Sites on a Tree

 

Searching for up to 100 curated homologs for 201387 FitnessBrowser__MR1:201387 (567 a.a.)

Found high-coverage hits (≥70%) to 39 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q8R7R4 phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
    37% identity, 99% coverage of query (388 bits)

2hwgA / P08839 Structure of phosphorylated enzyme i of the phosphoenolpyruvate:sugar phosphotransferase system (see paper)
    36% identity, 99% coverage of query (348 bits)

P0A249 phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    36% identity, 99% coverage of query (348 bits)

Ctr / b2416 PTS enzyme I (EC 2.7.3.9) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
ptsI / P08839 PTS enzyme I (EC 2.7.3.9) from Escherichia coli (strain K12) (see 66 papers)
PT1_ECOLI / P08839 Phosphoenolpyruvate-protein phosphotransferase; Phosphotransferase system, enzyme I; EC 2.7.3.9 from Escherichia coli (strain K12) (see 3 papers)
P08839 phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) from Escherichia coli (see 4 papers)
ptsI / GB|AAC75469.1 phosphoenolpyruvate-protein phosphotransferase; EC 2.7.3.9 from Escherichia coli K12 (see 14 papers)
    36% identity, 99% coverage of query (348 bits)

PT1_STACT / P23533 Phosphoenolpyruvate-protein phosphotransferase; Phosphotransferase system, enzyme I; EC 2.7.3.9 from Staphylococcus carnosus (strain TM300) (see 2 papers)
P23533 phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) from Staphylococcus carnosus (see 3 papers)
    36% identity, 97% coverage of query (340 bits)

A0A0H2ZMY1 phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) from Streptococcus pneumoniae (see paper)
    34% identity, 99% coverage of query (337 bits)

P30299 phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) from Streptococcus salivarius (see paper)
    35% identity, 97% coverage of query (333 bits)

PT1_BACSU / P08838 Phosphoenolpyruvate-protein phosphotransferase; Phosphotransferase system, enzyme I; EC 2.7.3.9 from Bacillus subtilis (strain 168) (see paper)
P08838 phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) from Bacillus subtilis (see paper)
    35% identity, 94% coverage of query (326 bits)

PT1_STAAU / P51183 Phosphoenolpyruvate-protein phosphotransferase; Phosphotransferase system, enzyme I; EC 2.7.3.9 from Staphylococcus aureus (see paper)
    34% identity, 99% coverage of query (325 bits)

ptsI / AAA86049.1 PTS enzyme I from Geobacillus stearothermophilus (see paper)
    35% identity, 96% coverage of query (325 bits)

TC 4.A.2.1.17 / Q9HY55 Phosphotransferase system transporter enzyme I, FruI, component of Fructose-specific PTS permease, FruIIBC/FruI-HPr-IIA from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    41% identity, 84% coverage of query (323 bits)

2wqdA / P51183 Crystal structure of enzyme i of the phosphoenolpyruvate:sugar phosphotransferase system in the dephosphorylated state (see paper)
    34% identity, 99% coverage of query (322 bits)

PS417_03965 fructose-specific PTS system (fructose 1-phosphate forming), EI, Hpr, and EII-A components from Pseudomonas simiae WCS417
    39% identity, 84% coverage of query (319 bits)

Pf1N1B4_1146 fructose-specific PTS system (fructose 1-phosphate forming), EI, Hpr, and EII-A components from Pseudomonas fluorescens FW300-N1B4
    39% identity, 84% coverage of query (318 bits)

AO356_07335 fructose-specific PTS system (fructose 1-phosphate forming), EI, Hpr, and EII-A components from Pseudomonas fluorescens FW300-N2C3
    35% identity, 99% coverage of query (315 bits)

PT1_LACLC / Q9ZAD8 Phosphoenolpyruvate-protein phosphotransferase; Phosphotransferase system, enzyme I; EC 2.7.3.9 from Lactococcus lactis subsp. cremoris (Streptococcus cremoris) (see paper)
    34% identity, 97% coverage of query (315 bits)

AO353_05485 Fructose-specific PTS system, I, HPr, and IIA components from Pseudomonas fluorescens FW300-N2E3
    38% identity, 84% coverage of query (315 bits)

PT1_LYSSH / Q84F83 Phosphoenolpyruvate-protein phosphotransferase; Phosphotransferase system, enzyme I; EC 2.7.3.9 from Lysinibacillus sphaericus (Bacillus sphaericus) (see paper)
    35% identity, 96% coverage of query (313 bits)

PT1_ENTFA / P23530 Phosphoenolpyruvate-protein phosphotransferase; Phosphotransferase system, enzyme I; EC 2.7.3.9 from Enterococcus faecalis (strain ATCC 700802 / V583) (see paper)
    32% identity, 97% coverage of query (311 bits)

ptsI / AAC45391.1 enzyme I from Lactobacillus sakei (see paper)
    34% identity, 97% coverage of query (307 bits)

PT1_MYCCT / P45617 Phosphoenolpyruvate-protein phosphotransferase; Phosphotransferase system, enzyme I; EC 2.7.3.9 from Mycoplasma capricolum subsp. capricolum (strain California kid / ATCC 27343 / NCTC 10154) (see paper)
    32% identity, 97% coverage of query (301 bits)

Psest_3355 fructose-specific PTS system (fructose 1-phosphate forming), EI, Hpr, and EII-A components from Pseudomonas stutzeri RCH2
    39% identity, 84% coverage of query (300 bits)

PT1_HALVD / D4GYE2 Phosphoenolpyruvate-protein phosphotransferase; Phosphotransferase system, enzyme I; EC 2.7.3.9 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
    36% identity, 88% coverage of query (293 bits)

phbI / AAA21978.1 protein I from Cupriavidus necator (see paper)
    35% identity, 97% coverage of query (285 bits)

PS417_23035 D-trehalose PTS system, I, HPr, and IIA components from Pseudomonas simiae WCS417
    33% identity, 99% coverage of query (284 bits)

PTFAX_XANCP / P45597 Multiphosphoryl transfer protein; MTP; Triphosphoryl transfer protein; TTP; EC 2.7.3.9 from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
    36% identity, 97% coverage of query (283 bits)

AZOBR_RS32325 Fructose PTS system (E-I, HPr, and E-IIA components) from Azospirillum brasilense Sp245
    36% identity, 97% coverage of query (277 bits)

AO353_04460 N-acetylglucosamine-specific PTS system, I, HPr, and IIA components (nagF) from Pseudomonas fluorescens FW300-N2E3
    36% identity, 89% coverage of query (276 bits)

Q9KZP1 phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) from Streptomyces coelicolor (see 3 papers)
    35% identity, 95% coverage of query (271 bits)

AO353_15995 trehalose-specific PTS system, I, HPr, and IIA components from Pseudomonas fluorescens FW300-N2E3
    36% identity, 97% coverage of query (270 bits)

TC 4.A.2.1.26 / Q5V5X2 Phosphoenolpyruvate-protein phosphotransferase, component of Fructose-specific Enzyme I-HPr-Enzyme IIABC complex, all encoded within a single operon with genes in the order: ptsC (IIC), ptsA (IIA), ptsH (HPr), ptsI (Enzyme I) and ptsB (IIB) from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)
    35% identity, 90% coverage of query (270 bits)

PtsP / b2829 phosphoenolpyruvate-protein phosphotransferase PtsP from Escherichia coli K-12 substr. MG1655 (see 6 papers)
PtsP / P37177 phosphoenolpyruvate-protein phosphotransferase PtsP from Escherichia coli (strain K12) (see 6 papers)
PT1P_ECOLI / P37177 Phosphoenolpyruvate-dependent phosphotransferase system; Enzyme I-Ntr; EINtr; Phosphotransferase system, enzyme I; EC 2.7.3.9 from Escherichia coli (strain K12) (see 2 papers)
    35% identity, 83% coverage of query (269 bits)

FrwA / b3947 putative PTS multiphosphoryl transfer protein PtsA from Escherichia coli K-12 substr. MG1655 (see 4 papers)
    35% identity, 86% coverage of query (268 bits)

BPHYT_RS02740 N-acetylglucosamine-specific PTS system, I, HPr, and IIA components (nagF) from Burkholderia phytofirmans PsJN
    34% identity, 94% coverage of query (262 bits)

FryA / b2383 putative PTS multiphosphoryl transfer protein FryA from Escherichia coli K-12 substr. MG1655 (see 4 papers)
fryA / RF|NP_416884 multiphosphoryl transfer protein 1 from Escherichia coli K12 (see paper)
    33% identity, 99% coverage of query (262 bits)

TC 4.A.1.1.15 / Q9HXN5 N-Acetyl-D-Glucosamine phosphotransferase system transporter, component of N-acetyl glucosamine-specific PTS permease, GlcNAc IIBC/GlcNAc I-HPr-IIA from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    35% identity, 95% coverage of query (260 bits)

AO356_17540 N-acetylglucosamine-specific PTS system, I, HPr, and IIA components (nagF) from Pseudomonas fluorescens FW300-N2C3
    35% identity, 90% coverage of query (256 bits)

Q8NP83 phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) from Corynebacterium glutamicum (see paper)
    35% identity, 78% coverage of query (226 bits)

Build an alignment

Build an alignment for 201387 and 38 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

Q02KR1 Phosphoenolpyruvate synthase; PEP synthase; Pyruvate, water dikinase; EC 2.7.9.2 from Pseudomonas aeruginosa (strain UCBPP-PA14)
    26% identity, 72% coverage of query (102 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory