Searching for up to 100 curated homologs for 202189 FitnessBrowser__MR1:202189 (376 a.a.)

Found high-coverage hits (≥70%) to 22 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

5dt9A / Q9KQ92 Crystal structure of a putative d-erythronate-4-phosphate dehydrogenase from vibrio cholerae
    51% identity, 99% coverage of query (360 bits)

3oetH / P60802 D-erythronate-4-phosphate dehydrogenase complexed with NAD
    46% identity, 99% coverage of query (314 bits)

Q7N2B2 4-phosphoerythronate dehydrogenase (EC 1.1.1.290) from Photorhabdus luminescens (see paper)
    47% identity, 99% coverage of query (301 bits)

PdxB / b2320 erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
pdxB / P05459 erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) from Escherichia coli (strain K12) (see 20 papers)
PDXB_ECOLI / P05459 Erythronate-4-phosphate dehydrogenase; EC 1.1.1.290 from Escherichia coli (strain K12) (see 2 papers)
P05459 4-phosphoerythronate dehydrogenase (EC 1.1.1.290) from Escherichia coli (see 3 papers)
    47% identity, 99% coverage of query (296 bits)

PDXB_PSEAE / Q9I3W9 Erythronate-4-phosphate dehydrogenase; EC 1.1.1.290 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
Q9I3W9 4-phosphoerythronate dehydrogenase (EC 1.1.1.290) from Pseudomonas aeruginosa (see paper)
2o4cA / Q9I3W9 Crystal structure of d-erythronate-4-phosphate dehydrogenase complexed with NAD (see paper)
    46% identity, 97% coverage of query (291 bits)

serA / GB|AAC83943.1 phosphoglycerate dehydrogenase; EC 1.1.1.95 from Bacillus subtilis (see paper)
serA / AAC83943.1 phosphoglycerate dehydrogenase from Bacillus subtilis (see 3 papers)
    30% identity, 75% coverage of query (115 bits)

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Build an alignment for 202189 and 6 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

SER33_YEAST / P40510 D-3-phosphoglycerate dehydrogenase 2; 3-PGDH 2; 2-oxoglutarate reductase; EC 1.1.1.95; EC 1.1.1.399 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
    27% identity, 81% coverage of query (109 bits)

Phgdh / O08651 3-phosphoglycerate dehydrogenase subunit (EC 1.1.1.95) from Rattus norvegicus (see paper)
SERA_RAT / O08651 D-3-phosphoglycerate dehydrogenase; 3-PGDH; EC 1.1.1.95 from Rattus norvegicus (Rat) (see paper)
O08651 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Rattus norvegicus (see paper)
    28% identity, 70% coverage of query (104 bits)

7dkmA / O43175 Phgdh covalently linked to oridonin (see paper)
    27% identity, 70% coverage of query (104 bits)

6plgA Crystal structure of human phgdh complexed with compound 15
    27% identity, 70% coverage of query (104 bits)

6cwaA Crystal structure phgdh in complex with nadh and 3-phosphoglycerate at 1.77 a resolution
    27% identity, 70% coverage of query (104 bits)

6rj3A Crystal structure of phgdh in complex with compound 15
    27% identity, 70% coverage of query (104 bits)

6plfA Crystal structure of human phgdh complexed with compound 1
    27% identity, 70% coverage of query (104 bits)

6rj5A Crystal structure of phgdh in complex with compound 39
    27% identity, 70% coverage of query (104 bits)

7ewhA Crystal structure of human phgdh in complex with homoharringtonine
    27% identity, 70% coverage of query (104 bits)

6rihA Crystal structure of phgdh in complex with compound 9
    27% identity, 70% coverage of query (104 bits)

P9WNX3 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Mycobacterium tuberculosis (see 5 papers)
    31% identity, 70% coverage of query (100 bits)

3dc2A / P9WNX3 Crystal structure of serine bound d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis (see paper)
    31% identity, 70% coverage of query (100 bits)

3ddnB Crystal structure of hydroxypyruvic acid phosphate bound d-3- phosphoglycerate dehydrogenase in mycobacterium tuberculosis
    31% identity, 70% coverage of query (100 bits)

6plfB Crystal structure of human phgdh complexed with compound 1
    27% identity, 70% coverage of query (95.5 bits)

Q9I6H5 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Pseudomonas aeruginosa (see paper)
    29% identity, 75% coverage of query (94.4 bits)

A4VGK3 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Pseudomonas stutzeri (see paper)
    27% identity, 82% coverage of query (91.7 bits)

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