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Searching for up to 100 curated homologs for 203782 FitnessBrowser__MR1:203782 (452 a.a.)

Found high-coverage hits (≥70%) to 11 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

3bznA / P38051 Crystal structure of open form of menaquinone-specific isochorismate synthase, menf (see paper)
    35% identity, 99% coverage of query (233 bits)

YfbA / b2265 isochorismate synthase MenF (EC 5.4.4.2) from Escherichia coli K-12 substr. MG1655 (see paper)
menF / P38051 isochorismate synthase MenF (EC 5.4.4.2) from Escherichia coli (strain K12) (see 8 papers)
MENF_ECOLI / P38051 Isochorismate synthase MenF; Isochorismate hydroxymutase; Isochorismate mutase; EC 5.4.4.2 from Escherichia coli (strain K12) (see 6 papers)
P38051 isochorismate synthase (EC 5.4.4.2) from Escherichia coli (see 3 papers)
    35% identity, 99% coverage of query (233 bits)

ICS_CATRO / Q9ZPC0 Isochorismate synthase, chloroplastic; EC 5.4.4.2 from Catharanthus roseus (Madagascar periwinkle) (Vinca rosea) (see 3 papers)
    32% identity, 95% coverage of query (213 bits)

8w6vA / Q9S7H8 Structural basis of chorismate isomerization by arabidopsis isochorismate synthase ics1 (see paper)
    33% identity, 90% coverage of query (198 bits)

8w71A Structural basis of chorismate isomerization by arabidopsis isochorismate synthase ics1
    33% identity, 90% coverage of query (198 bits)

ICS1_ARATH / Q9S7H8 Isochorismate synthase 1, chloroplastic; AtIcs1; IcsI; Enhanced disease susceptibility 16; Eds16; Isochorismate mutase 1; Salicylic acid induction deficient 2; Sid2; menF-like protein 1; EC 5.4.4.2 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q9S7H8 isochorismate synthase (EC 5.4.4.2) from Arabidopsis thaliana (see 6 papers)
    35% identity, 78% coverage of query (196 bits)

ICS2_ARATH / Q9M9V6 Isochorismate synthase 2, chloroplastic; AtIcs2; Isochorismate mutase 2; menF-like protein 2; EC 5.4.4.2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9M9V6 isochorismate synthase (EC 5.4.4.2) from Arabidopsis thaliana (see 2 papers)
    34% identity, 79% coverage of query (191 bits)

pchA / Q51508 isochorismate synthase (EC 5.4.4.2) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
PCHA_PSEAE / Q51508 Salicylate biosynthesis isochorismate synthase; Isochorismate mutase; EC 5.4.4.2 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    32% identity, 82% coverage of query (173 bits)

Build an alignment

Build an alignment for 203782 and 8 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

menF / P23973 isochorismate synthase monomer (EC 5.4.4.2) from Bacillus subtilis (strain 168) (see paper)
    28% identity, 91% coverage of query (166 bits)

para-aminobenzoate synthase component I / b1812 aminodeoxychorismate synthase subunit 1 (EC 2.6.1.85) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
pabB / P05041 aminodeoxychorismate synthase subunit 1 (EC 2.6.1.85) from Escherichia coli (strain K12) (see 17 papers)
PABB_ECOLI / P05041 Aminodeoxychorismate synthase component 1; ADC synthase; ADCS; 4-amino-4-deoxychorismate synthase component 1; EC 2.6.1.85 from Escherichia coli (strain K12) (see 8 papers)
pabB / RF|NP_416326.1 para-aminobenzoate synthase, component 1; EC 2.6.1.85 from Escherichia coli K12 (see 8 papers)
    26% identity, 78% coverage of query (71.2 bits)

1k0eA / P05041 The crystal structure of aminodeoxychorismate synthase from formate grown crystals (see paper)
    25% identity, 78% coverage of query (64.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory