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Searching for up to 100 curated homologs for 2629601819 IMG__TrieryIMS101_FD:2629601819 (437 a.a.)

Found high-coverage hits (≥70%) to 23 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

THRC_METAC / Q8TQD4 Threonine synthase; TS; EC 4.2.3.1 from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) (see paper)
GB|AAM05023.1 threonine synthase; EC 4.2.3.1 from Methanosarcina acetivorans C2A (see paper)
    39% identity, 92% coverage of query (265 bits)

O66740 threonine synthase (EC 4.2.3.1) from Aquifex aeolicus (see paper)
    37% identity, 79% coverage of query (185 bits)

2zsjA / O66740 Crystal structure of threonine synthase from aquifex aeolicus vf5
    37% identity, 79% coverage of query (185 bits)

P83823 threonine synthase (EC 4.2.3.1) from Thermus thermophilus (see paper)
Q5SL02 threonine synthase (EC 4.2.3.1) from Thermus thermophilus (see 2 papers)
3aexA / Q5SL02 Catalytic intermediate analogue of threonine synthase from thermus thermophilus hb8 (see paper)
    37% identity, 80% coverage of query (177 bits)

1uimA Crystal structure of threonine synthase from thermus thermophilus hb8, orthorhombic crystal form
    37% identity, 80% coverage of query (177 bits)

1v7cA Crystal structure of threonine synthase from thermus thermophilus hb8 in complex with a substrate analogue
    37% identity, 80% coverage of query (177 bits)

3aeyA Apo form of threonine synthase from thermus thermophilus hb8
    37% identity, 80% coverage of query (177 bits)

thrC / CAA82669.1 threonine synthase from Bacillus sp. (see paper)
    37% identity, 74% coverage of query (176 bits)

6nmxA / A8HUA2 Threonine synthase from bacillus subtilis atcc 6633 with plp and appa (see paper)
    35% identity, 79% coverage of query (176 bits)

6cgqB Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala
    36% identity, 79% coverage of query (176 bits)

6cgqA Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala
    35% identity, 79% coverage of query (173 bits)

A0R220 Threonine synthase; TS; EC 4.2.3.1 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
    36% identity, 75% coverage of query (165 bits)

THRC_MYCTU / P9WG59 Threonine synthase; TS; EC 4.2.3.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P9WG59 threonine synthase (EC 4.2.3.1) from Mycobacterium tuberculosis (see 2 papers)
    35% identity, 76% coverage of query (162 bits)

2d1fA / P9WG59 Structure of mycobacterium tuberculosis threonine synthase (see paper)
    35% identity, 75% coverage of query (160 bits)

THRC2_ARATH / Q9SSP5 Threonine synthase 2, chloroplastic; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    31% identity, 76% coverage of query (129 bits)

Build an alignment

Build an alignment for 2629601819 and 15 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

THRC1_ARATH / Q9S7B5 Threonine synthase 1, chloroplastic; Protein METHIONINE OVER-ACCUMULATOR 2; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    29% identity, 82% coverage of query (127 bits)

2c2bA Crystallographic structure of arabidopsis thaliana threonine synthase complexed with pyridoxal phosphate and s-adenosylmethionine
    29% identity, 82% coverage of query (127 bits)

2c2gA / Q9S7B5 Crystal structure of threonine synthase from arabidopsis thaliana in complex with its cofactor pyridoxal phosphate (see paper)
    28% identity, 82% coverage of query (117 bits)

DvMF_1945 threonine synthase (EC 4.2.3.1) from Desulfovibrio vulgaris Miyazaki F
    26% identity, 85% coverage of query (87.8 bits)

MA_3297 / Q8TKU7 cysteate synthase monomer (EC 2.5.1.76) from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) (see paper)
CYAS_METAC / Q8TKU7 Cysteate synthase; CS; Cya synthase; EC 2.5.1.76 from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) (see paper)
Q8TKU7 cysteate synthase (EC 2.5.1.76) from Methanosarcina acetivorans (see paper)
    26% identity, 86% coverage of query (80.5 bits)

TSAL_GEOSL / Q74FW6 L-threonine ammonia-lyase; L-serine ammonia-lyase; Threonine/serine ammonia-lyase; EC 4.3.1.19; EC 4.3.1.17 from Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) (see paper)
Q74FW6 threonine ammonia-lyase (EC 4.3.1.19) from Geobacter sulfurreducens (see paper)
    26% identity, 76% coverage of query (52.8 bits)

SDSL_MOUSE / Q8R238 Serine dehydratase-like; L-serine deaminase; L-serine dehydratase/L-threonine deaminase; L-threonine dehydratase; TDH; SDH; EC 4.3.1.17; EC 4.3.1.19 from Mus musculus (Mouse) (see paper)
    25% identity, 70% coverage of query (48.1 bits)

TRP5 likely tryptophan synthetase alpha chain from Candida albicans (see paper)
    25% identity, 70% coverage of query (46.2 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory