Searching for up to 100 curated homologs for 1937094 b4477 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (NCBI) (205 a.a.)
Found high-coverage hits (≥70%) to 22 curated proteins.
Removed hits that are identical to the query, leaving 20
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
lgnG / BAM68210.1 2-keto-3-deoxy-6-phosphogalactonate aldolase lgnG from Paracoccus laeviglucosivorans (see 2 papers)
43% identity, 100% coverage of query (166 bits)
DGOA_RHIME / Q92RN8 Probable 2-dehydro-3-deoxy-6-phosphogalactonate aldolase; 2-oxo-3-deoxygalactonate 6-phosphate aldolase; 6-phospho-2-dehydro-3-deoxygalactonate aldolase; 6-phospho-2-keto-3-deoxygalactonate aldolase; KDPGal; EC 4.1.2.21 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
50% identity, 94% coverage of query (156 bits)
TM0066 / Q9WXS1 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16; EC 4.1.2.55) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
32% identity, 96% coverage of query (104 bits)
1wa3D / Q9WXS1 Mechanism of the class i kdpg aldolase (see paper)
32% identity, 96% coverage of query (104 bits)
D4GV57 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14) from Haloferax volcanii (see paper)
33% identity, 81% coverage of query (92.8 bits)
ALKH_BACSU / P50846 KHG/KDPG aldolase; EC 4.1.3.16; EC 4.1.2.14 from Bacillus subtilis (strain 168) (see paper)
31% identity, 83% coverage of query (90.5 bits)
Q0K1X1 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14) from Cupriavidus necator (see paper)
38% identity, 71% coverage of query (80.9 bits)
Build an alignment for 1937094 and 7 homologs with ≥ 30% identity
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Q00384 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14) from Zymomonas mobilis subsp. mobilis (see paper)
27% identity, 84% coverage of query (63.9 bits)
5xsfA / Q00384 Crystal structure of the 2-keto-3-deoxy-6-phosphogluconate aldolase of zymomonas mobilis zm4 with 3-phosphoglycerate
27% identity, 84% coverage of query (63.9 bits)
3vcrA / D2YW47 Crystal structure of a putative kdpg (2-keto-3-deoxy-6- phosphogluconate) aldolase from oleispira antarctica (see paper)
30% identity, 80% coverage of query (60.8 bits)
Kga / b1850 KHG/KDPG aldolase (EC 4.1.2.55; EC 4.1.2.14; EC 4.1.3.42; EC 4.1.1.112) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
eda / P0A955 KHG/KDPG aldolase (EC 4.1.2.55; EC 4.1.3.42; EC 4.1.1.112) from Escherichia coli (strain K12) (see 2 papers)
ALKH_ECOLI / P0A955 KHG/KDPG aldolase; EC 4.1.3.16; EC 4.1.2.14 from Escherichia coli (strain K12) (see 5 papers)
P0A955 4-Hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16); (4S)-4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.42) from Escherichia coli (see 5 papers)
eda / RF|NP_416364 KHG/KDPG aldolase; EC 4.1.2.14; EC 4.1.3.16 from Escherichia coli K12 (see 4 papers)
27% identity, 72% coverage of query (60.8 bits)
1euaA Schiff base intermediate in kdpg aldolase from escherichia coli
27% identity, 72% coverage of query (60.8 bits)
eda / CAE53635.1 2-dehydro-3-deoxyphosphogluconate aldolase from Nonomuraea gerenzanensis (see paper)
29% identity, 71% coverage of query (60.5 bits)
ALKD_PSEA6 / Q15X88 2-dehydro-3-deoxy-phosphogluconate aldolase; 2-keto-3-deoxy-6-phospho-D-gluconate aldolase; KDPG aldolase; EC 4.1.2.14 from Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
29% identity, 71% coverage of query (59.3 bits)
2c0aB / P0A955 Mechanism of the class i kdpg aldolase (see paper)
26% identity, 72% coverage of query (58.9 bits)
1wauA Structure of kdpg aldolase e45n mutant
26% identity, 72% coverage of query (58.9 bits)
6oviA / Q5ZYF2 Crystal structure of kdpg aldolase from legionella pneumophila with pyruvate captured at low ph as a covalent carbinolamine intermediate
25% identity, 80% coverage of query (58.5 bits)
P00885 2-dehydro-3-deoxy-phosphogluconate aldolase; KDPG-aldolase; Phospho-2-dehydro-3-deoxygluconate aldolase; Phospho-2-keto-3-deoxygluconate aldolase; EC 4.1.2.14 from Pseudomonas putida (Arthrobacter siderocapsulatus)
27% identity, 94% coverage of query (57.0 bits)
1mxsA / P00885 Crystal structure of 2-keto-3-deoxy-6-phosphogluconate (kdpg) aldolase from pseudomonas putida. (see paper)
28% identity, 78% coverage of query (54.7 bits)
kdgA / P38448 2-dehydro-3-deoxy-D-gluconate-6-phosphate aldolase (EC 4.1.2.55) from Dickeya dadantii (strain 3937) (see 2 papers)
25% identity, 80% coverage of query (53.9 bits)
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Lawrence Berkeley National Laboratory