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Searching for up to 100 curated homologs for 203494 FitnessBrowser__MR1:203494 (447 a.a.)

Found high-coverage hits (≥70%) to 4 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

dcuB / CAA10331.1 C4-dicarboxylate membrane transporter from Wolinella succinogenes (see paper)
    55% identity, 99% coverage of query (482 bits)

GenF / b4123 anaerobic C4-dicarboxylate transporter DcuB from Escherichia coli K-12 substr. MG1655 (see 15 papers)
dcuB / P0ABN9 anaerobic C4-dicarboxylate transporter DcuB from Escherichia coli (strain K12) (see 16 papers)
DCUB_ECOLI / P0ABN9 Anaerobic C4-dicarboxylate transporter DcuB from Escherichia coli (strain K12) (see 9 papers)
TC 2.A.13.1.2 / P0ABN9 Anaerobic C4-dicarboxylate uptake/efflux porter, DcuB. Also catalyzes substrate:substrate antiport (fumarate:malate or fumarate:succinate antiport), but it is also a cosensor for the sensor kinase, DcuS (Kleefeld et al. 2009; Bauer et al. 2011; Chen et al. 2014) It has 12 established TMSs where the loop between TMSs 11 and 12 is the sensor. A central water-filled cavity may provide the transport pathway. The sensory domain of DcuB is composed of cytoplasmic loop XI/XII and a membrane integral region with the regulatory residues Thr396/Asp398 and Lys353. Also transports D-tartrate from Escherichia coli (see 7 papers)
    56% identity, 91% coverage of query (443 bits)

fraA / Q8ZLD2 N-(1-deoxy-D-fructos-1-yl)-L-aspartate transporter from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
TC 2.A.13.1.3 / Q8ZLD2 C4-dicarboxylate transporter, YhiT from Salmonella typhimurium (see paper)
    41% identity, 100% coverage of query (321 bits)

GenA / b4138 C4-dicarboxylate transporter DcuA from Escherichia coli K-12 substr. MG1655 (see 9 papers)
dcuA / P0ABN5 C4-dicarboxylate transporter DcuA from Escherichia coli (strain K12) (see 12 papers)
DCUA_ECOLI / P0ABN5 C4-dicarboxylate transporter DcuA from Escherichia coli (strain K12) (see 7 papers)
TC 2.A.13.1.1 / P0ABN5 Anaerobic C4-dicarboxylate antiporter (aspartate:fumarate antiporter) from Escherichia coli (see 10 papers)
    38% identity, 100% coverage of query (273 bits)

Build an alignment

Build an alignment for 203494 and 4 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory