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Searching for up to 100 curated homologs for 349724 FitnessBrowser__Btheta:349724 (448 a.a.)

Found high-coverage hits (≥70%) to 24 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 2.A.1.4.6 / Q9Z7N9 Glucose-6-P:Pi antiporter, Hpt (may also transport other organophosphates including C3 organophosphates) from Chlamydia pneumoniae (Chlamydophila pneumoniae) (see 3 papers)
    34% identity, 82% coverage of query (217 bits)

UhpC / b3667 inner membrane protein sensing glucose-6-phosphate from Escherichia coli K-12 substr. MG1655 (see 4 papers)
UHPC_ECOLI / P09836 Membrane sensor protein UhpC from Escherichia coli (strain K12) (see 5 papers)
TC 2.A.1.4.4 / P09836 Hexose-P:Pi antiporter regulatory protein; senses external glucose-6-P and transports it with high affinity and low efficiency from Escherichia coli (see 7 papers)
uhpC regulatory protein UhpC from Escherichia coli K12 (see 7 papers)
uhpC / ECOCYC|GLU-UHPC membrane protein regulates uhpT expression from Escherichia coli K12 (see 2 papers)
    31% identity, 88% coverage of query (207 bits)

Build an alignment

Build an alignment for 349724 and 2 homologs with ≥ 30% identity

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Change minimum %identity:

Additional hits (identity < 30%)

Q9HTV5 ABC-type glycerol 3-phosphate transporter (EC 7.6.2.10) from Pseudomonas aeruginosa (see paper)
    28% identity, 86% coverage of query (176 bits)

GlpT / b2240 sn-glycerol 3-phosphate:phosphate antiporter from Escherichia coli K-12 substr. MG1655 (see 24 papers)
glpT / P08194 sn-glycerol 3-phosphate:phosphate antiporter from Escherichia coli (strain K12) (see 48 papers)
TC 2.A.1.4.3 / P08194 Glycerol-P:Pi antiporter (may function by a 'rocker switch' mechanism; Law et al., 2007). The 3-d structure is known (3.3Å resolution) (Huang et al., 2003; Lemieux et al., 2005; Lemieux, 2007) from Escherichia coli (see 7 papers)
    28% identity, 85% coverage of query (175 bits)

A0A0H3JLD7 ABC-type glycerol 3-phosphate transporter (EC 7.6.2.10) from Staphylococcus aureus (see paper)
    31% identity, 90% coverage of query (174 bits)

TC 2.A.1.4.11 / Q9ZE92 Glycerol-3-phosphate:inorganic phosphate antiporter, GlpT from Rickettsia prowazekii (strain Madrid E)
    32% identity, 83% coverage of query (162 bits)

TC 2.A.1.4.2 / P12681 P-glycerate:Pi antiporter, Pgt from Salmonella typhimurium (see 2 papers)
    29% identity, 87% coverage of query (154 bits)

TC 2.A.1.4.10 / O69759 2-phosphonoacetate/2-phosponopropionate uptake porter of 428 aas, PhnB from Pseudomonas fluorescens
    28% identity, 83% coverage of query (130 bits)

G6PT1_HUMAN / O43826 Glucose-6-phosphate exchanger SLC37A4; Glucose-5-phosphate transporter; Glucose-6-phosphate translocase; Solute carrier family 37 member 4; Transformation-related gene 19 protein; TRG-19 from Homo sapiens (Human) (see 24 papers)
TC 2.A.1.4.5 / O43826 Microsomal (ER/Golgi) glucose-6-P:Pi antiporter (glycogen storage disease (GSD1b and 1c); Gierke''s disease protein) (SLC37A2 in mice, associated with white adipose tissue obesity and expressed at high levels in macrophage) (4 isoforms present in humans (Chen et al., 2008)) from Homo sapiens (Human) (see 23 papers)
SLC37A4 / RF|NP_001458.1 glucose-6-phosphate translocase from Homo sapiens
    25% identity, 79% coverage of query (120 bits)

UhpT / b3666 hexose-6-phosphate:phosphate antiporter from Escherichia coli K-12 substr. MG1655 (see 12 papers)
uhpT / P0AGC0 hexose-6-phosphate:phosphate antiporter from Escherichia coli (strain K12) (see 14 papers)
UHPT_ECOLI / P0AGC0 Hexose-6-phosphate:phosphate antiporter from Escherichia coli (strain K12) (see 11 papers)
    28% identity, 83% coverage of query (117 bits)

Q9SA71 ABC-type glycerol 3-phosphate transporter (EC 7.6.2.10) from Arabidopsis thaliana (see paper)
    24% identity, 88% coverage of query (89.4 bits)

LgoT / b4356 galactonate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 2 papers)
lgoT / P39398 galactonate:H+ symporter from Escherichia coli (strain K12) (see 2 papers)
LGOT_ECOLI / P39398 Probable L-galactonate transporter; Galactonate:H(+) symporter from Escherichia coli (strain K12) (see 2 papers)
yjjL / RF|NP_418776 inner membrane transport protein yjjL from Escherichia coli K12 (see 2 papers)
    24% identity, 89% coverage of query (83.2 bits)

TC 2.A.1.53.6 / I7I0I1 MFS uptake permease specific for pyrimidines, PhtC of 422 aas and 12 TMSs from Legionella pneumophila subsp. pneumophila
    24% identity, 92% coverage of query (80.5 bits)

GudP / b2789 galactarate/D-glucarate transporter GudP from Escherichia coli K-12 substr. MG1655 (see 5 papers)
gudP / Q46916 galactarate/D-glucarate transporter GudP from Escherichia coli (strain K12) (see 5 papers)
GUDP_ECOLI / Q46916 Probable galactarate/D-glucarate transporter GudP from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.1.14.40 / C4ZZU4 Glucarate transporter, GudP.  Encoded in an operon with GudD, a glucarate dehydratase from Escherichia coli (strain K12 / MC4100 / BW2952)
    25% identity, 81% coverage of query (79.0 bits)

TC 2.A.1.15.4 / P94131 cis,cis-muconate porter, MucK from Acinetobacter calcoaceticus (see 2 papers)
mucK / AAC27117.1 cis,cis-muconate transport protein MucK from Acinetobacter baylyi (see paper)
    25% identity, 79% coverage of query (76.3 bits)

PS417_04205 D-galacturonate transporter (MFS superfamily) from Pseudomonas simiae WCS417
    23% identity, 81% coverage of query (67.0 bits)

HSERO_RS23010 D-galacturonate transporter ExuT from Herbaspirillum seropedicae SmR1
    21% identity, 80% coverage of query (62.0 bits)

TC 2.A.1.14.14 / Q8FDB7 Probable D-galactarate (glucarate?):H+ symporter, GarP or YhaU from Escherichia coli O6 (see paper)
    23% identity, 80% coverage of query (62.0 bits)

GarP / b3127 galactarate/D-glucarate transporter GarP from Escherichia coli K-12 substr. MG1655 (see 6 papers)
garP / P0AA80 galactarate/D-glucarate transporter GarP from Escherichia coli (strain K12) (see 5 papers)
GARP_ECOLI / P0AA80 Probable galactarate/D-glucarate transporter GarP from Escherichia coli (strain K12) (see 2 papers)
    23% identity, 80% coverage of query (62.0 bits)

GUDP_BACSU / P42237 Probable galactarate/D-glucarate transporter GudP from Bacillus subtilis (strain 168) (see paper)
TC 2.A.1.14.1 / P42237 Glucarate porter from Bacillus subtilis (see 3 papers)
    24% identity, 75% coverage of query (60.1 bits)

S17A9_MOUSE / Q8VCL5 Voltage-gated purine nucleotide uniporter SLC17A9; Solute carrier family 17 member 9; Vesicular nucleotide transporter; VNUT from Mus musculus (Mouse) (see 5 papers)
    23% identity, 81% coverage of query (58.5 bits)

TC 2.A.1.53.1 / Q5ZY33 The threonine uptake permease, PhtA (Sauer et al., 2005) (required for maximal growth in macrophages and Acanthamoeba castellanii) (see paper)
    22% identity, 82% coverage of query (54.7 bits)

TC 2.A.1.53.7 / I7HKH2 MFS uptake permease, probably specific for pyrimidines, PhtD of 427 aas and 12 TMSs from Legionella pneumophila subsp. pneumophila
    24% identity, 80% coverage of query (48.1 bits)

ANTR6_ARATH / Q3E9A0 Probable anion transporter 6, chloroplastic; Phosphate transporter PHT4;5 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    19% identity, 76% coverage of query (47.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory