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Searching for up to 100 curated homologs for 349858 BT0330 ketoisovalerate oxidoreductase subunit vorA (NCBI ptt file) (235 a.a.)

Found high-coverage hits (≥70%) to 30 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

VORA_METTM / P80907 Ketoisovalerate oxidoreductase subunit VorA; VOR; 2-oxoisovalerate oxidoreductase alpha chain; 2-oxoisovalerate-ferredoxin oxidoreductase subunit alpha; EC 1.-.-.- from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see paper)
    48% identity, 98% coverage of query (245 bits)

korB / Q6LXN3 2-oxoglutarate ferredoxin oxidoreductase β subunit (EC 1.2.7.3) from Methanococcus maripaludis (strain S2 / LL) (see 2 papers)
    34% identity, 85% coverage of query (115 bits)

korB / O53181 2-oxoglutarate:ferredoxin oxidoreductase β subunit (EC 1.2.7.3) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
KORB_MYCTU / O53181 2-oxoglutarate oxidoreductase subunit KorB; Alpha-ketoglutarate oxidoreductase subunit beta; KG oxidoreductase subunit beta; KGO subunit beta; KOR subunit beta; EC 1.2.7.3 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    33% identity, 86% coverage of query (108 bits)

KORB_METTM / P80905 2-oxoglutarate synthase subunit KorB; 2-ketoglutarate oxidoreductase beta chain; KOR; 2-oxoglutarate-ferredoxin oxidoreductase subunit beta; EC 1.2.7.3 from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see paper)
    32% identity, 91% coverage of query (106 bits)

oorB / O25312 2-oxoglutarate-acceptor oxidoreductase subunit OorB (EC 1.2.7.3) from Helicobacter pylori (strain ATCC 700392 / 26695) (see 2 papers)
    32% identity, 91% coverage of query (100 bits)

korB / Q9AJL9 2-oxoglutarate ferredoxin oxidoreductase β subunit (EC 1.2.7.3) from Hydrogenobacter thermophilus (see paper)
Q9AJL9 2-oxoglutarate synthase (subunit 1/2) (EC 1.2.7.3) from Hydrogenobacter thermophilus (see 3 papers)
    31% identity, 86% coverage of query (89.4 bits)

Build an alignment

Build an alignment for 349858 and 6 homologs with ≥ 30% identity

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Change minimum %identity:

Additional hits (identity < 30%)

OFOB2_AERPE / Q9YBX8 2-oxoacid:ferredoxin oxidoreductase 2, subunit beta; OFOR2; EC 1.2.7.11 from Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) (see paper)
    29% identity, 93% coverage of query (84.7 bits)

Q4J6I8 2-oxoacid oxidoreductase (ferredoxin) (subunit 1/2) (EC 1.2.7.11) from Sulfolobus acidocaldarius (see paper)
    30% identity, 84% coverage of query (81.3 bits)

OFOB_SACSO / A0A0E3KBH3 2-oxoacid:ferredoxin oxidoreductase subunit beta; OFOR; EC 1.2.7.11 from Saccharolobus solfataricus (Sulfolobus solfataricus) (see paper)
    29% identity, 84% coverage of query (80.5 bits)

5b46B / Q96XT4 2-oxoacid:ferredoxin oxidoreductase 2 from sulfolobus tokodai - ligand free form (see paper)
    32% identity, 84% coverage of query (79.3 bits)

OFOB2_SULTO / Q96XT4 2-oxoacid:ferredoxin oxidoreductase 2, subunit beta; OFOR2; EC 1.2.7.11 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
Q96XT4 2-oxoacid oxidoreductase (ferredoxin) (subunit 1/2) (EC 1.2.7.11) from Sulfurisphaera tokodaii (see paper)
    32% identity, 84% coverage of query (79.0 bits)

Q8RJQ9 2-oxoglutarate synthase (subunit 1/2) (EC 1.2.7.3) from Thauera aromatica (see paper)
    31% identity, 83% coverage of query (76.6 bits)

porB / O27771 pyruvate synthase subunit β (EC 1.2.7.1) from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (see 7 papers)
    30% identity, 88% coverage of query (68.9 bits)

PORB_METTM / P80901 Pyruvate synthase subunit PorB; Pyruvate oxidoreductase beta chain; POR; Pyruvic-ferredoxin oxidoreductase subunit beta; EC 1.2.7.1 from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see paper)
    29% identity, 88% coverage of query (68.2 bits)

