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Searching for up to 100 curated homologs for 207344 MicrobesOnline__882:207344 (340 a.a.)

Found high-coverage hits (≥70%) to 26 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AO353_07670 L-threonine aldolase (EC 4.1.2.5) from Pseudomonas fluorescens FW300-N2E3
    45% identity, 99% coverage of query (296 bits)

5vyeB / A0A166JNM8 Crystal structure of l-threonine aldolase from pseudomonas putida
    46% identity, 99% coverage of query (293 bits)

PfGW456L13_1114 L-threonine aldolase (EC 4.1.2.5) from Pseudomonas fluorescens GW456-L13
    45% identity, 99% coverage of query (290 bits)

Q88R13 L-threonine aldolase (EC 4.1.2.5) from Pseudomonas putida (see paper)
    46% identity, 99% coverage of query (290 bits)

O50584 low-specificity L-threonine aldolase (EC 4.1.2.48) from Pseudomonas sp. (see paper)
    45% identity, 99% coverage of query (289 bits)

O50584 Low specificity L-threonine aldolase; Low specificity L-TA; EC 4.1.2.48 from Pseudomonas sp. (strain NCIMB 10558)
    45% identity, 99% coverage of query (289 bits)

1v72A / Q59IT3 Crystal structure of phenylserine aldolase from pseudomonas putida
    41% identity, 98% coverage of query (229 bits)

Q59IT3 phenylserine aldolase (EC 4.1.2.26) from Pseudomonas putida (see paper)
GI|62084361 phenylserine aldolase; EC 4.1.2.26 from Pseudomonas putida (see paper)
    41% identity, 98% coverage of query (229 bits)

A0T1V9 low-specificity L-threonine aldolase (EC 4.1.2.48) from Sinorhizobium arboris (see paper)
    39% identity, 98% coverage of query (220 bits)

Build an alignment

Build an alignment for 207344 and 9 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

orf19.6305 hydroxytrimethyllysine aldolase from Candida albicans (see paper)
    25% identity, 98% coverage of query (69.7 bits)

GLY1 / GB|AAA72430.1 threonine aldolase; EC 4.1.2.5 from Saccharomyces cerevisiae (see paper)
    27% identity, 70% coverage of query (57.8 bits)

GLY1 / P37303 L-threonine aldolase subunit (EC 4.1.2.48) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
GLY1_YEAST / P37303 Low specificity L-threonine aldolase; Low specificity L-TA; TA; EC 4.1.2.48 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P37303 low-specificity L-threonine aldolase (EC 4.1.2.48) from Saccharomyces cerevisiae (see paper)
    25% identity, 70% coverage of query (56.2 bits)

1jg8D / Q9X266 Crystal structure of threonine aldolase (low-specificity)
    24% identity, 86% coverage of query (56.2 bits)

Q9X266 L-threonine aldolase (EC 4.1.2.5) from Thermotoga maritima (see paper)
    24% identity, 84% coverage of query (54.7 bits)

1lw5B X-ray structure of l-threonine aldolase (low-specificity) in complex with glycine
    24% identity, 84% coverage of query (54.7 bits)

1lw4B X-ray structure of l-threonine aldolase (low-specificity) in complex with l-allo-threonine
    24% identity, 84% coverage of query (54.7 bits)

THA2_ARATH / Q9FPH3 Probable low-specificity L-threonine aldolase 2; Threonine aldolase 2; EC 4.1.2.48 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    26% identity, 70% coverage of query (52.8 bits)

LtaA / b0870 low-specificity L-threonine aldolase (EC 4.1.2.48; EC 4.1.2.5; EC 4.1.2.26; EC 4.1.2.49) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ltaE / P75823 low-specificity L-threonine aldolase (EC 4.1.2.48; EC 4.1.2.26) from Escherichia coli (strain K12) (see 4 papers)
LTAE_ECOLI / P75823 Low specificity L-threonine aldolase; Low specificity L-TA; EC 4.1.2.48 from Escherichia coli (strain K12) (see paper)
P75823 low-specificity L-threonine aldolase (EC 4.1.2.48) from Escherichia coli (see 2 papers)
itaE / GB|BAA20882.1 threonine aldolase; EC 4.1.2.5 from Escherichia coli K12 (see 4 papers)
    25% identity, 93% coverage of query (52.4 bits)

3wlxA Crystal structure of low-specificity l-threonine aldolase from escherichia coli
    25% identity, 93% coverage of query (52.4 bits)

ltaA / O07051 L-allo-threonine aldolase subunit (EC 4.1.2.48) from Aeromonas jandaei (see paper)
LTAA_AERJA / O07051 L-allo-threonine aldolase; L-allo-TA; L-allo-threonine acetaldehyde-lyase; EC 4.1.2.49 from Aeromonas jandaei (see 2 papers)
O07051 L-allo-threonine aldolase (EC 4.1.2.49) from Aeromonas jandaei (see 4 papers)
ltaA / GB|BAA20404.1 L-allo-threonine aldolase; EC 4.1.2.- from Aeromonas jandaei (see 2 papers)
    24% identity, 99% coverage of query (50.1 bits)

4lnjA Structure of escherichia coli threonine aldolase in unliganded form (see paper)
    24% identity, 93% coverage of query (48.1 bits)

3wgcB / O07051 Aeromonas jandaei l-allo-threonine aldolase h128y/s292r double mutant (see paper)
    24% identity, 99% coverage of query (48.1 bits)

4rjyA Crystal structure of e. Coli l-threonine aldolase in complex with a non-covalently uncleaved bound l-serine substrate
    24% identity, 93% coverage of query (48.1 bits)

4lnlA Structure of escherichia coli threonine aldolase in complex with allo- thr
    24% identity, 93% coverage of query (48.1 bits)

4lnmA Structure of escherichia coli threonine aldolase in complex with serine
    24% identity, 93% coverage of query (48.1 bits)

THA1_ARATH / Q8RXU4 Low-specificity L-threonine aldolase 1; Threonine aldolase 1; EC 4.1.2.48 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    25% identity, 78% coverage of query (43.9 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory