Searching for up to 100 curated homologs for 18405 FitnessBrowser__Keio:18405 (239 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
Removed hits that are identical to the query, leaving 86
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
1ovgA M64v pnp +mepdr
100% identity, 99% coverage of query (482 bits)
1ov6A M64v pnp + allo
100% identity, 99% coverage of query (482 bits)
1oumA M64v pnp +talo
100% identity, 99% coverage of query (482 bits)
DEOD_SALTY / Q8ZJV7 Purine nucleoside phosphorylase DeoD-type; PNP; EC 2.4.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
97% identity, 100% coverage of query (472 bits)
1pr6A Escherichia coli purine nucleoside phosphorylase complexed with 9- beta-d-xylofuranosyladenine and phosphate/sulfate
99% identity, 99% coverage of query (471 bits)
1pr4A Escherichia coli purine nucleoside phosphorylase complexed with 9- beta-d-ribofuranosyl-6-methylthiopurine and phosphate/sulfate
98% identity, 99% coverage of query (466 bits)
1pr5A Escherichia coli purine nucleoside phosphorylase complexed with 7- deazaadenosine and phosphate/sulfate
97% identity, 99% coverage of query (463 bits)
3occF / B1JL34 Crystal structure of pnp with dadmeimmh from yersinia pseudotuberculosis
91% identity, 99% coverage of query (445 bits)
3of3A / Q9KPM0 Crystal structure of pnp with an inhibitor dadme_immh from vibrio cholerae
80% identity, 99% coverage of query (385 bits)
1vhwA Crystal structure of purine nucleoside phosphorylase with adenosine
80% identity, 99% coverage of query (384 bits)
C8CPR9 purine-nucleoside phosphorylase (EC 2.4.2.1) from Pseudoalteromonas sp. (see paper)
61% identity, 97% coverage of query (305 bits)
2iscD / A2E7Y6 Crystal structure of purine nucleoside phosphorylase from trichomonas vaginalis with dadme-imm-a (see paper)
59% identity, 97% coverage of query (286 bits)
deoD purine nucleoside phosphorylase; EC 2.4.2.1 from Bacillus anthracis (see paper)
57% identity, 96% coverage of query (283 bits)
3uawA / Q5EEL8 Crystal structure of adenosine phosphorylase from bacillus cereus complexed with adenosine (see paper)
57% identity, 96% coverage of query (283 bits)
P56463 purine-nucleoside phosphorylase (EC 2.4.2.1) from Helicobacter pylori (see paper)
6f4wA / P56463 Crystal structure of h. Pylori purine nucleoside phosphorylase in complex with formycin a (see paper)
55% identity, 96% coverage of query (280 bits)
7op9A Purine nucleoside phosphorylase(deod-type) from h. Pylori with 2,6- dichloropurine
55% identity, 96% coverage of query (280 bits)
7oozB Purine nucleoside phosphorylase(deod-type) from h. Pylori with 6- benzyloxo-2-chloropurine
55% identity, 96% coverage of query (280 bits)
7ooyB Purine nucleoside phosphorylase(deod-type) from h. Pylori with 6- benzylthio-2-chloropurine
55% identity, 96% coverage of query (280 bits)
5lu0A Crystal structure of h. Pylori referent strain in complex with po4
55% identity, 96% coverage of query (280 bits)
O34925 purine-nucleoside phosphorylase (EC 2.4.2.1) from Bacillus subtilis (see paper)
59% identity, 96% coverage of query (279 bits)
4daeA / O34925 Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with 6-chloroguanosine (see paper)
59% identity, 96% coverage of query (278 bits)
4da0A Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with 2'-deoxyguanosine
59% identity, 96% coverage of query (278 bits)
4darA Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with tubercidin
59% identity, 96% coverage of query (278 bits)
4dabA Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with hypoxanthine
59% identity, 96% coverage of query (278 bits)
4da8A Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with 8-bromoguanosine
59% identity, 96% coverage of query (278 bits)
4da7A Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with aciclovir
59% identity, 96% coverage of query (278 bits)
4da6A Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with ganciclovir
59% identity, 96% coverage of query (278 bits)
4d9hA Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with adenosine
59% identity, 96% coverage of query (278 bits)
4d8vA Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis at ph 4.2
59% identity, 96% coverage of query (278 bits)
A0A518Y5Z2 purine-nucleoside phosphorylase (EC 2.4.2.1) from Helicobacter pylori (see paper)
55% identity, 96% coverage of query (277 bits)
4danA Crystal structure of the hexameric purine nucleoside phosphorylase from bacillus subtilis in complex with 2-fluoroadenosine
58% identity, 95% coverage of query (276 bits)
5mx4C Crystal structure of h. Pylori purine nucleoside phosphorylase from clinical isolate hppnp-1
54% identity, 96% coverage of query (276 bits)
1z39A Crystal structure of trichomonas vaginalis purine nucleoside phosphorylase complexed with 2'-deoxyinosine
58% identity, 97% coverage of query (274 bits)
1z38A Crystal structure of trichomonas vaginalis purine nucleoside phosphorylase complexed with inosine
58% identity, 97% coverage of query (274 bits)
1z37A Crystal structure of trichomonas vaginalis purine nucleoside phosphorylase complexed with adenosine
58% identity, 97% coverage of query (274 bits)
1z36A Crystal structure of trichomonas vaginalis purine nucleoside phosphorylase complexed with formycin a
58% identity, 97% coverage of query (274 bits)
1z35A Crystal structure of trichomonas vaginalis purine nucleoside phosphorylase complexed with 2-fluoroadenosine
58% identity, 97% coverage of query (274 bits)
1z34A Crystal structure of trichomonas vaginalis purine nucleoside phosphorylase complexed with 2-fluoro-2'-deoxyadenosine
58% identity, 97% coverage of query (274 bits)
2i4tA Crystal structure of purine nucleoside phosphorylase from trichomonas vaginalis with imm-a
58% identity, 97% coverage of query (271 bits)
P77835 purine-nucleoside phosphorylase (EC 2.4.2.1) from Geobacillus stearothermophilus (see paper)
punB / BAA13510.1 purine nucleoside phosphorylase from Geobacillus stearothermophilus (see paper)
54% identity, 96% coverage of query (270 bits)
3uaxA Crystal structure of adenosine phosphorylase from bacillus cereus complexed with inosine
55% identity, 96% coverage of query (269 bits)
3u40D / C4LXG4 Crystal structure of a purine nucleoside phosphorylase from entamoeba histolytica bound to adenosine (see paper)
49% identity, 95% coverage of query (216 bits)
DEOD_MYCGE / P47295 Purine nucleoside phosphorylase DeoD-type; PNP; EC 2.4.2.1 from Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37) (Mycoplasmoides genitalium) (see paper)
45% identity, 96% coverage of query (184 bits)
Q72IR2 purine-nucleoside phosphorylase (EC 2.4.2.1) from Thermus thermophilus (see 2 papers)
35% identity, 98% coverage of query (152 bits)
1odiA / Q5SID9 Purine nucleoside phosphorylase from thermus thermophilus (see paper)
36% identity, 96% coverage of query (151 bits)
1odjA Purine nucleoside phosphorylase from thermus thermophilus
36% identity, 96% coverage of query (151 bits)
1jdtA Crystal structure of 5'-deoxy-5'-methylthioadenosine phosphorylase complexed with mta and sulfate ion
32% identity, 96% coverage of query (116 bits)
PNPH_SACS2 / P50389 Purine nucleoside phosphorylase; PNP; 5'-methylthioadenosine phosphorylase I; MTA phosphorylase I; MTAPI; EC 2.4.2.1; EC 2.4.2.28 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
P50389 S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) from Saccharolobus solfataricus (see 4 papers)
33% identity, 87% coverage of query (115 bits)
1jdvC / P50389 Crystal structure of 5'-deoxy-5'-methylthioadenosine phosphorylase complexed with adenosine and sulfate ion (see paper)
34% identity, 85% coverage of query (115 bits)
1je1A 5'-deoxy-5'-methylthioadenosine phosphorylase complex with guanosine and sulfate
34% identity, 85% coverage of query (115 bits)
1jdzA Crystal structure of 5'-deoxy-5'-methylthioadenosine phosphorylase with formycin b and sulfate ion
34% identity, 85% coverage of query (115 bits)
1jdvA Crystal structure of 5'-deoxy-5'-methylthioadenosine phosphorylase complexed with adenosine and sulfate ion
34% identity, 85% coverage of query (115 bits)
1jdsA 5'-deoxy-5'-methylthioadenosine phosphorylase complex with phosphate (space group p21)
34% identity, 85% coverage of query (115 bits)
B9LS20 guanosine phosphorylase (EC 2.4.2.15) from Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34) (see paper)
31% identity, 89% coverage of query (110 bits)
TK1479 / Q5JJC1 uridine phosphorylase (EC 2.4.2.2) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (see paper)
UDP_THEKO / Q5JJC1 Uridine phosphorylase; UPase; UrdPase; EC 2.4.2.3 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
31% identity, 95% coverage of query (108 bits)
Q5XA29 pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) from Streptococcus pyogenes (see paper)
35% identity, 80% coverage of query (100 bits)
3qpbC / Q5XA29 Crystal structure of streptococcus pyogenes uridine phosphorylase reveals a subclass of the np-i superfamily (see paper)
35% identity, 80% coverage of query (100 bits)
Q9YA34 uridine phosphorylase (EC 2.4.2.3) from Aeropyrum pernix (see 2 papers)
34% identity, 83% coverage of query (98.6 bits)
Sama_0412 Uridine phosphorylase (EC 2.4.2.3) from Shewanella amazonensis SB2B
30% identity, 83% coverage of query (93.2 bits)
Build an alignment for 18405 and 59 homologs with ≥ 30% identity
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udp / CAB94934.1 uridine phosphorylase from Yersinia pseudotuberculosis (see paper)
28% identity, 92% coverage of query (92.0 bits)
4yjkA Crystal structure of c212s mutant of shewanella oneidensis mr-1 uridine phosphorylase
30% identity, 81% coverage of query (92.0 bits)
P0A1F6 uridine phosphorylase (EC 2.4.2.3) from Salmonella enterica subsp. enterica serovar Typhimurium (see 2 papers)
2hn9A / P0A1F6 Crystal structure of the uridine phosphorylase from salmonella typhimurium in complex with thymine and phosphate ion at 2.12a resolution
28% identity, 92% coverage of query (91.7 bits)
2hwuA Crystal structure of the uridine phosphorylase from salmonella typhimurium in complex with uridine and phosphate ion at 2.91a resolution
28% identity, 92% coverage of query (91.7 bits)
BWI76_RS01295 Uridine phosphorylase (EC 2.4.2.3) from Klebsiella michiganensis M5al
27% identity, 92% coverage of query (91.3 bits)
Udp / b3831 uridine phosphorylase (EC 2.4.2.2; EC 2.4.2.3) from Escherichia coli K-12 substr. MG1655 (see 82 papers)
udp / P12758 uridine phosphorylase (EC 2.4.2.2) from Escherichia coli (strain K12) (see 80 papers)
UDP_ECOLI / P12758 Uridine phosphorylase; UPase; UrdPase; EC 2.4.2.3 from Escherichia coli (strain K12) (see 3 papers)
udp uridine phosphorylase; EC 2.4.2.3 from Escherichia coli K12 (see 9 papers)
28% identity, 92% coverage of query (91.3 bits)
Shewana3_3680 Uridine phosphorylase (EC 2.4.2.3) from Shewanella sp. ANA-3
30% identity, 81% coverage of query (91.3 bits)
Q9YDC0 purine-nucleoside phosphorylase (EC 2.4.2.1) from Aeropyrum pernix (see 2 papers)
30% identity, 84% coverage of query (91.3 bits)
4r2wD / Q8E9X9 X-ray structure of uridine phosphorylase from shewanella oneidensis mr-1 in complex with uridine at 1.6 a resolution (see paper)
30% identity, 81% coverage of query (91.3 bits)
SO4133 Uridine phosphorylase (EC 2.4.2.3) from Shewanella oneidensis MR-1
C7EWM3 uridine phosphorylase (EC 2.4.2.3) from Shewanella oneidensis (see 4 papers)
30% identity, 81% coverage of query (91.3 bits)
1u1eA Structure of e. Coli uridine phosphorylase complexed to 5(phenylseleno)acyclouridine (psau)
28% identity, 92% coverage of query (91.3 bits)
1u1dA Structure of e. Coli uridine phosphorylase complexed to 5- (phenylthio)acyclouridine (ptau)
28% identity, 92% coverage of query (91.3 bits)
1u1cA Structure of e. Coli uridine phosphorylase complexed to 5- benzylacyclouridine (bau)
28% identity, 92% coverage of query (91.3 bits)
1tgyA Structure of e. Coli uridine phosphorylase complexed with uracil and ribose 1-phosphate
28% identity, 92% coverage of query (91.3 bits)
1rxcJ E. Coli uridine phosphorylase: 5-fluorouracil ribose-1-phosphate complex
28% identity, 92% coverage of query (91.3 bits)
1rxcB E. Coli uridine phosphorylase: 5-fluorouracil ribose-1-phosphate complex
28% identity, 92% coverage of query (91.3 bits)
4r2wF X-ray structure of uridine phosphorylase from shewanella oneidensis mr-1 in complex with uridine at 1.6 a resolution
30% identity, 81% coverage of query (91.3 bits)
4u2kD X-ray structure uridine phosphorylase from vibrio cholerae in complex with anticancer compound at 2.13 a resolution
32% identity, 85% coverage of query (89.0 bits)
1rxcA E. Coli uridine phosphorylase: 5-fluorouracil ribose-1-phosphate complex
28% identity, 92% coverage of query (88.6 bits)
3kvvA Trapping of an oxocarbenium ion intermediate in up crystals
28% identity, 84% coverage of query (88.6 bits)
1u1fA Structure of e. Coli uridine phosphorylase complexed to 5-(m- (benzyloxy)benzyl)acyclouridine (bbau)
28% identity, 84% coverage of query (88.6 bits)
Q9K4U1 uridine phosphorylase (EC 2.4.2.3) from Vibrio cholerae (see 2 papers)
5efoB / Q9K4U1 X-ray structure uridine phosphorylase from vibrio cholerae in complex with cytidine and cytosine at 1.63a.
udp / CAB94933.1 uridine phosphorylase from Vibrio cholerae (see paper)
30% identity, 92% coverage of query (88.2 bits)
1u1gA Structure of e. Coli uridine phosphorylase complexed to 5-(m- (benzyloxy)benzyl)barbituric acid (bbba)
28% identity, 92% coverage of query (88.2 bits)
6rcaA X-ray structure uridine phosphorylase from vibrio cholerae in complex with 2.2'-anhydrouridine at 1.34 a
30% identity, 92% coverage of query (88.2 bits)
5efoE X-ray structure uridine phosphorylase from vibrio cholerae in complex with cytidine and cytosine at 1.63a.
30% identity, 92% coverage of query (88.2 bits)
5c80A X-ray structure uridine phosphorylase from vibrio cholerae in complex with uridine at 2.24 a resolution
30% identity, 92% coverage of query (88.2 bits)
1rxsB E. Coli uridine phosphorylase: 2'-deoxyuridine phosphate complex
29% identity, 77% coverage of query (88.2 bits)
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Lawrence Berkeley National Laboratory