Q93RA2 2-oxoglutarate synthase (subunit 1/2) (EC 1.2.7.3) from Hydrogenobacter thermophilus (see paper)
D3DIA2 2-oxoglutarate synthase (subunit 4/5) (EC 1.2.7.3) from Hydrogenobacter thermophilus (see 2 papers)
    25% identity, 93% coverage of query (66.6 bits)

Q51805 pyruvate synthase (subunit 3/4) (EC 1.2.7.1) from Pyrococcus furiosus (see 2 papers)
    28% identity, 87% coverage of query (65.5 bits)

OFOB1_AERPE / Q9YA11 2-oxoacid:ferredoxin oxidoreductase 1, subunit beta; OFOR1; EC 1.2.7.11 from Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) (see paper)
    28% identity, 83% coverage of query (65.1 bits)

5b47B / Q96XT4 2-oxoacid:ferredoxin oxidoreductase 2 from sulfolobus tokodai - pyruvate complex (see paper)
    29% identity, 84% coverage of query (63.9 bits)

OFOB1_SULTO / Q96Y68 2-oxoacid:ferredoxin oxidoreductase 1, subunit beta; OFOR1; EC 1.2.7.11 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see 2 papers)
Q96Y68 2-oxoacid oxidoreductase (ferredoxin) (subunit 1/2) (EC 1.2.7.11) from Sulfurisphaera tokodaii (see paper)
    27% identity, 95% coverage of query (63.5 bits)

porB / Q9LBF8 pyruvate:ferredoxin oxidoreductase β subunit (EC 1.2.7.1) from Hydrogenobacter thermophilus (see 2 papers)
porB / BAA95606.1 pyruvate:ferredoxin oxidoreductase beta subunit from Hydrogenobacter thermophilus (see paper)
    29% identity, 76% coverage of query (63.5 bits)

P72579 2-oxoacid:ferredoxin oxidoreductase β subunit (EC 1.2.7.11; EC 1.2.7.1; EC 1.2.7.3; EC 1.2.7.7) from Sulfolobus sp. (see 2 papers)
OFOB_SULSP / P72579 2-oxoacid:ferredoxin oxidoreductase subunit beta; OFOR; EC 1.2.7.11 from Sulfolobus sp. (see 3 papers)
P72579 2-oxoacid oxidoreductase (ferredoxin) (subunit 1/2) (EC 1.2.7.11) from Sulfolobus sp. (see 2 papers)
    27% identity, 95% coverage of query (63.2 bits)

5b48B / Q96Y68 2-oxoacid:ferredoxin oxidoreductase 1 from sulfolobus tokodai (see paper)
    28% identity, 84% coverage of query (60.5 bits)

W8CQB2 pyruvate synthase (subunit 3/4) (EC 1.2.7.1); pyruvate decarboxylase (subunit 3/4) (EC 4.1.1.1) from Thermococcus guaymasensis (see paper)
    28% identity, 87% coverage of query (58.5 bits)

Q5JIJ6 pyruvate synthase (subunit 1/3) (EC 1.2.7.1) from Thermococcus kodakarensis (see paper)
    28% identity, 87% coverage of query (57.4 bits)

P80522 pyruvate synthase (subunit 3/4) (EC 1.2.7.1) from Methanosarcina barkeri (see paper)
    26% identity, 94% coverage of query (55.5 bits)

Q9P9E4 pyruvate synthase (subunit 4/5) (EC 1.2.7.1) from Methanococcus maripaludis (see paper)
    25% identity, 88% coverage of query (51.2 bits)

porB / Q56317 pyruvate:ferredoxin oxidoreductase β subunit (EC 1.2.7.1) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 7 papers)
Q56317 pyruvate synthase (subunit 3/4) (EC 1.2.7.1) from Thermotoga maritima (see 2 papers)
    24% identity, 93% coverage of query (50.1 bits)

OORB_MOOTA / Q2RI42 Oxalate oxidoreductase subunit beta; OOR subunit beta; EC 1.2.7.10 from Moorella thermoacetica (strain ATCC 39073 / JCM 9320) (see paper)
Q2RI42 oxalate oxidoreductase (subunit 2/3) (EC 1.2.7.10) from Moorella thermoacetica (see paper)
5exeC / Q2RI42 Crystal structure of oxalate oxidoreductase from moorella thermoacetica bound with carboxy-tpp adduct (see paper)
    23% identity, 88% coverage of query (48.1 bits)

5exdF Crystal structure of oxalate oxidoreductase from moorella thermoacetica bound with carboxy-di-oxido-methyl-tpp (coom-tpp) intermediate
    23% identity, 88% coverage of query (48.1 bits)

5c4iC Structure of an oxalate oxidoreductase
    23% identity, 88% coverage of query (48.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory