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Searching for up to 100 curated homologs for 208172 MicrobesOnline__882:208172 (389 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

GLPA1_HALVD / D4GYI2 Anaerobic glycerol-3-phosphate dehydrogenase subunit A1; G-3-P dehydrogenase A1; G3PDH A1; EC 1.1.5.3 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
    41% identity, 94% coverage of query (266 bits)

GLPA2_HALVD / D4GQU6 Anaerobic glycerol-3-phosphate dehydrogenase subunit A2; G-3-P dehydrogenase A2; G3PDH A2; EC 1.1.5.3 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
    40% identity, 93% coverage of query (253 bits)

GlpA / b2241 anaerobic glycerol-3-phosphate dehydrogenase subunit A (EC 1.1.5.3) from Escherichia coli K-12 substr. MG1655 (see 10 papers)
glpA / P0A9C0 anaerobic glycerol-3-phosphate dehydrogenase subunit A (EC 1.1.5.3) from Escherichia coli (strain K12) (see 8 papers)
    38% identity, 92% coverage of query (242 bits)

Build an alignment

Build an alignment for 208172 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

GPD2 / P43304 mitochondrial glycerol-3-phosphate dehydrogenase subunit (EC 1.1.5.3) from Homo sapiens (see 8 papers)
GPDM_HUMAN / P43304 Glycerol-3-phosphate dehydrogenase, mitochondrial; GPD-M; GPDH-M; mitohondrial glycerophosphate dehydrogenase gene; mGDH; mtGPD; EC 1.1.5.3 from Homo sapiens (Human) (see paper)
P43304 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Homo sapiens (see 2 papers)
    28% identity, 96% coverage of query (112 bits)

Q64521 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Mus musculus (see 3 papers)
    28% identity, 92% coverage of query (100 bits)

P35571 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Rattus norvegicus (see 4 papers)
    28% identity, 92% coverage of query (99.4 bits)

AT3g10370 / Q9SS48 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Arabidopsis thaliana (see paper)
SDP6_ARATH / Q9SS48 Glycerol-3-phosphate dehydrogenase SDP6, mitochondrial; Protein SUGAR-DEPENDENT 6; EC 1.1.5.3 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    28% identity, 97% coverage of query (90.5 bits)

GUT2 glycerol-3-phosphate dehydrogenase, mitochondrial from Candida albicans (see paper)
    23% identity, 96% coverage of query (82.0 bits)

Q06B39 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Dunaliella salina (see paper)
    25% identity, 93% coverage of query (80.5 bits)

GUT2 / P32191 glycerol-3-phosphate dehydrogenase (EC 1.1.1.8; EC 1.1.1.94; EC 1.1.5.3) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 23 papers)
GPDM_YEAST / P32191 Glycerol-3-phosphate dehydrogenase, mitochondrial; GPD-M; GPDH-M; EC 1.1.5.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
    24% identity, 93% coverage of query (74.3 bits)

GPDH_ENCCU / Q8SR40 Probable glycerol-3-phosphate dehydrogenase; GPDH; EC 1.1.5.3 from Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite) (see paper)
    22% identity, 97% coverage of query (71.2 bits)

Q8U022 proline dehydrogenase (EC 1.5.5.2) from Pyrococcus furiosus (see paper)
    25% identity, 71% coverage of query (69.7 bits)

O59445 proline dehydrogenase (EC 1.5.5.2) from Pyrococcus horikoshii (see paper)
    25% identity, 71% coverage of query (61.6 bits)

L2HDH_ACCRE / A0A011QK89 L-2-hydroxyglutarate dehydrogenase; EC 1.1.99.2 from Accumulibacter regalis (see paper)
    27% identity, 81% coverage of query (54.3 bits)

2rgoA / D0VWP7 Structure of alpha-glycerophosphate oxidase from streptococcus sp.: A template for the mitochondrial alpha-glycerophosphate dehydrogenase (see paper)
    21% identity, 85% coverage of query (50.1 bits)

4yshA / Q5L2C2 Crystal structure of glycine oxidase from geobacillus kaustophilus
    24% identity, 75% coverage of query (49.3 bits)

4yshB Crystal structure of glycine oxidase from geobacillus kaustophilus
    24% identity, 75% coverage of query (49.3 bits)

GLYOX_GEOKA / Q5L2C2 Glycine oxidase; GO; GOX; GOXK; EC 1.4.3.19 from Geobacillus kaustophilus (strain HTA426) (see paper)
Q5L2C2 glycine oxidase (EC 1.4.3.19) from Geobacillus kaustophilus (see paper)
    24% identity, 75% coverage of query (46.6 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory