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Searching for up to 100 curated homologs for 208464 MicrobesOnline__882:208464 (520 a.a.)

Found high-coverage hits (≥70%) to 38 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

YdfD/YisV / VIMSS6924547 YdfD/YisV regulator of Metabolite transport (activator/repressor) from Paenibacillus sp. JDR-2
    32% identity, 97% coverage of query (247 bits)

3aovA / O57946 Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with plp
    34% identity, 70% coverage of query (234 bits)

O57946 kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Pyrococcus horikoshii (see paper)
    34% identity, 70% coverage of query (234 bits)

3wx9A Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with pmp, gla, 4ad, 2og, glu and kya
    34% identity, 70% coverage of query (234 bits)

3av7A Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with pmp, kyn as substrates and kya as products
    34% identity, 70% coverage of query (234 bits)

3aowC Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with akg
    34% identity, 70% coverage of query (234 bits)

ARAT1_THELN / H3ZPL1 Aromatic-amino-acid aminotransferase 1; ARAT-I; AROAT; EC 2.6.1.57 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see paper)
    33% identity, 70% coverage of query (222 bits)

A0A060PQX5 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Thermococcus sp. (see paper)
    34% identity, 70% coverage of query (221 bits)

1wstA / Q9V2W5 Crystal structure of multiple substrate aminotransferase (msat) from thermococcus profundus
    33% identity, 70% coverage of query (213 bits)

YdcR / b1439 fused putative DNA-binding transcriptional regulator/putative aminotransferase YdcR from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ydcR / MB|P77730 uncharacterized HTH-type transcriptional regulator ydcR from Escherichia coli K12 (see 3 papers)
    32% identity, 96% coverage of query (210 bits)

YjiR / b4340 fused putative DNA-binding transcriptional regulator/putative aminotransferase YjiR from Escherichia coli K-12 substr. MG1655 (see 5 papers)
yjiR / RF|NP_418760 uncharacterized HTH-type transcriptional regulator yjiR from Escherichia coli K12 (see 2 papers)
    31% identity, 96% coverage of query (209 bits)

Build an alignment

Build an alignment for 208464 and 11 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

YdfD/YisV / VIMSS63013 YdfD/YisV regulator of Metabolite transport (activator/repressor) from Bacillus halodurans C-125
    27% identity, 97% coverage of query (189 bits)

YdfD/YisV / VIMSS822665 YdfD/YisV regulator of Metabolite transport (activator/repressor) from Bacillus clausii KSM-K16
    26% identity, 98% coverage of query (186 bits)

DVU0030 / VIMSS7650531 DVU0030 regulator of Amino acid transport from Desulfovibrio magneticus RS-1
    30% identity, 96% coverage of query (179 bits)

DVU0030 / VIMSS8508254 DVU0030 regulator of Amino acid transport from Desulfovibrio salexigens DSM 2638
    26% identity, 98% coverage of query (170 bits)

DVU0030 / VIMSS8501445 DVU0030 regulator of Amino acid transport from Desulfovibrio vulgaris str. Miyazaki F
    28% identity, 97% coverage of query (168 bits)

TAUR_RHOCB / D5AKX9 HTH-type transcriptional regulator TauR from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) (see paper)
    31% identity, 98% coverage of query (166 bits)

DVU0030 / VIMSS408289 DVU0030 regulator of Amino acid transport from Desulfovibrio vulgaris Hildenborough
    26% identity, 96% coverage of query (162 bits)

DVU0030 / VIMSS7454265 DVU0030 regulator of Amino acid transport from Desulfohalobium retbaense DSM 5692
    26% identity, 96% coverage of query (159 bits)

DVU0030 / VIMSS393253 DVU0030 regulator of Amino acid transport from Desulfovibrio desulfuricans G20
    26% identity, 95% coverage of query (159 bits)

DVU0030 / VIMSS7533539 DVU0030 regulator of Amino acid transport from Desulfomicrobium baculatum DSM 4028
    28% identity, 96% coverage of query (157 bits)

7zlaB / Q5WKW3 Cryo-em structure of holo-pdxr from bacillus clausii bound to its target DNA in the half-closed conformation (see paper)
    27% identity, 91% coverage of query (156 bits)

NORG_STAA8 / Q2G1P1 HTH-type transcriptional regulator NorG from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
    22% identity, 92% coverage of query (155 bits)

GABR_BACSU / P94426 HTH-type transcriptional regulatory protein GabR from Bacillus subtilis (strain 168) (see 2 papers)
    28% identity, 99% coverage of query (155 bits)

1vp4A / Q9X0L5 Crystal structure of a putative aminotransferase (tm1131) from thermotoga maritima msb8 at 1.82 a resolution
    26% identity, 72% coverage of query (152 bits)

tdiD / A7XRY8 L-tryptophan:phenylpyruvate aminotransferase (EC 2.6.1.28) from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (see 3 papers)
TDID_EMENI / A7XRY8 Aminotransferase tdiD; Terrequinone biosynthesis protein D; EC 2.6.1.28 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 5 papers)
A7XRY8 tryptophan-phenylpyruvate transaminase (EC 2.6.1.28) from Aspergillus nidulans (see 2 papers)
    28% identity, 70% coverage of query (146 bits)

3ue8A Kynurenine aminotransferase ii inhibitors
    25% identity, 70% coverage of query (138 bits)

2vgzA Crystal structure of human kynurenine aminotransferase ii
    25% identity, 71% coverage of query (136 bits)

tdiD putative aminotransferase from Emericella nidulans (see paper)
    28% identity, 70% coverage of query (133 bits)

Desal_3745 / VIMSS8508801 Desal_3745 regulator of Metabolite transport from Desulfovibrio salexigens DSM 2638
    27% identity, 96% coverage of query (132 bits)

7zn5B / Q5WKW3 Cryo-em structure of holo-pdxr from bacillus clausii bound to its target DNA in the closed conformation, c2 symmetry. (see paper)
    25% identity, 91% coverage of query (131 bits)

S4UF58 tryptophan transaminase (EC 2.6.1.27) from Malassezia furfur (see paper)
    25% identity, 75% coverage of query (122 bits)

PDXR_CORGL / Q8NS92 HTH-type pyridoxine biosynthesis transcriptional regulator PdxR from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
    26% identity, 95% coverage of query (117 bits)

A0A0D1E3F3 tryptophan transaminase (EC 2.6.1.27) from Ustilago maydis (see paper)
    25% identity, 80% coverage of query (109 bits)

PdxR / VIMSS3789276 PdxR regulator of Pyridoxine biosynthesis, effector Pyridoxal-5-phosphate from Streptococcus gordonii str. Challis substr. CH1
    23% identity, 75% coverage of query (107 bits)

6hnvB Crystal structure of aminotransferase aro9 from c. Albicans with ligands
    26% identity, 70% coverage of query (100 bits)

6hnvA Crystal structure of aminotransferase aro9 from c. Albicans with ligands
    26% identity, 70% coverage of query (100 bits)

6hndB / A0A1D8PMC5 Crystal structure of the aromatic aminotransferase aro9 from c. Albicans (see paper)
    26% identity, 70% coverage of query (97.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory