Searching for up to 100 curated homologs for 202283 FitnessBrowser__MR1:202283 (309 a.a.)
Found high-coverage hits (≥70%) to 64 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
ORF35x7 / CAA69124.1 ORF35x7 from Vibrio cholerae (see paper)
52% identity, 97% coverage of query (306 bits)
wbpV / Q9RHC9 UDP-N-acetyl-α-D-quinovosamine dehydrogenase (EC 1.1.1.426) from Pseudomonas aeruginosa (see paper)
49% identity, 98% coverage of query (300 bits)
wreQ / Q6TP29 UDP-N-acetyl-α-D-quinovosamine dehydrogenase (EC 1.1.1.426) from Rhizobium etli (see 2 papers)
Q6TP29 UDP-N-acetyl-alpha-D-quinovosamine dehydrogenase (EC 1.1.1.426) from Rhizobium etli (see paper)
48% identity, 96% coverage of query (286 bits)
wbiG / GI|3135686 putative epimerase/dehydratase WbiG from Burkholderia pseudomallei (see paper)
36% identity, 98% coverage of query (196 bits)
wbpK / P72144 UDP-N-acetyl-α-D-fucosamine dehydrogenase from Pseudomonas aeruginosa (see 2 papers)
33% identity, 97% coverage of query (191 bits)
cpsG polysaccharide capsule synthesis protein CpsG from Streptococcus iniae (see paper)
31% identity, 79% coverage of query (107 bits)
Build an alignment for 202283 and 6 homologs with ≥ 30% identity
Or download the sequences
gnu / Q8X7P7 N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase (EC 5.1.3.26) from Escherichia coli O157:H7 (see 2 papers)
GNU_ECO57 / Q8X7P7 N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase; GlcNAc-P-P-Und 4-epimerase; EC 5.1.3.26 from Escherichia coli O157:H7 (see paper)
gne UDP-N-acetylglucosamine 4-epimerase; EC 5.1.3.7 from Escherichia coli O157:H7 (see paper)
27% identity, 99% coverage of query (92.8 bits)
NSDHL_MOUSE / Q9R1J0 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; EC 1.1.1.170 from Mus musculus (Mouse) (see 4 papers)
Q9R1J0 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) (EC 1.1.1.170) from Mus musculus (see paper)
26% identity, 81% coverage of query (73.2 bits)
ERG26_SCHPO / O43050 Sterol-4-alpha-carboxylate 3-dehydrogenase erg26, decarboxylating; C-3 sterol dehydrogenase erg26; C-4 decarboxylase erg26; Ergosterol biosynthetic protein 26; EC 1.1.1.170 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
26% identity, 98% coverage of query (72.4 bits)
6bwlA / Q3ESA4 X-ray structure of pal from bacillus thuringiensis (see paper)
25% identity, 97% coverage of query (70.5 bits)
3BHD_MYCNE / P0DX24 3-beta-hydroxysteroid dehydrogenase; 3beta-HSD; EC 1.1.1.51 from Mycolicibacterium neoaurum (Mycobacterium neoaurum) (see paper)
23% identity, 97% coverage of query (68.6 bits)
oleD / Q8PDW5 2-alkyl-3-oxo-fatty acid reductase monomer (EC 1.1.1.412) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see 2 papers)
OLED_XANCP / Q8PDW5 2-alkyl-3-oxoalkanoate reductase; EC 1.1.1.412 from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see 2 papers)
26% identity, 97% coverage of query (68.2 bits)
Q9WYX9 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Thermotoga maritima (see paper)
4zrnA / Q9WYX9 Crystal structure of udp-glucose 4-epimerase (tm0509) with udp-glucose from hyperthermophilic eubacterium thermotoga maritima (see paper)
25% identity, 97% coverage of query (65.9 bits)
YbjT / b0869 putative NAD(P)-dependent oxidoreductase YbjT from Escherichia coli K-12 substr. MG1655 (see paper)
24% identity, 100% coverage of query (65.5 bits)
RMLB_BACSU / P39630 dTDP-glucose 4,6-dehydratase; Spore coat polysaccharide biosynthesis protein SpsJ; EC 4.2.1.46 from Bacillus subtilis (strain 168) (see paper)
23% identity, 97% coverage of query (63.2 bits)
NSDHL / Q15738 NAD(P)-dependent 3β-hydroxy-4α-carboxy-sterol 3-dehydrogenase (decarboxylating) (EC 1.1.1.170) from Homo sapiens (see 5 papers)
