Searching for up to 100 curated homologs for 202036 FitnessBrowser__MR1:202036 (760 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Pfl / b0903 pyruvate formate-lyase from Escherichia coli K-12 substr. MG1655 (see 3 papers)
pflB / P09373 pyruvate formate-lyase from Escherichia coli (strain K12) (see 28 papers)
PFLB_ECOLI / P09373 Formate acetyltransferase 1; Pyruvate formate-lyase 1; EC 2.3.1.54 from Escherichia coli (strain K12) (see 3 papers)
P09373 formate C-acetyltransferase (EC 2.3.1.54) from Escherichia coli (see 10 papers)
    81% identity, 100% coverage of query (1332 bits)

1h16A Pyruvate formate-lyase (e.Coli) in complex with pyruvate and coa
    81% identity, 100% coverage of query (1329 bits)

1cm5A / P09373 Crystal structure of c418a,c419a mutant of pfl from e.Coli (see paper)
    81% identity, 100% coverage of query (1324 bits)

TDCE_ECOLI / P42632 PFL-like enzyme TdcE; Keto-acid formate acetyltransferase; Keto-acid formate-lyase; Ketobutyrate formate-lyase; KFL; Pyruvate formate-lyase; PFL; EC 2.3.1.-; EC 2.3.1.54 from Escherichia coli (strain K12) (see paper)
tdcE / EW|b3114 pyruvate formate-lyase 4/2-ketobutyrate formate-lyase from Escherichia coli K12 (see paper)
    76% identity, 99% coverage of query (1234 bits)

PFLB_STAAC / Q5HJF4 Formate acetyltransferase; Pyruvate formate-lyase; EC 2.3.1.54 from Staphylococcus aureus (strain COL) (see paper)
    64% identity, 100% coverage of query (1040 bits)

pfl / Q46266 pyruvate formate-lyase subunit (EC 2.3.1.54) from Clostridium pasteurianum (see 6 papers)
Q46266 formate C-acetyltransferase (EC 2.3.1.54) from Clostridium pasteurianum (see paper)
    62% identity, 99% coverage of query (949 bits)

PFL1 / Q1RS83 pyruvate formate lyase (EC 2.3.1.54) from Chlamydomonas reinhardtii (see 6 papers)
Q1RS83 formate C-acetyltransferase (EC 2.3.1.54) from Chlamydomonas reinhardtii (see paper)
    59% identity, 96% coverage of query (880 bits)

Q5M2Y4 formate C-acetyltransferase (EC 2.3.1.54) from Streptococcus thermophilus (see paper)
    44% identity, 99% coverage of query (639 bits)

pfl / Q59934 pyruvate formate-lyase subunit (EC 2.3.1.54) from Streptococcus mutans serotype c (strain ATCC 700610 / UA159) (see 2 papers)
    44% identity, 99% coverage of query (636 bits)

O66391 formate C-acetyltransferase (EC 2.3.1.54) from Streptococcus equinus (see paper)
    44% identity, 99% coverage of query (635 bits)

A0A0H2ZQE4 formate C-acetyltransferase (EC 2.3.1.54) from Streptococcus pneumoniae (see paper)
    43% identity, 100% coverage of query (627 bits)

pfl / CAA03991.1 pyruvate formate-lyase from Lactococcus lactis (see paper)
    44% identity, 100% coverage of query (624 bits)

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Build an alignment for 202036 and 12 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

1r9dA / Q8GEZ8 Glycerol bound form of the b12-independent glycerol dehydratase from clostridium butyricum (see paper)
    29% identity, 74% coverage of query (172 bits)

Q8GEZ8 glycerol dehydratase (EC 4.2.1.30) from Clostridium butyricum (see 2 papers)
    29% identity, 74% coverage of query (172 bits)

2f3oA / O28823 Crystal structure of a glycyl radical enzyme from archaeoglobus fulgidus (see paper)
    24% identity, 87% coverage of query (135 bits)

O28823 formate C-acetyltransferase (EC 2.3.1.54) from Archaeoglobus fulgidus (see paper)
    24% identity, 87% coverage of query (135 bits)

t4LhypD / Q180C6 trans-4-hydroxy-L-proline dehydratase (EC 4.2.1.172) from Clostridioides difficile (strain 630) (see paper)
    23% identity, 87% coverage of query (126 bits)

HYPD_CLODI / A0A031WDE4 Trans-4-hydroxy-L-proline dehydratase; Glycyl radical enzyme; Hyp dehydratase; EC 4.2.1.172 from Clostridioides difficile (Peptoclostridium difficile) (see paper)
6vxeA / A0A031WDE4 Crystal structure of hydroxyproline dehydratase (hypd) from clostridioides difficile with substrate trans-4-hydroxy-l-proline bound (see paper)
    23% identity, 87% coverage of query (125 bits)

masD / CAO03074.1 1-methyl alkyl succinate synthase subunit MasD from Azoarcus sp. HxN1 (see paper)
    22% identity, 74% coverage of query (100 bits)

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