Searching for up to 100 curated homologs for 199630 FitnessBrowser__MR1:199630 (267 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
HSD1 / P0DKC5 11β-, 17β-hydroxysteroid dehydrogenase / 17β-ketosteroid reductase (EC 1.1.1.62; EC 1.1.1.146) from Arabidopsis thaliana (see 3 papers)
HSD1A_ARATH / P0DKC5 11-beta-hydroxysteroid dehydrogenase 1A; 17-beta-hydroxysteroid dehydrogenase 1A; Hydroxysteroid dehydrogenase 1; AtHSD1; EC 1.1.1.146; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
HSD1B_ARATH / P0DKC6 11-beta-hydroxysteroid dehydrogenase 1B; 17-beta-hydroxysteroid dehydrogenase 1B; Hydroxysteroid dehydrogenase 1; AtHSD1; EC 1.1.1.146; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
35% identity, 99% coverage of query (156 bits)
HSDA_SESIN / Q93W57 11-beta-hydroxysteroid dehydrogenase A; 17-beta-hydroxysteroid dehydrogenase A; Seed oil body protein 2; Steroleosin-A; EC 1.1.1.-; EC 1.1.1.62 from Sesamum indicum (Oriental sesame) (Sesamum orientale) (see 3 papers)
35% identity, 97% coverage of query (155 bits)
HSDA_ARAHY / A7LB60 11-beta-hydroxysteroid dehydrogenase A; 17-beta-hydroxysteroid dehydrogenase A; Steroleosin-A; EC 1.1.1.146; EC 1.1.1.- from Arachis hypogaea (Peanut) (see paper)
34% identity, 97% coverage of query (146 bits)
HSDB_SESIN / Q8LKV5 11-beta-hydroxysteroid dehydrogenase B; 17-beta-hydroxysteroid dehydrogenase B; Seed oil body protein 3; Steroleosin-B; EC 1.1.1.146; EC 1.1.1.62 from Sesamum indicum (Oriental sesame) (Sesamum orientale) (see 2 papers)
37% identity, 72% coverage of query (135 bits)
DHRS7_HUMAN / Q9Y394 Dehydrogenase/reductase SDR family member 7; Retinal short-chain dehydrogenase/reductase 4; retSDR4; Short chain dehydrogenase/reductase family 34C member 1; Protein SDR34C1; EC 1.1.1.- from Homo sapiens (Human) (see 5 papers)
36% identity, 98% coverage of query (134 bits)
HSD_PINMS / A0A140FAN3 11-beta-hydroxysteroid dehydrogenase; 17-beta-hydroxysteroid dehydrogenase; Steroleosin; EC 1.1.1.146; EC 1.1.1.62 from Pinus massoniana (Chinese red pine) (see paper)
33% identity, 97% coverage of query (133 bits)
HSDB_ARAHY / A7LB59 11-beta-hydroxysteroid dehydrogenase B; 17-beta-hydroxysteroid dehydrogenase B; Steroleosin-B; EC 1.1.1.146; EC 1.1.1.- from Arachis hypogaea (Peanut) (see paper)
40% identity, 72% coverage of query (128 bits)
DRS7B_RAT / Q5RJY4 Dehydrogenase/reductase SDR family member 7B; Short-chain dehydrogenase/reductase family 32C member 1; Protein SDR32C1; EC 1.1.-.- from Rattus norvegicus (Rat) (see 2 papers)
30% identity, 96% coverage of query (126 bits)
AT1G24360 / P33207 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplastic (EC 1.1.1.100) from Arabidopsis thaliana (see paper)
33% identity, 81% coverage of query (117 bits)
phaB / BAC45231.1 3-keto-acyl-CoA reductase from Bacillus sp. INT005 (see paper)
35% identity, 71% coverage of query (116 bits)
1edoA / Q93X62 The x-ray structure of beta-keto acyl carrier protein reductase from brassica napus complexed with NADP+ (see paper)
34% identity, 76% coverage of query (115 bits)
DRS7C_RAT / D3ZGP9 Dehydrogenase/reductase SDR family member 7C; Sarcoplasmic reticulum protein of 35 kDa; Protein SRP-35; Short-chain dehydrogenase/reductase family 32C member 2; Protein SDR32C2; EC 1.1.1.105 from Rattus norvegicus (Rat) (see paper)
36% identity, 70% coverage of query (113 bits)
DRS7C_MOUSE / Q8CHS7 Dehydrogenase/reductase SDR family member 7C; Sarcoplasmic reticulum protein of 35 kDa; Protein SRP-35; Short-chain dehydrogenase/reductase family 32C member 2; Protein SDR32C2; EC 1.1.1.105 from Mus musculus (Mouse) (see 4 papers)
36% identity, 70% coverage of query (113 bits)
5yssB / A0A0D7LY80 Crystal structure of aminocaproic acid cyclase in complex with NAD (+) (see paper)
32% identity, 83% coverage of query (110 bits)
fabG / P51831 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Bacillus subtilis (strain 168) (see 3 papers)
33% identity, 77% coverage of query (108 bits)
Q86RB1 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Plasmodium falciparum (see paper)
30% identity, 82% coverage of query (105 bits)
KDSR / Q06136 3-ketodihydrosphingosine reductase (EC 1.1.1.102) from Homo sapiens (see 2 papers)
KDSR_HUMAN / Q06136 3-ketodihydrosphingosine reductase; KDS reductase; 3-dehydrosphinganine reductase; Follicular variant translocation protein 1; FVT-1; Short chain dehydrogenase/reductase family 35C member 1; EC 1.1.1.102 from Homo sapiens (Human) (see 3 papers)
Q06136 3-dehydrosphinganine reductase (EC 1.1.1.102) from Homo sapiens (see paper)
KDSR / GI|30582403 3-ketodihydrosphingosine reductase; EC 1.1.1.102 from Homo sapiens (see paper)
30% identity, 97% coverage of query (104 bits)
V9NF79 diacetyl reductase [(R)-acetoin forming] (EC 1.1.1.303) from Paenibacillus polymyxa (see paper)
35% identity, 71% coverage of query (103 bits)
2q2qD / Q9AE70 Structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas putida (see paper)
30% identity, 87% coverage of query (103 bits)
Q9AE70 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Pseudomonas putida (see 2 papers)
30% identity, 87% coverage of query (102 bits)
DHI1_SAISC / Q29608 11-beta-hydroxysteroid dehydrogenase 1; 11-DH; 11-beta-HSD1; 7-oxosteroid reductase; Corticosteroid 11-beta-dehydrogenase isozyme 1; EC 1.1.1.146; EC 1.1.1.201 from Saimiri sciureus (Common squirrel monkey) (see paper)
33% identity, 82% coverage of query (102 bits)
G0HY85 acetoacetyl-CoA reductase (EC 1.1.1.36) from Haloarcula hispanica (see paper)
35% identity, 70% coverage of query (102 bits)
Build an alignment for 199630 and 22 homologs with ≥ 30% identity
Or download the sequences
LOC100862709 / H6AGY1 3-dehydroecdysone-3α-reductase from Bombyx mori (see 2 papers)
27% identity, 86% coverage of query (101 bits)
PK81I_PSEFD / M2ZIX7 Short chain dehydrogenase MYCFIDRAFT_6125; PKS8-1 gene cluster protein MYCFIDRAFT_6125; EC 1.1.1.- from Pseudocercospora fijiensis (strain CIRAD86) (Black leaf streak disease fungus) (Mycosphaerella fijiensis) (see 2 papers)
35% identity, 78% coverage of query (100 bits)
6d9yB / B2JLJ0 Crystal structure of a short chain dehydrogenase/reductase sdr from burkholderia phymatum with partially occupied NAD
36% identity, 71% coverage of query (100 bits)
C0BWQ2 12alpha-hydroxysteroid dehydrogenase (EC 1.1.1.176) from [Clostridium] hylemonae (see paper)
33% identity, 72% coverage of query (100 bits)
FABG_SYNY3 / P73574 3-oxoacyl-[acyl-carrier-protein] reductase; 3-ketoacyl-acyl carrier protein reductase; EC 1.1.1.100 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
35% identity, 73% coverage of query (100 bits)
6ci9D / A0QP46 Rmm microcompartment-associated aminopropanol dehydrogenase NADP + aminoacetone holo-structure (see paper)
32% identity, 70% coverage of query (100 bits)
Q767A0 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Acidovorax sp. (see paper)
28% identity, 87% coverage of query (99.8 bits)
3op4A Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from vibrio cholerae o1 biovar eltor str. N16961 in complex with NADP+ (see paper)
35% identity, 72% coverage of query (99.0 bits)
A1U3L3 alcohol-forming fatty acyl-CoA reductase (EC 1.2.1.84) from Marinobacter nauticus (see paper)
29% identity, 94% coverage of query (99.0 bits)
O73949 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Pyrococcus furiosus (see paper)
33% identity, 81% coverage of query (98.2 bits)
4i08A Crystal structure of beta-ketoacyl-acyl carrier protein reductase (fabg) from vibrio cholerae in complex with NADPH
35% identity, 71% coverage of query (98.2 bits)
4qecA / I6ZQW6 Elxo with NADP bound (see paper)
28% identity, 72% coverage of query (97.8 bits)
FABG_AQUAE / O67610 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Aquifex aeolicus (strain VF5)
32% identity, 83% coverage of query (97.8 bits)
F6WB20 all-trans-retinol dehydrogenase (NAD+) (EC 1.1.1.105) from Ciona intestinalis (see paper)
30% identity, 87% coverage of query (97.1 bits)
Q9I1X3 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50) from Pseudomonas aeruginosa (see paper)
31% identity, 78% coverage of query (97.1 bits)
RDH8_BOVIN / Q9N126 Retinol dehydrogenase 8; Photoreceptor outer segment all-trans retinol dehydrogenase; EC 1.1.1.300 from Bos taurus (Bovine) (see paper)
34% identity, 72% coverage of query (97.1 bits)
3gmdA Structure-based design of 7-azaindole-pyrrolidines as inhibitors of 11beta-hydroxysteroid-dehydrogenase type i
32% identity, 73% coverage of query (96.3 bits)
1xhlA / Q19774 Crystal structure of putative tropinone reductase-ii from caenorhabditis elegans with cofactor and substrate
33% identity, 70% coverage of query (95.9 bits)
8fd8A / P15428 Human 15-pgdh with nadh bound (see paper)
32% identity, 74% coverage of query (95.9 bits)
1xhlB Crystal structure of putative tropinone reductase-ii from caenorhabditis elegans with cofactor and substrate
33% identity, 70% coverage of query (95.9 bits)
Q8RR58 long-chain acyl-protein thioester reductase (EC 1.2.1.50) from Acinetobacter sp. (see paper)
29% identity, 93% coverage of query (95.5 bits)
HPGD / P15428 15-hydroxyprostaglandin dehydrogenase [NAD+] monomer (EC 1.1.1.141; EC 1.1.1.232) from Homo sapiens (see 6 papers)
PGDH_HUMAN / P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; 15-PGDH; Eicosanoid/docosanoid dehydrogenase [NAD(+)]; Prostaglandin dehydrogenase 1; Short chain dehydrogenase/reductase family 36C member 1; EC 1.1.1.141; EC 1.1.1.-; EC 1.1.1.232 from Homo sapiens (Human) (see 13 papers)
P15428 15-hydroxyprostaglandin dehydrogenase (NAD+) (EC 1.1.1.141); 13,14-dehydro-15-oxoprostaglandin 13-reductase (EC 1.3.1.48) from Homo sapiens (see 11 papers)
33% identity, 71% coverage of query (95.5 bits)
4ijuB / P28845 Crystal structure of 11b-hsd1 double mutant (l262r, f278e) in complex with (1s,4s)-4-[8-(2-fluorophenoxy)[1,2,4]triazolo[4,3-a]pyridin-3- yl]bicyclo[2.2.1]heptan-1-ol (see paper)
33% identity, 73% coverage of query (95.5 bits)
2gdzA / P15428 Crystal structure of 15-hydroxyprostaglandin dehydrogenase type1, complexed with NAD+ (see paper)
33% identity, 71% coverage of query (95.5 bits)
8cwlA Cryo-em structure of human 15-pgdh in complex with small molecule sw222746
33% identity, 71% coverage of query (95.5 bits)
8cvnA Cryo-em structure of human 15-pgdh in complex with small molecule sw209415
33% identity, 71% coverage of query (95.5 bits)
3oq1A Crystal structure of 11beta-hydroxysteroid dehydrogenase-1 (11b-hsd1) in complex with diarylsulfone inhibitor
33% identity, 73% coverage of query (95.5 bits)
3hfgA Crystal structure of human 11-beta-hydroxysteroid-dehydrogenase bound to an sulfonyl-piperazine inhibitor
33% identity, 73% coverage of query (95.5 bits)
3byzA 2-amino-1,3-thiazol-4(5h)-ones as potent and selective 11- hydroxysteroid dehydrogenase type 1 inhibitors
33% identity, 73% coverage of query (95.5 bits)
TRII / CAB52307.1 tropinone reductase II from Solanum tuberosum (see paper)
31% identity, 71% coverage of query (95.1 bits)
T4HR_ZYMTI / F9XMW6 Probable tetrahydroxynaphthalene reductase MYCGRDRAFT_87994; Conidial pigment biosynthesis cluster 29 protein MYCGRDRAFT_87994; EC 1.1.1.252 from Zymoseptoria tritici (strain CBS 115943 / IPO323) (Speckled leaf blotch fungus) (Septoria tritici) (see paper)
29% identity, 71% coverage of query (95.1 bits)
PGDH_MOUSE / Q8VCC1 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; 15-PGDH; Eicosanoid/docosanoid dehydrogenase [NAD(+)]; Prostaglandin dehydrogenase 1; EC 1.1.1.141; EC 1.1.1.-; EC 1.1.1.232 from Mus musculus (Mouse) (see 2 papers)
Q8VCC1 15-hydroxyprostaglandin dehydrogenase (NAD+) (EC 1.1.1.141) from Mus musculus (see paper)
33% identity, 71% coverage of query (95.1 bits)
4jroC / Q8Y690 Crystal structure of 3-oxoacyl-[acyl-carrier protein]reductase (fabg) from listeria monocytogenes in complex with NADP+
32% identity, 72% coverage of query (95.1 bits)
E2QX67 15-hydroxyprostaglandin dehydrogenase (NAD+) (EC 1.1.1.141) from Canis lupus familiaris (see paper)
33% identity, 71% coverage of query (95.1 bits)
Q5KST5 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Pseudomonas fragi (see 3 papers)
1wmbA / Q5KST5 Crystal structure of NAD dependent d-3-hydroxybutylate dehydrogenase (see paper)
BAD86668.1 D(-)-3-hydroxybutyrate dehydrogenase from Pseudomonas fragi (see paper)
30% identity, 83% coverage of query (95.1 bits)
4ijvA Crystal structure of 11b-hsd1 double mutant (l262r, f278e) in complex with 3-[1-(4-chlorophenyl)cyclopropyl]-8-(2-fluorophenoxy)[1,2, 4]triazolo[4,3-a]pyridine
33% identity, 73% coverage of query (95.1 bits)
3fcoA Crystal structure of 11beta-hydroxysteroid dehydrogenase 1 (11b-hsd1) in complex with benzamide inhibitor
33% identity, 73% coverage of query (95.1 bits)
2belA Structure of human 11-beta-hydroxysteroid dehydrogenase in complex with NADP and carbenoxolone
33% identity, 73% coverage of query (95.1 bits)
3frjB Crystal structure of 11b-hydroxysteroid dehydrogenase-1 (11b-hsd1) in complex with piperidyl benzamide inhibitor
33% identity, 73% coverage of query (95.1 bits)
5pgyA Crystal structure of 11beta-hsd1 double mutant (l262r, f278e) complexed with 2-[(5r,7s)-6-hydroxy-2-phenyladamantan-2-yl]-1-(3- hydroxyazetidin-1-yl)ethan-1-one (bms-816336)
33% identity, 73% coverage of query (95.1 bits)
4ijwA Crystal structure of 11b-hsd1 double mutant (l262r, f278e) in complex with 3-[1-(4-chlorophenyl)cyclopropyl]-8-cyclopropyl[1,2, 4]triazolo[4,3-a]pyridine
33% identity, 73% coverage of query (95.1 bits)
3ey4A Further studies with the 2-amino-1,3-thiazol-4(5h)-one class of 11- hydroxysteroid dehydrogenase type 1 (11-hsd1) inhibitors: reducing pregnane x receptor (pxr) activity and exploring activity in a monkey pharmacodynamic model
33% identity, 73% coverage of query (95.1 bits)
3czrA Crystal structure of human 11-beta-hydroxysteroid dehydrogenase (hsd1) in complex with arylsulfonylpiperazine inhibitor
33% identity, 73% coverage of query (95.1 bits)
4k1lA 4,4-dioxo-5,6-dihydro-[1,4,3]oxathiazines, a novel class of 11 beta- hsd1 inhibitors for the treatment of diabetes
33% identity, 73% coverage of query (95.1 bits)
1xu7A Crystal structure of the interface open conformation of tetrameric 11b-hsd1
33% identity, 73% coverage of query (95.1 bits)
5pgwA Crystal structure of 11beta-hsd1 double mutant (l262r, f278e) complexed with 2-[(1r,3s,5r,7s)-2-[4-(4-fluorophenyl)phenyl]-6- hydroxyadamantan-2-yl]-1-(3- hydroxyazetidin-1-yl)ethan-1-one
33% identity, 73% coverage of query (95.1 bits)
5qiiA Crystal structure of 11beta-hsd1 double mutant (l262r, f278e) complexed with 2-(3-(1-(4-chlorophenyl)cyclopropyl) -[1,2, 4]triazolo[4,3-a]pyridin-8-yl)propan-2-ol
33% identity, 73% coverage of query (95.1 bits)
5pgxA Crystal structure of 11beta-hsd1 double mutant (l262r, f278e) complexed with 2-(2-benzyl-6-hydroxyadamantan-2-yl)-1-(3- hydroxyazetidin-1-yl)ethan-1-one
33% identity, 73% coverage of query (95.1 bits)
5pgvA Crystal structure of 11beta-hsd1 double mutant (l262r, f278e) complexed with 1-(3-hydroxyazetidin-1-yl)-2-[(2s,5r)-2-(4- fluorophenyl)-5-methoxyadamantan-2-yl]ethan-1-one
33% identity, 73% coverage of query (95.1 bits)
5pguA Crystal structure of 11beta-hsd1 double mutant (l262r, f278e) complexed with 2-[2-(4-fluorophenyl)-2-adamantyl]-1-(3- methoxyazetidin-1-yl)ethanone
33% identity, 73% coverage of query (95.1 bits)
3tfqA Crystal structure of 11b-hsd1 double mutant (l262r, f278e) complexed with 8-{[(2-cyanopyridin-3-yl)methyl]sulfanyl}-6-hydroxy-3,4-dihydro- 1h-pyrano[3,4-c]pyridine-5-carbonitrile
33% identity, 73% coverage of query (95.1 bits)
3d3eA Crystal structure of human 11-beta-hydroxysteroid dehydrogenase (hsd1) in complex with benzamide inhibitor
33% identity, 73% coverage of query (95.1 bits)
3ch6A Crystal structure of 11beta-hsd1 double mutant (l262r, f278e) complexed with (3,3-dimethylpiperidin-1-yl)(6-(3-fluoro-4- methylphenyl)pyridin-2-yl)methanone
33% identity, 73% coverage of query (95.1 bits)
2rbeA The discovery of 2-anilinothiazolones as 11beta-hsd1 inhibitors
33% identity, 73% coverage of query (95.1 bits)
4hx5A Crystal structure of 11 beta-hsd1 in complex with sar184841
33% identity, 73% coverage of query (95.1 bits)
3pdjA Crystal structure of human 11-beta-hydroxysteroid dehydrogenase 1 (11b-hsd1) in complex with 4,4-disubstituted cyclohexylbenzamide inhibitor
33% identity, 73% coverage of query (95.1 bits)
2iltA Human 11-beta-hydroxysteroid dehydrogenase (hsd1) with NADP and adamantane sulfone inhibitor
33% identity, 73% coverage of query (95.1 bits)
3h6kA Crystal structure of human 11-beta-hydroxysteroid-dehydrogenase bound to an ortho-chlro-sulfonyl-piperazine inhibitor
33% identity, 73% coverage of query (95.1 bits)
2irwA Human 11-beta-hydroxysteroid dehydrogenase (hsd1) with NADP and adamantane ether inhibitor
33% identity, 73% coverage of query (95.1 bits)
4c7jA 11b-hydroxysteroid dehydrogenase type i in complex with inhibitor
33% identity, 73% coverage of query (95.1 bits)
3qqpA Crystal structure of 11beta-hydroxysteroid dehydrogenase 1 (11b-hsd1) in complex with urea inhibitor
33% identity, 73% coverage of query (95.1 bits)
2ztlA Closed conformation of d-3-hydroxybutyrate dehydrogenase complexed with NAD+ and l-3-hydroxybutyrate
30% identity, 83% coverage of query (95.1 bits)
3bzuA Crystal structure of human 11-beta-hydroxysteroid dehydrogenase(hsd1) in complex with NADP and thiazolone inhibitor
33% identity, 73% coverage of query (95.1 bits)
4c7kA 11b-hydroxysteroid dehydrogenase type i in complex with inhibitor
33% identity, 73% coverage of query (95.1 bits)
4yyzA 11b-hydroxysteroid dehydrogenase type i in complex with inhibitor
33% identity, 73% coverage of query (95.1 bits)
RDH8 / Q9NYR8 retinol dehydrogenase 8 (EC 1.1.1.300) from Homo sapiens (see 2 papers)
RDH8_HUMAN / Q9NYR8 Retinol dehydrogenase 8; Photoreceptor outer segment all-trans retinol dehydrogenase; Short chain dehydrogenase/reductase family 28C member 2; EC 1.1.1.300 from Homo sapiens (Human) (see paper)
Q9NYR8 NADP-retinol dehydrogenase (EC 1.1.1.300) from Homo sapiens (see 2 papers)
34% identity, 72% coverage of query (94.7 bits)
4nbuB Crystal structure of fabg from bacillus sp (see paper)
31% identity, 77% coverage of query (94.7 bits)
YM71_YEAST / Q05016 NADP-dependent 3-hydroxy acid dehydrogenase; L-allo-threonine dehydrogenase; EC 1.1.1.-; EC 1.1.1.381 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
Q05016 3-hydroxy acid dehydrogenase (EC 1.1.1.381) from Saccharomyces cerevisiae (see paper)
35% identity, 71% coverage of query (94.7 bits)
4bb5A Free-wilson and structural approaches to co-optimising human and rodent isoform potency for 11b-hydroxysteroid dehydrogenase type 1 11b-hsd1 inhibitors
33% identity, 73% coverage of query (94.7 bits)
3rkuA / Q05016 Substrate fingerprint and the structure of NADP+ dependent serine dehydrogenase from saccharomyces cerevisiae complexed with NADP+
35% identity, 71% coverage of query (94.7 bits)
HSD11B1 / P28845 corticosteroid 11-beta-dehydrogenase isozyme 1 (EC 1.1.1.146) from Homo sapiens (see 7 papers)
DHI1_HUMAN / P28845 11-beta-hydroxysteroid dehydrogenase 1; 11-DH; 11-beta-HSD1; 7-oxosteroid reductase; Corticosteroid 11-beta-dehydrogenase isozyme 1; Short chain dehydrogenase/reductase family 26C member 1; EC 1.1.1.146; EC 1.1.1.201 from Homo sapiens (Human) (see 22 papers)
P28845 11beta-hydroxysteroid dehydrogenase (EC 1.1.1.146) from Homo sapiens (see 51 papers)
33% identity, 73% coverage of query (94.7 bits)
4p38A Human 11beta-hydroxysteroid dehydrogenase type 1 in complex with azd8329
33% identity, 73% coverage of query (94.7 bits)
4bb6A Free-wilson and structural approaches to co-optimising human and rodent isoform potency for 11b-hydroxysteroid dehydrogenase type 1 11b-hsd1 inhibitors
33% identity, 73% coverage of query (94.7 bits)
1x1tA / Q5KST5 Crystal structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas fragi complexed with NAD+ (see paper)
32% identity, 72% coverage of query (94.7 bits)
A0A1E3M3N6 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Acinetobacter baumannii (see paper)
6zzsD / A0A1E3M3N6 Crystal structure of (r)-3-hydroxybutyrate dehydrogenase from acinetobacter baumannii complexed with NAD+ and 3-oxovalerate (see paper)
27% identity, 85% coverage of query (94.4 bits)
6zzqA Crystal structure of (r)-3-hydroxybutyrate dehydrogenase from acinetobacter baumannii complexed with NAD+ and acetoacetate
27% identity, 85% coverage of query (94.0 bits)
TR1 / P50162 tropinone reductase (EC 1.1.1.206) from Datura stramonium (see paper)
TRN1_DATST / P50162 Tropinone reductase 1; Tropine dehydrogenase; Tropinone reductase I; TR-I; EC 1.1.1.206 from Datura stramonium (Jimsonweed) (Common thornapple) (see 2 papers)
P50162 tropinone reductase I (EC 1.1.1.206) from Datura stramonium (see 2 papers)
31% identity, 79% coverage of query (94.0 bits)
1ae1B / P50162 Tropinone reductase-i complex with NADP (see paper)
31% identity, 79% coverage of query (94.0 bits)
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