NSDHL_HUMAN / Q15738 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Protein H105e3; EC 1.1.1.170 from Homo sapiens (Human) (see 4 papers)
Q15738 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) (EC 1.1.1.170) from Homo sapiens (see paper)
27% identity, 78% coverage of query (62.8 bits)
3β-HSD/D1 / Q9FX01 plant 3β-hydroxysteroid dehydrogenase/C4-decarboxylase 1 (EC 1.1.1.418) from Arabidopsis thaliana (see 3 papers)
HSDD1_ARATH / Q9FX01 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1; At3BETAHSD/D1; 4alpha-carboxysterol-C3-dehydrogenase/C4-decarboxylase isoform 1-1; Reticulon-like protein B24; AtRTNLB24; Sterol-4-alpha-carboxylate 3-dehydrogenase 1, decarboxylating; EC 1.1.1.418 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
22% identity, 91% coverage of query (62.4 bits)
RHM2 / Q9LPG6 trifunctional UDP-glucose 4,6-dehydratase/UDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase/UDP-4-dehydro-L-rhamnose-reductase RHM2 (EC 4.2.1.76) from Arabidopsis thaliana (see 2 papers)
RHM2_ARATH / Q9LPG6 Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM2; NDP-rhamnose synthase; Protein MUCILAGE-MODIFIED 4; Protein RHAMNOSE BIOSYNTHESIS 2; Rhamnose biosynthetic enzyme 2; AtRHM2; UDP-L-rhamnose synthase MUM4; EC 4.2.1.76; EC 1.1.1.-; EC 5.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
24% identity, 80% coverage of query (61.6 bits)
6zllA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-galacturonic acid and NAD (see paper)
26% identity, 78% coverage of query (60.8 bits)
OLED_STRMK / B2FI29 2-alkyl-3-oxoalkanoate reductase; EC 1.1.1.412 from Stenotrophomonas maltophilia (strain K279a) (see paper)
B2FI29 2-alkyl-3-oxoalkanoate reductase (EC 1.1.1.412) from Stenotrophomonas maltophilia (see 2 papers)
23% identity, 97% coverage of query (60.8 bits)
6zldA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-glucuronic acid and NAD
26% identity, 78% coverage of query (60.8 bits)
6zl6A Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp and NAD
26% identity, 78% coverage of query (60.8 bits)
TGDS_HUMAN / O95455 dTDP-D-glucose 4,6-dehydratase; EC 4.2.1.46 from Homo sapiens (Human) (see paper)
22% identity, 97% coverage of query (59.3 bits)
RHM3 / Q9LH76 trifunctional UDP-glucose 4,6-dehydratase/UDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase/UDP-4-dehydro-L-rhamnose-reductase RHM3 (EC 4.2.1.76) from Arabidopsis thaliana (see 2 papers)
RHM3_ARATH / Q9LH76 Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM3; Probable rhamnose biosynthetic enzyme 3; AtRHM3; EC 4.2.1.76; EC 1.1.1.-; EC 5.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
26% identity, 72% coverage of query (59.3 bits)
ERG26 / P53199 C-3 sterol dehydrogenase (EC 1.1.1.170) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 2 papers)
ERG26_YEAST / P53199 Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating; C-3 sterol dehydrogenase ERG26; C-4 decarboxylase ERG26; Ergosterol biosynthetic protein 26; EC 1.1.1.170 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 7 papers)
P53199 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) (EC 1.1.1.170) from Saccharomyces cerevisiae (see paper)
23% identity, 97% coverage of query (59.3 bits)
6zljA Crystal structure of udp-glucuronic acid 4-epimerase y149f mutant from bacillus cereus in complex with udp-4-deoxy-4-fluoro-glucuronic acid and NAD
25% identity, 78% coverage of query (59.3 bits)
ravE / D1H0J1 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) from Streptomyces ravidus (see 2 papers)
26% identity, 79% coverage of query (58.9 bits)
desIV / Q9ZGH3 dTDP-glucose 4,6-dehydratase monomer (EC 4.2.1.46) from Streptomyces venezuelae (see paper)
25% identity, 97% coverage of query (58.5 bits)
oleD / Q8EG63 hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oate reductase (EC 1.1.1.412) from Shewanella oneidensis (strain MR-1) (see paper)
OLED_SHEON / Q8EG63 2-alkyl-3-oxoalkanoate reductase; EC 1.1.1.412 from Shewanella oneidensis (strain MR-1) (see paper)
21% identity, 96% coverage of query (58.5 bits)
1r66A / Q9ZGH3 Crystal structure of desiv (dtdp-glucose 4,6-dehydratase) from streptomyces venezuelae with NAD and tyd bound (see paper)
25% identity, 97% coverage of query (58.5 bits)
1r6dA Crystal structure of desiv double mutant (dtdp-glucose 4,6- dehydratase) from streptomyces venezuelae with NAD and dau bound
27% identity, 78% coverage of query (58.5 bits)
6wj9B / Q4KCF6 Udp-glcnac c4-epimerase mutant s121a/y146f from pseudomonas protegens in complex with udp-glcnac (see paper)
27% identity, 70% coverage of query (58.2 bits)
6wjaA Udp-glcnac c4-epimerase mutant s121a/y146f from pseudomonas protegens in complex with udp-galnac
27% identity, 70% coverage of query (58.2 bits)
O73960 UDP-glucose 4-epimerase (EC 5.1.3.2) from Pyrococcus horikoshii (see paper)
21% identity, 97% coverage of query (56.6 bits)
2hunA / O58151 Crystal structure of hypothetical protein ph0414 from pyrococcus horikoshii ot3
21% identity, 98% coverage of query (56.6 bits)
3eheA / O29886 Crystal structure of udp-glucose 4 epimerase (gale-1) from archaeoglobus fulgidus
24% identity, 80% coverage of query (55.5 bits)
CERR_CAUVN / A0A0H3C8X7 Ceramide reductase; EC 1.-.-.- from Caulobacter vibrioides (strain NA1000 / CB15N) (Caulobacter crescentus) (see 2 papers)
24% identity, 84% coverage of query (55.5 bits)
gdh / Q93EK0 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) from Saccharopolyspora spinosa (see 2 papers)
23% identity, 96% coverage of query (54.3 bits)
mtmE / Q194R3 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) from Streptomyces argillaceus (see paper)
26% identity, 80% coverage of query (54.3 bits)
Q20697 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) from Caenorhabditis elegans (see paper)
23% identity, 97% coverage of query (53.9 bits)
RMLB_STRGR / P29782 dTDP-glucose 4,6-dehydratase; EC 4.2.1.46 from Streptomyces griseus (see paper)
25% identity, 79% coverage of query (53.9 bits)
3β-HSD/D2 / Q67ZE1 plant 3β-hydroxysteroid dehydrogenase/C4-decarboxylase 2 (EC 1.1.1.418) from Arabidopsis thaliana (see 3 papers)
HSDD2_ARATH / Q67ZE1 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2; At3BETAHSD/D2; 4alpha-carboxysterol-C3-dehydrogenase/C4-decarboxylase isoform 1-2; Reticulon-like protein B19; AtRTNLB19; Sterol-4-alpha-carboxylate 3-dehydrogenase 2, decarboxylating; EC 1.1.1.418 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
22% identity, 86% coverage of query (53.5 bits)
graE / AAA99939.1 dTDP-glucose dehydratase from Streptomyces violaceoruber (see paper)
23% identity, 96% coverage of query (53.5 bits)
hsdD / P9WQP7 3 β-hydroxysteroid dehydrogenase (EC 5.3.3.1; EC 1.1.1.145) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
3BHS_MYCTU / P9WQP7 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; Cholesterol dehydrogenase; EC 1.1.1.145; EC 5.3.3.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P9WQP7 3beta-hydroxy-DELTA5-steroid dehydrogenase (EC 1.1.1.145) from Mycobacterium tuberculosis (see paper)
22% identity, 97% coverage of query (52.8 bits)
P51107 dihydroflavonol 4-reductase (EC 1.1.1.219) from Solanum lycopersicum (see paper)
24% identity, 73% coverage of query (52.4 bits)
gdh / Q54116 dTDP-glucose 4,6-dehydratase monomer (EC 4.2.1.46) from Saccharopolyspora erythraea (see 2 papers)
24% identity, 96% coverage of query (52.0 bits)
agl12 / D4GU72 dTDP-glucose-4,6-dehydratase (EC 4.2.1.46) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 3 papers)
AGL12_HALVD / D4GU72 Low-salt glycan biosynthesis protein Agl12; EC 4.2.1.- from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
23% identity, 97% coverage of query (51.6 bits)
GME-1 / A3C4S4 GDP-mannose 3,5-epimerase 1 (EC 5.1.3.18) from Oryza sativa subsp. japonica (see paper)
GME1_ORYSJ / A3C4S4 GDP-mannose 3,5-epimerase 1; GDP-Man 3,5-epimerase 1; OsGME-1; EC 5.1.3.18 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
A3C4S4 GDP-mannose 3,5-epimerase (EC 5.1.3.18) from Oryza sativa (see paper)
24% identity, 96% coverage of query (51.6 bits)
GAL102 putative uncharacterized protein TGD99 from Candida albicans (see paper)
21% identity, 98% coverage of query (51.2 bits)
C6K2K9 GDP-mannose 3,5-epimerase (EC 5.1.3.18) from Solanum lycopersicum (see paper)
24% identity, 96% coverage of query (50.8 bits)
3BHS3_MESAU / O35296 NADPH-dependent 3-keto-steroid reductase HSD3B3; 3 beta-hydroxysteroid dehydrogenase type 3; 3 beta-hydroxysteroid dehydrogenase type III; 3 beta-HSD III; Dihydrotestosterone 3-ketoreductase; EC 1.1.1.270; EC 1.1.1.210 from Mesocricetus auratus (Golden hamster) (see paper)
24% identity, 81% coverage of query (50.4 bits)
Q9N119 3beta-hydroxy-DELTA5-steroid dehydrogenase (EC 1.1.1.145) from Sus scrofa (see 2 papers)
24% identity, 98% coverage of query (50.1 bits)
E9M5S1 GDP-mannose 3,5-epimerase (EC 5.1.3.18) from Citrus unshiu (see paper)
24% identity, 96% coverage of query (50.1 bits)
oleE / Q9RR28 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) from Streptomyces antibioticus (see paper)
OLEE_STRAT / Q9RR28 dTDP-glucose 4,6-dehydratase; EC 4.2.1.46 from Streptomyces antibioticus (see paper)
23% identity, 78% coverage of query (49.3 bits)
2c59A / Q93VR3 Gdp-mannose-3', 5' -epimerase (arabidopsis thaliana), with gdp-alpha- d-mannose and gdp-beta-l-galactose bound in the active site. (see paper)
23% identity, 96% coverage of query (47.8 bits)
GME / Q93VR3 GDP-D-mannose-3,5-epimerase (EC 5.1.3.18) from Arabidopsis thaliana (see paper)
GME_ARATH / Q93VR3 GDP-mannose 3,5-epimerase; GDP-Man 3,5-epimerase; EC 5.1.3.18 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
23% identity, 96% coverage of query (47.8 bits)
8sk0A Crystal structure of evds6 decarboxylase in ligand bound state
24% identity, 78% coverage of query (47.8 bits)
8sk0B / A0A1C5ADV9 Crystal structure of evds6 decarboxylase in ligand bound state (see paper)
24% identity, 78% coverage of query (47.4 bits)
2c54A Gdp-mannose-3', 5' -epimerase (arabidopsis thaliana),k178r, with gdp- beta-l-gulose and gdp-4-keto-beta-l-gulose bound in active site.
23% identity, 96% coverage of query (47.0 bits)
8vr2B / Q1QD53 Crystal structure of the pcryo_0617 oxidoreductase/decarboxylase from psychrobacter cryohalolentis k5 in the presence of NAD and udp
23% identity, 75% coverage of query (46.6 bits)
7k3pA / Q0P9C3 The structure of the udp-glc/glcnac 4-epimerase from the human pathogen campylobacter jejuni
23% identity, 94% coverage of query (46.2 bits)
8femA / A0A8T0SQV2 Panicum vigratum dihydroflavonol 4-reductase complexed with NADP (see paper)
25% identity, 70% coverage of query (46.2 bits)
8fenA Panicum vigratum dihydroflavonol 4-reductase complexed with NADP and dhq
25% identity, 70% coverage of query (46.2 bits)
6kvcA Moee5 in complex with udp-glucose and NAD
24% identity, 79% coverage of query (44.3 bits)
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Lawrence Berkeley National Laboratory