Searching for up to 100 curated homologs for 208271 MicrobesOnline__882:208271 (208 a.a.)
Found high-coverage hits (≥70%) to 45 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
7ev5A / A0A060M4R1 Crystal structure of bleg-1 b3 metallo-beta-lactamase (see paper)
37% identity, 96% coverage of query (125 bits)
2zwrB / Q5SHV7 Crystal structure of ttha1623 from thermus thermophilus hb8 (see paper)
37% identity, 97% coverage of query (121 bits)
7l0bA Crystal structure of hydroxyacyl glutathione hydrolase (glob) from staphylococcus aureus, apoenzyme (see paper)
36% identity, 96% coverage of query (119 bits)
2zziA Crystal structure of ttha1623 in a di-iron-bound form
38% identity, 94% coverage of query (119 bits)
A0A0D1GCF8 hydroxyacylglutathione hydrolase (EC 3.1.2.6) from Staphylococcus aureus (see paper)
35% identity, 96% coverage of query (115 bits)
GloC / b0927 hydroxyacylglutathione hydrolase GloC (EC 3.1.2.6) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
gloC / P75849 hydroxyacylglutathione hydrolase GloC (EC 3.1.2.6) from Escherichia coli (strain K12) (see 5 papers)
GLO22_ECOLI / P75849 Hydroxyacylglutathione hydrolase GloC; Accessory type II glyoxalase; Glyoxalase II 2; GlxII-2; EC 3.1.2.6 from Escherichia coli (strain K12) (see paper)
33% identity, 99% coverage of query (112 bits)
2xf4A Crystal structure of salmonella enterica serovar typhimurium ycbl (see paper)
31% identity, 99% coverage of query (108 bits)
Y554_STRP6 / Q5XD24 Probable metallo-hydrolase M6_Spy0554; EC 3.-.-.- from Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)
30% identity, 91% coverage of query (105 bits)
4ysbA / Q1D4C9 Crystal structure of ethe1 from myxococcus xanthus (see paper)
34% identity, 87% coverage of query (91.7 bits)
sdo / B7J413 sulfur dioxygenase α subunit (EC 1.13.11.18) from Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455) (see 4 papers)
B7J413 persulfide dioxygenase (EC 1.13.11.18) from Acidithiobacillus ferrooxidans (see paper)
36% identity, 85% coverage of query (89.4 bits)
ETHE1 / O95571 mitochondrial persulfide dioxygenase monomer (EC 1.13.11.18) from Homo sapiens (see 6 papers)
ETHE1_HUMAN / O95571 Persulfide dioxygenase ETHE1, mitochondrial; Ethylmalonic encephalopathy protein 1; Hepatoma subtracted clone one protein; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Homo sapiens (Human) (see 6 papers)
34% identity, 89% coverage of query (86.3 bits)
4chlB / O95571 Human ethylmalonic encephalopathy protein 1 (hethe1) (see paper)
35% identity, 88% coverage of query (85.9 bits)
ETHE1_MOUSE / Q9DCM0 Persulfide dioxygenase ETHE1, mitochondrial; Ethylmalonic encephalopathy protein 1 homolog; Hepatoma subtracted clone one protein; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Mus musculus (Mouse) (see paper)
32% identity, 88% coverage of query (82.8 bits)
5ve5A / B2TEQ2 Crystal structure of persulfide dioxygenase rhodanese fusion protein with rhodanese domain inactivating mutation (c314s) from burkholderia phytofirmans in complex with glutathione (see paper)
33% identity, 88% coverage of query (81.3 bits)
Q940L0 hydroxyacylglutathione hydrolase (EC 3.1.2.6) from Oryza sativa (see 3 papers)
35% identity, 79% coverage of query (79.7 bits)
GLO2M_ARATH / O24495 Hydroxyacylglutathione hydrolase 1, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
36% identity, 83% coverage of query (79.7 bits)
2gcuA / Q9C8L4 X-ray structure of gene product from arabidopsis thaliana at1g53580 (see paper)
31% identity, 88% coverage of query (77.4 bits)
ETHE1_ARATH / Q9C8L4 Persulfide dioxygenase ETHE1 homolog, mitochondrial; Glyoxalase II; Glx II; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9C8L4 persulfide dioxygenase (EC 1.13.11.18) from Arabidopsis thaliana (see paper)
31% identity, 88% coverage of query (77.0 bits)
2q42A / Q9SID3 Ensemble refinement of the protein crystal structure of glyoxalase ii from arabidopsis thaliana gene at2g31350 (see paper)
34% identity, 90% coverage of query (74.7 bits)
GLO2N_ARATH / Q9SID3 Hydroxyacylglutathione hydrolase 2, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
35% identity, 79% coverage of query (74.7 bits)
BLH_AGRFC / Q8UAA9 Beta-lactamase hydrolase-like protein; BLH; EC 3.-.-.- from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
31% identity, 81% coverage of query (68.2 bits)
Build an alignment for 208271 and 21 homologs with ≥ 30% identity
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BLH_XYLFA / Q9PFB0 Beta-lactamase hydrolase-like protein; BLH; EC 3.-.-.- from Xylella fastidiosa (strain 9a5c) (see paper)
29% identity, 81% coverage of query (65.9 bits)
PKSB_BACSU / O34769 Probable polyketide biosynthesis zinc-dependent hydrolase PksB; EC 3.-.-.- from Bacillus subtilis (strain 168) (see 2 papers)
25% identity, 97% coverage of query (64.7 bits)
blhA / CBY83975.1 metallo-beta-lactamase family from Serratia sp. ATCC 39006 (see paper)
32% identity, 73% coverage of query (64.7 bits)
4yskA / A5VWI3 Crystal structure of apo-form sdoa from pseudomonas putida (see paper)
32% identity, 81% coverage of query (64.3 bits)
4yslA Crystal structure of sdoa from pseudomonas putida in complex with glutathione
32% identity, 81% coverage of query (64.3 bits)
3r2uB 2.1 angstrom resolution crystal structure of metallo-beta-lactamase from staphylococcus aureus subsp. Aureus col
27% identity, 93% coverage of query (63.5 bits)
GLO2 / Q05584 glyoxalase II (cytoplasmic) (EC 3.1.2.6) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 2 papers)
GLO2_YEAST / Q05584 Hydroxyacylglutathione hydrolase, cytoplasmic isozyme; Glyoxalase II; Glx II; EC 3.1.2.6 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
GLO2 / CAA71335.1 glyoxalase-II from Saccharomyces cerevisiae (see paper)
28% identity, 83% coverage of query (62.8 bits)
A0A1E7YQH3 persulfide dioxygenase (EC 1.13.11.18) from Acidithiobacillus caldus (see paper)
27% identity, 87% coverage of query (57.8 bits)
G5ELA4 persulfide dioxygenase (EC 1.13.11.18) from Staphylococcus aureus (see paper)
27% identity, 99% coverage of query (57.0 bits)
4efzA / Q3JRV4 Crystal structure of a hypothetical metallo-beta-lactamase from burkholderia pseudomallei
32% identity, 75% coverage of query (56.6 bits)
BAEB_BACVZ / A7Z4X7 Probable polyketide biosynthesis zinc-dependent hydrolase BaeB; EC 3.-.-.- from Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42) (Bacillus amyloliquefaciens subsp. plantarum) (see paper)
24% identity, 97% coverage of query (55.1 bits)
3r2uA / A0A0H2X0Y8 2.1 angstrom resolution crystal structure of metallo-beta-lactamase from staphylococcus aureus subsp. Aureus col
25% identity, 92% coverage of query (54.7 bits)
3tp9A / C8WS08 Crystal structure of alicyclobacillus acidocaldarius protein with beta-lactamase and rhodanese domains
27% identity, 81% coverage of query (52.8 bits)
GLO22_SCHPO / O94250 Probable hydroxyacylglutathione hydrolase C13B11.03c; Glyoxalase II; Glx II; EC 3.1.2.6 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
27% identity, 82% coverage of query (49.7 bits)
PKGB_EMENI / Q5AXB0 Thioesterase pkgB; Pkg biosynthesis cluster protein B; EC 3.1.2.- from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
30% identity, 86% coverage of query (48.5 bits)
1qh3A / Q16775 Human glyoxalase ii with cacodylate and acetate ions present in the active site (see paper)
25% identity, 80% coverage of query (48.5 bits)
1qh5B Human glyoxalase ii with s-(n-hydroxy-n-bromophenylcarbamoyl) glutathione
25% identity, 80% coverage of query (48.5 bits)
1qh5A Human glyoxalase ii with s-(n-hydroxy-n-bromophenylcarbamoyl) glutathione
25% identity, 80% coverage of query (48.5 bits)
GLO2_HUMAN / Q16775 Hydroxyacylglutathione hydrolase, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Homo sapiens (Human) (see 3 papers)
Q16775 hydroxyacylglutathione hydrolase (EC 3.1.2.6) from Homo sapiens (see 8 papers)
25% identity, 80% coverage of query (48.1 bits)
GLO2_RAT / O35952 Hydroxyacylglutathione hydrolase, mitochondrial; Glyoxalase II; Glx II; Round spermatid protein RSP29; EC 3.1.2.6 from Rattus norvegicus (Rat) (see 2 papers)
O35952 hydroxyacylglutathione hydrolase (EC 3.1.2.6) from Rattus norvegicus (see paper)
24% identity, 80% coverage of query (48.1 bits)
2p18A / Q2PYN0 Crystal structure of the leishmania infantum glyoxalase ii (see paper)
29% identity, 81% coverage of query (47.4 bits)
GLO4 / Q12320 hydroxyacylglutathione hydrolase (EC 3.1.2.6) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 6 papers)
Q12320 hydroxyacylglutathione hydrolase (EC 3.1.2.6) from Saccharomyces cerevisiae (see paper)
GLO4 / CAA58065.1 glyoxalase-II from Saccharomyces cerevisiae (see 3 papers)
28% identity, 80% coverage of query (47.4 bits)
8ewoA / Q9I2T1 Crystal structure of putative glyoxylase ii from pseudomonas aeruginosa
34% identity, 80% coverage of query (47.0 bits)
GLO2C_ARATH / O24496 Hydroxyacylglutathione hydrolase cytoplasmic; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
29% identity, 79% coverage of query (46.2 bits)
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Lawrence Berkeley National Laboratory