Sites on a Tree

 

Searching for up to 100 curated homologs for 349867 FitnessBrowser__Btheta:349867 (748 a.a.)

Found high-coverage hits (≥70%) to 74 curated proteins.

Removed hits that are identical to the query, leaving 73

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

No hits had 30% identity

Change minimum %identity:

Additional hits (identity < 30%)

BAB88401.1 isomaltosyltransferase (CtsW) (EC 2.4.1.-) (see protein)
    29% identity, 75% coverage of query (248 bits)

5hxmA / Q8Y4J2 Cycloalternan-forming enzyme from listeria monocytogenes in complex with panose (see paper)
    27% identity, 72% coverage of query (239 bits)

4kwuA 1.9 angstrom resolution crystal structure of uncharacterized protein lmo2446 from listeria monocytogenes egd-e in complex with alpha-d- glucose, beta-d-glucose, magnesium and calcium
    27% identity, 72% coverage of query (239 bits)

BAC54957.1 3-α-isomaltosyltransferase (CtsY;IMT) (EC 2.4.1.-) (see protein)
    28% identity, 72% coverage of query (220 bits)

BAQ19546.1 α-glucosidase (AG31A;BspAG31A) (EC 3.2.1.20) (see protein)
    27% identity, 81% coverage of query (219 bits)

A0A169PW02 alpha-D-xyloside xylohydrolase (EC 3.2.1.177) from uncultured microorganism (see paper)
    30% identity, 73% coverage of query (216 bits)

5zn7A Crystal structure of gh31 alpha-xylosidase from a soil metagenome complexed with xylose
    30% identity, 73% coverage of query (216 bits)

ctsY / Q8RQV0 isomaltosyltransferase (EC 2.4.1.387) from Sporosarcina globispora (see 3 papers)
BAB88403.1 3-α-isomaltosyltransferase (CtsY) (EC 2.4.1.-) (see protein)
    27% identity, 72% coverage of query (214 bits)

BAD34979.1 3-α-isomaltosyltransferase (CtsY;IMT) (EC 2.4.1.-) (see protein)
    27% identity, 72% coverage of query (209 bits)

AGLU_SACS9 / D0KQM8 Alpha-glucosidase; Maltase; EC 3.2.1.20 from Saccharolobus solfataricus (strain 98/2) (Sulfolobus solfataricus) (see paper)
D0KQM8 alpha-glucosidase (EC 3.2.1.20) from Saccharolobus solfataricus (see paper)
    26% identity, 71% coverage of query (196 bits)

P0CD66 alpha-glucosidase (EC 3.2.1.20) from Saccharolobus solfataricus (see 3 papers)
AAC38215.1 α-glucosidase with α-mannosidase activity (MalA;SsMalA;Sso1_0793) (EC 3.2.1.20|3.2.1.24) (see protein)
AAK43151.1 α-glucosidase (MalA;SSO3051) (EC 3.2.1.20) (see protein)
    26% identity, 71% coverage of query (196 bits)

Q745T6 alpha-glucosidase (EC 3.2.1.20) from Thermus thermophilus HB27 (see paper)
    29% identity, 72% coverage of query (187 bits)

Q9HLD0 alpha-glucosidase (EC 3.2.1.20) from Thermoplasma acidophilum (see paper)
CAC11443.1 α-glucosidase (AglA;Ta0298) (EC 3.2.1.20) (see protein)
    26% identity, 70% coverage of query (181 bits)

7p4dAAA Oligosaccharide 4-alpha-D-glucosyltransferase
    24% identity, 74% coverage of query (177 bits)

7p4cAAA Oligosaccharide 4-alpha-D-glucosyltransferase
    24% identity, 74% coverage of query (177 bits)

5npeA Crystal structure of cjagd31b (alpha-transglucosylase from glycoside hydrolase family 31) in complex with beta cyclophellitol aziridine probe ky358
    24% identity, 74% coverage of query (177 bits)

5npbA Crystal structure of cjagd31b (alpha-transglucosylase from glycoside hydrolase family 31) in complex with alpha cyclophellitol cyclosulfate probe me647
    24% identity, 74% coverage of query (177 bits)

4b9zA Crystal structure of agd31b, alpha-transglucosylase, complexed with acarbose
    24% identity, 74% coverage of query (177 bits)

4b9yA Crystal structure of apo agd31b, alpha-transglucosylase in glycoside hydrolase family 31
    24% identity, 74% coverage of query (177 bits)

OL4AG_CELJU / B3PEE6 Oligosaccharide 4-alpha-D-glucosyltransferase; Alpha-glucosidase 31B; CJAgd31B; EC 2.4.1.161 from Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa) (see paper)
ACE84782.1 oligosaccharide α-1,4-transglucosylase 31B (CjAgd31B;CJA_3248) (Agd31B) (EC 2.4.1.161) (see protein)
    24% identity, 72% coverage of query (176 bits)

5npdA Crystal structure of d412n nucleophile mutant cjagd31b (alpha- transglucosylase from glycoside hydrolase family 31) in complex with alpha cyclophellitol aziridine probe cf021
    24% identity, 74% coverage of query (176 bits)

5npcA Crystal structure of d412n nucleophile mutant cjagd31b (alpha- transglucosylase from glycoside hydrolase family 31) in complex with unreacted alpha cyclophellitol cyclosulfate probe me647
    24% identity, 74% coverage of query (176 bits)

5i24A Crystal structure of agd31b, alpha-transglucosylase in glycoside hydrolase family 31, in complex with cyclophellitol aziridine probe cf021
    24% identity, 72% coverage of query (176 bits)

5i23A Crystal structure of agd31b, alpha-transglucosylase in glycoside hydrolase family 31, in complex with cyclophellitol aziridine probe cf022
    24% identity, 72% coverage of query (176 bits)

4ba0A / B3PEE6 Crystal structure of agd31b, alpha-transglucosylase, complexed with 5f-alpha-glcf (see paper)
    24% identity, 72% coverage of query (175 bits)

5f7sA Cycloalternan-degrading enzyme from trueperella pyogenes
    25% identity, 70% coverage of query (173 bits)

5i0fB Cycloalternan-degrading enzyme from trueperella pyogenes in complex with covalent intermediate
    25% identity, 71% coverage of query (173 bits)

4xppA Crystal structure of pedobacter saltans gh31 alpha-galactosidase complexed with d-galactose
    26% identity, 71% coverage of query (173 bits)

5i0gB Cycloalternan-degrading enzyme from trueperella pyogenes in complex with cycloalternan (see paper)
    25% identity, 71% coverage of query (172 bits)

4xpqA / A0A0F7R6D6 Crystal structure of pedobacter saltans gh31 alpha-galactosidase complexed with l-fucose (see paper)
    26% identity, 71% coverage of query (171 bits)

4xpsA Crystal structure of the mutant d365a of pedobacter saltans gh31 alpha-galactosidase complexed with p-nitrophenyl-alpha- galactopyranoside
    26% identity, 71% coverage of query (170 bits)

F9VPH0 alpha-glucosidase (EC 3.2.1.20) from Sulfurisphaera tokodaii (see paper)
BAB67639.1 α-glucosidase (ST2525) (EC 3.2.1.20) (see protein)
    25% identity, 73% coverage of query (169 bits)

BAR72452.1 α-galactosidase (PsGal31A) (Gal31A) (EC 3.2.1.22) (see protein)
    25% identity, 71% coverage of query (164 bits)

AAO78405.1 α-glucosidase (BT3299;BT_3299) (EC 3.2.1.20) (see protein)
    26% identity, 72% coverage of query (158 bits)

GANC_HUMAN / Q8TET4 Neutral alpha-glucosidase C; EC 3.2.1.20 from Homo sapiens (Human) (see paper)
    25% identity, 72% coverage of query (157 bits)

G0SG42 mannosyl-oligosaccharide alpha-1,3-glucosidase (subunit 2/2) (EC 3.2.1.207) from Chaetomium thermophilum (see 2 papers)
    25% identity, 92% coverage of query (154 bits)

P70699 Lysosomal alpha-glucosidase; Acid maltase; EC 3.2.1.20 from Mus musculus (Mouse)
    24% identity, 73% coverage of query (153 bits)

AAH10210.1 α-glucosidase (GAA) (lysosomal) (EC 3.2.1.20) (see protein)
    24% identity, 73% coverage of query (152 bits)

7p32AAA Lysosomal alpha-glucosidase
    24% identity, 73% coverage of query (149 bits)

7p2zAaA Lysosomal alpha-glucosidase
    24% identity, 73% coverage of query (149 bits)

5nn4A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with n-acetyl-cysteine
    24% identity, 73% coverage of query (149 bits)

5nn6A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with n-hydroxyethyl-1-deoxynojirimycin
    24% identity, 73% coverage of query (149 bits)

B5THE3 sucrose alpha-glucosidase (EC 3.2.1.48) from Mus musculus (see paper)
    25% identity, 73% coverage of query (148 bits)

8cb6A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in covalent complex with tamra tagged 1,6-epi-cylcophellitol aziridine activity based probe
    24% identity, 73% coverage of query (148 bits)

8cb1A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with n-pnt-dnm 15
    24% identity, 73% coverage of query (148 bits)

5nn5A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with 1-deoxynojirimycin
    24% identity, 73% coverage of query (148 bits)

5nn8A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with acarbose
    24% identity, 73% coverage of query (148 bits)

5kzwA / P10253 Crystal structure of human gaa
    24% identity, 73% coverage of query (147 bits)

LYAG_BOVIN / Q9MYM4 Lysosomal alpha-glucosidase; Acid maltase; EC 3.2.1.20 from Bos taurus (Bovine) (see paper)
AAF81637.1 acidic α-glucosidase (EC 3.2.1.20) (see protein)
    23% identity, 73% coverage of query (145 bits)

BAA25890.2 acid α-glucosidase (Gaa2;GAAII) (EC 3.2.1.20) (see protein)
    23% identity, 73% coverage of query (145 bits)

LYAG_HUMAN / P10253 Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; EC 3.2.1.20 from Homo sapiens (Human) (see 46 papers)
P10253 alpha-glucosidase (EC 3.2.1.20) from Homo sapiens (see 2 papers)
    24% identity, 73% coverage of query (144 bits)

CAA68763.1 α-glucosidase A (GAA) (lysosomal) (EC 3.2.1.20) (see protein)
    24% identity, 73% coverage of query (144 bits)

ACU04898.1 α-galactosidase (PhGal31A;Phep_2697) (Gal31A) (EC 3.2.1.22) (see protein)
    24% identity, 72% coverage of query (142 bits)

CAI26256.1 glucosidase II, α-subunit (GII) (EC 3.2.1.20) (see protein)
glcaseIIa / CAI26256.1 glucosidase II, alpha subunit precursor from Trypanosoma brucei brucei (see paper)
    24% identity, 70% coverage of query (141 bits)

AAC39568.2 maltase-glucoamylase (MgaM;Mga;MGAML) (EC 3.2.1.20) (see protein)
    23% identity, 73% coverage of query (139 bits)

MGA_HUMAN / O43451 Maltase-glucoamylase; Alpha-1,4-glucosidase; EC 3.2.1.20 from Homo sapiens (Human) (see 8 papers)
    23% identity, 73% coverage of query (139 bits)

3l4uA / O43451 Crystal complex of n-terminal human maltase-glucoamylase with de-o- sulfonated kotalanol (see paper)
    22% identity, 73% coverage of query (139 bits)

3l4zA Crystal complex of n-terminal human maltase-glucoamylase with salacinol
    22% identity, 73% coverage of query (139 bits)

3l4yA Crystal complex of n-terminal human maltase-glucoamylase with nr4-8ii
    22% identity, 73% coverage of query (139 bits)

3l4xA Crystal complex of n-terminal human maltase-glucoamylase with nr4-8
    22% identity, 73% coverage of query (139 bits)

3l4wA Crystal complex of n-terminal human maltase-glucoamylase with miglitol
    22% identity, 73% coverage of query (139 bits)

3l4vA Crystal complex of n-terminal human maltase-glucoamylase with kotalanol
    22% identity, 73% coverage of query (139 bits)

2qmjA Crystral structure of the n-terminal subunit of human maltase- glucoamylase in complex with acarbose
    22% identity, 73% coverage of query (139 bits)

3l4tA Crystal complex of n-terminal human maltase-glucoamylase with bj2661
    22% identity, 73% coverage of query (139 bits)

3cttA Crystal complex of n-terminal human maltase-glucoamylase with casuarine
    23% identity, 73% coverage of query (138 bits)

ACH86011.1 membrane-bound maltase-glucoamylase (MGAM) (EC 3.2.1.20) (see protein)
    23% identity, 71% coverage of query (135 bits)

AAA31459.1 sucrase-isomaltase (SI) (EC 3.2.1.10|3.2.1.20|3.2.1.48) (see protein)
    24% identity, 90% coverage of query (135 bits)

3lppB / P14410 Crystal complex of n-terminal sucrase-isomaltase with kotalanol (see paper)
    24% identity, 73% coverage of query (132 bits)

SUIS_HUMAN / P14410 Sucrase-isomaltase, intestinal; EC 3.2.1.48; EC 3.2.1.10 from Homo sapiens (Human) (see 7 papers)
P14410 oligo-1,6-glucosidase (EC 3.2.1.10); sucrose alpha-glucosidase (EC 3.2.1.48) from Homo sapiens (see 6 papers)
    24% identity, 73% coverage of query (132 bits)

AAT18166.1 sucrase-isomaltase (SI) (EC 3.2.1.10|3.2.1.48) (see protein)
    24% identity, 73% coverage of query (132 bits)

6m77A / A0A125W693 Gh31 alpha-n-acetylgalactosaminidase from enterococcus faecalis in complex with n-acetylgalactosamine (see paper)
    24% identity, 72% coverage of query (117 bits)

7f7rA Enterococcus faecalis gh31 alpha-n-acetylgalactosaminidase d455n in complex with tn antigen
    24% identity, 72% coverage of query (115 bits)

7f7qA Enterococcus faecalis gh31 alpha-n-acetylgalactosaminidase d455a in complex with p-nitrophenyl alpha-n-acetylgalactosaminide
    24% identity, 72% coverage of query (114 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory