of query (330 bits)
1brwA / P77836 The crystal structure of pyrimidine nucleoside phosphorylase in a closed conformation (see paper)
43% identity, 98% coverage of query (330 bits)
7m7kB Crystal structure of uridine bound to geobacillus thermoglucosidasius pyrimidine nucleoside phosphorylase pynp
44% identity, 99% coverage of query (330 bits)
1brwB The crystal structure of pyrimidine nucleoside phosphorylase in a closed conformation
43% identity, 98% coverage of query (330 bits)
pdp / P77836 pyrimidine-nucleoside phosphorylase monomer (EC 2.4.2.3; EC 2.4.2.2) from Geobacillus stearothermophilus (see 4 papers)
PDP_GEOSE / P77836 Pyrimidine-nucleoside phosphorylase; PYNP; Py-NPase; EC 2.4.2.2 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see 2 papers)
P77836 pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) from Geobacillus stearothermophilus (see 2 papers)
pyn / GB|BAA13512.1 pyrimidine-nucleoside phosphorylase; EC 2.4.2.2 from Geobacillus stearothermophilus (see paper)
pyn / BAA13512.1 pyrimidine nucleoside phosphorylase from Geobacillus stearothermophilus (see paper)
42% identity, 99% coverage of query (322 bits)
2j0fA / P19971 Structural basis for non-competitive product inhibition in human thymidine phosphorylase: implication for drug design (see paper)
40% identity, 98% coverage of query (283 bits)
2wk6A Structural features of native human thymidine phosphorylase and in complex with 5-iodouracil
39% identity, 98% coverage of query (282 bits)
TYMP / P19971 thymidine phosphorylase monomer (EC 2.4.2.3; EC 2.4.2.2) from Homo sapiens (see 13 papers)
TYPH_HUMAN / P19971 Thymidine phosphorylase; TP; Gliostatin; Platelet-derived endothelial cell growth factor; PD-ECGF; TdRPase; EC 2.4.2.4 from Homo sapiens (Human) (see 6 papers)
P19971 thymidine phosphorylase (EC 2.4.2.4) from Homo sapiens (see 30 papers)
39% identity, 98% coverage of query (281 bits)
Q99N42 thymidine phosphorylase (EC 2.4.2.4) from Mus musculus (see 2 papers)
39% identity, 98% coverage of query (277 bits)
Q72HS4 pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) from Thermus thermophilus (see paper)
41% identity, 96% coverage of query (277 bits)
Q5SHF9 pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) from Thermus thermophilus (see paper)
41% identity, 96% coverage of query (276 bits)
1uouA Crystal structure of human thymidine phosphorylase in complex with a small molecule inhibitor
40% identity, 98% coverage of query (263 bits)
P75052 thymidine phosphorylase (EC 2.4.2.4) from Mycoplasma pneumoniae (see paper)
36% identity, 85% coverage of query (214 bits)
Build an alignment for 18403 and 23 homologs with ≥ 30% identity
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4ga6A / Q5JCX3 Crystal structure of amp phosphorylasE C-terminal deletion mutant in complex with substrates (see paper)
28% identity, 92% coverage of query (117 bits)
deoA / Q5JCX3 AMP phosphorylase (EC 2.4.2.57) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (see 2 papers)
AMPPA_THEKO / Q5JCX3 AMP phosphorylase; AMPpase; Nucleoside monophosphate phosphorylase; NMP phosphorylase; EC 2.4.2.57 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see 3 papers)
Q5JCX3 AMP phosphorylase (EC 2.4.2.57) from Thermococcus kodakarensis (see 3 papers)
28% identity, 92% coverage of query (117 bits)
4ga4A Crystal structure of amp phosphorylase n-terminal deletion mutant
28% identity, 92% coverage of query (117 bits)
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Lawrence Berkeley National Laboratory