Searching for up to 100 curated homologs for 208445 MicrobesOnline__882:208445 (250 a.a.)
Found high-coverage hits (≥70%) to 59 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q54NE6 2,3-bisphosphoglycerate 3-phosphatase (EC 3.1.3.80) from Dictyostelium discoideum (see paper)
52% identity, 98% coverage of query (280 bits)
PGAM1_CHICK / Q5ZLN1 Phosphoglycerate mutase 1; BPG-dependent PGAM 1; EC 5.4.2.11; EC 5.4.2.4 from Gallus gallus (Chicken) (see paper)
53% identity, 99% coverage of query (279 bits)
3gp5A / Q3JWH7 Crystal structure of phosphoglyceromutase from burkholderia pseudomallei with 3-phosphoglyceric acid and vanadate (see paper)
57% identity, 92% coverage of query (278 bits)
GPMA_BURP1 / Q3JWH7 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM; EC 5.4.2.11 from Burkholderia pseudomallei (strain 1710b) (see paper)
Q3JWH7 phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) (EC 5.4.2.11) from Burkholderia pseudomallei (see paper)
57% identity, 92% coverage of query (278 bits)
3fdzA Crystal structure of phosphoglyceromutase from burkholderia pseudomallei 1710b with bound 2,3-diphosphoglyceric acid and 3- phosphoglyceric acid
57% identity, 92% coverage of query (277 bits)
3gp3A Crystal structure of phosphoglyceromutase from burkholderia pseudomallei with 2-phosphoserine
56% identity, 92% coverage of query (275 bits)
B5KJG2 phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) (EC 5.4.2.11) from Sus scrofa (see paper)
52% identity, 98% coverage of query (271 bits)
Gpm / b0755 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (EC 5.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
gpmA / P62707 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (EC 5.4.2.11) from Escherichia coli (strain K12) (see 20 papers)
GPMA_ECOLI / P62707 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM; EC 5.4.2.11 from Escherichia coli (strain K12) (see 4 papers)
gpmA / PDB|1E58_A 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; EC 5.4.2.1 from Shigella flexneri (see 12 papers)
52% identity, 98% coverage of query (270 bits)
1e59A / P62707 E.Coli cofactor-dependent phosphoglycerate mutase complexed with vanadate (see paper)
52% identity, 95% coverage of query (268 bits)
PGM / AAA26800.1 phosphoglycerate mutase from Streptomyces coelicolor (see paper)
55% identity, 98% coverage of query (268 bits)
PGAM2 / P15259 phosphoglycerate mutase 2 (EC 5.4.2.4; EC 5.4.2.11) from Homo sapiens (see 3 papers)
PGAM2_HUMAN / P15259 Phosphoglycerate mutase 2; BPG-dependent PGAM 2; Muscle-specific phosphoglycerate mutase; Phosphoglycerate mutase isozyme M; PGAM-M; EC 5.4.2.11; EC 5.4.2.4 from Homo sapiens (Human) (see 3 papers)
P15259 phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) (EC 5.4.2.11) from Homo sapiens (see paper)
50% identity, 98% coverage of query (266 bits)
Q9DBJ1 phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) (EC 5.4.2.11) from Mus musculus (see paper)
54% identity, 99% coverage of query (266 bits)
PGAM2_MOUSE / O70250 Phosphoglycerate mutase 2; BPG-dependent PGAM 2; Muscle-specific phosphoglycerate mutase; Phosphoglycerate mutase isozyme M; PGAM-M; EC 5.4.2.11; EC 5.4.2.4 from Mus musculus (Mouse) (see 2 papers)
O70250 phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) (EC 5.4.2.11) from Mus musculus (see paper)
51% identity, 98% coverage of query (266 bits)
PGAM1 / P18669 phosphoglycerate mutase 1 (EC 5.4.2.4; EC 5.4.2.11) from Homo sapiens (see 6 papers)
PGAM1_HUMAN / P18669 Phosphoglycerate mutase 1; BPG-dependent PGAM 1; Phosphoglycerate mutase isozyme B; PGAM-B; EC 5.4.2.11; EC 5.4.2.4 from Homo sapiens (Human) (see 4 papers)
P18669 phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) (EC 5.4.2.11) from Homo sapiens (see 5 papers)
54% identity, 99% coverage of query (265 bits)
7xb8B / P18669 Phosphoglycerate mutase 1 complexed with a covalent inhibitor
54% identity, 98% coverage of query (264 bits)
PMGY_CANAL / P82612 Phosphoglycerate mutase; PGAM; BPG-dependent PGAM; MPGM; Phosphoglyceromutase; EC 5.4.2.11 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see paper)
GPM1 phosphoglycerate mutase; EC 5.4.2.1 from Candida albicans (see 6 papers)
54% identity, 98% coverage of query (263 bits)
7xb7B Phosphoglycerate mutase 1 complexed with a covalent inhibitor
54% identity, 96% coverage of query (258 bits)
1yfkA Crystal structure of human b type phosphoglycerate mutase
55% identity, 91% coverage of query (254 bits)
5y35C Phosphoglycerate mutase 1 complexed with a small molecule inhibitor kh1
55% identity, 91% coverage of query (254 bits)
5y65C Phosphoglycerate mutase 1 complexed with a small molecule inhibitor kh2
55% identity, 91% coverage of query (254 bits)
5y2uB X-ray structure of phosphoglycerate mutase 1(pgam1) complexed with a small molecule
55% identity, 91% coverage of query (253 bits)
5zs8C Acetylation of lysine 100 of phosphoglycerate mutase 1 complexed with kh_ol
55% identity, 91% coverage of query (253 bits)
5y2iB Phosphoglycerate mutase 1 (pgam1) complexed with its inhibitor pgmi- 004a
55% identity, 91% coverage of query (253 bits)
6isnC Phosphoglycerate mutase 1 complexed with a small molecule inhibitor
55% identity, 91% coverage of query (253 bits)
5zrmC Phosphoglycerate mutase 1 complexed with a small molecule inhibitor in-ac
55% identity, 91% coverage of query (253 bits)
7xb9B Phosphoglycerate mutase 1 complexed with a covalent inhibitor
56% identity, 89% coverage of query (250 bits)
GPM1 / P00950 phosphoglycerate mutase (EC 5.4.2.11) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
PMG1_YEAST / P00950 Phosphoglycerate mutase 1; PGAM 1; BPG-dependent PGAM 1; MPGM 1; Phosphoglyceromutase 1; EC 5.4.2.11 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 12 papers)
50% identity, 98% coverage of query (248 bits)
5pgmE Saccharomyces cerevisiae phosphoglycerate mutase
50% identity, 93% coverage of query (245 bits)
1bq4A Saccharomyces cerevisiae phosphoglycerate mutase in complex with benzene hexacarboxylate
50% identity, 93% coverage of query (245 bits)
1bq3A Saccharomyces cerevisiae phosphoglycerate mutase in complex with inositol hexakisphosphate
50% identity, 93% coverage of query (245 bits)
1qhfA / P00950 Yeast phosphoglycerate mutase-3pg complex structure to 1.7 a (see paper)
51% identity, 92% coverage of query (244 bits)
GPMA_STRP6 / Q5XB88 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM; EC 5.4.2.11 from Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)
49% identity, 92% coverage of query (242 bits)
GPMA_MYCTU / P9WIC9 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM; EC 5.4.2.11 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
55% identity, 88% coverage of query (234 bits)
PMGE_RABIT / P07952 Bisphosphoglycerate mutase; BPGM; 2,3-bisphosphoglycerate mutase, erythrocyte; 2,3-bisphosphoglycerate synthase; BPG-dependent PGAM; EC 5.4.2.4; EC 5.4.2.11 from Oryctolagus cuniculus (Rabbit) (see paper)
46% identity, 99% coverage of query (228 bits)
BPGM / P07738 Bisphosphoglycerate mutase (EC 5.4.2.11; EC 5.4.2.4) from Homo sapiens (see 5 papers)
PMGE_HUMAN / P07738 Bisphosphoglycerate mutase; BPGM; 2,3-bisphosphoglycerate mutase, erythrocyte; 2,3-bisphosphoglycerate synthase; 2,3-diphosphoglycerate mutase; DPGM; BPG-dependent PGAM; EC 5.4.2.4; EC 5.4.2.11 from Homo sapiens (Human) (see 10 papers)
P07738 Bisphosphoglycerate mutase (EC 5.4.2.4) from Homo sapiens (see 3 papers)
45% identity, 99% coverage of query (228 bits)
2h4zA / P07738 Human bisphosphoglycerate mutase complexed with 2,3- bisphosphoglycerate (see paper)
45% identity, 99% coverage of query (228 bits)
2f90A Crystal structure of bisphosphoglycerate mutase in complex with 3-phosphoglycerate and alf4-
45% identity, 99% coverage of query (227 bits)
PMGE_MOUSE / P15327 Bisphosphoglycerate mutase; BPGM; 2,3-bisphosphoglycerate mutase, erythrocyte; 2,3-bisphosphoglycerate synthase; BPG-dependent PGAM; EC 5.4.2.4; EC 5.4.2.11 from Mus musculus (Mouse) (see 2 papers)
45% identity, 99% coverage of query (224 bits)
7n3rB The ternary complex of human bisphosphoglycerate mutase with 3- phosphoglycerate and 2-phosphoglycolate
47% identity, 91% coverage of query (221 bits)
Q2YJN6 phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) (EC 5.4.2.11) from Brucella abortus (see paper)
45% identity, 87% coverage of query (170 bits)
GPM2 phosphoglycerate mutase from Candida albicans (see paper)
38% identity, 97% coverage of query (168 bits)
GPMA2_ARATH / F4I8M8 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 2; BPG-dependent PGAM 2; PGAM 2; Phosphoglyceromutase 2; dPGM 2; EC 5.4.2.11 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
39% identity, 85% coverage of query (165 bits)
PMGY_SCHPO / P36623 Phosphoglycerate mutase; PGAM; BPG-dependent PGAM; MPGM; Phosphoglyceromutase; EC 5.4.2.11 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
gpm1 / RF|NP_594889.1 monomeric 2,3-bisphosphoglycerate (BPG)-dependent phosphoglycerate mutase (PGAM), Gpm1; EC 5.4.2.1 from Schizosaccharomyces pombe (see paper)
40% identity, 88% coverage of query (164 bits)
PMG3_YEAST / Q12326 Phosphoglycerate mutase 3; PGAM 3; BPG-dependent PGAM 3; MPGM 3; Phosphoglyceromutase 3; EC 5.4.2.11 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
30% identity, 99% coverage of query (128 bits)
PMG2_YEAST / Q12008 Phosphoglycerate mutase 2; PGAM 2; BPG-dependent PGAM 2; MPGM 2; Phosphoglyceromutase 2; EC 5.4.2.11 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
30% identity, 98% coverage of query (120 bits)
Build an alignment for 208445 and 45 homologs with ≥ 30% identity
Or download the sequences
PHOE_BACSU / O07617 Uncharacterized phosphatase PhoE; EC 3.1.3.- from Bacillus subtilis (strain 168) (see 2 papers)
26% identity, 80% coverage of query (61.2 bits)
PSPB_HYDTT / D3DFP8 Putative phosphoserine phosphatase 2; PSP 2; PSPase 2; Metal-independent phosphoserine phosphatase 2; iPSP2; O-phosphoserine phosphohydrolase 2; EC 3.1.3.3 from Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6) (see paper)
D3DFP8 phosphoserine phosphatase (EC 3.1.3.3) from Hydrogenobacter thermophilus (see paper)
29% identity, 80% coverage of query (58.2 bits)
SUGPH_MYCTU / Q6MWZ7 Acid phosphatase; Broad-specificity phosphatase; Fructose-1,6-bisphosphatase; FBPase; EC 3.1.3.2; EC 3.1.3.11 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
27% identity, 89% coverage of query (54.7 bits)
1h2eA / Q9ALU0 Bacillus stearothermophilus phoe (previously known as yhfr) in complex with phosphate (see paper)
28% identity, 75% coverage of query (52.8 bits)
1h2fA Bacillus stearothermophilus phoe (previously known as yhfr) in complex with trivanadate
28% identity, 75% coverage of query (52.8 bits)
SERCL_ARATH / F4KI56 Metal-independent phosphoserine phosphatase; iPSP; Phosphoglycerate mutase-like protein 3; EC 3.1.3.3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
26% identity, 77% coverage of query (48.9 bits)
1k6mA / P16118 Crystal structure of human liver 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase (see paper)
25% identity, 82% coverage of query (48.5 bits)
1tipA The bisphosphatase domain of the bifunctional rat liver 6- phosphofructo-2-kinase/fructose-2,6-bisphosphatase
26% identity, 83% coverage of query (48.5 bits)
1c81A Michaelis complex of fructose-2,6-bisphosphatase
26% identity, 83% coverage of query (48.5 bits)
1c80A Regulatory complex of fructose-2,6-bisphosphatase
26% identity, 83% coverage of query (48.5 bits)
1c7zA Regulatory complex of fructose-2,6-bisphosphatase
26% identity, 83% coverage of query (48.5 bits)
1fbtA The bisphosphatase domain of the bifunctional rat liver 6- phosphofructo-2-kinase/fructose-2,6-bisphosphatase
26% identity, 82% coverage of query (47.4 bits)
F261_RAT / P07953 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1; 6PF-2-K/Fru-2,6-P2ase 1; PFK/FBPase 1; 6PF-2-K/Fru-2,6-P2ase liver isozyme; EC 2.7.1.105; EC 3.1.3.46 from Rattus norvegicus (Rat) (see 3 papers)
P07953 6-phosphofructo-2-kinase (EC 2.7.1.105); fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Rattus norvegicus (see 4 papers)
26% identity, 82% coverage of query (46.6 bits)
PFKFB1 / P16118 Fructose-2,6-bisphosphatase (EC 3.1.3.46; EC 2.7.1.105) from Homo sapiens (see 7 papers)
F261_HUMAN / P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1; 6PF-2-K/Fru-2,6-P2ase 1; PFK/FBPase 1; 6PF-2-K/Fru-2,6-P2ase liver isozyme; EC 2.7.1.105; EC 3.1.3.46 from Homo sapiens (Human) (see 2 papers)
P16118 6-phosphofructo-2-kinase (EC 2.7.1.105); fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Homo sapiens (see 5 papers)
25% identity, 82% coverage of query (43.9 bits)
Or start over
Lawrence Berkeley National Laboratory