Sites on a Tree

 

Searching for up to 100 curated homologs for 349859 FitnessBrowser__Btheta:349859 (295 a.a.)

Found high-coverage hits (≥70%) to 23 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

VORB_METTM / P80908 Ketoisovalerate oxidoreductase subunit VorB; VOR; 2-oxoisovalerate ferredoxin reductase subunit beta; 2-oxoisovalerate oxidoreductase beta chain; EC 1.2.7.7 from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see paper)
    51% identity, 99% coverage of query (274 bits)

KORA_METTM / P80904 2-oxoglutarate synthase subunit KorA; 2-ketoglutarate oxidoreductase alpha chain; KOR; 2-oxoglutarate-ferredoxin oxidoreductase subunit alpha; EC 1.2.7.3 from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see paper)
    33% identity, 98% coverage of query (157 bits)

korA / Q6M1B3 2-oxoglutarate ferredoxin oxidoreductase α subunit (EC 1.2.7.3) from Methanococcus maripaludis (strain S2 / LL) (see 2 papers)
    34% identity, 96% coverage of query (144 bits)

oorA / O25311 2-oxoglutarate-acceptor oxidoreductase subunit OorA (EC 1.2.7.3) from Helicobacter pylori (strain ATCC 700392 / 26695) (see paper)
    32% identity, 98% coverage of query (129 bits)

Build an alignment

Build an alignment for 349859 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

A0L8G4 2-oxoglutarate synthase (subunit 2/2) (EC 1.2.7.3) from Magnetococcus marinus (see paper)
    29% identity, 99% coverage of query (106 bits)

6n2nA / A0L8G4 Crystal structure of 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus (see paper)
    29% identity, 99% coverage of query (106 bits)

6n2oC 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus with 2-oxoglutarate, coenzyme a and succinyl-coa bound
    29% identity, 99% coverage of query (106 bits)

6n2oA 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus with 2-oxoglutarate, coenzyme a and succinyl-coa bound
    29% identity, 99% coverage of query (106 bits)

korA / Q9AJM0 2-oxoglutarate:ferredoxin oxidoreductase α subunit (EC 1.2.7.3) from Hydrogenobacter thermophilus (see paper)
Q9AJM0 2-oxoglutarate synthase (subunit 2/2) (EC 1.2.7.3) from Hydrogenobacter thermophilus (see 3 papers)
    28% identity, 88% coverage of query (95.9 bits)

korA / O53182 2-oxoglutarate:ferredoxin oxidoreductase α/γ subunit (EC 1.2.7.3) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
KORA_MYCTU / O53182 2-oxoglutarate oxidoreductase subunit KorA; Alpha-ketoglutarate oxidoreductase subunit alpha/gamma; KG oxidoreductase subunit alpha/gamma; KGO subunit alpha/gamma; KOR subunit alpha/gamma; EC 1.2.7.3 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    28% identity, 93% coverage of query (77.0 bits)

O87870 2-oxoglutarate synthase (subunit 2/2) (EC 1.2.7.3) from Thauera aromatica (see paper)
    25% identity, 98% coverage of query (72.0 bits)

OFOA2_AERPE / Q9YBX7 2-oxoacid:ferredoxin oxidoreductase 2, subunit alpha; OFOR2; EC 1.2.7.11 from Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) (see paper)
    26% identity, 81% coverage of query (71.2 bits)

OFOA_SACSO / A0A0E3JT70 2-oxoacid:ferredoxin oxidoreductase subunit alpha; OFOR; EC 1.2.7.11 from Saccharolobus solfataricus (Sulfolobus solfataricus) (see paper)
    26% identity, 95% coverage of query (65.9 bits)

OFOA1_AERPE / Q9YA13 2-oxoacid:ferredoxin oxidoreductase 1, subunit alpha; OFOR1; EC 1.2.7.11 from Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) (see paper)
    23% identity, 80% coverage of query (63.5 bits)

PORA_METTM / P80900 Pyruvate synthase subunit PorA; Pyruvate oxidoreductase alpha chain; POR; Pyruvic-ferredoxin oxidoreductase subunit alpha; EC 1.2.7.1 from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see paper)
    25% identity, 94% coverage of query (60.8 bits)

Q5JIJ7 pyruvate synthase (subunit 2/3) (EC 1.2.7.1) from Thermococcus kodakarensis (see paper)
    24% identity, 88% coverage of query (58.2 bits)

Q9P9E5 pyruvate synthase (subunit 5/5) (EC 1.2.7.1) from Methanococcus maripaludis (see paper)
    24% identity, 93% coverage of query (57.4 bits)

porA / B0R4X6 pyruvate—ferredoxin oxidoreductaseα subunit (EC 1.2.7.1) from Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) (see 10 papers)
    23% identity, 96% coverage of query (57.4 bits)

padG / Q8L3B1 phenylglyoxylate dehydrogenase (acylating) subunit PadG (EC 1.2.1.58) from Aromatoleum evansii (see 2 papers)
PADG_AROEV / Q8L3B1 NADH-dependent phenylglyoxylate dehydrogenase subunit alpha; Phenylglyoxylate:NAD oxidoreductase; Phenylglyoxylate:acceptor oxidoreductase; EC 1.2.1.58 from Aromatoleum evansii (Azoarcus evansii) (see paper)
    25% identity, 85% coverage of query (57.4 bits)

Q93RA3 2-oxoglutarate synthase (subunit 2/2) (EC 1.2.7.3) from Hydrogenobacter thermophilus (see paper)
D3DIA1 2-oxoglutarate synthase (subunit 5/5) (EC 1.2.7.3) from Hydrogenobacter thermophilus (see 2 papers)
    25% identity, 96% coverage of query (53.1 bits)

W8CQR1 pyruvate synthase (subunit 4/4) (EC 1.2.7.1); pyruvate decarboxylase (subunit 4/4) (EC 4.1.1.1) from Thermococcus guaymasensis (see paper)
    24% identity, 88% coverage of query (51.2 bits)

Q51804 pyruvate synthase (subunit 4/4) (EC 1.2.7.1) from Pyrococcus furiosus (see 2 papers)
    23% identity, 81% coverage of query (47.4 bits)

porA / O05651 pyruvate:ferredoxin oxidoreductase α subunit (EC 1.2.7.1) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 7 papers)
O05651 pyruvate synthase (subunit 4/4) (EC 1.2.7.1) from Thermotoga maritima (see 2 papers)
    25% identity, 79% coverage of query (46.6 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory